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Triple Analysis: Prostate Cancer, Protein Kinase Inhibitors and Antibodies

Abstract

This triple analysis focuses on cancer drug development strategies in one specific cancer indication (Prostate Cancer), one mechanism/target/effect area (Protein Kinase Inhibitors) and one compound specific area (Antibodies). Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.

Table of Contents

Key Topics Covered:

Part I: Prostate Cancer

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target Among Prostate Cancer Drugs for the Highest Therapeutic Outcome and Return on Investment (227 Drug Targets)
  • 7. Emerging New Products to Established Ones: Drug Target Strategies of Prostate Cancer Drugs by their Highest Stage of Development (216 Drug Target Strategies and 394 Drugs)
  • 8. Compound Strategies at Work: Competitive Benchmarking of Prostate Cancer Drugs by Compound Strategy (8 Compound Strategies)
  • 9. Pipeline and Portfolio Planning: Competitive Benchmarking of the Prostate Cancer Drug Pipeline by Investigator (222 Investigators and 394 Drugs)
  • 10. Disclaimer
  • Figures: Includes 8 Figures
  • Tables: Includes 283 Tables
  • Total Number of Pages: 1,493

Part II: Protein Kinase Inhibitors

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target Among Protein Kinase Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (183 Drug Targets)
  • 7. Emerging New Products to Established Ones: Drug Target Strategies of Protein Kinase Drugs in Oncology by their Highest Stage of Development (278 Drug Target Strategies and 648 Drugs)
  • 8. Compound Strategies at Work: Competitive Benchmarking of Protein Kinase Cancer Drugs by Compound Strategy (8 Compound Strategies)
  • 9. Selecting Indication for Protein Kinase Drugs in Oncology (70 Cancer Indications)
  • 10. Pipeline and Portfolio Planning: Competitive Benchmarking of the Protein Kinase Drug Pipeline in Oncology by Investigator (212 Investigators and 648 Drugs)
  • 11. Disclaimer
  • Figures: Includes 8 Figures
  • Tables: Includes 389 Tables
  • Total Number of Pages: 2,940

Part III: Antibodies

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target Among Antibody Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (255 Drug Targets)
  • 7. Emerging New Products to Established Ones: Drug Target Strategies of Antibody Drugs in Oncology by their Highest Stage of Development (266 Drug Targets Strategies and 531 Antibody Drugs)
  • 8. Selecting Cancer Indication for Antibody Drugs (75 Cancer Indications)
  • 9. Pipeline and Portfolio Planning: Competitive Benchmarking of the Antibody Drug Pipeline in Oncology by Investigator (196 Investigators and 531 Antibody Drugs)
  • 10. Disclaimer
  • 11. Drug Index
  • 12. Company Index
  • Figures: Includes 5 Figures
  • Tables: Includes 347 Tables
  • Total Number of Pages: 1,944

This Report Includes the Following Companies:

