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Q1 2011 Emerging Medical Technologies Spotlight: A Report of Investment and Partnering Opportunities

Notice
This publication has been discontinued on July 14, 2012.

Abstract

This report includes details on 140 emerging medical technology companies that: have presented at a Q1 2011 Elsevier/Medtech Insight In3 investor/partnering conference; have presented at a Q1 2011 LSI Emerging Medical Technologies Spotlight meeting; or have been identified by LSI' s in-house research team in Q1 2011. Two- to three-page executive summaries are provided on most of the companies.

Executive summaries typically include:

  • Company Contact Information
  • Company Overview (structure, size, year founded, etc.)
  • Competitive Landscape
  • Technological Advantage
  • Stage of Development
  • Target Markets
  • Financial Summary and Sales Forecasts
  • Financing & Partnering Needs
  • IP Position & Status
  • Management Team
  • Exit Strategy
  • More

All companies include technology, market(s), key executive, and contact information.

Coverage includes innovations in a broad spectrum of medical technology areas including:

  • 5 Aesthetics/Dermatology Companies
  • 33 Biomaterials Companies
  • 6 Biotechnology/Cell Therapy Companies
  • 24 Cardiovascular Companies
  • 6 Dental Companies
  • 23 Diagnostics Companies
  • 19 Drug Delivery Companies
  • 11 Endocrine Companies
  • 8 Gastroenterology Companies
  • 8 Gynecology/Women' s Health Companies
  • 10 Imaging Companies
  • 9 Neurology Companies
  • 16 Oncology Companies
  • 12 Ophthalmology Companies
  • 14 Orthopedics Companies
  • 5 Pain Management Companies
  • 17 Patient Monitoring/Management Companies
  • 8 Respiratory Companies
  • 13 Spine Companies
  • 9 Surgery Companies
  • 13 Urology Companies
  • 17 Vascular Companies
  • 7 Wound Management Companies

**Some of the content in this report is generated from LSI' s exclusive license agreement with Elsevier/Medtech Insight to reproduce content from their In3 conferences. ***Coverage of companies from Q1 2011 is included in this report.

