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Worldwide Spine Surgery: Products, Technologies, Markets & Opportunities 2010-2020

This report is a detailed worldwide market and technology assessment and forecast of the products and technologies in the management of diseases and disorders of the spine as outlined in the following table of contents. The report describes the diseases and disorders of the spine, characterizing the patient populations, their current clinical management, and trends in clinical management as new techniques and technologies are expected to be developed and emerge.

This report details the currently available products and technologies, and the manufacturers offering them, for posterior pedicle screw fusion systems, anterior cervical plate systems, anterior thoraco-lumbar plate systems, anterior lumbar interbody fusion, transforaminal lumbar interbody fusion, posterior lumbar interbody fusion, axial lumbar interbody fusion, interspinous process spacer systems, cervical artificial discs, lumbar artificial discs, vertebroplasty, balloon kyphoplasty, allografts, demineralized bone matrices, and bone morphogenetic proteins.

The report details the products and technologies under development and markets for each in spine surgery. The report provides a current and ten-year forecast by region/country of procedures, unit sales, average selling price and manufacturer revenues for, specifically, Americas (USA, Canada, Mexico, Brazil), European Union (United Kingdom, Germany, France, Italy, Spain, Rest of Europe), Asia-Pacific (Japan, China, India, Australia/New Zealand) and Rest of World. The forecasts address product- and country-specific impacts in the market of new technologies through the coming decade. The report profiles 46 key companies in this industry, providing data on their current products, current market position and products under development.

Table of Contents

SECTION 1: CLINICAL BACKGROUND OF SPINAL DISEASE

  • 1.1. Spinal Anatomy
    • 1.1.1. Segments of the Spine
      • 1.1.1.1. Cervical Spine
      • 1.1.1.2. Thoracic Spine
      • 1.1.1.3. Lumbar Spine
      • 1.1.1.4. Sacrum and Sacroiliac Joint
    • 1.1.2. Intervertebral Discs
    • 1.1.3. Back Pain
    • 1.1.4. Measurement of Spine Pain: The Oswestry Scale
    • 1.1.5. Diagnosing the Causes of Back Pain
    • 1.1.6. The Use of Imaging in Spine Diagnostics
    • 1.1.7. Medical Management of Back Pain
  • 1.2. Mechanical and Degenerative Diseases of the Spine
    • 1.2.1. Mechanical Disorders of the Spine
      • 1.2.1.1. Modic Changes
      • 1.2.1.2. Myelopathy
    • 1.2.2. Degenerative Diseases
      • 1.2.2.1. Degenerative Disc Disease
      • 1.2.2.2. Facet Tropism
      • 1.2.2.3. Herniated Disc
      • 1.2.2.4. Spondylolysis
      • 1.2.2.5. Spondylolisthesis
      • 1.2.2.6. Spinal Stenosis
      • 1.2.2.7. Osteoporosis
      • 1.2.2.8. Osteophytes or Bone Spurs
    • 1.2.3. Epidemiology of Disc-Related Spinal Disease
    • 1.2.4. Treatment of Degenerative Disc Disease
  • 1.3. Congenital and Adult Spinal Deformities
    • 1.3.1. Scoliosis
      • 1.3.1.1. Congenital Scoliosis
      • 1.3.1.2. Neuromuscular Scoliosis
      • 1.3.1.3. Degenerative Scoliosis
      • 1.3.1.4. Idiopathic Scoliosis
      • 1.3.1.5. Epidemiology of Scoliosis
    • 1.3.2. Kyphosis
      • 1.3.2.1. Gibbus Deformity
      • 1.3.2.2. Scheuermann's Disease (Juvenile Kyphosis)
      • 1.3.2.3. Congenital Kyphosis
      • 1.3.2.4. Secondary Kyphosis
      • 1.3.2.5. Epidemiology of Kyphosis
    • 1.3.3. Lordosis
      • 1.3.3.1. Causes of Lordosis
      • 1.3.3.2. Epidemiology of Lordosis
    • 1.3.4. Ankylosing Spondylitis
      • 1.3.4.1. Diagnosing Spondylitis
      • 1.3.4.2. Epidemiology of Spondylitis
    • 1.3.5. Treatment of Congenital Disorders of the Spine
      • 1.3.5.1. Treatment of Scoliosis
      • 1.3.5.2. Treatment of Kyphosis
      • 1.3.5.3. Treatment of Lordosis
      • 1.3.5.4. Treatment of Ankylosing Spondylitis
  • 1.4. Autoimmune Diseases of the Spine
    • 1.4.1. Discitis
    • 1.4.2. Sacroiliitis
    • 1.4.3. Arachnoiditis
    • 1.4.4. Rheumatoid Arthritis
      • 1.4.4.1. Diagnosing Spinal Rheumatoid Arthritis
      • 1.4.4.2. Epidemiology of Rheumatoid Arthritis
    • 1.4.5. Osteoarthritis
      • 1.4.5.1. Diagnosing Osteoarthritis
      • 1.4.5.2. Spondylosis
      • 1.4.5.3. Epidemiology of Osteoarthritis
    • 1.4.6. Treatment of Autoimmune Spinal Disorders
  • 1.5. Spinal Tumors
    • 1.5.1. Benign Spinal Tumors
    • 1.5.2. Epidemiology of Spinal Tumors
    • 1.5.3. Treatment of Spinal Tumors
  • 1.6. Traumatic Spinal Injury
    • 1.6.1. Fracture Classification
    • 1.6.2. Cervical
    • 1.6.3. Thoracic
    • 1.6.4. Lumbar
    • 1.6.5. Vertebral Compression Factures (VCFs)
    • 1.6.6. Epidemiology of Spinal Injury
    • 1.6.7. Treatment of Traumatic Spinal Injury
  • 1.7. Costs Associated with Spinal Disorders and Treatment
  • 1.8. Drivers of Spine Disorders
    • 1.8.1. Aging Populations
      • 1.8.1.1. USA and Canada
      • 1.8.1.2. Latin America
      • 1.8.1.3. European Union
      • 1.8.1.4. Asia-Pacific (Japan, China, India, Australia)
    • 1.8.2. Obesity
      • 1.8.2.1. USA & Canada
      • 1.8.2.2. Latin America (Mexico, Brazil)
      • 1.8.2.3. European Union
      • 1.8.2.4. Asia-Pacific (Japan, China, India, Australia)
    • 1.8.3. Osteoporosis
      • 1.8.3.1. USA and Canada
      • 1.8.3.2. Latin America (Mexico, Brazil)
      • 1.8.3.3. European Union
      • 1.8.3.4. Asia-Pacific (Japan, China, India, Australia)

