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Epidemiology: Asthma - Stable prevalence rates in all age groups will lead to stable case numbers

Abstract

Synopsis

Overview of asthma disease definition and a review of epidemiology literature. This report provides in-depth analysis of patient populations, a 10-year case forecast, and key patient segments across the seven major markets.

Description

INTRODUCTION

Datamonitor estimates that there were 62.9 million diagnosed active asthma cases in the seven major markets in 2011, and these are forecast to rise to 64.8 million total cases by 2021. Stable prevalence rates and modest population increases are responsible for the small change in the number of cases during this period.

FEATURES AND BENEFITS

  • Gain insight into market potential, including robust 10-year epidemiology forecasts of active diagnosed prevalent asthma cases.
  • Gain insight into relevant clinical severity of active diagnosed asthma cases in the seven major markets.
  • Understand the key epidemiologic risk factors associated with asthma.

HIGHLIGHTS

  • Datamonitor expects to see a small increase in the number of diagnosed active prevalent asthma cases from 2011 to 2021 in the seven major markets (the US, Japan, France, Germany, Italy, Spain, and the UK). The number of asthma cases is expected to increase from approximately 62.9 million cases in 2011 to 64.8 million cases in 2021.
  • The largest increase in the number of current asthma cases is expected in the US, where between 2011 and 2021 the number of total prevalent cases of asthma will increase by 0.7% annually. Of the seven major markets, only Japan, Italy, and Germany will experience marginal declines in diagnosed prevalent cases of asthma.

YOUR KEY QUESTIONS ANSWERED

  • What is the number of diagnosed active asthma patients in the seven major markets?
  • How will the patient population change over the next decade in these markets?
  • What is the severity distribution of diagnosed asthma cases?

Table of Contents

OVERVIEW

  • Catalyst
  • Summary

EXECUTIVE SUMMARY

  • Epidemiology of asthma
  • Asthma in the seven major markets
  • Datamonitor's forecast of asthma

DISEASE DEFINITION AND DIAGNOSTIC CRITERIA

  • Asthma background
  • Bronchial challenge test and spirometry can be used for asthma diagnosis
  • Survey is the usual method for collecting data on asthma prevalence

GLOBAL VARIATION AND HISTORICAL TRENDS

  • Asthma is significantly underdiagnosed and undertreated worldwide
  • Asthma prevalence varies widely throughout the world
  • Asthma causes considerable morbidity, diminished quality of life, and mortality worldwide
    • Morbidity
    • Mortality

DRIVERS OF ASTHMA EPIDEMIOLOGY

  • Risk factors
    • Genetic factors are associated with risk of development and severity of asthma
    • Environmental risk factors can lead to a significantly increased risk of asthma symptoms
    • Breastfeeding may provide a protective effect for asthma
    • Socioeconomic status influences physical health, including asthma
    • Occupational exposures are the leading risk factor for asthma development in adulthood
  • Co-morbid conditions
    • Asthma and COPD can be confused in diagnosis
    • Allergic rhinitis and asthma are highly co-morbid
    • Gastroesophageal reflux disease is the second most common co-morbid condition with asthma

EPIDEMIOLOGIC FORECASTING OF ASTHMA

  • Overview
  • Subpopulations
    • Age and gender
    • Severity
  • US
    • Sources used
    • Methods
    • Sources not used
  • Japan
    • Sources used
    • Methods
    • Sources not used
  • France
    • Sources used
    • Methods
    • Sources not used
  • Germany
    • Sources used
    • Methods
    • Sources not used
  • Italy
    • Sources used
    • Methods
    • Sources not used
  • Spain
    • Sources used
    • Methods
    • Sources not used
  • UK
    • Sources used
    • Methods
    • Sources not used

EPIDEMIOLOGIC RESULTS

  • Current prevalent cases of asthma and future trends
    • Severity
    • Age and gender
    • Age-standardized prevalence rates

DISCUSSION

  • Strengths and limits of Datamonitor's epidemiologic projections
  • Conclusions

BIBLIOGRAPHY

  • Journal papers
  • Websites

TABLES

  • Table: ICD-10 codes associated with asthma
  • Table: Data sources used to estimate asthma prevalent cases
  • Table: Global Initiative for Asthma guidelines on severity
  • Table: Total prevalent cases of current asthma in all ages in the seven major markets (000s), 2011-21
  • Table: Total prevalent cases of current asthma in each of the seven major markets, by severity (000s), 2011
  • Table: Age-specific prevalent cases of diagnosed active asthma in the seven major markets, 2011
  • Table: Age-standardized prevalence rates (per 100,000) of active diagnosed asthma in the seven major markets, by gender, 2011

FIGURES

  • Figure: Proportion of age-specific prevalent cases in the seven major markets, 2011
  • Figure: Age-standardized prevalence rates (per 100,000) of active diagnosed asthma in the seven major markets, by gender, 2011
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