Table of Contents

BRIEF TECHNOLOGY DESCRIPTIONS FOR COMPANIES COVERED

  • 1-Trans-nasal catheter for real-time imaging of atrial fibrillation (AF) ablation procedures; 2-Intra-cardiac catheter for real-time image guidance of percutaneous valve and other structural heart repair procedures; 3-High-definition intravascular ultrasound (IVUS) system, with near-OCT image resolution; and 4-Image-guided, endoventricular injection catheter for stem cell and/or biological agent therapy for congestive heart failure (CHF)
  • 1-A long-term cardiac rhythm monitor and 2-A disposable electrocardiography (ECG) monitor for use for up to 30 days
  • 1-Adult stem cell collection and storage, 2-VSEL(TM) (very small embryonic-like) stem cells for tissue regeneration, 3-Contract cell manufacturing for clients around the world, Progenitor Cell Therapy, 4-Therapeutics such as a T-cell regulatory technology to treat disorders of the immune system, 5-A wound healing technology that uses autologous bone marrow-derived stem cells, 6-An autologous bone marrow-derived cell line selected to treat damaged heart muscle following AMI
  • 1-Biochemical sensing technologies for continuous glucose monitoring and 2-Drug-delivery devices for osteoporosis management
  • 1-Biopsy needles with enhanced ultrasound visualization, 2-Microencapsulated tissue markers, 3-Devices for the local, accurately positioned, chemoablative treatment of soft tissue cancers
  • 1-Deep brain stimulator (DBS) to treat movement disorders, 2-A hybrid auditory implant (HAI) to treat severe hearing loss
  • 1-Effective cryosurgical tool that is simple and safe to use without cryogenic gasses or liquids for all medical office skin lesion removal needs, 2-Cervical freeze attachment for gynecology use, 3-Third-generation technology to accommodate cryosurgical treatments for prostate, liver & renal cancers and cardiac aberrant foci ablation
  • 1-Non-invasive in vitro diagnostic (IVD) blood test for the detection and/or monitoring of 14 different types of cancer, 2-Combination Immunogene Therapy (CIT) technology that could lead to a vaccine or possibly treat those already diagnosed with cancer
  • 3-D full-breast ultrasound imaging device for the detection of benign or malignant masses
  • 510(k) cleared device using acoustic reflectometry to continuously monitor breathing tubes for placement, movement, and obstruction, enabling adverse event prevention
  • A business and technology research & development platform, dedicated to delivering innovative solutions for the musculoskeletal disorders industry
  • A handheld breath analyzer for the measurement of fat metabolism
  • A handheld device for the as-needed treatment of allergic rhinitis
  • A low-cost, clip-on eye-piece for mobile phones that mimics and replaces the expensive laser-based Shack-Hartmann wavefront aberrometers to diagnose the most common refractive eye disorders: myopia (nearsightedness), hypermetropia (farsightedness), astigmatism, and presbyopia (age-related visual impairment)
  • A medical implant surface technology company focused on the design and manufacturing of proprietary and cellular-friendly interbody fusion devices for the spine
  • A minimally invasive, green, laser-based technology for the treatment of benign prostatic hyperplasia (BPH), as an alternative to traditional TURP surgery
  • A non-invasive, automatic analyzer that uses measurements of sweat gland activity to determine whether a patient is at risk for diabetes
  • A non-invasive, portable device that treats glioblastomas with electrical fields
  • A percutaneous implant for mitral valve repair
  • A Peripheral Nerve Stimulation (PNS) system for patients suffering from severe, intractable pain
  • A point-of-care diagnostic system for rapid, sensitive, quantitative biomarker panels that delivers laboratory-quality results in a clinic or doctor' s office, within minutes
  • A removable surgical implant to improve vision loss resulting from presbyopia
  • A revolutionary device that will facilitate broad implementation of extracorporeal CO2 removal and oxygen supplementation resulting in the avoidance of airway intubation, sedation, and invasive mechanical ventilation
  • A safe, simple, and cost-effective solution that will revolutionize the vascular anastomosis procedure
  • A self-contained, leadless electrode and an independent miniature pacemaker for the left side of the heart, based on a novel micro-generator that harvests energy from the movement of the heart
  • A small, injectable ophthalmic implant containing multiple, laser-activated reservoirs designed for the on-demand, physician-controlled release of ocular drug therapies to the back of the eye
  • A thrombectomy catheter for peripheral artery disease (PAD) that features a rotating, extending tip
  • A unique Sharklet-patterned urinary catheter that will reduce catheter-associated urinary tract infections (CAUTIs)
