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Triple Analysis: Pancreatic Cancer, Cancer Vaccines and Protein Kinase Inhibitors

Abstract

This triple analysis focuses on cancer drug development strategies in Pancreatic Cancer and by the two mechanism/target/effect areas of Cancer Vaccines and Protein Kinase Inhibitors. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.

Table of Contents

Key Topics Covered:

Part I: Pancreatic Cancer

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target Among Pancreatic Cancer Drugs for the Highest Therapeutic Outcome and Return on Investment (197 Drug Targets)
  • 7. Emerging New Products to Established Ones: Drug Target Strategies of Pancreatic Cancer Drugs by their Highest Stage of Development (163 Drug Target Strategies and 247 Drugs)
  • 8. Compound Strategies at Work: Competitive Benchmarking of Pancreatic Cancer Drugs by Compound Strategy (8 Compound Strategies)
  • 9. Pipeline and Portfolio Planning: Competitive Benchmarking of the Pancreatic Cancer Drug Pipeline by Investigator (158 Investigators and 247 Drugs)
  • 10. Drug Index
  • 11. Company Index
  • Figures: Includes 7 Figures
  • Tables: Includes 218 Tables
  • Total Number of Pages: 1,103

Part II: Cancer Vaccines

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target Among Cancer Vaccine Drugs for the Highest Therapeutic Outcome and Return on Investment (94 Drug Targets)
  • 7. Emerging New Products to Established Ones: Drug Target Strategies of Cancer Vaccine Drugs by their Highest Stage of Development (91 Drug Target Strategies and 155 Cancer Vaccine Drugs)
  • 8. Compound Strategies at Work: Competitive Benchmarking of Cancer Vaccine Drugs by Compound Strategy (7 Compound Strategies)
  • 9. Selecting Cancer Indications for Cancer Vaccine Drugs (42 Cancer Indications)
  • 10. Pipeline and Portfolio Planning: Competitive Benchmarking of the Cancer Vaccine Drug Pipeline by Investigator (99 Investigators)
  • 11. Disclaimer
  • 12. Drug Index
  • 13. Company Index
  • Figures: Includes 6 Figures
  • Tables: Includes 205 Tables
  • Total Number of Pages: 659

Part III: Protein Kinase Inhibitors

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (133 Drug Targets)
  • 7. The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Profiles Identified in the Cancer Protein Kinase Therapeutic Pipeline? (200 Drug Target Strategies and 409 Drugs)
  • 8. Compound Strategies at Work: Competitive Benchmarking of Protein Kinase Drugs in Oncology by Compound Type (7 Compound Strategies)
  • 9. Selecting Cancer Indications for Protein Kinase Therapeutics (57 Different Cancer Indications)
  • 10. Portfolio Planning: Competitive Benchmarking of Protein Kinase Cancer Therapeutic Pipeline by Investigator (160 Investigators)
  • 12. Drug Index
  • 13. Company Index
  • Figures: Includes 6 Figures
  • Tables: Includes 302 Tables
  • Total Number of Pages: 1442

This Report Includes the Following Companies:

