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Worldwide Surgical Sealants, Glues and Wound Closure Markets 2013-2018

This Report details the complete range of sealants & glues technologies used in traumatic, surgical and other wound closure, including tapes, sutures/staples/mechanical closure, hemostats, fibrin sealants/glues and medical adhesives. The report details current clinical and technology developments, with data on products in development (detailing market status) and on the market; market size and forecast; competitor market shares; competitor profiles; and market opportunity. The Report provides full year actual data from 2013 and, for available companies, quarterly data from 2014. The report provides a worldwide forecast to 2018 of the markets for these technologies, with particular emphasis on the market impact of new technologies through the forecast period. The report provides specific forecasts and shares of the worldwide market by segment for Americas (detail for U.S., Rest of North America and Latin America), Europe (detail for United Kingdom, German, France, Italy, Spain, Rest of Europe), Asia/Pacific (detail for Japan, Korea, Rest of Asia/Pacific) and Rest of World.

The report also provides background data on the surgical, disease and traumatic wound patient populations targeted by current technologies and those under development, and the current clinical practices in the management of these patients, including the dynamics among the various clinical specialties or subspecialties vying for patient population and facilitating or limiting the growth of technologies.

The Report establishes the current worldwide market size for major technology segments as a baseline for and projecting growth in the market through 2018. The report also assesses and projects the composition of the market as technologies gain or lose relative market performance over this period.

The report profiles the top companies by revenue and a reasonable selection of the most promising or otherwise noteworthy companies in the markets covered in this report, providing data on their current products, current market position and products under development.

Table of Contents

Executive Summary

Section 1: Clinical Need, Caseload and Procedure Volume

  • 1.1. Anatomy and Physiology of Tissue Repair
  • 1.2. The Skin
  • 1.3. Internal Tissues and Organ
  • 1.4. Wound Classification and Types
    • 1.4.1. Classification by Morphology and Severity
    • 1.4.2. Classification by Cause
    • 1.4.3. Classification by Type of Surgical Wound
    • 1.4.4. Estimated Prevalence of Major Wound Types
    • 1.4.5. Surgical Wounds and Wound Closure
  • 1.5. Caseload
    • 1.5.1. Cardiovascular
      • 1.5.1.1. Coronary Heart Disease
      • 1.5.1.2. Dysfunctional Heart Valves
      • 1.5.1.3. Peripheral Vascular Disorders
      • 1.5.1.4. Abnormal Aortic Aneurysms
      • 1.5.1.5. Drivers of Caseloads for Cardiac Surgery
    • 1.5.2. Neurological
      • 1.5.2.1. Stroke
      • 1.5.2.2. Parkinson's Disease
      • 1.5.2.3. Epilepsy
      • 1.5.2.4. Traumatic Injury
      • 1.5.2.5. Peripheral Nerve Treatment
      • 1.5.2.6. Neurology Drivers
    • 1.5.3. Orthopedic
      • 1.5.3.1. Hip Replacements
      • 1.5.3.2. Knee Replacements
      • 1.5.3.3. Cartilage Repair
      • 1.5.3.4. Ligament Damage
      • 1.5.3.5. Bone Grafting
      • 1.5.3.6. Vertebral Disc Repair
      • 1.5.3.7. Drivers of Orthopedic Surgery
    • 1.5.4. Urological
      • 1.5.4.1. Incontinence
      • 1.5.4.2. Drivers of Urological Surgery
    • 1.5.5. Skin
      • 1.5.5.1. Burns
      • 1.5.5.2. Pressure Ulcers
      • 1.5.5.3. Diabetic Ulcers
      • 1.5.5.4. Venous Ulcers
      • 1.5.5.5. Plastic Surgery
  • 1.6. The Role of Modern Sealant, Securement and Hemostatic Products in Surgery
    • 1.6.1. Surgical Sealants
    • 1.6.2. Cyanoacrylates
    • 1.6.3. Market Outlook: Surgical Sealants and Glues
    • 1.6.4. High9Strength Sealants and Glues

