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Epidemiology: Trigeminal Neuralgia - The disease is not as rare as previously thought

Abstract

Introduction

This module provides an estimate of the number of diagnosed incident and total prevalent cases of trigeminal neuralgia in the seven major markets using historical trends for the disease and underlying risk factors.

Features and benefits

  • Gain insight into market potential, including a robust 10-year epidemiology forecast of trigeminal neuralgia incident and total prevalent cases.
  • Understand the key epidemiologic risk factors associated with trigeminal neuralgia.

Highlights

Datamonitor expects to see few diagnosed incident cases of trigeminal neuralgia in all of the seven major markets (the US, Japan, France, Germany, Italy, Spain, and the UK), with the majority of cases seen in the US and Germany.

The forecast for total prevalent cases of the disease suggests the disease represents a bigger burden for the seven major markets than previously thought. Datamonitor epidemiologists forecast there were approximately 822,200 total prevalent cases of trigeminal neuralgia in the seven major markets in 2011.

Trigeminal neuralgia will continue to be diagnosed rarely in all of the major markets, with 33,000 diagnosed incident cases forecasted in the seven major markets in 2021.

Your key questions answered

  • What are the most robust sources for trigeminal neuralgia incidence and prevalence data?
  • How will the patient population change over the next decade in the seven major markets?
  • What are the major risk factors for trigeminal neuralgia that drive the trend in incident and prevalent cases and how are they changing?

Table of Contents

OVERVIEW

  • Catalyst
  • Summary

EXECUTIVE SUMMARY

  • Disease background
  • Forecasted results

DISEASE DEFINITION AND DIAGNOSTIC CRITERIA

  • Disease definition for trigeminal neuralgia
  • Common diagnostic criteria for trigeminal neuralgia

GLOBAL VARIATION AND HISTORICAL TRENDS

  • Limited information is available

DRIVERS OF TRIGEMINAL NEURALGIA EPIDEMIOLOGY

  • Trigeminal neuralgia may be a co-morbidity of multiple sclerosis

EPIDEMIOLOGIC FORECASTING OF TRIGEMINAL NEURALGIA

  • Overview
  • The seven major markets (the US, Japan, France, Germany, Italy, Spain, and the UK)
    • Sources used
    • Methods
    • Sources not used

EPIDEMIOLOGIC RESULTS

  • Diagnosed incident cases of trigeminal neuralgia
  • Average annual growth rate of trigeminal neuralgia diagnosed incidence
  • Age-standardized results for diagnosed incident cases of trigeminal neuralgia
  • Subpopulations for diagnosed incident cases of trigeminal neuralgia
    • Cases will be distributed almost evenly among both genders in each market
    • Adults aged 40 - 59 accounted for 54% of diagnosed incident cases of trigeminal neuralgia in 2011
  • Total prevalent cases of trigeminal neuralgia
  • Average annual growth rate of trigeminal neuralgia total prevalence
  • Age-standardized results for total prevalent cases of trigeminal neuralgia
  • Subpopulations for prevalent cases of trigeminal neuralgia
    • Cases will be distributed almost evenly among both genders in each market
    • Adults aged 50 - 59 accounted for 36.6% of total prevalent cases of trigeminal neuralgia in 2011

DISCUSSION

  • The strength of Datamonitor's epidemiologic projections

BIBLIOGRAPHY

  • Journal articles
  • Websites

APPENDIX

  • Module methodology

TABLES

  • Table: Diagnostic criteria for trigeminal neuralgia
  • Table: Summary of sources used in trigeminal neuralgia analysis
  • Table: Diagnosed incident cases of trigeminal neuralgia in adults over the age of 40 in the seven major markets, 2011 - 21
  • Table: Sex-specific diagnosed incident cases of trigeminal neuralgia in adults over the age of 40 in the seven major markets, 2011
  • Table: Diagnosed incident cases of trigeminal neuralgia in the seven major markets, by age group, 2011
  • Table: Total prevalent cases of trigeminal neuralgia in the seven major markets, 2011 - 21
  • Table: Sex-specific prevalent cases of trigeminal neuralgia in the seven major markets, 2011
  • Table: Total prevalent cases of trigeminal neuralgia the seven major markets in adults aged 50 and over, by age group, 2011

FIGURES

  • Figure: Trends in diagnosed incident cases of trigeminal neuralgia in adults over the age of 40 in the seven major markets, 2011 - 21
  • Figure: AAGR for diagnosed incident cases of trigeminal neuralgia in adults over the age of 40 in the seven major markets, 2011 - 21
  • Figure: Trends in total prevalent cases of trigeminal neuralgia in adults over the age of 50 in the seven major markets, 2011 - 21
  • Figure: AAGR for total prevalent cases of trigeminal neuralgia in adults over the age of 50 in the seven major markets, 2011 - 21
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