SECTION 2: SPINE SURGERY PROCEDURES AND DEVICES

  • 2.1. The Use of imaging in Spine Surgery
    • 2.1.1. Discography to Identify Painful Discs
    • 2.1.2. Endoscopic Spine Surgery
    • 2.1.3. Video-assisted Thoracic Surgery (VATS)
    • 2.1.4. Computer-assisted Spine Surgical (CASS) Navigation
    • 2.1.5. Cone-beam CT
      • 2.1.5.1. Medtronic's O-arm Surgical Imaging System
  • 2.2. Fusion, Fixation and Motion Preservation
    • 2.2.1. The Spine Patients Outcomes Research Trial (SPORT)
    • 2.2.2. Spinal Fusion Overview
      • 2.2.2.1. Requirements for Successful Spine Fusion
      • 2.2.2.2. implanting Cages with Built-in Lordosis
      • 2.2.2.3. Posterolateral and Interbody Fusion Surgery
      • 2.2.2.4. Autograft, Allograft or Bone Graft Substitutes in Fusion Surgery
    • 2.2.3. Cervical Spine Surgery
    • 2.2.4. Spinal Fixation
    • 2.2.5. Posterior Pedicle Screw Fusion Systems
    • 2.2.6. Anterior Cervical Plate (ACP) Systems
    • 2.2.7. Interspinous Process Spacers (ISP)
    • 2.2.8. Interbody Fusion Devices
      • 2.2.8.1. Anterior Lumbar Interbody Fusion (ALIF or TLIF)
      • 2.2.8.2. Posterior Lumbar Interbody Fusion (PLIF)
      • 2.2.8.3. Transforaminal Lumbar Interbody Fusion (TLIF)
      • 2.2.8.4. Extreme Lateral Lumbar Interbody Fusion (XLIF)
      • 2.2.8.5. TranS1's AxiaLIF
    • 2.2.9. Dynamic Stabilization Devices
    • 2.2.10. Emerging Fusion and Fixation Technologies
  • 2.3. Annulus repair
  • 2.4. Laminoplasty for Spinal Stenosis
  • 2.5. Anterior Cervical Discectomy and Fusion (ACDF)
  • 2.6. Discectomies and microdiscectomies
    • 2.6.1. Microdiscectomy
    • 2.6.2. Percutaneous endoscopic lumbar discectomy
  • 2.7. Artificial Disc Replacement (ADR)
    • 2.7.1. ACDF vs. Arthroplasty
    • 2.7.2. Success in Single and Multi-level Cervical Disc Replacement
    • 2.7.3. Nucleus Arthroplasty and Nucleus Disc Prostheses
    • 2.7.4. Intradiscal Annuloplasty Therapy
    • 2.7.5. Emerging Technologies
  • 2.8. Foraminotomy
  • 2.9. Corpectomy
  • 2.10. Vertebral Compression Fracture Treatment Technologies
    • 2.10.1. Vertebroplasty
      • 2.10.1.1. The Buchbinder Study
      • 2.10.1.2. The Kallmes Study
    • 2.10.2. Balloon Kyphoplasty
    • 2.10.3. Vertebroplasty Devices
    • 2.10.4. Balloon Kyphoplasty Devices
    • 2.10.5. Emerging Technologies
  • 2.11. Biologics
    • 2.11.1. Spinal Allografts
    • 2.11.2. Demineralized Bone Matrix (DBM)
    • 2.11.3. Bone Morphogenetic Proteins (rhBMP-2 and rhBMP-7)
      • 2.11.3.1. The Spine Journal, Infuse and Medtronic
    • 2.11.4. Emerging Biologics Technologies
      • 2.11.4.1. Stem Cells for Regenerating Spinal Anatomy
      • 2.11.4.2. Mesenchymal Stromal Cells for Treatment of DDD
      • 2.11.4.3. Disc Regeneration
      • 2.11.4.4. Biological Cements for Treating Spinal Fractures
  • 2.12. Materials Used in Spine Surgery Devices
    • 2.12.1. Desired Characteristics of Implant Materials
    • 2.12.2. PEEK
    • 2.12.3. Zimmer's Trabecular Metal Technology
    • 2.12.4. Emerging Technologies
      • 2.12.4.1. Bioresorbable Spinal Cages
  • 2.13. Other Emerging Spine Surgery Technologies
    • 2.13.1. Facet Joint Replacement
    • 2.13.2. Minimally Invasive Spine Surgery (MISS)
      • 2.13.2.1. Medtronic's MAST platform
      • 2.13.2.2. joimax's Transforaminal Endoscopic Surgical System
    • 2.13.3. The Use of Lasers in Spine Surgery
    • 2.13.4. Injectable Microgel Particles
    • 2.13.5. DFine's StabiliTR Vertebral Augmentation System for VCFs

