The global market for treatments for syndromes of progressive ataxia and
weakness disorders was valued at nearly $14 billion in 2011 and should reach
nearly $15 billion in 2012. Total market value is expected to reach nearly
$23.5 billion in 2017 after increasing at a five-year compound annual growth
rate (CAGR) of 9.4%.
Progressive ataxia treatments are expected to have a value of $356.4
million in 2012 and $620.7 million in 2017, a CAGR of 11.7%.
Treatments for Machado-Joseph disease should total $158.4 million in 2012
and $273.5 million in 2017, a CAGR of 11.5%.
SUMMARY FIGURE
GLOBAL MARKET FOR PROGRESSIVE ATAXIA AND WEAKNESS DISORDERS,
2010-2017 ($ MILLIONS)
Source: BCC Research
STUDY OBJECTIVES
BCC's goal in conducting this study is to provide an overview of the current
and future characteristics of the global market for treatments of
neurodegenerative (i.e., progressive ataxia and weakness) disorders. The key
objective is to present a comprehensive analysis and the future direction of
treatments for these disorders as the market efforts toward drug and therapy
development evolve.
This report explores present and future strategies within the progressive
ataxia and weakness disorders market, which includes treatments and therapies
for dysfunctions, including progressive ataxia and progressive weakness
disorder syndromes. The market's improvisation, setbacks and needs are also
discussed. The comparisons, usage, advantages and disadvantages of different
types of technologies, including small-molecule and monoclonal antibodies, are
also presented.
A detailed analysis of the industry structure has been conducted. Revenues
are broken down by the neurodegenerative dysfunction. Sales figures are
estimated for the five-year period from 2012 through 2017.
The report discusses applications for neurodegenerative disorder treatment and
therapy technologies, with emphasis on small-molecule and monoclonal
antibodies technology. The report also covers significant patents and their
allotments in each category.
REASONS FOR DOING THIS STUDY
Extensive research in the field of progressive ataxia and weakness disorders
as well as collaborations with research institutes have highlighted the
importance of understanding the nature of these disorders. New technology
development is providing modifying therapies for the late stages of these
disorders. Collaborations among research institutes and pharmaceutical
companies are becoming more common, as state-of-the-art technology is being
explored to develop more-efficient products and therapies.
R&D spending, increasing competition, patent expiries and new technologies are
shifting the market in a new direction. The market's overall revenue has
increased from 2009 to 2011, and it continues to show growth, as new
advancements, product launches and collaborations will have positive
influences for the foreseeable future. This study looks at most of the
systems affected by these factors.
Acquisition strategies and company collaborations are also covered in this
report. This study discusses the strength and weaknesses of each technology
in light of the new developments, growing competition and changing customer
needs.
SCOPE OF THE STUDY
The scope of this study encompasses the neurodegenerative (i.e., progressive
ataxia and weakness) disorders in the pharmaceutical and biotechnology
markets. BCC analyzes each market and its applications, the regulatory
environments, and the technologies involved, as well as market projections and
market shares. Technological issues include the latest trends and
developments. The emerging market for enzyme inhibitors includes such
countries as India, China, Japan, South Korea, Taiwan, Canada, Africa,
Australia and New Zealand.
METHODOLOGY
Both primary and secondary research methodologies were used in preparing this
study. BCC conducted a comprehensive literature search, which included
technical newsletters and journals, among other sources. Data were collected
through interviews and correspondence with technical experts at companies that
manufacture enzyme inhibitors. Projections were based on estimates that were
calculated such using information as the current number of end users,
potential end users, mergers and acquisitions, and market trends.
INFORMATION SOURCES
Many companies within the industry were surveyed to obtain data for this
study. These included manufacturers and end users of enzyme inhibitors in
therapeutic categories and various disease-sector industries. Data were
gathered from various industry sources. BCC spoke with officials within the
industry and also reviewed newsletters, company literature and product
literature, as well as a host of technical articles, journals, indices and
abstracts. Exhaustive investigations of databases by key terminology were
completed. In addition, data were compiled from current financial, trade and
government sources.
ABOUT THE AUTHOR
A team of professionals in the biotechnology industry has carried out this
study. Its project manager is Shalini S. Dewan, who holds a Master's
degree in pharmaceutical chemistry and has more than 14 years of industry
experience. She has covered such research topics as compounds of potential
pharmaceutical interest from ibuprofen and 2-naphthyl acetic acid. Shalini
was awarded a Gold Medal by the Prime Minister of India for her work, and she
has collaborated with top companies in India and in the U.S.