  • A unique, non-invasive tool for the analysis of muscle function to assist in the evaluation and treatment of neck and back injuries and illnesses
  • A vertebral restoration system that uses spine-specific osteogenic biomaterials to restore vertebral stability
  • A wearable product that uses Touch Activated Phlebotomy (TAP) technology to reduce the inconvenience of blood sampling and facilitate simpler diagnoses
  • A wireless, remote-controlled unit targeting tissue expansion for breast reconstruction
  • A wireless, touch-screen insulin pump featuring a blood glucose meter, food library, and an activity monitor
  • Advanced long-term hemodialysis and peritoneal dialysis catheters
  • Advanced surgical devices for ear, nose, and throat (ENT) surgery
  • An artificial silicone microchip, which stimulates retinal cones and rods to restore retinal function
  • An automated, continuous glucose monitor for bedside use in intensive and critical care
  • An elegant, user-friendly alternative to traditional eye dropper bottles that will allow multi-dose of preservative-free ophthalmic formulations
  • An expandable, funnel-shaped cannula for the removal of intravascular material during extracorporeal circulation
  • An implantable, bionic retina for patients with degenerative retinal diseases
  • Anatomically appropriate orthopedic implants, unique instrumentation, and biologics for pediatric and small stature patients
  • Anti-infective compounds designed to mimic host defense proteins, but with completely synthetic/non-peptide backbones, for serious, life-threatening, acute disorders
  • Atherosclerotic plaque dissolution through chemical means for treating occlusive and non-occlusive atherosclerotic disease that may reduce the need for permanent implants like drug-eluting stents (DES), while also potentially addressing plaque instability
  • Best-in-class platform to optimize genes and proteins in human therapeutics
  • Biocellulose technology that eliminates the risks/complications/limitations inherent in animal, human, and synthetic biomaterials
  • Biocompatible and biodegradable synthetic scaffold to aid soft tissue regeneration of the anterior cruciate ligament (ACL) of the knee
  • Blood tests for the early detection of breast cancer, ovarian cancer, lung cancer, Alzheimer' s, and other serious diseases where significant unmet clinical needs exist
  • Capsule-based hydrogels to reduce food intake in obese patients
  • Cloud/web-based medical imaging data management software and infrastructure as services - to replace picture archiving communication system (PACS) at a significantly reduced cost
  • Compact, home-based device for male fertility assessment
  • Continuous glucose monitoring system using an intravascular, optical fluorescence-based sensor to support clinical implementation of tight glycemic control (TGC) in the intensive care unit (ICU)
  • Device for dry powder pulmonary delivery to treat patients with Parkinson¥' s disease
  • Device for the early detection, assessment, and monitoring of mild perceptual impairment (MPI), an early indicator of mild cognitive impairment
  • Device providing sustained intravesical drug delivery for the treatment of Overactive Bladder (OAB), Interstitial Cystitis (IC), and other bladder conditions
  • Device that delivers iron transdermally for patients with iron-deficiency anemia
  • Device that prepares 10 million micro-droplets per hour for use in drug discovery, genomics, molecular epidemiology, and proteomics
  • Device-based technology with an anti-inflammatory therapeutic platform to appreciably widen the present window of treatment for ischemic stroke to 12-18 hours
  • Devices for arthroscopy, hip, knee, and spine surgery, in addition to radiofrequency identification (RFID) tracking technology
  • Dynamic and intelligent optics for use in spectacle lenses for the correction of presbyopia
  • Effective and convenient phototherapy system available for in-home treatment of scalp/small-area psoriasis and other photo-responsive skin diseases
  • Effective antimicrobial coatings and compounds that are broad-spectrum and fast-acting against clinically relevant pathogens, including multi-drug resistant strains such as MRSA
  • Electro-grafting coating technology for implantable biomedical applications; used for the fast healing post drug-eluting-stent (DES) implantation (avoiding late stage thrombosis)
  • Ellanse, the first dermal filler family offering a complete customized solution in medical aesthetics
  • Endovascular device targeting the treatment of abdominal aortic aneurysms (AAAs)
  • Fish-skin-derived tissue regeneration technology for chronic wounds and hernia repair that improves upon current human and porcine technologies through improved economics & clinical performance, reduced disease transfer risk, and absence of cultural constraints on usage