SECTION 3: GLOBAL PROCEDURE VOLUMES, UNITS, AVERAGE SELLING PRICES AND MARKET FOR SPINE SURGERY DEVICES

  • 3.1. Global Markets by Product, 2010-2020
    • 3.1.1. Global Market for Posterior Pedicle Screw Fusion Systems
    • 3.1.2. Global Market for Anterior Cervical Plate (ACP) Systems
    • 3.1.3. Global Market for Anterior Thoraco-Lumbar Plate Systems
    • 3.1.4. Global Market for Interbody Fusion Devices
      • 3.1.4.1. Global Market for Anterior Lumbar Interbody Fusion (ALIF) Devices
      • 3.1.4.2. Global Market for Transforaminal Lumbar Interbody Fusion (TLIF) Devices
      • 3.1.4.3. Global Market for Posterior Lumbar Interbody Fusion (PLIF) Devices
      • 3.1.4.4. Global Market for Axial Lumbar Interbody Fusion (AxiaLIF) Devices
    • 3.1.5. Global Market for Interspinous Process Spacers (ISP)
    • 3.1.6. Global Market for Total Artificial Discs
      • 3.1.6.1. Global Market for Artificial Cervical Discs
      • 3.1.6.2. Global Market for Artificial Lumbar Discs
    • 3.1.7. Global Market for Vertebroplasty Devices
    • 3.1.8. Global Market for Balloon Kyphoplasty Devices
    • 3.1.9. Global Market for Total Spine Biologics
      • 3.1.9.1. Global Market for Spinal Allografts
      • 3.1.9.2. Global Market for Demineralized Bone Matrix (DBM)
      • 3.1.9.3. Global Market for Bone Morphogenetic Proteins
  • 3.2. Americas
    • 3.2.1. USA
      • 3.2.1.1. Reimbursement for spine surgery procedures
        • 3.2.1.1.1. TranS1's reimbursement strategy
      • 3.2.1.2. Denial of coverage for spine fusions for DDD
      • 3.2.1.3. Posterior Pedicle Screw Fusion Systems
      • 3.2.1.4. Anterior Cervical Plate (ACP) Systems
      • 3.2.1.5. Anterior Thoraco-Lumbar Plate Systems
      • 3.2.1.6. Total USA Interbody Fusion Market
        • 3.2.1.6.1. ALIF
        • 3.2.1.6.2. TLIF
        • 3.2.1.6.3. PLIF
        • 3.2.1.6.4. AxiaLIF
      • 3.2.1.7. Interspinous Process Spacers (ISP)
      • 3.2.1.8. USA Total Market for Artificial Discs
        • 3.2.1.8.1. Artificial Cervical Discs
        • 3.2.1.8.2. Artificial Lumbar Discs
      • 3.2.1.9. Vertebroplasty
      • 3.2.1.10. Balloon Kyphoplasty
      • 3.2.1.11. Total Spinal Biologics
        • 3.2.1.11.1. Allografts
        • 3.2.1.11.2. Demineralized Bone Matrix
        • 3.2.1.11.3. Bone Morphogenetic Proteins
    • 3.2.2. Canada
      • 3.2.2.1. Healthcare system and spine surgery procedures
      • 3.2.2.2. Posterior Pedicle Screw Fusion Systems
      • 3.2.2.3. Anterior Cervical Plate (ACP) Systems
      • 3.2.2.4. Anterior Thoraco-Lumbar Plate Systems
      • 3.2.2.5. Total Canada Interbody Fusion Market
        • 3.2.2.5.1. ALIF
        • 3.2.2.5.2. TLIF
        • 3.2.2.5.3. PLIF
        • 3.2.2.5.4. AxiaLIF
      • 3.2.2.6. Interspinous Process Spacers (ISP)
      • 3.2.2.7. Canada Market for Total Artificial Discs
        • 3.2.2.7.1. Artificial Cervical Discs
        • 3.2.2.7.2. Artificial Lumbar Discs
      • 3.2.2.8. Vertebroplasty
      • 3.2.2.9. Balloon Kyphoplasty
      • 3.2.2.10. Total Spinal Biologics
        • 3.2.2.10.1. Allografts
        • 3.2.2.10.2. Demineralized Bone Matrix
        • 3.2.2.10.3. Bone Morphogenetic Proteins
    • 3.2.3. Mexico
      • 3.2.3.1. Posterior Pedicle Screw Fusion Systems
      • 3.2.3.2. Anterior Cervical Plate (ACP) Systems
      • 3.2.3.3. Anterior Thoraco-Lumbar Plate Systems
      • 3.2.3.4. Total Mexico Interbody Fusion Devices
        • 3.2.3.4.1. ALIF
        • 3.2.3.4.2. TLIF
        • 3.2.3.4.3. PLIF
        • 3.2.3.4.4. AxiaLIF
      • 3.2.3.5. Interspinous Process Spacers (ISP)
      • 3.2.3.6. Mexico Market for Total Artificial Discs
        • 3.2.3.6.1. Artificial Cervical Discs
        • 3.2.3.6.2. Artificial Lumbar Discs
      • 3.2.3.7. Vertebroplasty
      • 3.2.3.8. Balloon Kyphoplasty
      • 3.2.3.9. Total Spinal Biologics
        • 3.2.3.9.1. Allografts
        • 3.2.3.9.2. Demineralized Bone Matrix
        • 3.2.3.9.3. Bone Morphogenetic Proteins
    • 3.2.4. Brazil
      • 3.2.4.1. Posterior Pedicle Screw Fusion Systems
      • 3.2.4.2. Anterior Cervical Plate (ACP) Systems
      • 3.2.4.3. Anterior Thoraco-Lumbar Plate Systems
      • 3.2.4.4. Total Brazil Interbody Fusion Market
        • 3.2.4.4.1. ALIF
        • 3.2.4.4.2. TLIF
        • 3.2.4.4.3. PLIF
        • 3.2.4.4.4. AxiaLIF
      • 3.2.4.5. Interspinous Process Spacers (ISP)
      • 3.2.4.6. Brazil Market for Total Artificial Discs
        • 3.2.4.6.1. Artificial Cervical Discs
        • 3.2.4.6.2. Artificial Lumbar Discs
      • 3.2.4.7. Vertebroplasty
