• Japanese
  • Korean
  • Chinese
Cover Image

Vaccines 2014: World Market Analysis, Key Players, Trends, Pediatric and Adult Segments (Influenza, Cervical Cancer, Combinations, Hepatitis, Pneumococcal, MMR, Varicella, Poliovirus , HIB, Others)

The global market for human vaccines experienced strong growth through 2013 with the introduction of new vaccines. These new products and other trends are well-covered in Vaccines: The World Market. The Kalorama information report examines the global market for vaccines, covering specifically commercialized vaccines and developmental vaccines for diseases that are already vaccine-preventable.

Vaccination protects not only individuals, but also entire communities from diseases spread by person-to-person transmission. The high growth rates and successful launch of several recent products have kept interest in the global vaccine market high. This report investigates the changes vaccine manufacturers have undergone in the past year, providing world market analysis, identifying the key players, and outlining critical trends in this fast-changing industry.

Included in this report are current market size and forecasts to 2020 for the following vaccines:

Pediatric Vaccines:

  • Pneumococcal
  • Combinations
  • Varicella
  • MMR
  • Poliovirus
  • Hepatitis
  • HIB
  • Other Pediatric

Adult Vaccines:

  • Influenza
  • Cervical Cancer
  • Hepatitis
  • Pneumococcal
  • Travel; DT; Misc.

The global market for vaccines experienced strong growth in many categories through 2013, declines in others, and this is expected to continue through the forecast period. Growth is being fueled by new product introductions and rising usage in all regions.

Kalorama provides a global perspective in this report, including estimates of vaccine sales (pediatric and adult segments) in the following regions:

  • U.S.
  • Rest of North Amer.
  • South America
  • Europe
  • Japan
  • India
  • China
  • Rest of World

Despite ongoing improvements in pediatric vaccination, it is estimated that at least two million children die each year from diseases that could have been prevented by already existing vaccines. This problem is most significant in low income countries, with the health disparity between rich and poor countries resulting in average life spans of about 77 and 52 years, respectively. In addition to this high death toll, millions more suffer disability and illness because they have not been immunized.

Adult immunization is an important, but frequently overlooked, part of patient care. Though vaccination programs typically focus on children, adults in industrialized countries are more likely to die as a result of vaccine-preventable diseases than are children. For example, vaccination can prevent about 50% of deaths from pneumococcal disease and 80% of deaths from influenza-related complications in the elderly. Pharmacoeconomic studies have demonstrated the value of influenza and pneumococcal vaccines; however, immunization rates for these diseases continue to be low in the elderly populations.

Key issues in the global vaccine market today include product safety, refusal to immunize, supply shortages, the use of vaccines to prevent pandemics and address bioterrorism, and innovations in vaccine delivery systems.

The following issues are discussed in this report.

  • Vaccine Safety
  • Refusal to Immunize
  • Obesity
  • Post-Licensure Surveillance
  • The Future of Vaccine Safety
  • Vaccine Shortages
  • Preventing Pandemics
  • Project Bioshield Act
  • National Bio and Agro-Defense Facility
  • DNA Vaccination
  • Mucosal Delivery
  • Intranasal Delivery
  • Vaccine Patches
  • Vaccine Chips and Microneedles
  • Innovations in Vaccine Production
  • Nanoparticle Systems
  • Cloning

This report includes profiles of the key players in vaccines, including:

  • AlphaVax, Inc.
  • Bavarian Nordic A/S
  • Baxter Healthcare
  • Bharat Biotech
  • Crucell /Johnson & Johnson
  • Emergent biosolutions
  • GlaxoSmithKline
  • Medimmune
  • Merck & Co. Inc
  • Novartis
  • Sanofi Pasteur
  • Pfizer

Table of Contents

ONE: EXECUTIVE SUMMARY

  • THE GLOBAL VACCINES INDUSTRY
  • Scope and Methodology
  • Overview
  • Pediatric Preventative Vaccines
  • Adult Preventative Vaccines
  • The Market
  • Issues and Trends

TWO: INTRODUCTION TO VACCINES

  • A Brief History: The Development of Vaccines
  • The Immune Response
  • Mechanism of Action
  • Types of Vaccines
  • Attenuated (Weakened) Live Viruses
  • Killed (Inactivated) Viruses
  • Toxoid Vaccines
  • Genetically Engineered/Modified Vaccines
  • Vaccine Approval Process