Section 2: SCIENCE, TECHNOLOGY, DEVELOPMENT, CLINICAL AND REGULATORY CHALLENGES

  • 2.1. Tissue Healing
    • 2.1.1. Hemostasis
    • 2.1.2. Proliferation and Maturation
    • 2.1.3. Factors That Affect Healing
  • 2.2. Product Development
    • 2.2.1. Development Timelines
    • 2.2.2. Collagen and Thrombin Combination
    • 2.2.3. Polyethylene Glycol Polymer (PEG)
    • 2.2.4. Albumin Cross9Linked with Glutaraldehyde
    • 2.2.5. Delivery Systems
  • 2.3. Cost9Effectiveness
  • 2.4. Regulatory Challenges
    • 2.4.1. Approval Processes
    • 2.4.2. History of Product Development
    • 2.4.3. Regulatory Aspects

Section 3: Products, Technologies, and Forecast Opportunities

  • 3.1. Overview
  • 3.2. Market Overview
  • 3.3. Development Timeline
  • 3.4. Sutures and Staples
    • 3.4.1. Leading Suture and Staple Competitors and Products
      • 3.4.1.1. Johnson & Johnson/Ethicon
      • 3.4.1.2. Covidien
    • 3.4.2. Additional Competitors
      • 3.4.2.1. B. Braun/Aesculap
      • 3.4.2.2. Teleflex Medical
      • 3.4.2.3. Advanced Medical Solutions Group
      • 3.4.2.4. Angiotech Pharmaceuticals
    • 3.4.3. Start9Ups and Novel Technologies
      • 3.4.3.1. VitaThreads LLC
      • 3.4.3.2. JustRight Surgical LLC
      • 3.4.3.3. ZSX Medical
    • 3.4.4. Staple9 and Suture9line Buttressing Products
    • 3.4.5. Sutures and Staples Market Analysis and Forecast
  • 3.5. Vascular Closure Devices, External Compression, and Hemostat Products for Interventional Procedures
    • 3.5.1. Market Leaders in Vascular Closure Devices
      • 3.5.1.1. St. Jude Medical
      • 3.5.1.2. Abbott Vascular
    • 3.5.2. Other Competitors
      • 3.5.2.1.1. Access Closure/Cardinal Health
      • 3.5.2.1.2. Cordis/J&J
      • 3.5.2.1.3. Cardiva)Medical
      • 3.5.2.1.4. Innovasa
      • 3.5.2.1.5. Morris)Innovative
      • 3.5.2.1.6. Vascular)Solutions,)Inc.
    • 3.5.3. Start9Ups and Emerging Technologies in the Vascular Closure Device Space
      • 3.5.3.1.1. VivaSure Medical
      • 3.5.3.1.2. Vascular Closure Systems
      • 3.5.3.1.3. Transluminal Technologies
      • 3.5.3.1.4. InSeal Medical
      • 3.5.3.1.5. Arstasis
    • 3.5.4. Vascular Closure Device Market Analysis and Global Forecast
  • 3.6. Surgical Sealants, Glues, and Hemostats
    • 3.6.1. Sealant Types
      • 3.6.1.1. Biologically Active Surgical Sealants, Products and Companies
      • 3.6.1.2. Synthetic Surgical Sealants and Glues, Products and Companies
      • 3.6.1.3. Nonactive Hemostats: Scaffolds, Patches, Sponges, Putties, Powders, and Matrices
    • 3.6.2. Market Leaders in the Surgical Sealants, Glues, and Hemostats Market