  • Fluorescent markers/optical sensors that provide an accurate and rapid determination of kidney function
  • Full Sense(TM) Bariatric Device which is implanted and extracted via endoscopy and causes satiety leading to weight loss
  • Functional optical imaging technology for the early diagnosis and guided treatment of blinding retinal diseases and diseases of other organs of the body; it is the only optical imaging approach that allows visualization of the capillaries, non-invasively (without any contrast agent)
  • Grafts for small diameter (less than 5mm) artificial blood vessels in both peripheral and coronary applications
  • Handheld device for monitoring chronic disease home-care patients using a single drop of blood
  • Hand-held ultrasound tool that displays a see-through image in the medical practitioner' s line of sight, at the patient' s skin surface
  • High-durability tissue heart valves for transcatheter and surgical implantation with percutaneously-exchangeable leaflets for lifetime service without anti-coagulation therapy
  • HistoScanning(TM) is an innovative imaging-based modality available in the Tissue Characterization market; the only one offering accurate 3D detection and localization of cancer lesions
  • Image-guided interventional endoscopy products
  • Imaging systems enabling the examination of epithelial tissues in the bladder, cervix, colon, esophagus, lung, oral cavity, and stomach
  • Imaging systems for the non-invasive, in vivo detection of cancerous and pre-cancerous lesions
  • Implantable device to treat epilepsy by anticipating seizures and delivering intracranial drugs
  • Implantable hearing device that provides extraordinary acoustic performance in a completely invisible device
  • Implantable neurostimulation system for the treatment of obstructive sleep apnea (OSA)
  • Implantable pacing and defibrillation device that detects the early onset of atrial fibrillation and chronic heart failure and delivers targeted medications
  • Incubator with 12 fully owned portfolio companies and 20+ fully owned pipeline technologies, driven by unmet market need
  • Incubator with over 100 highly novel medical technology inventions spanning most medical markets
  • Injectable, synthetic bone subsitutes
  • Innovative hydrogel technology for tissue repair including cartilage, bone, and dermal of the knee, wrist, elbow, shoulder, and ankle
  • Innovative, compact, non-invasive systems for the early detection of skin, lung, colon, and cervical cancers
  • Less invasive technologies and a more effective option for Primary Open Angle Glaucoma patients
  • Medical image viewing solution that enables physicians to access/view critical patient images/information from anywhere, without compromising the security/privacy of the data
  • Microwave-based soft tissue ablation
  • Minimally invasive catheter-based system that safely, rapidly, and effectively removes thrombus and restores blood flow in the peripheral vasculature utilizing ultrasound energy to destroy clots, without harming adjacent healthy tissue or generating dangerous emboli
  • Minimally invasive interstitial laser therapy (ILT) as an alternative to lumpectomy
  • Minimally invasive orthopedic device for the treatment of hip pain
  • Minimially invasive percutaneous implantable cardioverter defibrillator (PICD) for the treatment of cardiac arrhythmias
  • Modular, powered, proprietary articulating technology for endoscopes and laparoscopes, enabling surgical safety, flexibility, and procedural innovations
  • Next-generation extracellular matrix (ECM) products for advanced wound healing and tissue regeneration, with improved handling, strength, resorbability, and infection control over existing products
  • Next-generation medical devices with anti-fouling surface modifications that reduce the risk of complications over long durations
  • Next-generation, cost-effective ophthalmic implants made from STAR(R) biomaterial that will help patients suffering from glaucoma and corneal blindness
  • Non-invasive device using muscular counter pulsation (MCP) technology for the treatment of acute and chronic heart failure (CHF) in a clinical, ambulatory, or at-home setting
  • Non-invasive devices for continuous real-time evaluation of hemodynamic changes
  • Non-invasive method for detecting the presence of a right-to-left cardiac shunt (i.e., PFO) to enable medical treatment and/or closure before the occurrence of a debilitating or life-threatening stroke or heart attack
  • Non-invasive ultrasound device for the treatment of glaucoma
  • Non-invasive, controlled, and sustained release back-of-the-eye therapeutics for sight-threatening diseases such as: severe uveitis, diabetic macular edema, and age-related macular degeneration (AMD)
  • Non-invasive, rapid assessment of dP/dt in Cardiac Resynchronization Therapy (CRT) for lead placement, lead optimization, and monitoring