  • 4SC
  • AB Science
  • Abbott
  • Abiogen
  • Abraxis BioScience
  • AC Immune
  • Active Biotech
  • Adaptimmune
  • Aduro BioTech
  • Advantagene
  • Advaxis
  • Advenchen
  • AEgera
  • AEterna Zentaris
  • Aida Pharmaceuticals
  • Akela Pharma
  • Alethia Biotherapeutics
  • Alfacell
  • AlphaVax
  • Ambit Biosciences
  • Amgen
  • Amphora
  • Antisense Pharma
  • Anza Therapeutics
  • Apogee Biotechnology
  • Apotex
  • Apthera
  • Ardea Biosciences
  • Ariad
  • Arno Therapeutics
  • ArQule
  • Array BioPharma
  • Astellas
  • Astex Therapeutics
  • AstraZeneca
  • AVEO
  • AVI BioPharma
  • Bavarian Nordic
  • Bayer
  • Bellicum Pharmaceuticals
  • Benitec
  • Berkeley Lab
  • Betapharma
  • BioAxone
  • Biogen Idec
  • Bionovo
  • BioNumerik
  • BioSante
  • Biostar
  • Biotecnol
  • BioVex
  • Boehringer Ingelheim
  • Bristol-Myers Squibb
  • BTG
  • Cadila
  • Calando Pharmaceuticals
  • Callisto Pharmaceuticals
  • CanBas
  • Cancer Advances
  • Cancer Research Technology
  • Celera
  • Celgene
  • Cell Genesys
  • Cell Therapeutics
  • Celldex Therapeutics
  • Celsion
  • Celtic Pharma
  • Center of Molecular Immunology
  • Cephalon
  • CG Therapeutics
  • Chroma Therapeutics
  • CompleGen
  • Compugen
  • Cornerstone Pharmaceuticals
  • Cosmo Pharmaceuticals
  • CritiTech
  • CSL
  • Curaxis
  • Curis
  • Cyclacel
  • Cylene Pharmaceuticals
  • Cynvec
  • CytImmune Sciences
  • Cytokinetics
  • CytRx
  • Daiichi Sankyo
  • Dainippon Sumitomo Pharma
  • Dara Biosciences
  • Deciphera Pharmaceuticals
  • Dendreon
  • DeveloGen
  • Dyax
  • EGEN Inc
  • Eisai
  • Elara Pharmaceuticals
  • Eli Lilly
  • Enkam Pharmaceuticals
  • EntreMed
  • Epeius Biotechnologies
  • EpiCept
  • Esperance Pharmaceuticals
  • Exelixis
  • FibroGen
  • Galapagos
  • Galectin Therapeutics
  • Genentech
  • Generex
  • GenOdyssee Pharmaceuticals
  • Genta
  • GENTICEL
  • GenVec
  • Geron
  • GlaxoSmithKline
  • Gliknik
  • GlobeImmune
  • GlycoGenesys
  • GPC Biotech
  • Gradalis
  • Hanmi
  • Hoffmann-La Roche
  • Human Genome Sciences
  • Ichor Medical Systems
  • Idera Pharmaceuticals
  • ImClone Systems
  • ImmunoCellular Therapeutics
  • ImmunoFrontier
  • ImmunoGen
  • Immunomedics
  • Immunotope
  • ImmuPharma
  • Immutep
  • Incyte Corporation
  • Innate Pharma
  • Innovive
  • Inovio
  • Insmed
  • Insys Therapeutics
  • Introgen Therapeutics
  • Ipsen
  • ISA Pharmaceuticals
  • ISU ABXIS
  • Johnson & Johnson
  • Kadmon
  • KAI Pharmaceuticals
  • Kalypsys
  • Keryx Biopharmaceuticals
  • Kiadis
  • Kirin Pharma
  • Kyowa Hakko Kirin
  • Leo
  • Locus Pharmaceuticals
  • Lorus Therapeutics
  • MaxoCore Pharmaceuticals
  • MBiotec
  • Meda
  • Medical Marketing International
  • MediGene
  • Medisyn Technologies
  • Menarini
  • Merck & Co
  • Merck KGaA
  • Merrimack
  • Mersana Therapeutics
  • MethylGene
  • Micromet
  • Mitsubishi Tanabe Pharma
  • MolMed
  • Mologen
  • Nektar Therapeutics
  • Nemod Biotherapeutics
  • NeoPharm
  • Neovacs
  • Nereus Pharmaceuticals
  • Nerviano Medical Sciences
  • NicOx
  • Nidus Laboratories
  • NIH
  • Nippon Kayaku
  • Nippon Shinyaku
  • Non-industrial source
  • Northwest Biotherapeutics
  • Novacea
  • NovaLead
  • Novartis
  • NovaRx
  • Novogen
  • Oncalis
  • OncoMed
  • OncoMune
  • Onconova
  • OncoTherapy Science
  • Oncothyreon
  • Oncovir
  • Oncozyme Pharma
  • Onyvax
  • OSI Pharmaceuticals
  • Oxford BioMedica
  • OXiGENE
  • Paladin Labs
  • PanaGin
  • Patrys
  • Pepscan Systems
  • Pepscan Therapeutics
  • Peregrine Pharmaceuticals
  • Pfizer
  • Pharmacyclics
  • PharmaGap
  • PharmaMar
  • Pharmexa
  • Pierre Fabre
  • Piramal
  • Plexxikon
  • Prima Biomed
  • Progenics Pharmaceuticals
  • ProMetic Life Sciences
  • Protgen
  • Protherics
  • QLT
  • Radient Pharmaceuticals
  • Ras Therapeutics
  • Reata Pharmaceuticals
  • Receptor BioLogix
  • Regeneron
  • Regulon
  • responsif
  • RESprotect
  • Rexahn
  • Rigel
  • Rottapharm Madaus
  • Samyang
  • Sanofi
  • Sanofi-Aventis
  • Santaris Pharma
  • Sareum
  • SBIO
  • Scancell
  • Schering-Plough
  • SciClone Pharmaceuticals
  • Semafore Pharmaceuticals
  • Shire
  • Silence Therapeutics
  • SuperGen
  • Supratek Pharma
  • Switch Pharma
  • Taiho
  • Takeda
  • Talon Therapeutics
  • Tapestry Pharmaceuticals
  • TapImmune
  • Targa Therapeutics
  • TargeGen
  • Tau Therapeutics
  • Tekmira Pharmaceuticals
  • Telik
  • Teva
  • Thallion Pharmaceuticals
  • Therion Biologics
  • Theryte
  • Titan Pharmaceuticals
  • ToolGen
  • TopoTarget
  • Tragara Pharmaceuticals
  • Transgene
  • Trion Pharma
  • UCB
  • UMN Pharma
  • United Biomedical
  • Vaccinex
  • VasGene Therapeutics
  • Vaxil BioTherapeutics
  • Vaxon Biotech
  • VaxOnco
  • Vectura
  • Velacor Therapeutics
  • Vertex Pharmaceuticals
  • Vical
  • Wilex
  • Vion Pharmaceuticals
  • VioQuest
  • Viragen
  • Virionics
  • ViroMed
  • Wyeth
  • Xencor
  • Xerion
  • Yakult Honsha
  • YM BioSciences
  • Zensun
  • Zeria

