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Triple Analysis: Melanoma, Prostate Cancer and Cancer Vaccines

Abstract

This triple analysis focuses on cancer drug development strategies in both Melanoma and Prostate Cancer and by the mechanism/target/effect of Cancer Vaccines. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.

Table of Contents

Key Topics Covered:

Part I: Melanoma

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target Among Melanoma Drugs for the Highest Therapeutic Outcome and Return on Investment (170 Drug Targets)
  • 7. Emerging New Products to Established Ones: Drug Target Strategies of Melanoma Drugs by their Highest Stage of Development (151 Drug Target Strategies and 218 Melanoma Drugs)
  • 8. Compound Strategies at Work: Competitive Benchmarking of Melanoma Drugs by Compound Strategy (8 Compound Strategies)
  • 9. Pipeline and Portfolio Planning: Competitive Benchmarking of the Melanoma Drug Pipeline by Investigator (138 Companies)
  • 10. Disclaimer
  • 11. Drug Index
  • 12. Company Index
  • Figures: Includes 6 Figures
  • Tables: Includes 196 Tables
  • Total Number of Pages: 777

Part II: Prostate Cancer

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target Among Prostate Cancer Drugs for the Highest Therapeutic Outcome and Return on Investment (227 Drug Targets)
  • 7. Emerging New Products to Established Ones: Drug Target Strategies of Prostate Cancer Drugs by their Highest Stage of Development (216 Drug Target Strategies and 394 Drugs)
  • 8. Compound Strategies at Work: Competitive Benchmarking of Prostate Cancer Drugs by Compound Strategy (8 Compound Strategies)
  • 9. Pipeline and Portfolio Planning: Competitive Benchmarking of the Prostate Cancer Drug Pipeline by Investigator (222 Investigators and 394 Drugs)
  • 10. Disclaimer
  • Figures: Includes 8 Figures
  • Tables: Includes 283 Tables
  • Total Number of Pages: 1,493

Part III: Cancer Vaccines

  • 5.1. The Scope of this Report
  • 6. Consider the Therapeutic Target Among Cancer Vaccine Drugs for the Highest Therapeutic Outcome and Return on Investment (94 Drug Targets)
  • 7. Emerging New Products to Established Ones: Drug Target Strategies of Cancer Vaccine Drugs by their Highest Stage of Development (91 Drug Target Strategies and 155 Cancer Vaccine Drugs)
  • 8. Compound Strategies at Work: Competitive Benchmarking of Cancer Vaccine Drugs by Compound Strategy (7 Compound Strategies)
  • 9. Selecting Cancer Indications for Cancer Vaccine Drugs (42 Cancer Indications)
  • 10. Pipeline and Portfolio Planning: Competitive Benchmarking of the Cancer Vaccine Drug Pipeline by Investigator (99 Investigators)
  • 11. Disclaimer
  • 12. Drug Index
  • 13. Company Index
  • Figures: Includes 6 Figures
  • Tables: Includes 205 Tables
  • Total Number of Pages: 659

This Report Includes the Following Companies:

  • 3SBio
  • Abbott
  • Abiogen
  • Abraxis BioScience
  • AC Immune
  • Actelion
  • Active Biotech
  • Adaptimmune
  • Adherex
  • Aduro BioTech
  • Advanced Life Sciences
  • Advantagene
  • Advaxis
  • AEgera
  • AEterna Zentaris
  • Aida Pharmaceuticals
  • Akela Pharma
  • Alchemia
  • Alethia Biotherapeutics
  • Allos Therapeutics
  • Alnylam
  • AlphaVax
  • Alseres Pharmaceuticals
  • Altor BioScience
  • Ambit Biosciences
  • Ambrilia Biopharma
  • American Gene Technology International
  • Amgen
  • Anavex Life Sciences
  • AndroBioSys
  • AngioChem
  • Antisense Pharma
  • Antisense Therapeutics
  • Antisoma
  • Aphios
  • ApopLogic Pharmaceuticals
  • Apotex
  • Aprea
  • Apthera
  • Ardana
  • Ariad
  • ArQule
  • Array BioPharma
  • Ascenta Therapeutics
  • Ascepion Pharmaceuticals
  • Astellas
  • Astex Pharmaceuticals
  • Astex Therapeutics
  • AstraZeneca
  • Attenuon
  • AVI BioPharma
  • Bavarian Nordic
  • Baxter International
  • Bayer
  • Bellicum Pharmaceuticals
  • Bio-Medisinsk Innovasjon
  • BioAlliance Pharma
  • Bioenvision
  • Biogen Idec
  • Biokine Therapeutics
  • BioLineRx
  • BioMarin
  • BioNetWorks
  • BioNumerik
  • BioSante
  • Biosceptre
  • Biostar
  • Biotecnol
  • BioVex
  • Boehringer Ingelheim
  • Bristol-Myers Squibb
  • BTG
  • Cadila
  • Camurus
  • Cancer Research Technology
  • CDG Therapeutics
  • Cel-Sci
  • Celgene
  • Cell Genesys
  • Cell Therapeutics
  • Celldex Therapeutics
  • Celsion
  • Celtic Pharma
  • Center of Molecular Immunology
  • Cephalon
  • CG Therapeutics
  • Chemokine Therapeutics
  • Circadian Technologies
  • CJ Corp
  • Clavis Pharma
  • Cleveland BioLabs
  • Colby
  • Cosmo Bioscience
  • Cosmo Pharmaceuticals
  • CSL
  • Curaxis
  • Curis
  • Cylene Pharmaceuticals
  • CytImmune Sciences
  • Cytokinetics
  • Daewoong
  • Daiichi Sankyo
  • Dara Biosciences
  • Debiopharm
  • Deciphera Pharmaceuticals
  • Dendreon
  • DeveloGen
  • DNAVEC
  • Dong-A
  • Dongkook Pharm
  • ECI
  • Eisai
  • Eli Lilly
  • Endo Pharmaceuticals
  • Endocyte
  • Ensemble Discovery
  • EntreMed
  • Enzon
  • Epeius Biotechnologies
  • EpiCept
  • Esperance Pharmaceuticals
  • Etubics
  • EUSA Pharma
  • Exelixis
  • Facet Biotech
  • Ferring
  • Flamel Technologies
  • Formula Pharmaceuticals
  • Galena Biopharma
  • Gemin X Pharmaceuticals
  • Generex
  • GenOdyssee Pharmaceuticals
  • GENova Biotherapeutics
  • Genovax
  • Genta
  • GENTICEL
  • GenVec
  • Genzyme
  • Gerolymatos
  • Geron
  • Gilead Sciences
  • GlaxoSmithKline
  • Gliknik
  • GlobeImmune
  • GlycoGenesys
  • Got-a-Gene
  • GP Pharm
  • Gradalis
  • Green Cross
  • GTx
  • Harbor BioSciences
  • Hemispherx Biopharma
  • Hoffmann-La Roche
  • Human Genome Sciences
  • Ichor Medical Systems
  • Idera Pharmaceuticals
  • IGF Oncology
  • ImmunoCellular Therapeutics
  • Immunocore
  • ImmunoFrontier
  • ImmunoGen
  • Immunomedics
  • Immunotope
  • ImmuPharma
  • Immutep
  • Incyte Corporation
  • Infinity Pharmaceuticals
  • Innate Pharma