  • Novel bioresorbable regenerative scaffolds that provide 3D architecture for enhanced tissue repair
  • Novel implantable ultrasound flow-measuring devices with flow data wirelessly transmitted from within the body
  • Novel, implantable cardiovascular device
  • Off-the-shelf implantable allograft tissue to support peripheral nerve repair and regeneration
  • Percutaneous vertebral augmentation (PVA) system for controlling bone cement delivery and leakage during spinal surgery
  • Percutaneously-inserted interspinous process fusion cages that provide for stabilization of the spine
  • Permanent, catheter-based implant that reduces mitral regurgitaiton by reshaping the mitral valve
  • Physical and chemical resurfacing of orthopedic implants and stents which allows for drug elution without the use of a binding polymer
  • Portable and advanced point-of-care diagnostics equipment
  • Portable pediatric vision-screening device for early diagnosis of serious vision abnormalities
  • Portable, disposable, non-powered suction device for negative pressure wound therapy (NPWT)
  • Pressure-controlled Intermittent Coronary Sinus Occlusion (PICSO) device for acute coronary syndrome (ACS) and heart failure patients
  • Proprietary medical devices and patient interfaces for the enhancement of patient safety through capnography monitoring
  • Radiofrequency (RF)-based detection systems to reduce the risk of retained surgical sponges
  • Radiofrequency (RF)-based device for the treatment of congestive heart failure (CHF)
  • Remote (wireless) continuous EEG (cEEG) brain monitoring of critical care patients that significantly reduces mortality rates, improves patient outcomes, and saves millions of dollars in patient care expense
  • Remotely controlled percutaneous catheter system for use in a wide range of interventional applications
  • Repair and regeneration technology platforms designed to mend and regrow hard tissue (such as bone) and soft tissue (such as cartilage)
  • Revolutionary portable device to provide easy and efficient screening methods for early detection of age-related macular degeneration, diabetic maculopathy, and other types of retinal disease in the human eye
  • Spine implant system that stabilizes and restores the spinal anatomy of persons that have suffered a vertebral compression facture (VCF)
  • StimBrace addresses osteoarthritic knee pain by intelligently strengthening leg muscles to stabilize and brace the knee during real-world use
  • Sutureless, anastomotic connectors to provide a controlled method of joining vessels
  • Synthetic cartilage technology for joint repair
  • Technology for nurses/pharmacy technicians/emergency responders to more safely and effectively vaccinate the public in the event of a biological or viral pandemic
  • Technology that combines diagnostic imaging and therapeutic laser into one device enabling image-guided navigation when performing retina laser procedures, with the potential to reduce: treatment time, retreatment rates, and risk of complications
  • Technology to embed Nitric Oxide (NO), part of the innate immune system, into polymer medical devices to make them antimicrobial without the issues of antibiotic resistance
  • Teraherz-based, real-time, video-rate imaging system
  • The first robotic system capable of offering full force-reflection to laparoscopic surgeons in any surgical practice
  • The NuLens(TM) Dynacurve IOL is an implantable, flexible lens that changes it curvature in response with the movements of the eyes accommodative muscle system
  • The only device enabling simultaneous, non-invasive, and continuous measurement of blood flow and oxygen saturation
  • The only minimally invasive cure for spinal stenosis that maintains the natural dynamics of the spine
  • Thrombectomy catheters for patients with peripheral artery disease (PAD)
  • Two clinically proven lumbar, motion-preservation spinal implants that offer surgeons: 1-a lumbar joint replacement that has provided superior treatment over fusion and disc replacement, for patients with degenerative lumbar joint disease and 2-a posterior dynamic stabilization system used to restabilize the spine after surgery for spinal stenosis, as an alternative to lumbar fusion
  • Unique, patented, activated collagen, CellerateRX(R) for the expanding diabetes and greater woundcare markets
  • Vital signs monitoring device for use as an early congestive heart failure (CHF) crisis indicator at home, to avoid acute/expensive hospitalizations
  • Whole-body imaging technology for orthopedic applications
  • Wireless, implantable heart device that allows Congestive Heart Failure (CHF) patients to monitor data using a handheld instrument
  • World' s smallest leg compression device for the prevention of deep vein thrombosis (DVT) in surgical patients, as a safe and effective alternative to Lovenox, for a significantly reduced price
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