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Triple Analysis: Leukemia, Cancer Vaccines and Protein Kinase Inhibitors

Abstract

This triple analysis focuses on cancer drug development strategies in Leukemia and by the two mechanism/target/effect areas of Cancer Vaccines and Protein Kinase Inhibitors. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.

Table of Contents

Key Topics Covered:

Part I: Leukemia

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target Among Leukemia Drugs for the Highest Therapeutic Outcome and Return on Investment (204 Drug Targets)
  • 7. Emerging New Products to Established Ones: Drug Target Strategies of Leukemia Drugs by their Highest Stage of Development (193 Drug Target Strategies and 313 Leukemia Drugs)
  • 8. Compound Strategies at Work: Competitive Benchmarking of Leukemia Drugs by Compound Strategy (8 Compound Strategies)
  • 9. Selecting Subindication for Leukemia Drugs (8 Subindications of Leukemia)
  • 10. Pipeline and Portfolio Planning: Competitive Benchmarking of the Leukemia Drug Pipeline by Investigator (186 Companies)
  • 11. Disclaimer
  • 12. Drug Index
  • 13. Company Index
  • Figures: Includes 6 Figures
  • Tables: Includes 253 Tables
  • Total Number of Pages: 1,147

Part II: Cancer Vaccines

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target Among Cancer Vaccine Drugs for the Highest Therapeutic Outcome and Return on Investment (94 Drug Targets)
  • 7. Emerging New Products to Established Ones: Drug Target Strategies of Cancer Vaccine Drugs by their Highest Stage of Development (91 Drug Target Strategies and 155 Cancer Vaccine Drugs)
  • 8. Compound Strategies at Work: Competitive Benchmarking of Cancer Vaccine Drugs by Compound Strategy (7 Compound Strategies)
  • 9. Selecting Cancer Indications for Cancer Vaccine Drugs (42 Cancer Indications)
  • 10. Pipeline and Portfolio Planning: Competitive Benchmarking of the Cancer Vaccine Drug Pipeline by Investigator (99 Investigators)
  • 11. Disclaimer
  • 12. Drug Index
  • 13. Company Index
  • Figures: Includes 6 Figures
  • Tables: Includes 205 Tables
  • Total Number of Pages: 659

Part III: Protein Kinase Inhibitors

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (133 Drug Targets)
  • 7. The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Profiles Identified in the Cancer Protein Kinase Therapeutic Pipeline? (200 Drug Target Strategies and 409 Drugs)
  • 8. Compound Strategies at Work: Competitive Benchmarking of Protein Kinase Drugs in Oncology by Compound Type (7 Compound Strategies)
  • 9. Selecting Cancer Indications for Protein Kinase Therapeutics (57 Different Cancer Indications)
  • 10. Portfolio Planning: Competitive Benchmarking of Protein Kinase Cancer Therapeutic Pipeline by Investigator (160 Investigators)
  • 12. Drug Index
  • 13. Company Index
  • Figures: Includes 6 Figures
  • Tables: Includes 302 Tables
  • Total Number of Pages: 1442

Featured Companies:

This Report Includes the Following Companies:

