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Competitor Analysis: Cancer Antibodies in Early Clinical Development

The present Competitive Intelligence Report about Cancer Antibodies in Early Clinical Development provides a competitor evaluation in the field of antibody therapeutics being developed for treatment of solid and hematologic malignancies as of February 2011. Purchase of the downloadable pdf report includes a 6-month online access to the data of the report and any updates since the publication date. Credentials to access the database will be sent by e-mail and allow online work with the project data to print or export an individual report.

Marketed therapeutic antibodies for treatment of cancer achieved combined sales of over US$ 18 bln in the year 2009. Among them are the blockbuster antibodies Avastin, Rituxan/MabThera and Herceptin. The development pipeline of novel cancer antibodies in early clinical phases is full, not only of antibodies against the validated targets CD20, VEGF and Her2, but also of many new and unique antibodies directed against novel targets which will have to show its clinical validity. The technology of antibody-drug conjugates is gaining popularity as evidenced by an ever growing pipeline.

The report includes a compilation of currently active projects in early clinical research and development of antibody therapeutic for treatment of cancer. In addition, the report lists company-specific R&D pipelines of anti-cancer antibodies. Competitor projects are listed in a tabular format providing information on:

  • Drug Codes,
  • Target / Mechanism of Action,
  • Class of Compound,
  • Company,
  • Product Category,
  • Indication,
  • R&D Stage and
  • additional comments with a hyperlink leading to the source of information.

Index

  • Antibody Drug Conjugates (ADC)
  • Immunotoxins
  • Immunocytokines
  • CD19
  • CD20
  • CD22
  • CD30
  • CD40
  • IGF-1/R
  • PDGF-R
  • EGF-R
  • Her2
  • VEGF-R
  • FGF-(R)
  • TGF-(R)
  • CEA
  • EpCAM
  • PSA & PSMA
  • c-Met/HGF
  • TRAIL-R1/2
  • B7 - CD28/CLTA4 Pathway
  • Delta-like ligand 4 (DLL4) inhibitor (DLL4 = vascular-specific notch ligand)
  • IL-6
  • Angiopoietin
  • CCR2 chemokine receptor
  • ErbB3 / Her3
  • CD38
  • Unique Antibodies

Corporate Early Clinical Stage Cancer Antibody R&D Pipelines

  • Abbott
  • Active Biotech
  • Affimed Therapeutics
  • Albert Einstein College of Medicine
  • Alder Biopharmaceuticals
  • Alexion Pharmaceuticals
  • Altor Biosciences
  • Amgen
  • Angimmune
  • Apeiron Biologics
  • Apogenix
  • Astellas Pharma
  • AstraZeneca
  • AVEO Pharmaceutical
  • Bayer Schering Pharma
  • Biocon
  • Biogen Idec
  • BioInvent
  • Biotest
  • BioWa
  • Boehringer Ingelheim Pharmaceuticals
  • Bristol-Myers Squibb (BMS)
  • BZL Biologics
  • Celldex Therapeutics
  • Celltrion
  • Centocor (J&J)
  • CureTech
  • Daiichi-Sankyo
  • Debiopharm
  • Dong-A Pharmaceutical
  • Eisai
  • Eli Lilly
  • Emergent Biosolutions
  • Fibrogen
  • Five Prime Therapeutics
  • Fresenius Biotech
  • Ganymed Pharmaceuticals
  • Genmab
  • Genzyme
  • GlaxoSmithKline
  • Glycotope
  • Helix BioPharma
  • Hokkaido UniversityHospira
  • Human Genome Sciences
  • ImaginAb
  • ImmunogenImmunomedics
  • Innate Pharma
  • Kissei Pharmaceutical
  • Kyowa Hakko Kirin Pharma
  • LFB Biotechnologies
  • Life Science Pharmaceuticals
  • Lpath
  • Ludwig Institute for Cancer Research (LICR)
  • MAbgen
  • MacroGenics
  • MAT Biopharma
  • MD Anderson Cancer Center
  • Memorial Sloan Kettering
  • Mentrik Biotech
  • Merck & Co
  • Merck Serono
  • Merrimack Pharmaceuticals
  • Micromet
  • MorphoSys
  • National Cancer Institute (NCI)
  • Neogenix Oncology
  • Novartis
  • Ono
  • OncoMed Pharmaceuticals
  • Oncoscience
  • Pain Therapeutics
  • PanGenetics
  • Patrys
  • Peregrine Pharmaceutical
  • Pfizer
  • Philogen
  • Progenics
  • Provenance Biopharmaceuticals
  • Quest PharmaTech
  • Radboud University
  • Recepta Biopharma
  • Regeneron Pharmaceuticals
  • Roche (Genentech)
  • Sanofi-Aventis
  • Seattle Genetics
  • Scott & White Hospital and Clinic
  • Simmons Cancer Center
  • Spectrum Pharmaceuticals
  • Symphogen
  • Takeda
  • Targa Therapeutics
  • TenX Biopharma
  • Teva Pharmaceutical Industries
  • ThromboGenics
  • TopoTarget
  • TRACON Pharmaceutical
  • TRION Pharma
  • United Therapeutics
  • UCB
  • Vaccinex
  • Viventia Biotech
  • Weill Medical College
  • Wilex
  • XBiotech
  • Xencor
  • XOMA
  • YM Biosciences
  • Zenotech

About Competitor Analysis Series:

The Competitor Analysis Series delivers NO-FRILLS, but concise information about the pipeline of R&D projects for targets, diseases, technologies and companies at low prices. The information is provided in a tabular format and fully referenced.