      • 3.2.4.8. Balloon Kyphoplasty
      • 3.2.4.9. Total Spinal Biologics
        • 3.2.4.9.1. Allografts
        • 3.2.4.9.2. Demineralized Bone Matrix
        • 3.2.4.9.3. Bone Morphogenetic Proteins
  • 3.3. European Union
    • 3.3.1. EU Healthcare Coverage for Spine Procedures
    • 3.3.2. United Kingdom
      • 3.3.2.1. Posterior Pedicle Screw Fusion Systems
      • 3.3.2.2. Anterior Cervical Plate (ACP) Systems
      • 3.3.2.3. Anterior Thoraco-Lumbar Plate Systems
      • 3.3.2.4. Total United Kingdom Interbody Fusion Devices Market
        • 3.3.2.4.1. ALIF
        • 3.3.2.4.2. TLIF
        • 3.3.2.4.3. PLIF
        • 3.3.2.4.4. AxiaLIF
      • 3.3.2.5. Interspinous Process Spacers (ISP)
      • 3.3.2.6. United Kingdom Market for Total Artificial Discs
        • 3.3.2.6.1. Artificial Cervical Discs
        • 3.3.2.6.2. Artificial Lumbar Discs
      • 3.3.2.7. Vertebroplasty
      • 3.3.2.8. Balloon Kyphoplasty
      • 3.3.2.9. Total Spinal Biologics
        • 3.3.2.9.1. Allografts
        • 3.3.2.9.2. Demineralized Bone Matrix
        • 3.3.2.9.3. Bone Morphogenetic Proteins
    • 3.3.3. Germany
      • 3.3.3.1. Posterior Pedicle Screw Fusion Systems
      • 3.3.3.2. Anterior Cervical Plate (ACP) Systems
      • 3.3.3.3. Anterior Thoraco-Lumbar Plate Systems
      • 3.3.3.4. Total Germany Interbody Fusion Devices Market
        • 3.3.3.4.1. ALIF
        • 3.3.3.4.2. TLIF
        • 3.3.3.4.3. PLIF
        • 3.3.3.4.4. AxiaLIF
      • 3.3.3.5. Interspinous Process Spacers (ISP)
      • 3.3.3.6. Germany Market for Total Artificial Discs
        • 3.3.3.6.1. Artificial Cervical Discs
        • 3.3.3.6.2. Artificial Lumbar Discs
      • 3.3.3.7. Vertebroplasty
      • 3.3.3.8. Balloon Kyphoplasty
      • 3.3.3.9. Total Spinal Biologics
        • 3.3.3.9.1. Allografts
        • 3.3.3.9.2. Demineralized Bone Matrix
        • 3.3.3.9.3. Bone Morphogenetic Proteins
    • 3.3.4. France
      • 3.3.4.1. Posterior Pedicle Screw Fusion Systems
      • 3.3.4.2. Anterior Cervical Plate (ACP) Systems
      • 3.3.4.3. Anterior Thoraco-Lumbar Plate Systems
      • 3.3.4.4. Total France Interbody Fusion Devices Market
        • 3.3.4.4.1. ALIF
        • 3.3.4.4.2. TLIF
        • 3.3.4.4.3. PLIF
        • 3.3.4.4.4. AxiaLIF
      • 3.3.4.5. Interspinous Process Spacers (ISP)
      • 3.3.4.6. France Market for Total Artificial Discs
        • 3.3.4.6.1. Artificial Cervical Discs
        • 3.3.4.6.2. Artificial Lumbar Discs
      • 3.3.4.7. Vertebroplasty
      • 3.3.4.8. Balloon Kyphoplasty
      • 3.3.4.9. Total Spinal Biologics
        • 3.3.4.9.1. Allografts
        • 3.3.4.9.2. Demineralized Bone Matrix
        • 3.3.4.9.3. Bone Morphogenetic Proteins
    • 3.3.5. Spain
      • 3.3.5.1. Posterior Pedicle Screw Fusion Systems
      • 3.3.5.2. Anterior Cervical Plate (ACP) Systems
      • 3.3.5.3. Anterior Thoraco-Lumbar Plate Systems
      • 3.3.5.4. Total Spain Interbody Fusion Devices Market
        • 3.3.5.4.1. ALIF
        • 3.3.5.4.2. TLIF
        • 3.3.5.4.3. PLIF
        • 3.3.5.4.4. AxiaLIF
      • 3.3.5.5. Interspinous Process Spacers (ISP)
      • 3.3.5.6. Spain Market for Total Artificial Discs
        • 3.3.5.6.1. Artificial Cervical Discs
        • 3.3.5.6.2. Artificial Lumbar Discs
      • 3.3.5.7. Vertebroplasty
      • 3.3.5.8. Balloon Kyphoplasty
      • 3.3.5.9. Total Spinal Biologics
        • 3.3.5.9.1. Allografts
        • 3.3.5.9.2. Demineralized Bone Matrix
        • 3.3.5.9.3. Bone Morphogenetic Proteins
    • 3.3.6. Italy
      • 3.3.6.1. Posterior Pedicle Screw Fusion Systems
      • 3.3.6.2. Anterior Cervical Plate (ACP) Systems
      • 3.3.6.3. Anterior Thoraco-Lumbar Plate Systems
      • 3.3.6.4. Total Italy Interbody Fusion Devices Market
        • 3.3.6.4.1. ALIF
        • 3.3.6.4.2. TLIF
        • 3.3.6.4.3. PLIF
        • 3.3.6.4.4. AxiaLIF
      • 3.3.6.5. Interspinous Process Spacers (ISP)
      • 3.3.6.6. Italy Market for Total Artificial Discs
        • 3.3.6.6.1. Artificial Cervical Discs
        • 3.3.6.6.2. Artificial Lumbar Discs
      • 3.3.6.7. Vertebroplasty
      • 3.3.6.8. Balloon Kyphoplasty
      • 3.3.6.9. Total Spinal Biologics
        • 3.3.6.9.1. Allografts
        • 3.3.6.9.2. Demineralized Bone Matrix
        • 3.3.6.9.3. Bone Morphogenetic Proteins
    • 3.3.7. Rest of Europe
      • 3.3.7.1. Posterior Pedicle Screw Fusion Systems
      • 3.3.7.2. Anterior Cervical Plate (ACP) Systems
      • 3.3.7.3. Anterior Thoraco-Lumbar Plate Systems
      • 3.3.7.4. Total Rest of Europe Interbody Fusion Devices Market