      • 3.6.2.1. Ethicon/J&J
      • 3.6.2.2. Baxter International
      • 3.6.2.3. CR Bard
      • 3.6.2.4. CryoLife
      • 3.6.2.5. Other Leading Competitors
      • 3.6.2.5.1. CSL Behring
      • 3.6.2.5.2. Pfizer
      • 3.6.2.5.3. Asahi Kasei Medical
    • 3.6.3. Emerging Competitors and Products in Development
      • 3.6.3.1. Sealants and Glues
        • 3.6.3.1.1. Teijin Pharma Ltd./Teijin Group
        • 3.6.3.1.2. The Medicines Company
        • 3.6.3.1.3. Integra LifeSciences
        • 3.6.3.1.4. Hyperbranch Medical Technology
        • 3.6.3.1.5. Endomedix
        • 3.6.3.1.6. Ocular Therapeutix
        • 3.6.3.1.7. Cohera Medical
      • 3.6.3.2. Start9Ups and Emerging Competitors in Surgical Sealants, Glues, and Hemostats
        • 3.6.3.2.1. Gecko Biomedical
        • 3.6.3.2.2. Arch Therapeutics
        • 3.6.3.2.3. Medical Adhesive Revolution
        • 3.6.3.2.4. Sealantis
        • 3.6.3.2.5. Xcede Technologies
        • 3.6.3.2.6. LifeBond
      • 3.6.3.3. Hemostat Market
        • 3.6.3.3.1. Abyrx Inc.
        • 3.6.3.3.2. RevMedX Inc.
        • 3.6.3.3.3. HemCon Medical Technologies
        • 3.6.3.3.4. Chitogen Inc.
    • 3.6.4. Sealants, Glues, and Hemostats: Market Analysis and Global Forecasts
      • 3.6.4.1. Surgical Sealants and Glues
    • 3.6.5. Hemostats
  • 3.7. External Wound/Skin Closure Devices
    • 3.7.1. High9Strength Glues for External Skin Closure
      • 3.7.1.1. Market Leaders in the Cyanoacrylate Glue Space: B. Braun and Ethicon
      • 3.7.1.2. Additional Competitors in the External Glue Market
        • 3.7.1.2.1. Advanced Medical Solutions Group PLC
        • 3.7.1.2.2. GluStitch
        • 3.7.1.2.3. Adhezion Biomedical
        • 3.7.1.2.4. Chemence Medical Products
    • 3.7.2. External Skin Staplers, Tapes, and Strips
      • 3.7.2.1. Absorbable Subcutaneous Staple Products
        • 3.7.2.1.1. Incisive Surgical Inc.
        • 3.7.2.1.2. Surgimatix Inc.
      • 3.7.2.2. Novel Suture and Staple Alternatives and Adjunctive Technologies
        • 3.7.2.2.1. ZipLine Medical Inc.
        • 3.7.2.2.2. Canica Design Inc.
      • 3.7.2.3. Leading Competitors in Medical Tapes and Strips
      • 3.7.2.4. Medical Tapes and Strips: Market Analysis
    • 3.7.3. Medical Tape Market Forecast
  • 3.8. Surgical Sealants, Glues, and Wound Closure Markets by Country and Segment: Global and Regional Analysis
    • 3.8.1. Americas
      • 3.8.1.1. United States
        • 3.8.1.1.1. Sutures and Staples
        • 3.8.1.1.2. Vascular Closure Devices
        • 3.8.1.1.3. Tapes
        • 3.8.1.1.4. Surgical Hemostats
        • 3.8.1.1.5. Surgical Sealants and Glues