  • Inotek
  • Inovio
  • Insmed
  • Insys Therapeutics
  • Intrexon
  • Introgen Therapeutics
  • Ipsen
  • ISA Pharmaceuticals
  • Isis Pharmaceuticals
  • Ivy Medical Chemicals
  • Jennerex Biotherapeutics
  • Johnson & Johnson
  • Kalypsys
  • Karo Bio
  • Karyon-CTT
  • Kiadis
  • Kinex
  • Kyowa Hakko Kirin
  • Leo
  • LG Life Sciences
  • Ligand
  • Lorus Therapeutics
  • Mannkind
  • Marillion Pharmaceuticals
  • Med Discovery
  • Meda
  • Medarex
  • Medical Marketing International
  • MediGene
  • MedImmune
  • Mediolanum
  • Medisyn Technologies
  • Medivation
  • Menarini
  • Merck & Co
  • Merck KGaA
  • Merrion Pharmaceuticals
  • MethylGene
  • Micromet
  • Mitsubishi Tanabe Pharma
  • Mochida
  • Mojave Therapeutics
  • Molecular Insight
  • MolMed
  • Mologen
  • Nektar Therapeutics
  • Nemod Biotherapeutics
  • Neovacs
  • Nereus Pharmaceuticals
  • Nerviano Medical Sciences
  • Neurocrine Biosciences
  • Nippon Shinyaku
  • Non-industrial source
  • Northwest Biotherapeutics
  • Novacea
  • Novartis
  • NovaRx
  • Novogen
  • Oasmia
  • Oncalis
  • OncoGenex Pharmaceuticals
  • OncoMune
  • OncoTherapy Science
  • Oncothyreon
  • Oncovir
  • Onyvax
  • Orion Pharma
  • OSI Pharmaceuticals
  • Oxford BioMedica
  • Paladin Labs
  • Pantarhei Bioscience
  • PBL Therapeutics
  • Pepscan Systems
  • Pepscan Therapeutics
  • Pfizer
  • Pharmacyclics
  • PharmaGap
  • PharmaMar
  • Pharmexa
  • Philogen
  • PhiloGene
  • Pierre Fabre
  • Piramal
  • Plexxikon
  • Prima Biomed
  • Progen
  • Progenics Pharmaceuticals
  • ProNAi Therapeutics
  • ProStrakan
  • Protherics
  • Q Chip
  • QLT
  • Radient Pharmaceuticals
  • Reata Pharmaceuticals
  • Receptor BioLogix
  • Regeneron
  • Regulon
  • responsif
  • Rexahn
  • Salzburg Therapeutics
  • Samyang
  • Sanofi
  • Sanofi-Aventis
  • Santaris Pharma
  • Sapphire Therapeutics
  • Sareum
  • SBIO
  • Scancell
  • SciClone Pharmaceuticals
  • Seattle Genetics
  • SeleXel
  • Semafore Pharmaceuticals
  • Serometrix
  • SGX Pharmaceuticals
  • Shire
  • Siena Biotech
  • Simcere Pharmaceuticals
  • Solbec Pharmaceuticals
  • Soligenix
  • Sophiris Bio
  • Spirogen
  • SRI International
  • SuperGen
  • Supratek Pharma
  • Swedish Orphan Biovitrum
  • Switch Pharma
  • Synta Pharmaceuticals
  • Taiho
  • Takeda
  • Tapestry Pharmaceuticals
  • TapImmune
  • Targa Therapeutics
  • Targepeutics
  • Tau Therapeutics
  • Teva
  • Thallion Pharmaceuticals
  • Therion Biologics
  • Titan Pharmaceuticals
  • Tokai Pharmaceuticals
  • TopoTarget
  • Tracon Pharmaceuticals
  • Transgene
  • Twinstrand Therapeutics
  • Unigene
  • United Biomedical
  • Vaccinex
  • Vaxil BioTherapeutics
  • Vaxon Biotech
  • VaxOnco
  • VBL Therapeutics
  • Vectura
  • Velacor Therapeutics
  • Vical
  • Wilex
  • Vion Pharmaceuticals
  • VioQuest
  • Viragen
  • Viralytics
  • Virionics
  • ViroMed
  • ViroTarg
  • VM Discovery
  • Xerion
  • Xoma
  • YM BioSciences
  • York Pharma
  • Zensun
  • Zydus Cadila
  • ZymoGenetics