        • 3.3.7.4.1. ALIF
        • 3.3.7.4.2. TLIF
        • 3.3.7.4.3. PLIF
        • 3.3.7.4.4. AxiaLIF
      • 3.3.7.5. Interspinous Process Spacers (ISP)
      • 3.3.7.6. Rest of Europe Market for Total Artificial Discs
        • 3.3.7.6.1. Artificial Cervical Discs
        • 3.3.7.6.2. Artificial Lumbar Discs
      • 3.3.7.7. Vertebroplasty
      • 3.3.7.8. Balloon Kyphoplasty
      • 3.3.7.9. Total Spinal Biologics
        • 3.3.7.9.1. Allografts
        • 3.3.7.9.2. Demineralized Bone Matrix
        • 3.3.7.9.3. Bone Morphogenetic Proteins
  • 3.4. Asia-Pacific
    • 3.4.1. Japan
      • 3.4.1.1. Posterior Pedicle Screw Fusion Systems
      • 3.4.1.2. Anterior Cervical Plate (ACP) Systems
      • 3.4.1.3. Anterior Thoraco-Lumbar Plate Systems
      • 3.4.1.4. Total Japan Interbody Fusion Devices Market
        • 3.4.1.4.1. ALIF
        • 3.4.1.4.2. TLIF
        • 3.4.1.4.3. PLIF
        • 3.4.1.4.4. AxiaLIF
      • 3.4.1.5. Interspinous Process Spacers (ISP)
      • 3.4.1.6. Japan Market for Total Artificial Discs
        • 3.4.1.6.1. Artificial Cervical Discs
        • 3.4.1.6.2. Artificial Lumbar Discs
      • 3.4.1.7. Vertebroplasty
      • 3.4.1.8. Balloon Kyphoplasty
      • 3.4.1.9. Total Spinal Biologics
        • 3.4.1.9.1. Allografts
        • 3.4.1.9.2. Demineralized Bone Matrix
        • 3.4.1.9.3. Bone Morphogenetic Proteins
    • 3.4.2. China
      • 3.4.2.1. Posterior Pedicle Screw Fusion Systems
      • 3.4.2.2. Anterior Cervical Plate (ACP) Systems
      • 3.4.2.3. Anterior Thoraco-Lumbar Plate Systems
      • 3.4.2.4. Total China Interbody Fusion Devices Market
        • 3.4.2.4.1. ALIF
        • 3.4.2.4.2. TLIF
        • 3.4.2.4.3. PLIF
        • 3.4.2.4.4. AxiaLIF
      • 3.4.2.5. Interspinous Process Spacers (ISP)
      • 3.4.2.6. China Market for Total Artificial Discs
        • 3.4.2.6.1. Artificial Cervical Discs
        • 3.4.2.6.2. Artificial Lumbar Discs
      • 3.4.2.7. Vertebroplasty
      • 3.4.2.8. Balloon Kyphoplasty
      • 3.4.2.9. Total Spinal Biologics
        • 3.4.2.9.1. Allografts
        • 3.4.2.9.2. Demineralized Bone Matrix
        • 3.4.2.9.3. Bone Morphogenetic Proteins
    • 3.4.3. India
      • 3.4.3.1. Posterior Pedicle Screw Fusion Systems
      • 3.4.3.2. Anterior Cervical Plate (ACP) Systems
      • 3.4.3.3. Anterior Thoraco-Lumbar Plate Systems
      • 3.4.3.4. Total India Interbody Fusion Devices Market
        • 3.4.3.4.1. ALIF
        • 3.4.3.4.2. TLIF
        • 3.4.3.4.3. PLIF
        • 3.4.3.4.4. AxiaLIF
      • 3.4.3.5. Interspinous Process Spacers (ISP)
      • 3.4.3.6. India Market for Total Artificial Discs
        • 3.4.3.6.1. Artificial Cervical Discs
        • 3.4.3.6.2. Artificial Lumbar Discs
      • 3.4.3.7. Vertebroplasty
      • 3.4.3.8. Balloon Kyphoplasty
      • 3.4.3.9. Total Spinal Biologics
        • 3.4.3.9.1. Allografts
        • 3.4.3.9.2. Demineralized Bone Matrix
        • 3.4.3.9.3. Bone Morphogenetic Proteins
    • 3.4.4. Australia/New Zealand
      • 3.4.4.1. Posterior Pedicle Screw Fusion Systems
      • 3.4.4.2. Anterior Cervical Plate (ACP) Systems
      • 3.4.4.3. Anterior Thoraco-Lumbar Plate Systems
      • 3.4.4.4. Total Australia/New Zealand Interbody Fusion Devices Market
        • 3.4.4.4.1. ALIF
        • 3.4.4.4.2. TLIF
        • 3.4.4.4.3. PLIF
        • 3.4.4.4.4. AxiaLIF
      • 3.4.4.5. Interspinous Process Spacers (ISP)
      • 3.4.4.6. Australia Market for Total Artificial Discs
        • 3.4.4.6.1. Artificial Cervical Discs
        • 3.4.4.6.2. Artificial Lumbar Discs
      • 3.4.4.7. Vertebroplasty
      • 3.4.4.8. Balloon Kyphoplasty
      • 3.4.4.9. Total Spinal Biologics
        • 3.4.4.9.1. Allografts
        • 3.4.4.9.2. Demineralized Bone Matrix
        • 3.4.4.9.3. Bone Morphogenetic Proteins
  • 3.5. Rest of World
    • 3.5.1. Posterior Pedicle Screw Fusion Systems
    • 3.5.2. Anterior Cervical Plate (ACP) Systems
    • 3.5.3. Anterior Thoraco-Lumbar Plate Systems
    • 3.5.4. Total Rest of World Interbody Fusion Devices Market
      • 3.5.4.1. ALIF
      • 3.5.4.2. TLIF
      • 3.5.4.3. PLIF
      • 3.5.4.4. AxiaLIF
    • 3.5.5. Interspinous Process Spacers (ISP)
    • 3.5.6. Rest of World Market for Total Artificial Discs
      • 3.5.6.1. Artificial Cervical Discs
      • 3.5.6.2. Artificial Lumbar Discs
    • 3.5.7. Vertebroplasty
    • 3.5.8. Balloon Kyphoplasty
    • 3.5.9. Total Spinal Biologics
      • 3.5.9.1. Allografts
      • 3.5.9.2. Demineralized Bone Matrix
      • 3.5.9.3. Bone Morphogenetic Proteins