      • 3.8.1.2. Rest of North America
      • 3.8.1.3. Latin America
        • 3.8.1.3.1. Sutures and Staples
        • 3.8.1.3.2. Vascular Closure Devices
        • 3.8.1.3.3. Tapes
        • 3.8.1.3.4. Hemostats
        • 3.8.1.3.5. Surgical Sealants and Glues
    • 3.8.2. European Union
      • 3.8.2.1. United Kingdom
        • 3.8.2.1.1. Sutures and Staples
        • 3.8.2.1.2. Vascular Closure Devices
        • 3.8.2.1.3. Tapes
        • 3.8.2.1.4. Surgical Hemostats
        • 3.8.2.1.5. Surgical Sealants and Glues
      • 3.8.2.2. Germany
        • 3.8.2.2.1. Sutures and Staples
        • 3.8.2.2.2. Vascular Closure Devices
        • 3.8.2.2.3. Tapes
        • 3.8.2.2.4. Surgical Hemostats
        • 3.8.2.2.5. Surgical Sealants and Glues
      • 3.8.2.3. France
        • 3.8.2.3.1. Sutures and Staples
        • 3.8.2.3.2. Vascular Closure Devices
        • 3.8.2.3.3. Tapes
        • 3.8.2.3.4. Surgical Hemostats
        • 3.8.2.3.5. Surgical Sealants and Glues
      • 3.8.2.4. Spain
        • 3.8.2.4.1. Sutures and Staples
        • 3.8.2.4.2. Vascular Closure Devices
        • 3.8.2.4.3. Surgical Tapes
        • 3.8.2.4.4. Surgical Hemostats
        • 3.8.2.4.5. Surgical Sealants and Glues
      • 3.8.2.5. Italy
        • 3.8.2.5.1. Sutures and Staples
        • 3.8.2.5.2. Vascular Closure Devices
        • 3.8.2.5.3. Surgical Tapes
        • 3.8.2.5.4. Surgical Hemostats
        • 3.8.2.5.5. Surgical Sealants and Glues
      • 3.8.2.6. Rest of Europe
        • 3.8.2.6.1. Sutures and Staples
        • 3.8.2.6.2. Vascular Closure Devices
        • 3.8.2.6.3. Surgical Tapes
        • 3.8.2.6.4. Surgical Hemostats
        • 3.8.2.6.5. Surgical Sealants and Glues
    • 3.8.3. Asia Pacific
      • 3.8.3.1. Japan
        • 3.8.3.1.1. Sutures and Staples
        • 3.8.3.1.2. Vascular Closure Devices
        • 3.8.3.1.3. Surgical Tapes
        • 3.8.3.1.4. Surgical Hemostats
        • 3.8.3.1.5. Surgical Sealants and Glues
      • 3.8.3.2. Korea
        • 3.8.3.2.1. Sutures and Staples
        • 3.8.3.2.2. Vascular Closure Devices
        • 3.8.3.2.3. Surgical Tapes
        • 3.8.3.2.4. Surgical Hemostats
        • 3.8.3.2.5. Surgical Sealants and Glues
      • 3.8.3.3. Rest of Asia Pacific
        • 3.8.3.3.1. Sutures and Staples
        • 3.8.3.3.2. Vascular Closure Devices
        • 3.8.3.3.3. Surgical Tapes
        • 3.8.3.3.4. Surgical Hemostats
        • 3.8.3.3.5. Surgical Sealants and Glues
    • 3.8.4. Rest of World
      • 3.8.4.1. Sutures and Staples
      • 3.8.4.2. Vascular Closure Devices
      • 3.8.4.3. Surgical Tapes
      • 3.8.4.4. Surgical Hemostats
      • 3.8.4.5. Surgical Sealants and Glues

