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Advanced Drug Delivery Markets (Liposomes, Polymers and Monoclonal Antibodies)

Abstract

Drug delivery is evolving at a rapid rate with new drug product formulations being discovered frequently. Advanced drug delivery deals with developing solutions for new entities in therapeutic pharmacology such as protein and peptides and other novel compounds targeting drugs to specific disease sites including gene therapy. Treatments for chronic conditions and growth in patient-administered drugs are factors leading to greater focus on ease-of-use and convenience. Advanced Drug Delivery Markets (Liposomes, Polymers and Monoclonal Antibodies) details the types of drug delivery systems, technologies and products utilizing advanced drug delivery systems The report describes the industry, its relationship to various healthcare channels, and the trends for the future.

The advanced drug delivery market is two-fold. First of all it identifies drug delivery technology Secondly, it identifies products in the pharmaceutical arena that utilize those drug delivery technologies. Because drug delivery technology is an integral part of sales of pharmaceuticals and drug delivery technology cannot exist without pharmaceuticals, revenues have been reported that include pharmaceutical sales. This report will provide market data that includes the pharmaceutical revenues of those products that utilize advanced drug delivery.

In this report, the advanced drug delivery market is divided into three main segments and market estimates are provided for indications within each category:

  • Liposome Drug Delivery (by Indication - Fungal Infections Cancer, Others)
  • Polymer Drug Delivery (by Indication - Cancer, Neutropenia, Hepatitis, Contraception, Schizophrenia, Acromegaly and Others)
  • Monoclonal Antibodies Drug Delivery (by Indication - Arthritis, Cancer, Multiple Sclerosis, Macular Degeneration, Respiratory Syncytial Virus, Others)

The following types of polymer delivery drugs are segmented within this report.

  • PEGylated Delivery
  • Emulsuion Delivery
  • Injectable Delivery
  • Nanoparticle Delivery
  • Others

A wide range of trends and issues that will impact the advance drug delivery market are discussed in the report including the current state of biotechnolgy expansion, molecular imprinted polymers, hot-melt extrusion, metallofullerenes, nanotechnology advancements and other emerging Drug Delivery technologies not yet on the market.

The following companies are profiled in the report:

  • Alkermes, Inc.
  • ALZA Corporation
  • AP Pharma
  • Centocor Ortho Biotech, Inc.
  • Eisai , Inc
  • Elan Corporation, Plc
  • EnColl Corporation, Inc.
  • Enzon Pharmaceuticals, Inc
  • Gilead Sciences, Inc.
  • Nektar Therapeutics
  • PDL BioPharma
  • pSivida Corp
  • SurModics, Inc
  • Tolmar, Inc

The research conducted by Kalorama Information included comprehensive research of primary and secondary sources such as interviews with company executives, company literature, databases, investment reports, and medical and business journals. New technologies, market developments, and research and development trends and expenditures were identified through patent and data-based searches, as well as via interviews with key personnel. Person-to-person and telephone interviews were the primary method of gathering information. E-mail correspondence was also used in the interview process. Interviews with 24 key industry officials, trade association spokespersons, consultants, healthcare providers, and government personnel were compiled to form the primary basis of information - particularly revenue and market share data- presented in this report.

All market data pertains to the worldwide market at the manufacturers' level and was measured in U.S. dollars. The base year for data was 2010. Historical data are provided for 2006 through 2009, with forecast data provided for 2010 through 2014. Compound annual growth rates (CAGR) are provided for the 2006-2010, 2010-2014 and 2006-2014.