  • 4SC
  • A&G Pharmaceutical
  • AB Science
  • Abbott
  • Abiogen
  • Ablynx
  • AC Immune
  • Acceleron Pharma
  • Access
  • ACT Biotech
  • Actinium Pharmaceuticals
  • Active Biotech
  • Adherex
  • Advantagene
  • Advenchen
  • AEgera
  • AEterna Zentaris
  • Affibody
  • Affimed Therapeutics
  • Affitech
  • AGY Therapeutics
  • Aida Pharmaceuticals
  • Alchemia
  • Alder Biopharmaceuticals
  • Alethia Biotherapeutics
  • Alexion
  • Alfacell
  • Algeta
  • Allist Pharmaceuticals
  • Allos Therapeutics
  • Allostera
  • AlphaVax
  • Alseres Pharmaceuticals
  • ALSP
  • Altor BioScience
  • Ambit Biosciences
  • Ambrilia Biopharma
  • American Gene Technology International
  • Amgen
  • Amorfix Life Sciences
  • Amphora
  • Anavex Life Sciences
  • AndroBioSys
  • Ansaris
  • Antisense Pharma
  • Antisense Therapeutics
  • Antisoma
  • Aphios
  • Apogee Biotechnology
  • ApopLogic Pharmaceuticals
  • Apotex
  • Aprea
  • Apricus Biosciences
  • Arana Therapeutics
  • Arca biopharma
  • Ardana
  • arGEN-X
  • Ariad
  • Arno Therapeutics
  • ArQule
  • Array BioPharma
  • Ascenta Therapeutics
  • Ascepion Pharmaceuticals
  • Astellas
  • Astex Pharmaceuticals
  • AstraZeneca
  • Attenuon
  • Avaxia
  • AVEO
  • AVI BioPharma
  • Avila Therapeutics
  • Bavarian Nordic
  • Baxter International
  • Bayer
  • Bellicum Pharmaceuticals
  • Benitec
  • Berkeley Lab
  • Bio-Path Holdings
  • BioAxone
  • Biocon
  • Bioenvision
  • Biogen Idec
  • BioInvent
  • Biolex
  • BioLineRx
  • BioMarin
  • BioNetWorks
  • Bionovo
  • BioSante
  • Biosceptre
  • Biostar
  • Biotecnol
  • Biotest
  • Biotica Technology
  • Boehringer Ingelheim
  • Bristol-Myers Squibb
  • BTG
  • Callisto Pharmaceuticals
  • Cambrex
  • Camurus
  • CanBas
  • Cancer Innovations
  • Cancer Research Technology
  • Catalyst Biosciences
  • Cel-Sci
  • Celgene
  • Cell Therapeutics
  • CellCeutix
  • Celldex Therapeutics
  • Celleron
  • Celltrion
  • Celsion
  • Celtic Pharma
  • Center of Molecular Immunology
  • Cephalon
  • CerRx
  • CG Therapeutics
  • Chemokine Therapeutics
  • Chroma Therapeutics
  • Circadian Technologies
  • Cleveland BioLabs
  • Clinical Data
  • Colby
  • CompleGen
  • Compugen
  • CoNCERT Pharmaceuticals
  • Cosmo Bioscience
  • CSL
  • CuraGen
  • Curaxis
  • CureTech
  • Curis
  • Cyclacel
  • Cylene Pharmaceuticals
  • CytImmune Sciences
  • Cytokine PharmaSciences
  • Cytokinetics
  • Cytopia
  • Daiichi Sankyo
  • Dainippon Sumitomo Pharma
  • Debiopharm
  • Deciphera Pharmaceuticals
  • Dendreon
  • DeveloGen
  • DiaMedica
  • Dompe
  • Dongkook Pharm
  • Dr Reddy's
  • Dyax
  • ECI
  • Eisai
  • Elan
  • Elara Pharmaceuticals
  • Eli Lilly
  • Emergent BioSolutions
  • Endo Pharmaceuticals
  • Endocyte