THREE: PEDIATRIC PREVENTIVE VACCINES

  • Introduction
  • Childhood Immunization in the United States
  • Childhood Immunization Rates
  • Challenges to the Vaccine Delivery System
  • The Effect of U.S. Healthcare Reform
  • Recommended Childhood Immunization Schedule
  • State Immunization Recommendations
  • United Nations Initiatives
  • Pediatric Vaccine Products
  • BCG
  • Diphtheria, Tetanus, Pertussis, Hepatitis B and Polio
  • Haemophilus Influenzae Type B
  • Hepatitis A
  • Measles, Mumps and Rubella
  • Meningococcal Disease
  • Pneumococcal Conjugate
  • Rotavirus
  • Varicella
  • Pediatric Vaccines in Development
  • Cost of Vaccines in the United States
  • The World Market for Pediatric Preventive Vaccines
  • Total Market Size and Forecast
  • Hepatitis Vaccine Market
  • Haemophilus Influenzae Type B Vaccine Market
  • Measles, Mumps and Rubella Vaccines Market
  • Combination Vaccines Market
  • Pneumococcal Vaccine Market
  • Poliovirus Vaccine Market
  • Varicella Vaccines Market
  • Other Vaccines Market

FOUR: ADULT PREVENTIVE VACCINES

  • Introduction
  • Adult Vaccine-Preventable Diseases: Facts and Figures
  • Global Influenza Surveillance Program
  • U.S. Surveillance
  • Recommendations for Adult Immunizations
  • WHO International Health Regulations
  • Adult Vaccine Products
  • Cervical Cancer
  • Cholera
  • Diphtheria-Tetanus
  • Hepatitis
  • Influenza
  • Japanese Encephalitis
  • Pneumococcal Disease
  • Rabies
  • Shingles
  • Typhoid Fever
  • Yellow Fever
  • Adult Vaccines in Development
  • The World Market for Adult Preventive Vaccines
  • Total Market Size and Forecast
  • Cervical Cancer Market
  • Hepatitis Market
  • Influenza Vaccine Market
  • Travel, DT, and Miscellaneous Vaccine Market

FIVE: VACCINES MARKET SUMMARY

  • Trends Driving the Vaccines Market
  • Market Size and Forecast
  • United States
  • North America
  • South America
  • Europe
  • Japan
  • India
  • China
  • Rest of World
  • Vaccine Market Competitors
  • Pediatric Vaccines
  • Adult Vaccines

SIX: ISSUES AND TRENDS

  • Vaccine Safety
  • Refusal to Immunize
  • Obesity
  • Post-Licensure Surveillance
  • The Vaccine Injury Compensation Program
  • World Health Organization
  • Other Initiatives
  • The Future of Vaccine Safety
  • Vaccine Shortages
  • Preventing Shortages in the Developed Countries
  • Preventing Shortages in Developing Nations
  • Preventing Pandemics
  • U.S. National Vaccine Plan
  • Vaccines and Bioterrorism
  • Overview
  • Project Bioshield Act
  • National Bio and Agro-Defense Facility
  • Vaccine Treatment and Evaluation Units
  • Anthrax
  • Smallpox
  • DNA Vaccination
  • Innovations in Vaccine Delivery Systems
  • Mucosal Delivery
  • Intranasal Delivery
  • Vaccine Patches
  • Vaccine Chips and Microneedles
  • Innovations in Vaccine Production
  • Plants
  • Insects
  • Nanoparticle Systems
  • Cloning

SEVEN: COMPANY PROFILES

  • AlphaVax, Inc.
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
  • Bavarian Nordic A/S
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
  • Baxter Healthcare
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
  • Bharat Biotech
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
  • Crucell /Johnson & Johnson
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
  • Emergent biosolutions
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial
  • GlaxoSmithKline
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
  • Medimmune
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
  • Merck & Co. Inc.
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
  • Novartis
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
  • Pfizer
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information
  • Sanofi Pasteur
  • History and Lines of Business
  • Strategic Alliances
  • Vaccine Products
  • Financial Information

APPENDIX: COMPANY DIRECTORY

LIST OF EXHIBITS

TWO: INTRODUCTION TO VACCINES

  • Table 2-1: Impact of Vaccines in the 20th Century Annual Morbidity in the 20th Century vs 2012
  • Figure 2-1: Attenuated Virus Production
  • Table 2-2: Vaccine-Preventable Diseases, March 2014
  • Table 2-3: VAERS Table of Reportable Events Following Vaccination