Table of Contents

CHAPTER ONE: EXECUTIVE SUMMARY

  • Overview
  • Market Drivers
  • Market Size and Growth
  • Market Trends

CHAPTER TWO: INTRODUCTION AND OVERVIEW

  • Introduction
  • Scope and Methodology
  • Reasons for Advanced Drug Delivery Systems
  • Phases of Drug Action

CHAPTER THREE: LIPOSOME DRUG DELIVERY

  • Overview
  • Liposome Targeting
  • Passive Targeting
  • Active Targeting
  • New Developments
  • Market Summary
  • Liposome Market by Indication
  • Liposome Market Competitive Analysis

CHAPTER FOUR: POLYMER DRUG DELIVERY

  • Overview
  • Polymeric Implants
  • Biodegradable Polymers
  • Nano- and Microparticulates
  • Polymer Micelles
  • PEGylation Technology
  • Hydrogel Polymers
  • Colloidal systems
  • PLA, PLG, and PLGA
  • Emulsions
  • Proteinaceous microparticles
  • New Developments
  • Market Summary
  • Market for Polymers by Product Type
  • Polymer Market by Indication
  • Polymer Market Competitive Analysis

CHAPTER FIVE: MONOCLONAL ANTIBODY DRUG DELIVERY

  • Overview
  • New Developments
  • Market Summary
  • Monoclonal Antibody Market by Indication
  • Monoclonal Antibody Market Competitive Analysis

CHAPTER SIX: TRENDS AND TECHNOLOGY DEVELOPMENTS

  • Expansion of Biotechnology
  • Incorporation of Technology
  • Molecular Imprinted Polymers
  • Antibiotic Biodegradable Implants
  • Hot-melt Extrusion Technology
  • Sorbent Technology
  • Gene Therapy Drug Delivery
  • Metallofullerenes
  • Antisense Delivery Systems
  • Nanotechnology advancements
  • Camouflaged Nanoparticles
  • Triggerable Drug Delivery
  • Prodrug Drug Delivery
  • Single Chain Antigen-Binding Protein Technology
  • Heat Shock Protein Technology
  • Other Emerging Drug Delivery Technologies

CHAPTER SEVEN: MARKET SIZE AND GROWTH

  • Total Market Summary
  • Geogrpahical Market Growth Summary Competitive Growth Analysis

CHAPTER EIGHT: COMPANY PROFILES

  • Alkermes, Inc.
  • ALZA Corporation
  • AP Pharma
  • Centocor Ortho Biotech, Inc.
  • Eisai , Inc
  • Elan Corporation, Plc
  • EnColl Corporation, Inc.
  • Enzon Pharmaceuticals, Inc
  • Gilead Sciences, Inc.
  • Nektar Therapeutics
  • PDL BioPharma
  • pSivida Corp
  • SurModics, Inc
  • Tolmar, Inc

APPENDIX: COMPANY DIRECTORY

LIST OF EXHIBITS

CHAPTER ONE: EXECUTIVE SUMMARY

  • Table 1-1: The Global Market for Advanced Drug Delivery 2006-2014
  • Figure 1-1: The Global Market for Advanced Drug Delivery 2006-2014

CHAPTER TWO: INTRODUCTION AND OVERVIEW

  • Table 2-1: Sequence of Drug Action

CHAPTER THREE: LIPOSOME DRUG DELIVERY

  • Table 3-1: Marketed Liposome Drugs, as of October 2010
  • Table 3-2: New Developments in Liposome Drugs
  • Table 3-3: The Global Market for Liposomes 2006-2014
  • Figure 3-1: The Global Market for Liposomes 2006-2014
  • Table 3-4: The Global Market for Liposomes by Indication, 2006-2010
  • Figure 3-2: The Global Market for Liposomes by Indication, 2006-2010
  • Figure 3-3: Market for Liposomes by Indication 2006
  • Figure 3-4: Market for Liposomes by Indication 2010
  • Table 3-5: Advanced Drug Delivery: Liposome Market Competitors Revenues and Market Shares 2009
  • Figure 3-5: Advanced Drug Delivery: Liposome Market Competitor Market Shares 2009