  • Enkam Pharmaceuticals
  • Ensemble Discovery
  • EntreMed
  • Enzon
  • EpiCept
  • Epitomics
  • Erimos
  • Esperance Pharmaceuticals
  • Etubics
  • EUSA Pharma
  • Exelixis
  • Faron Pharmaceuticals
  • Favrille
  • Femta Pharmaceuticals
  • Ferring
  • FibroGen
  • Five Prime Therapeutics
  • Formula Pharmaceuticals
  • Fusion Antibodies
  • Galapagos
  • Galaxy Biotech
  • Galena Biopharma
  • GammaCan
  • Ganymed Pharmaceuticals
  • Gemin X Pharmaceuticals
  • Gene Techno Science
  • Genencor
  • Genentech
  • Generex
  • Genmab
  • Genomic Systems
  • GENova Biotherapeutics
  • Genovax
  • GenPat77
  • Genta
  • Gerolymatos
  • Geron
  • Gilead Sciences
  • GlaxoSmithKline
  • Gliknik
  • GlycoGenesys
  • Glycotope
  • Got-a-Gene
  • GP Pharm
  • GPC Biotech
  • Green Cross
  • GTx
  • Hanmi
  • Harbor BioSciences
  • Hawthorn Pharmaceuticals
  • Hoffmann-La Roche
  • Human Genome Sciences
  • Hutchison China MediTech
  • Hypha Discovery
  • Idera Pharmaceuticals
  • IDM Pharma
  • IGF Oncology
  • ImClone Systems
  • IMED
  • Immune Pharmaceuticals
  • ImmunoCellular Therapeutics
  • Immunocore
  • ImmunoFrontier
  • ImmunoGen
  • Immunomedics
  • ImmuPharma
  • Immutep
  • Incozen Therapeutics
  • Incyte Corporation
  • Infinity Pharmaceuticals
  • Inhibiton Therapeutics
  • Innate Pharma
  • InNexus Biotechnology
  • Inovio
  • Insmed
  • Insys Therapeutics
  • Intellikine
  • Intracel
  • Introgen Therapeutics
  • Ipsen
  • ISA Pharmaceuticals
  • Isis Pharmaceuticals
  • ISU ABXIS
  • Ivy Medical Chemicals
  • Jina Pharmaceuticals
  • Johnson & Johnson
  • Kadmon
  • KAI Pharmaceuticals
  • Kaketsuken
  • KaloBios
  • Kalypsys
  • Karo Bio
  • Karus Therapeutics
  • Keryx Biopharmaceuticals
  • Kiadis
  • Kinex
  • Kirin Pharma
  • Kissei
  • KuDOS
  • Kyowa Hakko Kirin
  • Kyto Biopharma
  • Leo
  • Lexicon Pharmaceuticals
  • LFB Biotechnologies
  • LG Life Sciences
  • Ligand
  • Lorus Therapeutics
  • MacroGenics
  • Mannkind
  • Marillion Pharmaceuticals
  • Marina Biotech
  • MAT Biopharma
  • MaxoCore Pharmaceuticals
  • Med Discovery
  • Meda
  • Medarex
  • MediGene
  • MedImmune
  • Mediolanum
  • Medisyn Technologies
  • Medivation
  • Menarini
  • Merck & Co
  • Merck KGaA
  • Merrimack
  • Merrion Pharmaceuticals
  • MethylGene
  • Micromet
  • Mitsubishi Tanabe Pharma
  • Mojave Therapeutics
  • Molecular Insight
  • Molecular LogiX
  • Mycenax
  • Myrexis
  • Nano Terra
  • Nektar Therapeutics
  • Neovacs
  • Nereus Pharmaceuticals
  • Nerviano Medical Sciences
  • Neuren
  • Neurocrine Biosciences
  • NexusPharma
  • NicOx
  • Nidus Laboratories
  • NIH
  • Nippon Shinyaku
  • NKT Therapeutics
  • Non-industrial source
  • Northwest Biotherapeutics
  • Novacea
  • NovaLead
  • Novartis