Table of Contents
Table of Contents
Global Markets for Treatments for Syndromes of Progressive Ataxia and Weakness Disorders -- Focus on Progressive Ataxia
Chapter - 1: INTRODUCTION - Complimentary
STUDY OBJECTIVES
REASONS FOR DOING THIS STUDY
CONTRIBUTIONS OF THE STUDY AND FOR WHOM
SCOPE OF THE STUDY
METHODOLOGY
INFORMATION SOURCES
ABOUT THE AUTHOR
RELATED BCC RESEARCH REPORTS
BCC ON-LINE SERVICES
DISCLAIMER
Chapter - 2: EXECUTIVE SUMMARY
Table Summary: GLOBAL MARKET FOR PROGRESSIVE ATAXIA AND WEAKNESS
DISORDERS, THROUGH 2017
Figure Summary: GLOBAL MARKET FOR PROGRESSIVE ATAXIA AND WEAKNESS
DISORDERS, 2010-2017
Chapter - 3: OVERVIEW
DEFINITIONS
CLASSIFICATION
PROGRESSIVE ATAXIA AND WEAKNESS DISORDERS
DIAGNOSTIC TESTS FOR PROGRESSIVE ATAXIA AND WEAKNESS DISORDERS
Chapter - 4: REGULATORY ASPECTS
DRUG APPROVALS FOR PROGRESSIVE ATAXIA AND WEAKNESS DISORDERS
REGULATORY DEVELOPMENTS OF PRODUCTS USED TO TREAT PROGRESSIVE ATAXIA AND
WEAKNESS DISORDERS
Chapter - 5: NEW DEVELOPMENTS
Table 6: NEW DEVELOPMENTS FOR THE TREATMENT OF PROGRESSIVE ATAXIA AND
WEAKNESS DISORDERS, 2012
Table 7: NEW DEVELOPMENTS FOR THE TREATMENT OF PROGRESSIVE ATAXIA AND
WEAKNESS DISORDERS, 2011
Table 8: NEW DEVELOPMENTS IN THE TREATMENT OF PROGRESSIVE ATAXIA AND
WEAKNESS DISORDERS, 2010
Chapter - 6: GLOBAL MARKETS
MARKETS BY DYSFUNCTION
MARKETS BY DISORDERS
MARKET BY REGIONS
MARKETS BY TECHNOLOGY
Chapter - 7: PROGRESSIVE ATAXIA SYNDROME MARKET
MARKET BY DISEASE TYPE
MARKET BY REGION
MARKET BY TECHNOLOGY
INDUSTRY STRUCTURE
Chapter - 8: PATENT ANALYSIS
PATENTS BY YEAR
PATENTS BY DISEASE CATEGORY
PATENTS BY DISEASE TYPE
PATENTS BY COUNTRY
PATENTS BY COMPANY
PATENTS BY ASSIGNEE
Chapter - 9: CURRENT SITUATION
MARKET TRENDS
ADDITIONAL DRIVERS FOR PROGRESSIVE ATAXIA AND WEAKNESS DISORDERS DRUG
MARKET
FACTORS GOVERNING THE MARKET
COLLABORATIONS, MERGERS AND ACQUISITIONS
Chapter - 10: COMPANY PROFILES
ABBOTT LABORATORIES
ACORDA THERAPEUTICS INC.
ACTAVIS ELIZABETH
ALLON THERAPEUTICS INC
AMERICAN REGENT INC.
APOTEX INC.
APOTHECA, INC.
APP PHARMACEUTICALS
ASTELLAS PHARMA INC.
ASTRAZENECA GMBH
AUROBINDO PHARMA LTD
BAXTER INTERNATIONAL INC.
BIOGEN IDEC
BOEHRINGER INGELHEIM LTD.
BRISTOL-MYERS SQUIBB
BRYANT RANCH PREPACK
CADILA HEALTHCARE LTD.
CARACO PHARMACEUTICAL LABORATORIES
CARDINAL HEALTH
COGNITION PHARMACEUTICALS LLC
CSL BEHRING
DR. REDDY'S LABORATORIES LIMITED
EISAI CO. LTD
ELAN PHARMA INTERNATIONAL LIMITED
ELI LILLY AND COMPANY
EMD MILLIPORE HEADQUARTERS
ENDO PHARMACEUTICALS INC
GLAXOSMITHKLINE PLC.