Section 4: Company Profiles

  • 4.1. 3M
  • 4.2. Abbott Laboratories
  • 4.3. Abyrx Inc.
  • 4.4. AccessClosure, Inc./Cardinal Health
  • 4.5. Actamax Surgical Materials LLC
  • 4.6. Adhesives Research, Inc.
  • 4.7. Adhezion Biomedical, LLC
  • 4.8. Advanced Medical Solutions Group plc/Medlogic Global
  • 4.9. Advanced Vascular Dynamics
  • 4.10. Angiotech Pharmaceuticals, Inc./Surgical Specialities Corporation
  • 4.11. Arch Therapeutics
  • 4.12. Asahi Kasei Medical
  • 4.13. Aso LLC
  • 4.14. Aspen Surgical Products
  • 4.15. Avery Dennison
  • 4.16. B. Braun (Braun Melsungen AG)/Aesculap
  • 4.17. Baxter International Inc.
  • 4.18. Beeken BioMedical, LLC
  • 4.19. Bernsco Surgical Supply (George Tiemann & Co.)
  • 4.20. Biocoral Inc.
  • 4.21. Bioster a.s.
  • 4.22. Biotronik SE & Co., KG
  • 4.23. BSN Medical
  • 4.24. CR Bard (Bard Medical, Davol)
  • 4.25. Canica Design, Inc.
  • 4.26. Cardiva Medical, Inc.
  • 4.27. Celox Medical, Inc.
  • 4.28. Ceremed, Inc.
  • 4.29. Chemence Medical
  • 4.30. Chesson Laboratory Associates, Inc.
  • 4.31. Cohera Medical, Inc.
  • 4.32. ConMed, Inc.
  • 4.33. Cordis Corporation (JNJ)
  • 4.34. Covidien Ltd.
  • 4.35. CryoLife Inc.
  • 4.36. CSIRO PhotoMedical Technologies
  • 4.37. CSL Behring
  • 4.38. CuraMedical BV
  • 4.39. Derma Sciences, Inc.
  • 4.40. Dynamic Techno Medicals Pvt. Ltd.
  • 4.41. Entegrion, Inc.
  • 4.42. Equimedical B.V.
  • 4.43. Ferndale Laboratories
  • 4.44. FibroGen, Inc.
  • 4.45. Gecko Biomedical
  • 4.46. Gelita Medical BV
  • 4.47. GEM srl
  • 4.48. GluStitch, Inc.
  • 4.49. Graceduty Company Limited
  • 4.50. Hartmann Group/Hartmann USA
  • 4.51. HemCon Medical Technologies, Inc.
  • 4.52. Hemostasis, LLC
  • 4.53. HyperBranch Medical Technology, Inc.
  • 4.54. Hy9Tape International
  • 4.55. Incisive Surgical, Inc.
  • 4.56. Innovasa Corporation
  • 4.57. Integra Lifesciences Corporation
  • 4.58. Johnson & Johnson (Ethicon, Inc., Ethicon Endo9Surgery, Inc., Ethicon Biosurgery)
  • 4.59. Kaketsuken (Chemo9Sero9Therapeutic Research Institute)
  • 4.60. Kensey Nash Corporation
  • 4.61. Kimberly9Clark Health Care
  • 4.62. Kookbo Chemicals Co., Ltd. (KB Chem.)
  • 4.63. Kuros Biosurgery AG
  • 4.64. Laboratoires Urgo (Urgo Medical)
  • 4.65. LifeBond Ltd.
  • 4.66. LifeScience PLUS
  • 4.67. Lohmann & Rauscher
  • 4.68. Marine Polymer Technologies, Inc.
  • 4.69. Medafor, Inc./CR Bard
  • 4.70. Medical Adhesive Revolution
  • 4.71. MedTrade Products, Ltd.
  • 4.72. Meyer9Haake GmbH Medical Innovations
  • 4.73. Mölnlycke Health Care AB
  • 4.74. Morris Innovative
  • 4.75. Motex Healthcare Corp.
  • 4.76. NeatStitch Ltd.
  • 4.77. Neomend, Inc./CR Bard
  • 4.78. Nycomed (Takeda)
  • 4.79. Ocular Therapeutix, Inc.
  • 4.80. Opocrin S.p.A
  • 4.81. Orthovita, Inc./Stryker
  • 4.82. Pfizer Inc.
  • 4.83. Pluromed, Inc./Sanofi
  • 4.84. Ranfac Corporation
  • 4.85. RevMedX Inc.
  • 4.86. Resorba Wundversorgung GmbH & Co. KG/Advanced Medical Solutions Group
  • 4.87. Scion Cardio9Vascular, Inc.
  • 4.88. Sealantis
  • 4.89. Sea Run Holdings
  • 4.90. St. Jude Medical
  • 4.91. Starch Medical, Inc.
  • 4.92. STB Lifesaving Technologies, Inc.
  • 4.93. Teleflex Medical
  • 4.94. The Medicines Company
  • 4.95. TissueSeal, LLC
  • 4.96. Tissuemed Ltd.
  • 4.97. Vascular Solutions, Inc.
  • 4.98. Vivostat A/S
  • 4.99. Wortham Laboratories, Inc.
  • 4.100. Wound Care Technologies, Inc.
  • 4.101. Xcede Technologies
  • 4.102. Z9Medica Corporation
  • 4.103. ZipLine Medical Inc.
  • 4.104. ZymoGenetics, Inc./Bristol9Myers Squibb