SECTIONS 4: CLINICAL TRIALS IN THE TREATMENT OF SPINAL DISORDERS

  • 4.1. Aesculap Implant Systems (Aesculap USA)
  • 4.2. Alphatec Spine
  • 4.3. Anulex Technologies, Inc.
  • 4.4. Apatech, Inc.
  • 4.5. Baxano, Inc.
  • 4.6. Benvenue Medical
  • 4.7. Biomet, Inc.
  • 4.8. BioSET (BioSurface Engineering Technologies, Inc)
  • 4.9. CeraPedics, Inc.
  • 4.10. CrossTrees Medical
  • 4.11. DFine, Inc.
  • 4.12. DePuy Spine
  • 4.13. Exactech
  • 4.14. Facet Solutions, Inc.
  • 4.15. Impliant, Ltd.
  • 4.16. Interventional Spine, Inc
  • 4.17. LDR Spine USA
  • 4.18. Medicrea USA
  • 4.19. Medtronic Spinal and Biologics
  • 4.20. Mesoblast, Ltd.
  • 4.21. NuVasive
  • 4.22. Orthofix, Inc.
  • 4.23. Pioneer Surgical Technologies, Inc.
  • 4.24. Ranier Technology Ltd.
  • 4.25. SpinalMotion, Inc.
  • 4.26. Synthes USA Products, LLC
  • 4.27. VertiFlex, Inc.
  • 4.28. Vertos Medical
  • 4.29. Zimmer

SECTION 5: COMPANY PROFILES

  • 5.1. Aesculap USA (B. Braun)
  • 5.2. Alphatec Spine Inc.
  • 5.3. Amedica/US Spine
  • 5.4. ArthroCare Corp.
  • 5.5. AxioMed
  • 5.6. Benvenue Medical
  • 5.7. Binder Biomedical, Inc.
  • 5.8. Biomet Spine
  • 5.9. Cardo Medical Inc.
  • 5.10. CareFusion
  • 5.11. Centinel Spine, Inc.
  • 5.12. DePuy Spine, Inc.
  • 5.13. Dfine, Inc.
  • 5.14. Exactech, Inc.
  • 5.15. Globus Medical, Inc.
  • 5.16. Integra LifeSciences
  • 5.17. Interventional Spine, Inc.
  • 5.18. Intrinsic Therapeutics, Inc.
  • 5.19. joimax GmbH
  • 5.20. K2M, Inc
  • 5.21. LDR Medical
  • 5.22. Life Spine
  • 5.23. Mazor Robotics Ltd.
  • 5.24. Medtronic/Medtronic Spinal & Biologics
  • 5.25. NuVasive, Inc.
  • 5.26. Olympus Biotech
  • 5.27. Ortho Development Corporation
  • 5.28. Orthofix International N.V.
  • 5.29. Paradigm Spine, LLC
  • 5.30. Pioneer Surgical Technology
  • 5.31. SI-Bone, Inc.
  • 5.32. Smith & Nephew
  • 5.33. Spinal Kinetics
  • 5.34. SpinalMotion, Inc.
  • 5.35. SpineSmith
  • 5.36. SpineVision SA
  • 5.37. Spine Wave, Inc.
  • 5.38. Stryker Corp.
  • 5.39. Synthes Inc.
  • 5.40. Titan Spine, LLC
  • 5.41. TranS1
  • 5.42. Vertebral Technologies, Inc.
  • 5.43. VertiFlex
  • 5.44. Wright Medical Technology, Inc.
  • 5.45. X-Spine Systems, Inc.
  • 5.46. Zimmer Holdings/Zimmer Spine