THREE: PEDIATRIC PREVENTIVE VACCINES

  • Table 3-1: Total Number of Children Who Died from Diseases Preventable by Vaccines Recommended by the WHO 2012
  • Table 3-2: Immunization Profile of the United States: Population by Age Group, Number of Vaccine-Preventable Diseases Reported by Disease 1990 - 2012
  • Table 3-3: Marketplace Enrollment as a Share of the Eligible Population,December 2013
  • Table 3-4: U.S. Recommended Immunization Schedule for Children Ages 0 Through 18 Years, 2013
  • Table 3-5: Selected Pediatric Vaccines in Development, March 2014
  • Table 3-6: World Market for Pediatric Vaccines by Type (Hep, HiB, MMR,Combinations, Pneumococcal, Polio, Varicella, Others) 2011-2020
  • Figure 3-1: Market Share of Pediatric Vaccines by Type 2013
  • Figure 3-2: Market Share of Pediatric Vaccines, by Type 2020
  • Table 3-7: World Market for Pediatric Vaccines by Region (U.S., North America, South America, EU, Japan, India, China, Rest of World) 2011-2020
  • Table 3-8: World Pediatric Hepatitis Vaccine Market 2011-2020
  • Table 3-9: World Hib Vaccine Market, 2011-2020
  • Table 3-10: World MMR Vaccines Market 2011-2020
  • Table 3-11: World Combination Vaccines Market 2011-2020
  • Table 3-12: World Pediatric Pneumococcal Vaccine Market 2011-2020
  • Table 3-13: World Poliovirus Vaccine Market 2011-2020
  • Table 3-14: World Varicella Vaccine Market 2011-2020
  • Table 3-15: World Pediatric Other Vaccines Market 2011-2020

FOUR: ADULT PREVENTIVE VACCINES

  • Table 4-1: Universal Adult Immunization Schedule 2013
  • Table 4-2: Summary of Recommendations for Adult Immunization
  • Table 4-3: Initiatives to Require HPV Vaccination by U.S. State, 2014
  • Figure 4-1: U.S. Flu Season Severity from 2002 to 2013
  • Table 4-4: WHO Pandemic Classification Schedule
  • Table 4-5: Selected Adult Preventive Vaccines in Development, 2014
  • Table 4-6: World Market for Adult Preventive Vaccines by Type (Hepatitis,Influenza, Pneumococcal, Travel/DT/Misc.), 2011-2020
  • Figure 4-2: Market Share of Adult Vaccines, by Type, 2013
  • Figure 4-3: Market Share of Adult Vaccines, by Type, 2020
  • Table 4-7: World Market for Adult Vaccines by Region (U.S., North America,South America, EU, Japan, India, China, Rest of World) 2011-2020
  • Table 4-8: World Cervical CancerVaccine Market 2011-2020
  • Table 4-9: World Hepatitis Vaccine Market 2011-2020
  • Table 4-10: World Influenza Vaccine Market 2011-2020
  • Table 4-11: 2013 Estimated Population by Region and Selected Age Group
  • Table 4-12: World Pneumococcal Vaccine Market 2011-2020
  • Table 4-13: World Travel; Diphtheria-Tetanus; Miscellaneous Vaccines Market 2011-2020

FIVE: VACCINES MARKET SUMMARY

  • Figure 5-1: Sales Growth of Vaccines vs. Pharmaceuticals 2011-2020
  • Figure 5-2: World Market for Vaccines by Type 2011-2020
  • Table 5-1: The World Vaccines Market by Vaccine Type 2011-2020
  • Figure 5-3: World Market for Vaccines Share by Type, 2011
  • Figure 5-4: World Market for Vaccines Share by Type, 2015 and 2020
  • Table 5-2: The World Vaccines Market by Region 2011-2020
  • Table 5-3: Major Manufacturers' Shares of the World Vaccine Market, 2013
  • Figure 5-5: 2013 World Vaccines Market Share, by Leading Competitors
  • Table 5-4: Major Manufacturer's Shares of the World Pediatric Vaccine Market 2013
  • Figure 5-6: Market Share of Pediatric Vaccines Market, 2013
  • Table 5-5: Major Manufacturer's Shares of the World Adult Vaccine Market 2013
  • Figure 5-7: Market Share of Adult Vaccines Market 2013

SEVEN: COMPANY PROFILES

  • Figure 7-1: AlphaVax Product Pipeline, March 2014
  • Figure 7-2: Bharat Biotech's Product Pipeline, March 2014
  • Figure 7-3: Crucell's Product Pipeline, March 2014
  • Figure 7-4: Emergent Bioslutions' Product Pipeline, March 2014
  • Figure 7-5: Sanofi Pasteur's Product Pipeline, March 2014
Show More
Pricing