GLENMARK GENERICS LIMITED
H. LUNDBECK A/S
HAMELN PHARMACEUTICALS LTD
HOSPIRA INC.
INTELLECT NEUROSCIENCES INC.
JAZZ PHARMACEUTICALS PLC.
LEXICON PHARMACEUTICALS INC.
MAJOR PHARMACEUTICALS
MERCK SERONO
MERCK SHARP & DOHME LIMITED
MERZ PHARMA GMBH & CO KGAA
MOMENTA PHARMACEUTICALS
MYLAN PHARMACEUTICALS
NEUREN PHARMACEUTICALS LTD.
NEUROSEARCH A/S
NOSCIRA, S.A.
NOVARTIS AG
ORCHID CHEMICALS & PHARMACEUTICALS LTD.
ORTHO-MCNEIL JANSSEN PHARMACEUTICALS INC.
PAR PHARMACEUTICALS
PERRIGO COMPANY
PFIZER INC.
PHARNEXT
PHYSICIANS TOTAL CARE, INC.
PLIVA HRVATSKA D.O.O.
PROMETHEUS
RANBAXY LABORATORIES LIMITED
ROCHE HOLDING LTD
ROXANE LABORATORIES INC.
SANDOZ INTERNATIONAL GMBH
SANOFI
SANTHERA PHARMACEUTICALS
SHIONOGI & CO.
SUN PHARMA
TAJ PHARMACEUTICALS LIMITED
TAKEDA PHARMACEUTICAL COMPANY LIMITED
TERCICA, INC
TEVA PHARMACEUTICAL INDUSTRIES LTD
TORRENT PHARMA
UCB S.A.
UDL LABORATORIES
UPSHER-SMITH LABORATORIES
WATSON PHARMACEUTICALS INC.
WEST-WARD PHARMACEUTICAL
Chapter - 11: APPENDIX I: ABBREVIATIONS
List of Tables
Summary Table: GLOBAL MARKET FOR PROGRESSIVE ATAXIA AND WEAKNESS
DISORDERS, THROUGH 2017
Table 1: CLASSIFICATION BY PRIMARY DYSFUNCTION
Table 2: ABBREVIATED APPROVALS AND NEW DRUG APPROVALS FOR PROGRESSIVE
ATAXIA AND WEAKNESS DISORDERS, 2012
Table 3: NEW DRUG APPLICATIONS FOR THE PROGRESSIVE ATAXIA AND WEAKNESS
DISORDERS
Table 4: SAFETY ALERTS, 2010-MARCH 2012
Table 5: RECALLS FOR DRUGS USED TO TREAT PROGRESSIVE ATAXIA AND WEAKNESS
DISORDERS, 2010 - MARCH 2012
Table 6: NEW DEVELOPMENTS FOR THE TREATMENT OF PROGRESSIVE ATAXIA AND
WEAKNESS DISORDERS, 2012
Table 7: NEW DEVELOPMENTS FOR THE TREATMENT OF PROGRESSIVE ATAXIA AND
WEAKNESS DISORDERS, 2011
Table 8: NEW DEVELOPMENTS IN THE TREATMENT OF PROGRESSIVE ATAXIA AND
WEAKNESS DISORDERS, 2010
Table 9: GLOBAL REVENUES OF DRUG PRODUCTS FOR THE TREATMENT OF
NEURODEGENERATIVE DYSFUNCTIONS, THROUGH 2017
Table 10: MARKET SHARE OF DRUGS USED FOR THE TREATMENT OF
NEURODEGENERATIVE DISORDERS BY DYSFUNCTIONS, 2011
Table 11: GLOBAL SALES OF DRUG PRODUCTS FOR THE TREATMENT OF PROGRESSIVE
ATAXIA AND WEAKNESS DISORDERS, THROUGH 2017
Table 12: MARKET SHARE OF DRUG PRODUCTS FOR THE TREATMENT OF PROGRESSIVE
ATAXIA AND WEAKNESS DISORDERS, 2011
Table 13: MARKET FOR DRUG PRODUCTS FOR THE TREATMENT OF PROGRESSIVE
ATAXIA AND WEAKNESS DISORDERS BY REGION, THROUGH 2017
Table 14: MARKET SHARE OF DRUG PRODUCTS FOR THE TREATMENT OF PROGRESSIVE
ATAXIA AND WEAKNESS DISORDERS BY REGION, 2011
Table 15: GLOBAL SALES OF DRUG PRODUCTS FOR THE TREATMENT OF PROGRESSIVE