List of Exhibits

  • Exhibit ES-1: Estimated Prevalence of Various Wound Types, 2011
  • Exhibit ES-2: Factors That Affect Wound Healing
  • Exhibit ES-3: Global Market Shares, Surgical Wound Closure Products, 2013
  • Exhibit ES-4: Worldwide Surgical Wound Closure Products Market, by Device Segment, 2013
  • Exhibit ES-5: Worldwide Surgical Wound Closure Products Market, by Device Segment, 2018
  • Exhibit ES-6: Global Market for Surgical Wound Closure Products, 2012-2018 (USD Millions)
  • Exhibit ES-7: Global Shares ofSurgical Wound Closure Products, by Region, 2012:
  • Exhibit ES-8: Global Shares ofSurgical Wound Closure Products, by Region, 2018:
  • Exhibit 1-1: Skin Structure Illustrating Major Organelles and Skin Layers
  • Exhibit 1-2: Classification of Wounds by Morphology
  • Exhibit 1-3: Severity Classification of Wounds
  • Exhibit 1-4: Wound Classification by Etiology
  • Exhibit 1-5: Surgical Wound Classification
  • Exhibit 1-6: Estimated Prevalence of Various Wound Types, 2011
  • Exhibit 1-7: The Coagulation Cascade
  • Exhibit 1-8: Criteria for Adjunctive Use of Hemostats, Sealants, Glues and Adhesion Prevention Products in Surgery
  • Exhibit 1-9: Surgical Procedures with Potential for the Use of Hemostats, Sealants, Glues and Wound Closure Products, Worldwide (Millions), 2014
  • Exhibit 1-10: Descriptions of Surgical Procedures Categories Benefitting from Closure and Securement Products
  • Exhibit 1-11: Prevalence of Common Cardiovascular Diseases, 2011 (000)
  • Exhibit 1-12: Potential for Neurological Applications, Prevalence of Applicable Disorders (000s), 2011
  • Exhibit 1-13: Potential for Orthopedic Applications, Frequency of Major Surgical Interventions (000), 2011
  • Exhibit 1-14: Potential for Urological Applications, Prevalence of Applicable Disorders (000), 2011
  • Exhibit 1-15: Potential for Dermal Repair, Prevalence of Applicable Disorders (000), 2011
  • Exhibit 1-16: Applications of Fibrin and Other Sealants
  • Exhibit 1-17: Surgical Procedures Using Fibrin and Other Sealant Products
  • Exhibit 1-18: Surgical Indications for High-Strength Glues
  • Exhibit 2-1: Factors That Affect Wound Healing
  • Exhibit 2-2: Timescales for Development of Closure and Sealant Products
  • Exhibit 2-3: Variables Associated With Clinical Evaluation of Closure and Securement and Related Products
  • Exhibit 3-1: Global Market Shares, Surgical Wound Closure Products, 2013
  • Exhibit 3-2: Global Market for Surgical Wound Closure Products, 2012-2018 (USD Millions)
  • Exhibit 3-3: Worldwide Market Forecast for Sutures and Surgical Stapling Devices, 2013-2018, USD Million
  • Exhibit 3-4: Worldwide Market Shares, Suture and Stapler Market, 2013
  • Exhibit 3-5: Selected Small- and Large-Bore Vascular Closure Devices
  • Exhibit 3-6: Selected External Compression Devices and Hemostat Pads for Interventional Procedures
  • Exhibit 3-7: Vascular Closure Device Worldwide Market Forecast, 2012-2018
  • Exhibit 3-8: Worldwide Vascular Closure Device Market, Share by Supplier, 2014
  • Exhibit 3-9: Selected Sealants, Glues, and Hemostats Containing Biologically Active Agents
  • Exhibit 3-10: Selected Nonactive Synthetic Surgical Sealants and Glues
  • Exhibit 3-11: Selected Nonactive Hemostatic Scaffolds, Patches, Sponges, Putties, Powders, and Matrices
  • Exhibit 3-12: Characteristics of the Ideal Hemostatic Dressing
  • Exhibit 3-13: Surgical Sealants and Glues Worldwide Market Forecast, 2012-2018
  • Exhibit 3-14: Global Surgical Sealants Market, Share by Supplier, 2013
  • Exhibit 3-15: Hemostats Worldwide Market Forecast, 2012-2018
  • Exhibit 3-16: Hemostats, Global Market Shares, 2013