Appendix - Company Directory

List of Exhibits

  • Exhibit 1-1: Anatomy of the Spinal Column
  • Exhibit 1-2: Human Spine Structure Showing Vertebrae, Intervertebral Discs, and Spinal Cord
  • Exhibit 1-3: Components of the Human Spine
  • Exhibit 1-4: Cervical Spine Injuries and Potential Related Impairments
  • Exhibit 1-5: Clinical Features - Radiculopathy by Spinal Level
  • Exhibit 1-6: The Oswestry Disability Questionnaire, v2.1a
  • Exhibit 1-7: Mechanical Disorders of the Spine
  • Exhibit 1-8: Degenerative Diseases of the Spine
  • Exhibit 1-9: Location, Effects, and Incidence of Major Lumbar Disc Herniations
  • Exhibit 1-10: Grades of Spondylolisthesis
  • Exhibit 1-11: Estimated Annual Number of Fractures Due to Osteoporosis in the U.S.
  • Exhibit 1-12: Potential Limitations of Traditional Lower Lumbar Spine Procedures
  • Exhibit 1-13: Congenital Disorders of the Spine
  • Exhibit 1-14: Inflammatory and Infectious Diseases of the Spine
  • Exhibit 1-15: Tumors of the Spine
  • Exhibit 1-16: Causes of Trauma to Spinal Regions
  • Exhibit 1-17: Summary of Total, Direct and Indirect Costs of LBP in a Variety of Domestic and International Study Populations
  • Exhibit 1-18: Number & Percentage of Global Population over Age 65, 2000 - 2050 (Population in 000s)
  • Exhibit 1-19: U.S. Census Figures and Projections, Ages 65 and Up, 1900-2050
  • Exhibit 1-20: Number & Percentage of U.S. Population over Age 65, 1910 - 2050
  • Exhibit 1-21: Population of Selected Latin American Countries over Age 65, by Percentage, 1960 - 2050
  • Exhibit 1-22: Number of People 65 & Older in Selected Latin American Countries, 1960 - 2050 (000s)
  • Exhibit 1-23: EU Population & Percentage of Population over Age 65, 2010 - 2050 (Populations in 000s)
  • Exhibit 1-24: Percentage of Asia-Pacific Population Over Age 65, 1950 - 2050
  • Exhibit 1-25: Number & Percentage of Obese in Global Population (Population in 000s)
  • Exhibit 1-26: Number & Percentage of Obese in USA & Canada Population (Population in 000s)
  • Exhibit 1-27: Number & Percentage of Obese in Latin American Population (Population in 000s)
  • Exhibit 1-28: Number & Percentage of Obese in EU Population (Population in 000s)
  • Exhibit 1-29: Number & Percentage of Obese in Asia-Pacific Population (Population in 000s)
  • Exhibit 1-30: Projected Number of Osteoporosis Fractures Worldwide (000s)
  • Exhibit 1-31: Incidence Rates of Hip Fractures Among Population aged 50 and Over by Sex in OECD Countries (Rate Per 100,000)
  • Exhibit 1-32: Hip Fracture Cases in Mexico, 2009-2050
  • Exhibit 2-1: Selected Companies, Products and Regulatory Status in Spine Fusion and Fixation
  • Exhibit 2-2: Companies, Products and Regulatory Status in the Facet Replacement Market
  • Exhibit 2-3: Companies, Products and Regulatory Status in ACP Systems Space
  • Exhibit 2-4: Companies, Products and Regulatory Status in Anterior Thoraco-Lumbar Plate Systems Space
  • Exhibit 2-5: Companies, Products and Regulatory Status in the Interspinous Process Space
  • Exhibit 2-6: Companies, Products and Regulatory Status in the Interbody System Space
  • Exhibit 2-7: Companies, Products and Regulatory Status in the Dynamic Stabilization Space
  • Exhibit 2-8: Estimated global forecast for number of lumbar discectomy procedures and revisions, 2010-2020.
  • Exhibit 2-9: Global Number of Discectomy Procedures by Region, 2010-2020
  • Exhibit 2-10: Companies, Products and Regulatory Status in Cervical Artificial Disc Space
  • Exhibit 2-11: Companies, Products and Regulatory Status in the Lumbar Artificial Disc Space
  • Exhibit 2-12: Companies, Products and Regulatory Status in the Nucleus Replacement Market
  • Exhibit 2-13: Companies, Products and Regulatory Status in Vertebroplasty and Kyphoplasty
  • Exhibit 2-14: Companies, Products and Regulatory Status of Spinal Allografts
  • Exhibit 2-15: Companies, Products and Regulatory Status of Demineralized Bone Matrix (DBM)
  • Exhibit 2-16: Companies, Products and Regulatory Status in Bone Morphogenetic Proteins
  • Exhibit 3-1: Global Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-2: Global Market Shares, Spine Surgery Devices, 2010
  • Exhibit 3-3: Global Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-4: Global Market Shares for Posterior Pedicle Screw Fusion Systems, 2010
  • Exhibit 3-5: Global Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-6: Global Market Shares for Anterior Cervical Plate Systems, 2010
  • Exhibit 3-7: Global Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-8: Global Market Shares for Anterior Thoraco-Lumbar Plate Systems, 2010
  • Exhibit 3-9: Total Global Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-10: Global Market for Anterior Lumbar Interbody Fusion (ALIF) Devices, 2010-2020 (USD Millions)
  • Exhibit 3-11: Global Market Shares for Anterior Lumbar Interbody Fusion Devices, 2010
  • Exhibit 3-12: Global Market for Transforaminal Lumbar Interbody Fusion (TLIF) Devices, 2010-2020 (USD Millions)
  • Exhibit 3-13: Global Market Shares for Transforaminal Interbody Fusion Devices, 2010
  • Exhibit 3-14: Global Market for Posterior Lumbar Interbody Fusion (PLIF) Devices, 2010-2020 (USD Millions)
  • Exhibit 3-15: Global Market Shares for Posterior Lumbar Interbody Fusion Devices, 2010
  • Exhibit 3-16: Global Market for Axial Lumbar Interbody Fusion (AxiaLIF) Device, 2010-2020 (USD Millions)
  • Exhibit 3-17: Global Market for Interspinous Process Spacers (ISP), 2010-2020 (USD Millions)
  • Exhibit 3-18: Global Market Shares for Interspinous Process Spacer Devices, 2010
  • Exhibit 3-19: Global Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-20: Global Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-21: Global Market Shares for Artificial Cervical Discs, 2010
  • Exhibit 3-22: Global Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-23: Global Market Shares for Artificial Lumbar Discs, 2010
  • Exhibit 3-24: Global Market for Vertebroplasty Devices, 2010-2020 (USD Millions)
  • Exhibit 3-25: Global Market Shares for Vertebroplasty Devices, 2010
  • Exhibit 3-26: Global Market for Balloon Kyphoplasty Devices, 2010-2020 (USD Millions)
  • Exhibit 3-27: Global Market Shares for Balloon Kyphoplasty Devices, 2010
  • Exhibit 3-28: Global Market for Total Spine Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-29: Global Market for Spinal Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-30: Global Market Shares for Spinal Allografts, 2010
  • Exhibit 3-31: Global Market for Demineralized Bone Matrix (DBM), 2010-2020 (USD Millions)
  • Exhibit 3-32: Global Market Shares for Demineralized Bone Matrix (DBM), 2010
  • Exhibit 3-33: Global Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-34: Global Market Shares for Bone Morphogenetic Proteins (BMP) for Spine Surgery, 2010
  • Exhibit 3-35: Americas Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-36: USA Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-37: USA Spine Market Segments as Percents of the Total USA Spine Surgery Device Market, 2010
  • Exhibit 3-38: USA Spine Market Segments as Percents of the Total USA Spine Surgery Device Market, 2020
  • Exhibit 3-39: USA Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-40: USA Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-41: USA Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-42: Total USA Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-43: USA Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-44: USA Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-45: USA Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-46: USA Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-47: USA Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-48: USA Total Market for Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-49: USA Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-50: USA Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-51: USA Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-52: USA Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-53: USA Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-54: USA Market for Allografts, 2010-2020
  • Exhibit 3-55: USA Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-56: USA Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-57: Canada Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-58: Canada Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-59: Canada Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-60: Canada Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-61: Total Canada Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-62: Canada Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-63: Canada Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-64: Canada Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-65: Canada Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-66: Canada Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-67: Canada Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-68: Canada Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-69: Canada Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-70: Canada Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-71: Canada Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-72: Canada Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-73: Canada Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-74: Canada Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-75: Canada Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-76: Mexico Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-77: Mexico Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-78: Mexico Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-79: Mexico Market for Anterior Thoraco-Lumbar Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-80: Total Mexico Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-81: Mexico Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-82: Mexico Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-83: Mexico Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-84: Mexico Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-85: Mexico Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-86: Mexico Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-87: Mexico Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-88: Mexico Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-89: Mexico Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-90: Mexico Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-91: Mexico Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-92: Mexico Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-93: Mexico Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-94: Mexico Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-95: Brazil Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-96: Brazil Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-97: Brazil Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-98: Brazil Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-99: Total Brazil Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-100: Brazil Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-101: Brazil Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-102: Brazil Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-103: Brazil Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-104: Brazil Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-105: Brazil Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-106: Brazil Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-107: Brazil Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-108: Brazil Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-109: Brazil Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-110: Brazil Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-111: Brazil Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-112: Brazil Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-113: Brazil Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-114: European Union Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-115: United Kingdom Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-116: United Kingdom Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-117: United Kingdom Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-118: United Kingdom Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-119: Total United Kingdom Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-120: United Kingdom Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-121: United Kingdom Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-122: United Kingdom Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-123: United Kingdom Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-124: United Kingdom Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-125: United Kingdom Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-126: United Kingdom Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-127: United Kingdom Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-128: United Kingdom Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-129: United Kingdom Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-130: United Kingdom Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-131: United Kingdom Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-132: United