ATAXIA AND WEAKNESS DISORDERS BY TECHNOLOGY, THROUGH 2017
Table 16: MARKET SHARE OF DRUG PRODUCTS FOR THE TREATMENT OF PROGRESSIVE
ATAXIA AND WEAKNESS DISORDERS BY TECHNOLOGY, 2011
Table 17: SALES OF DRUG PRODUCTS FOR THE TREATMENT OF PROGRESSIVE ATAXIA
BY DISEASE TYPE, THROUGH 2017
Table 18: PROGRESSIVE ATAXIA DRUG MARKET BY DISEASE TYPE, 2011
Table 19: PROGRESSIVE ATAXIA DRUG MARKET BY REGION, THROUGH 2017
Table 20: PROGRESSIVE ATAXIA DRUG MARKET BY REGION, 2011
Table 21: FRIEDREICH'S ATAXIA DRUG MARKET BY REGION, THROUGH 2017
Table 22: GERTSMANN-STRAUSSLER-SCHEINKER DISEASE DRUG MARKET BY REGION,
THROUGH 2017
Table 23: MACHADO-JOSEPH DISEASE DRUG MARKET BY REGION, THROUGH 2017
Table 24: PROGRESSIVE ATAXIA DRUG MARKET BY TECHNOLOGY, THROUGH 2017
Table 25: PROGRESSIVE ATAXIA DRUGS SHARE BY TECHNOLOGY, 2011
Table 26: LEADING MANUFACTURERS AND SUPPLIERS OF FRIEDREICH'S ATAXIA
DRUGS AND THERAPIES
Table 27: MARKET SHARES FOR MANUFACTURERS AND DISTRIBUTORS OF
FRIEDREICH'S ATAXIA DRUGS, 2011
Table 28: LEADING MANUFACTURERS AND SUPPLIERS OF
GERSTMANN-STRAUSSLER-SCHEINKER DISEASE DRUGS AND THERAPIES
Table 29: MARKET SHARES OF MANUFACTURERS AND DISTRIBUTORS OF
GERTSMANN-STRAUSSLER-SCHEINKER DISEASE DRUGS, 2011
Table 30: LEADING MANUFACTURERS AND SUPPLIERS OF MACHADO-JOSEPH DISEASE
DRUGS AND THERAPIES
Table 31: MARKET SHARES OF MANUFACTURERS AND DISTRIBUTORS OF
MACHADO-JOSEPH DISEASE DRUGS, 2011
Table 32: TOTAL NUMBER OF PATENTS BY YEAR, 2010-MARCH 2012
Table 33: PATENTS BY DISEASE CATEGORY, 2010-MARCH 2012
Table 34: PATENTS FOR PROGRESSIVE ATAXIA SYNDROMES BY DISEASE TYPE, 2010
- 2012
Table 35: PATENTS FOR PROGRESSIVE WEAKNESS AND EFFECT THE ON BRAIN AND
SPINAL CORD SYNDROMES BY DISEASE TYPE, 2010 - 2012
Table 36: U.S. PATENTS BY COUNTRY FOR PROGRESSIVE ATAXIA SYNDROMES, 2010
- 2012
Table 37: PATENT SHARES BY COUNTRY FOR PROGRESSIVE ATAXIA SYNDROMES,
2010 - 2012
Table 38: U.S. PATENTS BY COUNTRY FOR PROGRESSIVE WEAKNESS AND EFFECT ON
THE BRAIN AND SPINAL CORD SYNDROMES, 2010-2012
Table 39: PATENT SHARES BY COUNTRY FOR PROGRESSIVE WEAKNESS AND EFFECT
ON THE BRAIN AND SPINAL CORD SYNDROMES, 2010 - 2012
Table 40: U.S. PATENTS FOR PROGRESSIVE ATAXIA SYNDROMES BY COMPANY, 2010
- 2012
Table 41: U.S. PATENTS FOR PROGRESSIVE WEAKNESS AND EFFECT ON THE BRAIN
AND SPINAL CORD SYNDROMES BY COMPANY, 2010-2012
Table 42: PATENTS FOR PROGRESSIVE ATAXIA SYNDROMES BY ASSIGNEE, 2010 -
2012
Table 43: PATENTS FOR PROGRESSIVE WEAKNESS AND EFFECT ON THE BRAIN AND
SPINAL CORD SYNDROMES BY ASSIGNEE, 2010 - 2012