CHAPTER FOUR: POLYMER DRUG DELIVERY

  • Table 4-1: Marketed Biodegradable Polymer Drugs, as of October 2010
  • Table 4-2: Marketed Nano- and Micro-particle Drugs, as of October 2010
  • Table 4-3: Marketed PEGylated Drugs, as of October 2010
  • Table 4-4: Marketed Hydrogel Polymer Drugs, as of October 2010
  • Table 4-5: Marketed Emulsions, as of October 2010
  • Table 4-6: New Developments in Polymers
  • Table 4-7: The Global Market for Polymers 2006-2014
  • Figure 4-1: The Global Market for Polymers 2006-2014
  • Table 4-8: Market for Polymers by Product Type 2006-2014
  • Figure 4-2: Market for Polymers by Product Type 2006-2014
  • Figure 4-3: Market for Polymers by Product Type 2010
  • Table 4-9: The Global Market for Polymers by Indication, 2006-2010
  • Figure 4-4: The Global Market for Polymers by Indication, 2006-2010
  • Figure 4-5: Market for Polymers by Indication 2006
  • Figure 4-6: Market for Polymers by Indication 2010
  • Table 4-10: Advanced Drug Delivery: Polymer Market Competitors Revenues and Market Shares 2009
  • Figure 4-7: Advanced Drug Delivery: Polymer Market Competitor Market Shares 2009

CHAPTER FIVE: MONOCLONAL ANTIBODY DRUG DELIVERY

  • Table 5-1: Key Marketed Monoclonal Antibodies, as of October 2010
  • Table 5-2: New Developments in Monoclonal Antibodies
  • Table 5-3: The Global Market for Monoclonal Antibodies 2006-2014
  • Figure 5-1: The Global Market for Monoclonal Antibodies 2006-2014
  • Table 5-4: The Global Market for Monoclonal Antibodies by Indication, 2006-2010
  • Figure 5-2: The Global Market for Monoclonal Antibodies by Indication, 2006-2010
  • Figure 5-3: Market for Monoclonal Antibodies by Indication 2006
  • Figure 5-4: Market for Monoclonal Antibodies by Indication 2010
  • Table 5-5: Advanced Drug Delivery: Monoclonal Antibody Market Competitors Revenues and Market Shares 2009
  • Figure 5-5: 108 Advanced Drug Delivery: Monoclonal Antibody Market Competitor Market Shares 2009

CHAPTER SIX: TRENDS AND TECHNOLOGY DEVELOPMENTS

  • Table 6-1: Nanotechnology Drug Delivery 2010, Companies and Technology

CHAPTER SEVEN: MARKET SIZE AND GROWTH

  • Table 7-1: The Worldwide Market for Advanced Drug Delivery Systems Revenues by Type 2006-2014
  • Figure 7-1: 1 The Worldwide Market for Advanced Drug Delivery Systems Revenues by Type 2006-2014
  • Table 7-2: The Worldwide Market for Advanced Drug Delivery Systems Market Share by Type 2006-2014
  • Figure 7-2: The Worldwide Market for Advanced Drug Delivery Systems Share by Type 2006
  • Figure 7-3: The Worldwide Market for Advanced Drug Delivery Systems Share by Type 2010
  • Figure 7-4: The Worldwide Market for Advanced Drug Delivery Systems Share by Type 2014
  • Table 7-3: Worldwide Advanced Drug Delivery by Geographical Region, 2006-2010
  • Figure 7-5: Worldwide Advanced Drug Delivery by Geographical Region, Sales by Region, 2006-2010
  • Figure 7-6: Worldwide Advanced Drug Delivery by Geographical Region, Percent Sales by Region 2006
  • Figure 7-7: Worldwide Advanced Drug Delivery by Geographical Region, Percent Sales by Region 2010
  • Table 7-4: Worldwide Market for Advanced Drug Delivery System Revenues and Market Share by Supplier 2009
  • Figure 7-8: Worldwide Market for Advanced Drug Delivery Systems Market Share by Leading Supplier 2009
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