  • Exhibit 3-17: Select Competitors in the High Strength Medical Adhesives Market
  • Exhibit 3-18: Select Competitors in the Medical Tapes and Strips Market
  • Exhibit 3-19: Surgical Tapes Worldwide Market Forecast, 2012-2018
  • Exhibit 3-20: Market Shares of Leading Competitors, Surgical Tapes, 2013
  • Exhibit 3-21: Worldwide Surgical Wound Closure Products Market, by Device Segment, 2013
  • Exhibit 3-22: Worldwide Surgical Wound Closure Products Market, by Device Segment, 2018
  • Exhibit 3-23: Global Market for Surgical Wound Closure Products, 2012-2018 (USD Millions)
  • Exhibit 3-24: Surgical Sealants, Glues, and Wound Closure Markets, the Americas, 2012-2018 (USD Millions)
  • Exhibit 3-25: Surgical Sealants, Glues, and Wound Closure Markets, United States, 2012-2018 (USD Millions)
  • Exhibit 3-26: USA Market for Sutures and Staples, 2012-2018 (Millions USD)
  • Exhibit 3-27: USA Market for Vascular Closure Devices, 2012-2018 (Millions USD)
  • Exhibit 3-28: USA Market for Tapes, 2012-2018 (Millions USD)
  • Exhibit 3-29: USA Market for Surgical Hemostats, 2012-2018 (Millions USD)
  • Exhibit 3-30: USA Market for Surgical Sealants and Glues, 2012-2018 (Millions USD)
  • Exhibit 3-31: Surgical Sealants, Glues, and Wound Closure Markets, Rest of North America (Canada and Mexico), 2012-2018 (USD Millions)
  • Exhibit 3-32: Surgical Sealants, Glues, and Wound Closure Markets, Latin America, 2012-2018 (USD Millions)
  • Exhibit 3-33: Latin America Market for Sutures and Staples, 2012-2018 (Millions USD)
  • Exhibit 3-34: Latin America Market for Vascular Closure Devices, 2012-2018 (Millions USD)
  • Exhibit 3-35: Latin America Market for Tapes, 2012-2018 (Millions USD)
  • Exhibit 3-36: Latin America Market for Hemostats, 2012-2018 (Millions USD)
  • Exhibit 3-37: Latin America Market for Surgical Sealants and Glues, 2012-2018 (Millions USD)
  • Exhibit 3-38: Surgical Wound Closure Product Markets, European Union, 2012-2018 (USD Millions)
  • Exhibit 3-39: Surgical Wound Closure Product Markets, United Kingdom, 2012-2018 (USD Millions)
  • Exhibit 3-40: United Kingdom Market for Sutures and Staples, 2012-2018 (Millions USD)
  • Exhibit 3-41: United Kingdom Market for Vascular Closure Devices, 2012-2018 (Millions USD)
  • Exhibit 3-42: United Kingdom Market for Tapes, 2012-2018 (Millions USD)
  • Exhibit 3-43: United Kingdom Market for Hemostats, 2012-2018 (Millions USD)
  • Exhibit 3-44: UK Market for Fibrin and Other Sealants, 2012-2018 (USD Millions)
  • Exhibit 3-45: Surgical Wound Closure Product Markets, Germany, 2012-2018 (USD Millions)
  • Exhibit 3-46: Germany Market for Sutures and Staples, 2012-2018 (USD Millions)
  • Exhibit 3-47: Germany Market for Vascular Closure Devices, 2012-2018 (USD Millions)
  • Exhibit 3-48: Germany Market for Surgical Tapes, 2012-2018 (USD Millions)
  • Exhibit 3-49: Germany Market for Surgical Hemostats, 2012-2018 (Millions USD)
  • Exhibit 3-50: Germany Market for Surgical Sealants and Glues, 2012-2018 (Millions USD)
  • Exhibit 3-51: Surgical Wound Closure Markets, France, 2012-2018 (USD Millions)
  • Exhibit 3-52: France Market for Sutures and Staples, 2012-2018 (USD Millions)
  • Exhibit 3-68: France Market for Vascular Closure Devices, 2012-2018 (USD Millions)
  • Exhibit 3-53: France Market for Tapes, 2012-2018 (USD Millions)
  • Exhibit 3-54: France Market for Surgical Hemostats, 2012-2018 (Millions USD)
  • Exhibit 3-55: France Market for Surgical Sealants and Glues, 2012-2018 (USD Millions)
  • Exhibit 3-56: Surgical Surgical Wound Closure Products Market, Spain, 2012-2018 (USD Millions)
