Bones are biologically active tissues that allow for movement, provide protection for the body's other organs and serve as a production center for red and white blood cells. When bones are diseased or damaged, bone grafts and bone graft substitutes are used for bridging the resulting void or for providing the support that has been lost. The transplanted (or implanted) material provides a scaffold on which the body can generate new bone tissue, thereby repairing the skeletal system. The most common usage of such materials is for dental implants to replace missing teeth. Within the orthopedic field, however, spinal fusion surgeries are the largest driver of bone graft and bone graft substitute usage. Direct competition for bone graft substitutes comes from bone morphogenetic proteins which, although more expensive, are more effective at stimulating bone growth. Another source of competition is the rise of the motion preservation market for spinal surgery.
In this report, bone graft substitute products were segmented into allografts, demineralized bone matrices (DBMs) and synthetics. A common trend seen in the BGS market has been the increase in demand for synthetic materials. Due to the lower ASP and the ease at which these products can be used, demand for synthetics is steadily increasing. In addition to the lower price and easy accessibility, the entire market is being driven by synthetics.
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