  • 3M Pharmaceuticals
  • 4SC
  • Abbott
  • Abiogen
  • Abraxis BioScience
  • AC Immune
  • Actinium Pharmaceuticals
  • Adaptimmune
  • Aduro BioTech
  • Advaxis
  • Advenchen
  • AEgera
  • Aeterna Zentaris
  • Agenus
  • Aida Pharmaceuticals
  • Akela Pharma
  • Alethia Biotherapeutics
  • Alexion
  • Alfa Wassermann
  • AlphaVax
  • Altor BioScience
  • Ambit Biosciences
  • Amgen
  • Amphora
  • Antisoma
  • Apthera
  • Arca biopharma
  • Ariad
  • Arno Therapeutics
  • ArQule
  • Array BioPharma
  • Asahi Kasei Pharma
  • Ascenta Therapeutics
  • Astellas
  • Astex Therapeutics
  • AstraZeneca
  • Attenuon
  • AVI BioPharma
  • Bavarian Nordic
  • Bayer
  • Bellicum Pharmaceuticals
  • Bio-Path Holdings
  • BioAxone
  • BioCryst Pharmaceuticals
  • Bioenvision
  • Biogen Idec
  • BioSante
  • Biostar
  • Biotecnol
  • Bioton
  • BioVex
  • Boehringer Ingelheim
  • Bristol-Myers Squibb
  • BTG
  • Cadila
  • Callisto Pharmaceuticals
  • Cancer Research Technology
  • Celator Pharmaceuticals
  • Celera
  • Celgene
  • Cell Genesys
  • Cell Therapeutics
  • Celldex Therapeutics
  • Cephalon
  • CG Therapeutics
  • Choongwae
  • CJ Corp
  • Clavis Pharma
  • CompleGen
  • Cornerstone Pharmaceuticals
  • Cosmo Pharmaceuticals
  • CSL
  • Curacyte
  • CureTech
  • Curis
  • Cyclacel
  • Cylene Pharmaceuticals
  • CytImmune Sciences
  • Cytokinetics
  • Daiichi Sankyo
  • Dainippon Sumitomo Pharma
  • Dara Biosciences
  • Deciphera Pharmaceuticals
  • Dendreon
  • DeveloGen
  • DiaMedica
  • Dong-A
  • Dyax
  • Eisai
  • Elara Pharmaceuticals
  • Eleos
  • Eli Lilly
  • Emergent BioSolutions
  • Enkam Pharmaceuticals
  • EntreMed
  • Enzon
  • Epeius Biotechnologies
  • EpiCept
  • Epizyme
  • Erimos
  • Esperance Pharmaceuticals
  • Exelixis
  • ExonHit Therapeutics
  • Gemin X Biotechnologies
  • Genencor
  • Genentech
  • Generex
  • Genmab
  • GenOdyssee Pharmaceuticals
  • Genta
  • GENTICEL
  • Genzyme
  • Geron
  • Gilead Sciences
  • GlaxoSmithKline
  • Gliknik
  • GlobeImmune
  • GlycoGenesys
  • GlycoMimetics
  • Gradalis
  • Hanmi
  • Hayashibara
  • Heber Biotec
  • Hoffmann-La Roche
  • Ichor Medical Systems
  • Idera Pharmaceuticals
  • IDM Pharma
  • IkerChem
  • ImClone Systems
  • Immune Pharmaceuticals
  • ImmunoCellular Therapeutics
  • Immunocore
  • ImmunoFrontier
  • ImmunoGen
  • Immunomedics
  • Immunotope
  • Incyte Corporation
  • InDex Pharmaceuticals
  • Inex
  • Innate Pharma
  • Innovive
  • Inovio
  • Insmed
  • Insys Therapeutics
  • Intas Biopharmaceuticals
  • Introgen Therapeutics
  • ISA Pharmaceuticals
  • Isis Pharmaceuticals
  • ISU ABXIS
  • Italfarmaco
  • Johnson & Johnson
  • KAI Pharmaceuticals
  • KaloBios
  • Kalypsys
  • Kanisa
  • Kiadis
  • Kinex
  • Kirin Pharma
  • Kyowa Hakko Kirin
  • Leo
  • LFB Biotechnologies
  • LG Life Sciences
  • Ligand
  • Locus Pharmaceuticals
  • Lorus Therapeutics
  • MAT Biopharma
  • MaxCyte
  • MaxoCore Pharmaceuticals
  • Meda
  • Medical Marketing International
  • MediGene
  • Medisyn Technologies
  • Memgen
  • Menarini
  • Merck & Co
  • Merck KGaA
  • MethylGene
  • Micromet
  • Mitsubishi Tanabe Pharma
  • MolMed
  • Mologen
  • Nemod Biotherapeutics
  • NeoPharm
  • Neovacs
  • Nereus Pharmaceuticals
  • Nerviano Medical Sciences
  • NicOx
  • Nidus Laboratories
  • NIH
  • Nippon Shinyaku
  • Non-industrial source
  • Northwest Biotherapeutics
  • Novartis
  • NovaRx
  • Novogen
  • Oncalis
  • OncoMune
  • Onconova
  • OncoTherapy Science
  • Oncothyreon
  • Oncovir
  • Onyvax
  • OSI Pharmaceuticals
  • Otsuka
  • Oxford BioMedica
  • Pepscan Systems
  • Pepscan Therapeutics
  • Peregrine Pharmaceuticals
  • Pfizer
  • Pharmacyclics
