Abstract
Descritpion
Pituitary- the master gland of human body is responsible for controlling
crucial hormonal secretion which in turn regulates other key aspects of human
body such as temperature, growth, thyroid functioning, urination and
production of other hormones. It is a pea sized gland situated at the base of
brain and is a major component of human body as it expedites the response
towards the surrounding environment and settings.
Any deformity or damage to the pituitary gland can adversely impact the
production and activity level of the above mentioned hormones thereby
affecting the body work process and stunting the outcomes especially in the
case of growth hormone. Marred pituitary function leads to either over or
under secretion of the somatrpopin that is the growth hormone. Its over
secretion causes disfiguration in the body parts like hands, face, feet etc.
whereas its deficiency impedes the growth of body parts/whole body thus
leading to disease states like dwarfism or gigantism.
It is observed that the growth hormone related problems usually affect
children and teenagers, but it is seen to grip adults as well but to a lesser
extent. The major factors which vitiate the pituitary operations thus
impairing the GH role include kidney malfunction, tumors/cancer especially
associated with brain. There are some other unknown causes as well which are
termed as idiopathic. Earlier, to deal with these predicaments, growth hormone
(GH) used to be extracted from the human cadavers but, as time passed and
evolution of technology/tools/techniques/R&D took place, the extraction of GH
also got altered and many novel innovations and discoveries were made in the
respective field.
Now a days, many leading companies are heavily involved in the R&D process for
devising longer acting and sustained release versions of the somatropin which
are produced using the recombinant technology. The competition prevalent in
the respective industry is heating up day by day. The human growth hormone
market (HGH) is monopolized by a few players viz. Pfizer, NovoNordisk, Eli
Lilly and Roche.
The global HGH report discusses the key ongoing trends like licensing
agreement, development of needle free injectors and comparison between generic
and biosimilar drug versions. On the industry development front, the current
inclination is towards creating innovative therapeutic products with novel
properties. Furthermore, the major factors driving the HGH market include
rising cancer and CKD/ESRD cases and increasing GNI and healthcare expenditure
on worldwide basis. In addition, a few factors posing challenges in front of
the HGH industry are the off-label HGH use, associated risks and side effects
and the escalating price pressure which, to an extent, are hindering the
growth and development of the same.
By combining SPSS Inc.' s data integration and analysis capabilities with our
relevant findings, we have predicted the future growth of the industry. We
employed various significant variables that have an impact on this industry
and created regression models with SPSS Base to determine the future direction
of the industry. Before deploying the regression model, the relationship
between several independent or predictor variables and the dependent variable
was analyzed using standard SPSS output, including charts, tables and tests.
Table of Contents
1. Human Growth Hormone
- 1.1 Physiological Effects of Growth Hormone
- 1.2 GH Secretion Control
- 1.3 GH Deficiency (GHD)
- 1.4 Therapeutic and Other Uses of GH/HGH
- 1.5 Recombinant Human Growth Hormone (rHGH)
2. Global HGH Market Size
- Market Value
- Market Share
- 2.1 HGH-CTP Market Opportunity Model
- 2.2 SRhGH Market Opportunity Model
3. Market Dynamics
- 3.1 Key Trends
- 3.1.1 Strategic Agreements
- 3.1.2 Inclination towards Needle-Free Injectors
- 3.1.3 Generic Vs Biosimilar Version of the drugs
- 3.2 Industry Developments
- 3.2.1 New Products under Development
- 3.3 Growth Drivers
- 3.3.1 Increasing Prevalence of Cancer
- 3.3.2 Increasing Cases Chronic Kidney Disease (CKD)
- 3.3.3 Rising Healthcare Expenditure
- 3.3.4 Increasing Global GNI (Gross National Income)
- 3.4 Challenges
- 3.4.1 Unapproved/off-label Uses of HGH
- 3.4.2 Possible Side Effects and other Associated Risks
- 3.4.3 Escalating Price Pressure
4. Competitive Landscape
- Competitive Overview
- Market Share
5. Company Profiles
- 5.1 Roche Holdings AG
- Business Overview
- Financial Overview
- Business Strategies
- Focus On Innovative Pharmaceuticals
- Leverage Expertise in Molecular Biology
- 5.2 Novo Nordisk
- Business Overview
- Financial Overview
- Business Strategies
- Focus on Hormone Therapy
- Leadership in Hemophilia Treatment
- 5.3 Pfizer, Inc.
- Business Overview
- Financial Overview
- Business Strategies
- Focus on Growth
- Strategic Acquisitions
- 5.4 Eli Lilly and Company
- Business Overview
- Financial Overview
- Business Strategies
- Focus on Novel Therapeutic Molecules
- Capacity Expansion
6. Market Outlook
- 6.1 Market Forecast
- 6.2 Forecast Methodology
- 6.2.1 Dependent and Independent Variables
- 6.2.2 Correlation Analysis
- 6.2.3 Regression Analysis
List of Charts
- GH's Physiological Effect
- GH Secretion Control
- Global HGH Market Share (2010)
- Global Human Growth Hormone Market (2004-2010)
- Global hGH-CTP Market Opportunity (2014E-2020E)
- Market Share of Chemical Drugs and Biologics as per Drug Versions
- Number of Cancer Cases Worldwide (2007-2011)
- Worldwide Patients with End Stage Renal Disease (2005-2011)
- Global Healthcare Spending (2005-2015E)
- World Gross National Income (2005-2010)
- Growth Hormone Volume Market share (February 2007-February 2012)
- Roche's Revenues by Business Segments (2011)
- Roche's Revenues and Net Income, 2007-2011
- Novo Nordisk Revenue Share by Business Segments (2011)
- Novo Nordisk Revenues & Net Income (2008-2011)
- Pfizer's Revenue Share by Business Segments (2011)
- Pfizer's Revenues & Net Income (2008-2011)
- Eli Lilly's Revenues by Segment (2011)
- Eli Lilly's Revenue and Net Income (2008-2011)
- Global HGH Market Forecast (2009-2014E)
List of Tables
- Worldwide Revenues of Marketed hGH Products (2011)
- hGH-CTP US Market Opportunity Model (2014E-2020E)
- hGH-CTP European Market Opportunity Model (2014E-2020E)
- SRhGH Market Opportunity Model (2013E-2020E)
- Annual US Sales of rHGH and Injectors
- LG Life Sciences Product under Development
- Sustained-release HGH under Development Worldwide
- Prolor's Product under Development
- GH Products Devised by NovoNordisk
- Growth Hormone Volume Market share (February 2007-February 2012)
- Dependent & Independent Variables (2006-2011)
- Correlation Matrix
- Model Summary - Coefficient of Determination
- Regression Coefficients Output
Global Human Growth Hormone Market Report: 2012 Edition published by Koncept Analytics in October 5, 2012. This report consists of 42 Pages and the price starts from US $ 800.