List of Figures
Summary Figure: GLOBAL MARKET FOR PROGRESSIVE ATAXIA AND WEAKNESS
DISORDERS, 2010-2017
Figure 1: GLOBAL REVENUES OF DRUG PRODUCT FOR THE TREATMENT OF
NEURODEGENERATIVE DYSFUNCTIONS, 2010-2017
Figure 2: MARKET SHARE OF DRUG USED FOR THE TREATMENT OF
NEURODEGENERATIVE DISORDERS BY DYSFUNCTION, 2011
Figure 3: GLOBAL SALES OF DRUG PRODUCT FOR THE TREATMENT OF PROGRESSIVE
ATAXIA AND WEAKNESS DISORDERS, 2010-2017
Figure 4: MARKET SHARE OF DRUG PRODUCTS FOR THE TREATMENT OF PROGRESSIVE
ATAXIA AND WEAKNESS DISORDERS, 2011
Figure 5: MARKET FOR DRUG PRODUCTS FOR THE TREATMENT OF PROGRESSIVE
ATAXIA AND WEAKNESS DISORDERS BY REGION, 2010-2017
Figure 6: MARKET SHARE OF DRUG PRODUCTS FOR THE TREATMENT OF PROGRESSIVE
ATAXIA AND WEAKNESS DISORDERS BY REGION, 2011
Figure 7: GLOBAL SALES OF DRUG PRODUCTS FOR THE TREATMENT OF PROGRESSIVE
ATAXIA AND WEAKNESS DISORDERS BY TECHNOLOGY, 2010-2017
Figure 8: MARKET SHARE OF DRUG PRODUCTS FOR THE TREATMENT OF PROGRESSIVE
ATAXIA AND WEAKNESS DISORDERS BY TECHNOLOGY, 2011
Figure 9: SALES OF DRUG PRODUCTS FOR THE TREATMENT OF PROGRESSIVE ATAXIA
BY DISEASE TYPE, 2010-2017
Figure 10: PROGRESSIVE ATAXIA DRUG MARKET BY DISEASE TYPE, 2011
Figure 11: PROGRESSIVE ATAXIA DRUG MARKET BY REGION, 2010-2017
Figure 12: PROGRESSIVE ATAXIA DRUG MARKET BY REGION, 2011
Figure 13: FRIEDREICH'S ATAXIA DRUG MARKET BY REGION, 2010-2017
Figure 14: GERTSMANN-STRAUSSLER-SCHEINKER DISEASE DRUG MARKET BY REGION,
2010-2017
Figure 15: MACHADO-JOSEPH DISEASE DRUG MARKET BY REGION, 2010-2017
Figure 16: PROGRESSIVE ATAXIA DRUG MARKET BY TECHNOLOGY, 2010-2017
Figure 17: PROGRESSIVE ATAXIA DRUGS SHARE BY TECHNOLOGY, 2011
Figure 18: MARKET SHARES OF MANUFACTURERS AND DISTRIBUTORS OF
FRIEDREICH'S ATAXIA DRUGS, 2011
Figure 19: MARKET SHARES OF MANUFACTURERS AND DISTRIBUTORS OF
GERTSMANN-STRAUSSLER-SCHEINKER DISEASE DRUGS, 2011
Figure 20: MARKET SHARES OF MANUFACTURERS AND DISTRIBUTORS OF
MACHADO-JOSEPH DISEASE DRUGS, 2011
Figure 21: NUMBER OF PATENTS BY YEAR, 2010-MARCH 2012
Figure 22: PATENTS BY DISEASE CATEGORY, 2010-MARCH 2012
Figure 23: PATENTS FOR PROGRESSIVE ATAXIA SYNDROMES BY DISEASE TYPE,
2010-2012
Figure 24: PATENTS FOR PROGRESSIVE WEAKNESS AND EFFECT ON BRAIN AND
SPINAL CORD SYNDROMES BY DISEASE TYPE, 2010-2012
Global Markets for Treatments for Syndromes of Progressive Ataxia and Weakness Disorders -- Focus on Progressive Ataxia published by BCC Research in October 18, 2012. This report consists of 124 Pages and the price starts from US $ 4400.