Kingdom Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-133: United Kingdom Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-134: Germany Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-135: Germany Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-136: Germany Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-137: Germany Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-138: Total Germany Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-139: Germany Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-140: Germany Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-141: Germany Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-142: Germany Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-143: Germany Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-144: Germany Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-145: Germany Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-146: Germany Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-147: Germany Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-148: Germany Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-149: Germany Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-150: Germany Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-151: Germany Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-152: Germany Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-153: France Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-154: France Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-155: France Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-156: France Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-157: Total France Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-158: France Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-159: France Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-160: France Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-161: France Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-162: France Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-163: France Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-164: France Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-165: France Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-166: France Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-167: France Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-168: France Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-169: France Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-170: France Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-171: France Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-172: Spain Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-173: Spain Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-174: Spain Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-175: Spain Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-176: Total Spain Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-177: Spain Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-178: Spain Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-179: Spain Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-180: Spain Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-181: Spain Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-182: Spain Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-183: Spain Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-184: Spain Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-185: Spain Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-186: Spain Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-187: Spain Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-188: Spain Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-189: Spain Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-190: Spain Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-191: Italy Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-192: Italy Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-193: Italy Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-194: Italy Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-195: Total Italy Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-196: Italy Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-197: Italy Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-198: Italy Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-199: Italy Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-200: Italy Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-201: Italy Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-202: Italy Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-203: Italy Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-204: Italy Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-205: Italy Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-206: Italy Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-207: Italy Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-208: Italy Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-209: Italy Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-210: Rest of Europe Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-211: Rest of Europe Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-212: Rest of Europe Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-213: Rest of Europe Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-214: Total Rest of Europe Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-215: Rest of Europe Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-216: Rest of Europe Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-217: Rest of Europe Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-218: Rest of Europe Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-219: Rest of Europe Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-220: Rest of Europe Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-221: Rest of Europe Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-222: Rest of Europe Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-223: Rest of Europe Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-224: Rest of Europe Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-225: Rest of Europe Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-226: Rest of Europe Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-227: Rest of Europe Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-228: Rest of Europe Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-229: Asia-Pacific Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-230: Japan Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-231: Japan Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-232: Japan Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-233: Japan Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-234: Total Japan Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-235: Japan Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-236: Japan Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-237: Japan Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-238: Japan Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-239: Japan Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-240: Japan Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-241: Japan Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-242: Japan Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-243: Japan Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-244: Japan Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-245: Japan Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-246: Japan Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-247: Japan Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-248: Japan Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-249: China Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-250: China Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-251: China Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-252: China Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-253: Total China Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-254: China Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-255: China Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-256: China Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-257: China Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-258: China Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-259: China Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-260: China Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-261: China Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-262: China Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-263: China Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-264: China Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-265: China Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-266: China Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-267: China Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-268: India Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-269: India Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-270: India Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-271: India Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-272: Total India Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-273: India Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-274: India Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-275: India Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-276: India Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-277: India Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-278: India Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-279: India Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-280: India Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-281: India Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-282: India Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-283: India Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-284: India Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-285: India Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-286: India Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-287: Australia/NZ Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-288: Australia/NZ Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-289: Australia/NZ Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-290: Australia/NZ Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-291: Total Australia/NZ Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-292: Australia/NZ Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-293: Australia/NZ Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-294: Australia/NZ Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-295: Australia/NZ Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-296: Australia/NZ Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-297: Australia Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-298: Australia/NZ Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-299: Australia/NZ Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-300: Australia/NZ Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-301: Australia/NZ Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-302: Australia/NZ Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-303: Australia/NZ Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-304: Australia/NZ Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-305: Australia/NZ Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
  • Exhibit 3-306: Rest of World Market for Spine Surgery Devices, 2010-2020 (USD Millions)
  • Exhibit 3-307: Rest of World Market for Posterior Pedicle Screw Fusion Systems, 2010-2020 (USD Millions)
  • Exhibit 3-308: Rest of World Market for Anterior Cervical Plate (ACP) Systems, 2010-2020 (USD Millions)
  • Exhibit 3-309: Rest of World Market for Anterior Thoraco-Lumbar Plate Systems, 2010-2020 (USD Millions)
  • Exhibit 3-310: Total Rest of World Market for Interbody Fusion Devices, 2010-2020 (USD Millions)
  • Exhibit 3-311: Rest of World Market for ALIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-312: Rest of World Market for TLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-313: Rest of World Market for PLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-314: Rest of World Market for AxiaLIF Devices, 2010-2020 (USD Millions)
  • Exhibit 3-315: Rest of World Market for Interspinous Process Spacers, 2010-2020 (USD Millions)
  • Exhibit 3-316: Rest of World Market for Total Artificial Discs, 2010-2020 (USD Millions)
  • Exhibit 3-317: Rest of World Market for Artificial Cervical Discs, 2010-2020 (USD Millions)
  • Exhibit 3-318: Rest of World Market for Artificial Lumbar Discs, 2010-2020 (USD Millions)
  • Exhibit 3-319: Rest of World Market for Vertebroplasty, 2010-2020 (USD Millions)
  • Exhibit 3-320: Rest of World Market for Balloon Kyphoplasty, 2010-2020 (USD Millions)
  • Exhibit 3-321: Rest of World Market for Total Spinal Biologics, 2010-2020 (USD Millions)
  • Exhibit 3-322: Rest of World Market for Allografts, 2010-2020 (USD Millions)
  • Exhibit 3-323: Rest of World Market for Demineralized Bone Matrix, 2010-2020 (USD Millions)
  • Exhibit 3-324: Rest of World Market for Bone Morphogenetic Proteins, 2010-2020 (USD Millions)
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