Market Research Report

Product Profiles: Schizophrenia - Adjunctive treatments to carve new niche in mature market

cover Published by Datamonitor
Published Product code 229416
Content info Pages: 193
Price

Introduction

Description

Introduction

With the imminent loss of market exclusivity of key atypical antipsychotics Zyprexa (olanzapine; Eli Lilly) and Seroquel (quetiapine: AstraZeneca), schizophrenia pipeline therapies will launch into a competitive market. Datamonitor views the development of novel drugs and adjunctive therapies as an important strategy for success.

Features and benefits

  • Access Datamonitor's assessment of key marketed and pipeline drugs' clinical and commercial attractiveness.
  • Assessment of the strengths, weaknesses, opportunities and threats for marketed and late-stage pipeline candidates
  • Analysis of the product positioning for each marketed agents within the schizophrenia market.
  • Evaluate the latest clinical trial data for late-stage pipeline drugs and how they satisfy the unmet needs in schizophrenia

Highlights

  • In order to thrive in the schizophrenia environment, new therapies must be sufficiently differentiated from existing antipsychotics. Datamonitor believes developers of undifferentiated oral products will struggle to compete in this mature market because but will find position as second or later line of therapy for treatment refractory patients
  • Developing depot formulations is a key successful life-cycle management strategy in the schizophrenia market in order to protect franchises from generic erosion. Recent launches of monthly depots Zyprexa Relprevv and Invega Sustenna have helped Eli Lilly and Johnson & Johnson strengthen their position in this market.
  • The prospects for adjunctive therapies for hard-to-treat schizophrenia symptoms will be highly welcomed and will create a new niche in this mature market. Rather than compete with existing therapies, these drugs will complement generic formulations to partially combat generic erosion.

Your key questions answered

  • Where will new adjunctive therapies be positioned?
  • What strategies will developers implement upon generic erosion of their brands?
  • Where will the new pipeline therapies fit into the treatment algorithm?
  • What are the comparative strengths and weaknesses of the key schizophrenia brands and how do they compare to and pipeline candidates?

Table of Contents

TOC

Executive Summary

  • Strategic scoping and focus
  • Datamonitor key findings

OVERVIEW

  • Catalyst
  • Summary

MARKET DEFINITION AND OVERVIEW

  • Product overview

MARKETED PRODUCT PROFILES

  • Zyprexa/Zyprexa Relprevv (olanzapine; Eli Lilly)
    • Drug overview
    • Development overview
    • SWOT analysis
    • Product positioning
    • Clinical and commercial attractiveness
  • Abilify (aripiprazole; Bristol-Myers Squibb/Otsuka Pharmaceuticals)
    • Drug overview
    • Development overview
    • SWOT analysis
    • Product positioning
    • Clinical and commercial attractiveness
  • Seroquel/Seroquel XR (quetiapine; AstraZeneca)
    • Drug overview
    • Development overview
    • SWOT analysis
    • Product positioning
    • Clinical and commercial attractiveness
  • Latuda (lurasidone; Sunovion Pharmaceuticals/Dainippon Sumitomo/Takeda)
    • Drug overview
    • Development overview
    • SWOT analysis
    • Product positioning
    • Clinical and commercial attractiveness
  • Invega/Invega Sustenna (paliperidone; Johnson & Johnson)
    • Drug overview
    • Development overview
    • SWOT analysis
    • Product positioning
    • Clinical and commercial attractiveness
  • Saphris (asenapine; Merck & Co.)
    • Drug overview
    • Development overview
    • SWOT analysis
    • Product positioning
    • Clinical and commercial attractiveness
  • Fanapt (iloperidone; Novartis/Vanda)
    • Drug overview
    • Development overview
    • SWOT analysis
    • Product positioning
    • Clinical and commercial attractiveness
  • Risperdal/Risperdal Consta (risperidone; Johnson & Johnson)
    • Drug overview
    • Development overview
    • SWOT analysis
    • Product positioning
    • Clinical and commercial attractiveness
  • Geodon (ziprasidone; Pfizer)
    • Drug overview
    • Developmental overview
    • SWOT analysis
    • Product positioning
    • Clinical and commercial attractiveness
  • Other marketed drugs for schizophrenia
    • Clozaril/Leponex (clozapine; Novartis)
    • Lonasen (blonanserin; Dainippon Sumitomo)

PIPELINE PRODUCT PROFILES: MONOTHERAPIES

  • Abilify depot (aripiprazole long-acting injection; Bristol-Myers Squibb/Otsuka Pharmaceuticals)
    • Drug overview
    • Development overview
    • Product positioning
    • SWOT analysis
    • Satisfaction of unmet needs
    • Clinical and commercial attractiveness
  • Adasuve (Staccato loxapine; Alexza Pharmaceuticals)
    • Drug profile
    • Development overview
    • Satisfaction of unmet needs
    • SWOT analysis
    • Clinical and commercial attractiveness
  • Cariprazine (Forest Laboratories/Mitsubishi Tanabe/Gedeon Richter)
    • Drug overview
    • Development overview
    • Satisfaction of unmet needs
    • SWOT analysis
    • Clinical and commercial attractiveness
  • LY2140023 (Eli Lilly)
    • Drug overview
    • Development overview
    • Satisfaction of unmet needs
    • SWOT analysis
    • Clinical and commercial attractiveness
  • Zicronapine (Lu 31-130; Lundbeck)
    • Drug overview
    • Development overview
    • Satisfaction of unmet needs
    • SWOT analysis
    • Clinical and commercial attractiveness
  • Other monotherapies in development
    • OPC-34712 (Otsuka)

PIPELINE PRODUCT PROFILES: ADJUNCTIVE THERAPIES

  • RG1678 (RO4917838; Roche/Chugai)
    • Drug profile
    • Development overview
    • Satisfaction of unmet needs
    • SWOT analysis
    • Clinical and commercial attractiveness
  • Vyvanse (lisdexamfetamine; Shire)
    • Drug profile
    • Development overview
    • Satisfaction of unmet needs
    • SWOT analysis
    • Clinical and commercial attractiveness
  • Pimavanserin tartrate (ACP-103; Acadia Pharmaceuticals)
    • Drug overview
    • Development overview
    • Satisfaction of unmet needs
    • SWOT analysis
    • Clinical and commercial attractiveness
  • BL-1020 (formerly CYP-1020; BioLineRx)
    • Drug overview
    • Development overview
    • Satisfaction of unmet needs
    • SWOT analysis
    • Clinical and commercial attractiveness
  • Othe

Product Profiles: Schizophrenia - Adjunctive treatments to carve new niche in mature market published by Datamonitor in October 14, 2011. This report consists of Pages: 193 and the price starts from US $ 11400.

Back to Top