A Shortlist of Drugs Included are:

  • ADXS11-001
  • AE-37
  • AEG-35156
  • aflibercept
  • AGS-1C4D4
  • ALVAC-CEA/B7.1
  • alvocidib
  • apricoxib
  • ARC-100
  • ARQ-197
  • astuprotimut-r
  • AVX-701
  • axitinib
  • bardoxolone methyl
  • belagenpumatucel-L
  • bevacizumab
  • BIBW-2992
  • bosutinib
  • BP-GMAX-CD1
  • brivanib alaninate
  • brivudine
  • Cabozantinib
  • Cadi-05
  • capecitabine
  • catumaxomab
  • CB-10-01
  • CEA-TRICOM
  • cediranib
  • celecoxib
  • cetuximab
  • CG-201
  • cilengitide
  • cixutumumab
  • CMLVAX-100
  • conatumumab
  • CPI-613
  • CRLX-101
  • CTL901
  • CTP-37
  • CVac
  • dalotuzumab
  • dasatinib
  • DCVax-prostate
  • deforolimus
  • docetaxel
  • doxorubicin
  • E-75
  • E-7820
  • eniluracil
  • enzastaurin hydrochloride
  • erlotinib
  • everolimus
  • fowlpox-PSA vaccine
  • ganitumab
  • gefitinib
  • GRNVAC1
  • GSK-1120212
  • GV-1001
  • GV-1002
  • GVAX
  • GVX-3322
  • Her-2/Neu peptides
  • icotinib hydrochloride
  • idronoxil
  • IGN-101
  • imatinib mesilate
  • ImmunoVEX tri-melan
  • IMO-2055
  • IMP-321
  • INGN-225
  • ipilimumab
  • irinotecan
  • irinotecan hydrochloride
  • KD032
  • L19-IL2
  • lapatinib ditosylate
  • lestaurtinib
  • LipoVIL12
  • MAGE-3-TK
  • masitinib
  • ME-103
  • MetXia
  • MGN-1601
  • midostaurin
  • MKC-1
  • mocetinostat
  • motesanib diphosphate
  • motexafin gadolinium
  • MSI vaccine
  • MVA-BN
  • MVA-BN Her-2 vaccine
  • nadroparin
  • nilotinib
  • nimotuzumab
  • Norelin
  • oblimersen sodium
  • olaparib
  • Onyvax-105
  • OTS-102
  • P-276-00
  • paclitaxel
  • PancAtak
  • panobinostat
  • PANVAC-VF
  • pasireotide
  • pasireotide LAR
  • pazopanib hydrochloride
  • PCI-27483
  • pDOM-PSMA27
  • pemetrexed disodium
  • pentamidine isethionate
  • PEP-223
  • perifosine
  • plitidepsin
  • poly-ICLC
  • PR1:169-177 peptide
  • PROSTVAC
  • PX-104.1
  • PX-12
  • ramucirumab
  • Reximmune-C
  • Rexin-G
  • rindopepimut
  • romidepsin
  • RX-0201
  • SAI-EGF
  • selumetinib
  • siltuximab
  • sorafenib tosylate
  • s-lapachone
  • Stimuvax
  • sunitinib malate
  • talminogene laherparepvec
  • tanespimycin
  • tegafur + uracil
  • temsirolimus
  • TG-4001
  • TG-4010
  • thymalfasin
  • tigatuzumab
  • tocilizumab
  • trabedersen
  • trastuzumab
  • triciribine phosphate
  • TroVax
  • TS-1
  • tucotuzumab celmoleukin
  • vandetanib
  • varlitinib
  • verpasep caltespen
  • vismodegib
  • volociximab
  • VX-001
  • WX-671
  • XL-184
  • Z-360
  • ZYC-300
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