  • Novogen
  • Oasmia
  • Oncalis
  • OncoGenex Pharmaceuticals
  • OncoMed
  • Onconova
  • OncoTherapy Science
  • Oncothyreon
  • Oncovir
  • Onyvax
  • Orion Pharma
  • OSI Pharmaceuticals
  • Oxford BioMedica
  • Paladin Labs
  • Panacea
  • PanGenetics
  • Pantarhei Bioscience
  • Pathway Therapeutics
  • Patrys
  • Pepscan Therapeutics
  • Peregrine Pharmaceuticals
  • Perseus Proteomics
  • Pfizer
  • Pharmacyclics
  • PharmaGap
  • PharmaMar
  • Pharmexa
  • Philogen
  • Phoenix Biotechnology
  • PHusis Therapeutics
  • Pieris
  • Pierre Fabre
  • Piramal
  • PIramed
  • Portola Pharmaceuticals
  • Prima Biomed
  • Proacta
  • ProCell Therapeutics
  • Prochon Biotech
  • Progen
  • Progenics Pharmaceuticals
  • ProNAi Therapeutics
  • ProStrakan
  • Provid
  • Q Chip
  • QLT
  • Quantum Pharmaceuticals
  • Ramot
  • Ras Therapeutics
  • Reata Pharmaceuticals
  • Recepta biopharma
  • Receptor BioLogix
  • Regeneron
  • Regulon
  • Rexahn
  • Rigel
  • Salzburg Therapeutics
  • Samtheo Biopharma
  • Samyang
  • Sanofi
  • Sanofi-Aventis
  • Santaris Pharma
  • Sapphire Therapeutics
  • Sareum
  • SBI Biotech
  • SBIO
  • Scancell
  • Schering-Plough
  • Seattle Genetics
  • SeleXel
  • Selvita
  • Semafore Pharmaceuticals
  • Sentinel Oncology
  • Serometrix
  • SGX Pharmaceuticals
  • Shenogen
  • Shire
  • Siena Biotech
  • Silence Therapeutics
  • Soligenix
  • Sophiris Bio
  • SRI International
  • Stainwei Biotech
  • Sunesis
  • Sunol Molecular
  • SuppreMol
  • Supratek Pharma
  • Swedish Orphan Biovitrum
  • Switch Pharma
  • Symphogen
  • Synageva BioPharma
  • SynerGene Therapeutics
  • Synta Pharmaceuticals
  • Taiho
  • Takeda
  • Tamir Biotechnology
  • Tapestry Pharmaceuticals
  • Targa Therapeutics
  • TargeGen
  • Tau Therapeutics
  • TauTaTis
  • TCD Pharma
  • TeGenero
  • Tekmira Pharmaceuticals
  • Telik
  • Teva
  • Thallion Pharmaceuticals
  • Therapure Biopharma
  • Therion Biologics
  • Theryte
  • ThromboGenics
  • Tigris Pharmaceuticals
  • Titan Pharmaceuticals
  • Tokai Pharmaceuticals
  • Tolerx
  • ToolGen
  • TopoTarget
  • Tracon Pharmaceuticals
  • Tragara Pharmaceuticals
  • Transgene
  • TransTech Pharma
  • Trillium Therapeutics
  • Trion Pharma
  • Twinstrand Therapeutics
  • UCB
  • Unigene
  • United Biomedical
  • United Therapeutics
  • Vaccinex
  • Wakunaga
  • VasGene Therapeutics
  • Vaxon Biotech
  • Velacor Therapeutics
  • Vernalis
  • Vertex Pharmaceuticals
  • Vical
  • Wilex
  • Vion Pharmaceuticals
  • VioQuest
  • Viragen
  • Viralytics
  • ViroMed
  • ViroTarg
  • Viventia Biotech
  • VM Discovery
  • Wyeth
  • XBiotech
  • Xcovery
  • Xencor
  • Xerion
  • Xoma
  • Y's Therapeutics
  • YM BioSciences
  • Zenotech
  • Zenyaku Kogyo
  • Zydus Cadila