A Shortlist of Drugs Included are:

  • abarelix
  • abiraterone acetate
  • adecatumumab
  • aderbasib
  • ADXS11-001
  • AE-37
  • AEZS-108
  • afatinib
  • aflibercept
  • AG-14699
  • agatolimod
  • aldesleukin
  • ALT-801
  • ALVAC-CEA/B7.1
  • alvocidib
  • amonafide dihydrochloride
  • amonafide malate
  • APC-100
  • APO-866
  • APR-246
  • ARC-100
  • astuprotimut-r
  • atrasentan
  • AVX-701
  • axitinib
  • bafetinib
  • bardoxolone methyl
  • belagenpumatucel-L
  • belinostat
  • bevacizumab
  • BIBF-1120
  • bicalutamide
  • BMS-663513
  • BMS-777607
  • BMS-936558
  • bortezomib
  • bosentan
  • BP-GMAX-CD1
  • buserelin
  • Cabozantinib
  • Cadi-05
  • carlumab
  • CB-10-01
  • CEA-TRICOM
  • cediranib
  • celecoxib
  • cetuximab
  • CG-201
  • cixutumumab
  • CMLVAX-100
  • cositecan
  • CTL901
  • CTP-37
  • custirsen
  • CVac
  • danusertib
  • dasatinib
  • DCVax-prostate
  • decitabine
  • degarelix
  • denenicokin
  • denosumab
  • deslorelin
  • DI-17E6
  • docetaxel
  • dovitinib lactate
  • doxercalciferol
  • doxorubicin
  • dutasteride
  • E-75
  • EMD-273063
  • endostatin
  • entinostat
  • enzastaurin hydrochloride
  • epirubicin
  • estramustine phosphate sodium
  • ethinyl estradiol sulfonate
  • everolimus
  • Exherin
  • figitumumab
  • flutamide
  • fowlpox-PSA vaccine
  • fresolimumab
  • fulvestrant
  • gataparsen
  • GDC-0980
  • gefitinib
  • glembatumumab
  • golnerminogene pradenovec
  • goserelin
  • GRNVAC1
  • GT-111
  • GTx-758
  • GV-1001
  • GV-1002
  • GVAX
  • GVX-3322
  • GX-301
  • HE-3235
  • Her-2/Neu peptides
  • histamine dihydrochloride
  • histrelin
  • idronoxil
  • IGN-101
  • imatinib mesilate
  • ImmunoVEX tri-melan
  • IMO-2055
  • IMP-321
  • inecalcitol
  • INGN-225
  • INGN-241
  • INSM-18
  • interferon-alpha
  • interferon-alpha2
  • interferon-alpha2a
  • interferon-alpha2b
  • interferon-beta
  • interleukin-2, 2nd-generation
  • interleukins
  • intetumumab
  • IPH-1101
  • ipilimumab
  • irosustat
  • ispinesib mesylate
  • JX-594
  • kahalalide F
  • KX2-391
  • L19-IL2
  • lapatinib ditosylate
  • lestaurtinib
  • leucine-doxorubicin
  • leuprolide
  • leuprolide acetate
  • leuprorelin
  • leuprorelin acetate
  • LIP-131I
  • LipoVIL12
  • litronesib
  • LOR-2040
  • LOR-2501
  • LY-2275796
  • MAGE-3-TK
  • MCS-110
  • MDV-3100
  • MDX-1106
  • ME-103
  • MetXia
  • MGN-1601
  • MKC-1106-MT
  • MLN-8237
  • MSI vaccine
  • MVA-BN
  • MVA-BN Her-2 vaccine
  • Nab-docetaxel
  • nadroparin
  • nilutamide
  • nimotuzumab
  • Norelin
  • oblimersen sodium
  • OGX-427
  • olaparib
  • olaratumab
  • OncoVEX GM-CSF
  • Onyvax-105
  • orteronel
  • OTS-102
  • ozarelix
  • P-276-00
  • paclitaxel
  • paclitaxel polyglumex
  • panitumumab
  • panobinostat
  • PANVAC-VF
  • pDOM-PSMA27
  • peginterferon alfa-2b
  • PEP-223
  • perifosine
  • pertuzumab
  • plitidepsin
  • PLX-3397
  • PLX-4032
  • poly-ICLC
  • PR1:169-177 peptide
  • ProstAtak
  • PROSTVAC
  • PRX-302
  • PX-104.1
  • PX-866
  • quarfloxacin
  • quinacrine
  • R-(-)-gossypol
  • ramucirumab
  • retaspimycin
  • Reximmune-C
  • ridaforolimus
  • rilotumumab
  • rindopepimut
  • romidepsin
  • ruxolitinib
  • sagopilone
  • SAI-EGF
  • sargramostim
  • SB-939
  • selumetinib
  • siltuximab
  • sipuleucel-T
  • sodium stibogluconate
  • sorafenib tosylate
  • Stimuvax
  • sunitinib malate
  • TAK-448
  • tandutinib
  • tasquinimod
  • temsirolimus
  • Tenarad
  • TG-4001
  • TG-4010
  • thymalfasin
  • TOK-001
  • topotecan
  • toremifene citrate
  • trabedersen
  • TRC-105
  • tremelimumab
  • trilostane
  • triptorelin
  • TroVax
  • TS-1
  • tucotuzumab celmoleukin
  • vandetanib
  • velimogene aliplasmid
  • veliparib
  • verpasep caltespen
  • volociximab
  • VX-001
  • YM-155
  • zibotentan
  • ZYC-300
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