  • PharmaGap
  • PharmaMar
  • Pharmexa
  • PIERIS Proteolab
  • Pierre Fabre
  • Piramal
  • Plexxikon
  • Portola Pharmaceuticals
  • Prima Biomed
  • Prochon Biotech
  • Progenics Pharmaceuticals
  • ProMetic Life Sciences
  • Protherics
  • Radient Pharmaceuticals
  • Reata Pharmaceuticals
  • Receptor BioLogix
  • Reliance Life Sciences
  • responsif
  • Rexahn
  • Rigel
  • Sangamo BioSciences
  • Sanofi-Aventis
  • Santaris Pharma
  • Sareum
  • SBI Biotech
  • SBIO
  • Scancell
  • Schering-Plough
  • SciClone Pharmaceuticals
  • Seattle Genetics
  • Semafore Pharmaceuticals
  • Sepal Pharma
  • Servier
  • Shenogen
  • Shire
  • Sidus
  • Southern Research Institute
  • Spirogen
  • Stemline Therapeutics
  • SuperGen
  • Supratek Pharma
  • Swedish Orphan Biovitrum
  • Switch Pharma
  • SymBio Pharmaceuticals
  • Symbiotec
  • Synageva BioPharma
  • Synta Pharmaceuticals
  • Syntrix
  • Takeda
  • Talon Therapeutics
  • TapImmune
  • Targa Therapeutics
  • TargeGen
  • TeGenero
  • Telik
  • Teva
  • Thallion Pharmaceuticals
  • Therion Biologics
  • ToolGen
  • TopoTarget
  • Transgene
  • Trion Pharma
  • UCB
  • United Biomedical
  • Vaccinex
  • Valeant
  • Vaxil BioTherapeutics
  • Vaxon Biotech
  • VaxOnco
  • Vectura
  • Vertex Pharmaceuticals
  • Vical
  • Vion Pharmaceuticals
  • VioQuest Pharmaceuticals
  • Viragen
  • Virionics
  • ViroMed
  • Wyeth
  • XBiotech
  • Xencor
  • Yamasa Corporation
  • Zensun
  • Zenyaku Kogyo
  • A Shortlist of Drugs Included are:
  • ADXS11-001
  • AE-37
  • alemtuzumab
  • ALVAC-CEA/B7.1
  • alvocidib
  • amonafide malate
  • amsacrine
  • ARQ-197
  • astuprotimut-r
  • AVX-701
  • axitinib
  • barasertib
  • belagenpumatucel-L
  • belinostat
  • BIBW-2992
  • bisantrene
  • bosutinib
  • BP-GMAX-CD1
  • brivanib alaninate
  • Cadi-05
  • CB-10-01
  • CEA-TRICOM
  • cediranib
  • CG-201
  • cladribine
  • clofarabine
  • CMLVAX-100
  • CSF-GM
  • CTL901
  • CTP-37
  • CVac
  • cytarabine ocfosfate
  • cytarabine, injectable
  • dasatinib
  • daunorubicin
  • DCVax-prostate
  • decitabine
  • deforolimus
  • E-75
  • elacytarabine
  • enocitabine
  • enzastaurin hydrochloride
  • erlotinib
  • everolimus
  • fowlpox-PSA vaccine
  • gefitinib
  • gemtuzumab ozogamicin
  • GRNVAC1
  • GV-1001
  • GV-1002
  • GVAX
  • GVX-3322
  • Her-2/Neu peptides
  • histamine dihydrochloride
  • idarubicin
  • idronoxil
  • IGN-101
  • imatinib mesilate
  • ImmunoVEX tri-melan
  • IMO-2055
  • INGN-225
  • interferon
  • interferon (alpha-N1)
  • interferon (alpha)
  • interferon (alpha2)
  • interferon (alpha2a)
  • interferon (alpha2b)
  • interferon (alpha2c)
  • interferon (gamma)
  • interferon alpha-2b
  • lapatinib ditosylate
  • lestaurtinib
  • leukemia vaccine
  • lumiliximab
  • MAGE-3-TK
  • ME-103
  • MGN-1601
  • midostaurin
  • mitoxantrone
  • motesanib diphosphate
  • MSI vaccine
  • MVA-BN
  • MVA-BN Her-2 vaccine
  • nilotinib
  • Norelin
  • obinutuzumab
  • oblimersen sodium
  • ofatumumab
  • ON-01910
  • Onyvax-105
  • OTS-102
  • PANVAC-VF
  • pazopanib hydrochloride
  • pDOM-PSMA27
  • peginterferon alfa-2b
  • pentostatin
  • PEP-223
  • poly-ICLC
  • PR1:169-177 peptide
  • PROSTVAC
  • PX-104.1
  • ramucirumab
  • razoxane
  • Reximmune-C
  • rhIFN-alpha
  • rindopepimut
  • rituximab
  • SAI-EGF
  • sobuzoxane
  • sorafenib tosylate
  • Stimuvax
  • sunitinib malate
  • tamibarotene
  • tanespimycin
  • temsirolimus
  • teniposide
  • TG-4001
  • TG-4010
  • thymalfasin
  • tipifarnib
  • TroVax
  • vandetanib
  • verpasep caltespen
  • vosaroxin
  • VX-001
  • XL-184
  • zorubicin
  • ZYC-300
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