A Shortlist of Drugs Included are:

  • 131I-tositumomab
  • abagovomab
  • abarelix
  • abiraterone acetate
  • AC-480
  • adecatumumab
  • aderbasib
  • AE-37
  • AEZS-108
  • AF-802
  • afatinib
  • aflibercept
  • alemtuzumab
  • ALT-801
  • alvocidib
  • AMG-386
  • amonafide dihydrochloride
  • amonafide malate
  • Angiozyme
  • apatinib
  • APC-100
  • APR-246
  • AR-42
  • ARC-100
  • ARQ-197
  • AT-7519
  • AT-9283
  • atrasentan
  • AVX-701
  • axitinib
  • AZD-8055
  • AZD-8931
  • bafetinib
  • barasertib
  • bardoxolone methyl
  • bevacizumab
  • BEZ-235
  • BGT-226
  • BI-811283
  • BIBF-1120
  • bicalutamide
  • BMS-690514
  • BMS-754807
  • BMS-777607
  • BMS-936558
  • bortezomib
  • bosutinib
  • BP-GMAX-CD1
  • brentuximab vedotin
  • brivanib alaninate
  • buserelin
  • Cabozantinib
  • CAL-101
  • carlumab
  • catumaxomab
  • CBP-501
  • CC-223
  • cediranib
  • celecoxib
  • cetuximab
  • cixutumumab
  • crizotinib
  • custirsen
  • dacomitinib
  • danusertib
  • dasatinib
  • DCVax-prostate
  • degarelix
  • denosumab
  • deslorelin
  • DI-17E6
  • dinaciclib
  • docetaxel
  • dovitinib lactate
  • doxercalciferol
  • doxorubicin
  • dutasteride
  • E-75
  • endoxifen
  • ENMD-2076
  • entinostat
  • enzastaurin hydrochloride
  • erlotinib
  • estramustine phosphate sodium
  • ethinyl estradiol sulfonate
  • everolimus
  • farletuzumab
  • figitumumab
  • flutamide
  • foretinib
  • fostamatinib disodium
  • fulvestrant
  • galiximab
  • gataparsen
  • GDC-0980
  • gefitinib
  • gemtuzumab ozogamicin
  • girentuximab
  • goserelin
  • GSK-2118436
  • GTx-758
  • GVAX
  • GVX-3322
  • GX-301
  • HE-3235
  • histrelin
  • ibritumomab tiuxetan
  • IC-83
  • icrucumab
  • idronoxil
  • imatinib mesilate
  • INCB-028060
  • inecalcitol
  • inotuzumab ozogamicin
  • INSM-18
  • interleukins
  • intetumumab
  • ipilimumab
  • irosustat
  • ispinesib mesylate
  • JI-101
  • KD032
  • KX2-391
  • lapatinib ditosylate
  • lenvatinib
  • lestaurtinib
  • leucine-doxorubicin
  • leuprolide
  • leuprolide acetate
  • leuprorelin
  • leuprorelin acetate
  • linifanib
  • linsitinib
  • LIP-131I
  • LipoVIL12
  • litronesib
  • LOR-2040
  • LOR-2501
  • lumiliximab
  • LY-2090314
  • LY-2275796
  • masitinib
  • MCS-110
  • MDV-3100
  • MGCD-265
  • midostaurin
  • MK-1775
  • MKC-1
  • MLN-8237
  • MM-111
  • motesanib diphosphate
  • MVA-BN Her-2 vaccine
  • Nab-docetaxel
  • nadroparin
  • naptumomab estafenatox
  • necitumumab
  • neratinib
  • nilotinib
  • nilutamide
  • nimotuzumab
  • NPB-001-056
  • obinutuzumab
  • oblimersen sodium
  • ofatumumab
  • OGX-427
  • olaparib
  • olaratumab
  • ON-01910
  • onartuzumab
  • oregovomab
  • orteronel
  • OSI-027
  • OTS-102
  • ozarelix
  • P276-00
  • paclitaxel
  • paclitaxel polyglumex
  • panitumumab
  • panobinostat
  • pazopanib hydrochloride
  • PD-0332991
  • pegdinetanib
  • perifosine
  • pertuzumab
  • PHA-848125AC
  • plitidepsin
  • PLX-3397
  • ponatinib
  • ProstAtak
  • PROSTVAC
  • PRX-302
  • PX-866
  • quarfloxacin
  • quinacrine
  • quizartinib dihydrochloride
  • R-(-)-gossypol
  • RAF-265
  • ramucirumab
  • Reditux
  • regorafenib
  • retaspimycin
  • ridaforolimus
  • rilotumumab
  • rituximab
  • romidepsin
  • ruxolitinib
  • RX-0201-N
  • sagopilone
  • sargramostim
  • SB-939
  • SCH-900776
  • seliciclib
  • siltuximab
  • sipuleucel-T
  • sirolimus
  • sorafenib tosylate
  • s-lapachone
  • SU-6668
  • sunitinib malate
  • TAK-448
  • talmapimod
  • tandutinib
  • tasquinimod
  • telatinib
  • temsirolimus
  • Tenarad
  • terameprocol
  • tivozanib
  • TOK-001
  • toremifene citrate
  • trastuzumab
  • TRC-105
  • tremelimumab
  • triciribine phosphate
  • trilostane
  • triptorelin
  • TroVax
  • TS-1
  • tucotuzumab celmoleukin
  • vandetanib
  • varlitinib
  • vemurafenib
  • volasertib
  • vosaroxin
  • XL-147
  • XL-281
  • XL-413
  • XL-647
  • XL-765
  • YM-155
  • zalutumumab
  • zanolimumab
  • zibotentan
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