Table of Contents

1. Cancer Antibodies in Early Clinical Development

  • Antibody Drug Conjugates (ADC)
  • Immunotoxins
  • Immunocytokines
  • CD19
  • CD20
  • CD22
  • CD30
  • CD40
  • IGF-1/R Antagonists
  • PDGF-R Antagonists
  • EGF-R Antagonists
  • Her2 Receptor Antagonists
  • VEGF-R Antagonists
  • FGF-(R) Antagonists
  • TGF-(R) Antagonists
  • CEA
  • EpCAM
  • PSA & PSMA
  • c-Met/HGF
  • TRAIL-R1/2
  • B7 - CD28/CLTA4 Pathway
  • Delta-like ligand 4 (DLL4) inhibitor (DLL4 = vascular-specific
  • notch ligand)
  • IL-6
  • Angiopoietin
  • CCR2 chemokine receptor
  • ErbB3 / Her3 Antagonists
  • CD38
  • Unique Antibodies

2. Corporate Cancer Antibodies in Early Clinical

  • Development R&D Pipelines
  • Abbott
  • Active Biotech
  • Affimed Therapeutics
  • Albert Einstein College of Medicine
  • Alder Biopharmaceuticals
  • Alexion Pharmaceuticals
  • Altor Biosciences
  • Amgen
  • Angimmune
  • Apeiron Biologics
  • Apogenix
  • Astellas Pharma
  • AstraZeneca
  • AVEO Pharmaceutical
  • Bayer Schering Pharma
  • Biocon
  • Biogen Idec
  • BioInvent
  • Biotest
  • BioWa
  • Boehringer Ingelheim Pharmaceuticals
  • Bristol-Myers Squibb (BMS)
  • BZL Biologics
  • Celldex Therapeutics
  • Celltrion
  • Centocor (J&J)
  • CureTech
  • Daiichi-Sankyo
  • Debiopharm
  • Dong-A Pharmaceutical
  • Eisai
  • Eli Lilly
  • Emergent Biosolutions
  • Fibrogen
  • Five Prime Therapeutics
  • Fresenius Biotech
  • Ganymed Pharmaceuticals
  • Genmab
  • Genzyme
  • GlaxoSmithKline
  • Glycotope
  • Helix BioPharma
  • Hokkaido University
  • Hospira
  • Human Genome Sciences
  • ImaginAb
  • Immunogen
  • Immunomedics
  • Innate Pharma
  • Kissei Pharmaceutical
  • Kyowa Hakko Kirin Pharma
  • LFB Biotechnologies
  • Life Science Pharmaceuticals
  • Lpath
  • Ludwig Institute for Cancer Research (LICR)
  • MAbgen
  • MacroGenics
  • MAT Biopharma
  • MD Anderson Cancer Center
  • Memorial Sloan Kettering
  • Mentrik Biotech
  • Merck & Co
  • Merck Serono
  • Merrimack Pharmaceuticals
  • Micromet
  • MorphoSys
  • National Cancer Institute (NCI)
  • Neogenix Oncology
  • Novartis
  • Ono
  • OncoMed Pharmaceuticals
  • Oncoscience
  • Pain Therapeutics
  • PanGenetics
  • Patrys
  • Peregrine Pharmaceutical
  • Pfizer
  • Philogen
  • Progenics
  • Provenance Biopharmaceuticals
  • Quest PharmaTech
  • Radboud University
  • Recepta Biopharma
  • Regeneron Pharmaceuticals
  • Roche (Genentech)
  • Sanofi-Aventis
  • Seattle Genetics
  • Scott & White Hospital and Clinic
  • Simmons Cancer Center
  • Spectrum Pharmaceuticals
  • Symphogen
  • Takeda
  • Targa Therapeutics
  • TenX Biopharma
  • Teva Pharmaceutical Industries
  • ThromboGenics
  • TopoTarget
  • TRACON Pharmaceutical
  • TRION Pharma
  • United Therapeutics
  • UCB
  • Vaccinex
  • Viventia Biotech
  • Weill Medical College
  • Wilex
  • XBiotech
  • Xencor
  • XOMA
  • YM Biosciences
  • Zenotech
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