  • Exhibit 3-57: Spain Market for Sutures and Staples, 2012-2018 (USD Millions)
  • Exhibit 3-58: Spain Market for Vascular Closure Devices, 2012-2018 (USD Millions)
  • Exhibit 3-59: Spain Market for Tapes, 2012-2018 (USD Millions)
  • Exhibit 3-60: Spain Market for Hemostats, 2012-2018 (Millions USD)
  • Exhibit 3-61: Spain Market for Surgical Sealants and Glues, 2013-2018 (USD Millions)
  • Exhibit 3-62: Surgical Wound Closure Markets, Italy, 2012-2018 (USD Millions)
  • Exhibit 3-63: Italy Market for Sutures and Staples, 2012-2018 (USD Millions)
  • Exhibit 3-64: Italy Market for Mechanical Closure Devices, 2010-2017 (USD Millions)
  • Exhibit 3-65: Italy Market for Surgical Tapes, 2012-2018 (USD Millions)
  • Exhibit 3-66: Italy Market for Surgical Hemostats, 2012-2018 (Millions USD)
  • Exhibit 3-67: Italy Market for Surgical Sealants and Glues, 2012-2018 (USD Millions)
  • Exhibit 3-68: Surgical Wound Closure Markets, Rest of Europe, 2012-2018 (USD Millions)
  • Exhibit 3-69: Rest of Europe Market for Sutures and Staples, 2012-2018 (USD Millions)
  • Exhibit 3-70: Rest of Europe Market for Vascular Closure Devices, 2012-2018 (USD Millions)
  • Exhibit 3-71: Rest of Europe Market for Surgical Tapes, 2012-2018 (USD Millions)
  • Exhibit 3-72: Rest of Europe Market for Hemostats, 2012-2018 (Millions USD)
  • Exhibit 3-73: Rest of Europe Market Surgical Sealants and Glues, 2012-2018 (USD Millions)
  • Exhibit 3-74: Surgical Wound Closure Product Markets, Asia Pacific, 2012-2018 (USD Millions)
  • Exhibit 3-75: Surgical Sealants, Glues, and Wound Closure Markets, Japan, 2012-2018 (USD Millions)
  • Exhibit 3-76: Japan Market for Sutures and Staples, 2012-2018 (USD Millions)
  • Exhibit 3-77: Exhibit 3-101: Japan Market for Vascular Closure Devices, 2012-2018 (USD Millions)
  • Exhibit 3-78: Japan Market for Tapes, 2012-2018 (USD Millions)
  • Exhibit 3-79: Japan Market for Hemostats, 2012-2018 (Millions USD)
  • Exhibit 3-80: Japan Market for Surgical Sealants and Glues, 2012-2018 (USD Millions)
  • Exhibit 3-81: Surgical Sealants, Glues, and Wound Closure Markets, Korea 2012-2018 (USD Millions)
  • Exhibit 3-82: Korea Market for Sutures and Staples, 2012-2018 (USD Millions)
  • Exhibit 3-83: Korea Market for Mechanical Closure Devices, 2012-2018 (USD Millions)
  • Exhibit 3-84: Korea Market for Tapes, 2012-2018 (USD Millions)
  • Exhibit 3-85: Korea Market for Surgical Hemostats, 2012-2018 (Millions USD)
  • Exhibit 3-86: Korea Market for Surgical Sealants and Glues, 2012-2018 (USD Millions)
  • Exhibit 3-87: Surgical Wound Closure Product Markets, Rest of Asia Pacific 2012-2018 (USD Millions)
  • Exhibit 3-88: Rest of Asia Pacific Market for Sutures and Staples, 2012-2018 (USD Millions)
  • Exhibit 3-89: Rest of Asia Pacific Market for Vascular Closure Devices, 2012-2018 (USD Millions)
  • Exhibit 3-90: Rest of Asia Pacific Market for Surgical Tapes, 2012-2018 (USD Millions)
  • Exhibit 3-91: Exhibit 3-119: Rest of Asia Pacific Market for Surgical Hemostats, 2012-2018 (Millions USD)
  • Exhibit 3-92: Rest of Asia Pacific Market for Surgical Sealants and Glues 2012-2018 (USD Millions)
  • Exhibit 3-93: Surgical Sealants, Glues, and Wound Closure Markets, Rest of World, 2012-2018 (USD Millions)
  • Exhibit 3-94: Rest of World Market for Sutures and Staples, 2012-2018 (USD Millions)
  • Exhibit 3-95: Rest of World Market for Vascular Closure Devices, 2012-2018 (USD Millions)
  • Exhibit 3-96: Rest of World Market for Tapes, 2012-2018 (USD Millions)
  • Exhibit 3-98: Rest of World Market for Surgical Sealants and Glues, 2013-2018 (USD Millions)
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