Syringes that can be prefilled on standard fill-and-finish lines have had a dramatic effect on the way injectable drugs are developed, prescribed and administered. This impact has been accelerated by the introduction and evolution of autoinjectors - devices that are designed to accept a standard prefilled syringe and form an outer user-friendly device package that simplifies the injection process. While autoinjectors are sometimes designed to work with a particular injectable product as a form of pharmaceutical branding, the typical autoinjector is designed to fit one or more standard sizes of prefilled disposable syringes. Autoinjectors enable a significantly larger segment of the patient population to self-administer injectables. This report analyzes eleven important therapeutic segments and examines the impact of autoinjectors on injectable drug markets.