The European surgical hemostat, internal tissue sealant, and adhesion barrier
market remains both dynamic and vastly underpenetrated across the region in
2011 and is heavily influenced by numerous competing factors that will
contribute to overall revenue growth. Procedures in which these products are
most commonly used - cardiovascular and reconstructive procedures - will
continue to be driven by favorable demographics, leading to increased
procedure volumes. Procedure increases in this space will, however, be
hindered somewhat due to the increased usage of alternative low-cost treatment
options for controlling blood flow, sealing tissue, and preventing the
formation of adhesions postoperatively. Cost-consciousness among facilities in
Europe will continue to restrict revenue expansion and will be the primary
limiting factor. This fiscal restraint will cause physicians to limit their
usage of these devices, slowing device penetration in each segment to some
extent. The use of public tenders and group purchasing organizations will
cause declines in average selling prices (ASPs), limiting growth in the
European surgical hemostat, internal tissue sealant, and adhesion barrier
market. Despite these negative trends, the needs of physicians continue to go
unmet by the current product offerings; products in this space provide
benefits beyond their initial cost, which has helped these markets garner
increased attention from hospitals and physicians. With the continued
development of intuitive, technologically advanced products in all three
segments, current market players continue to jockey for position by increasing
procedural applicability for existing products while performing clinical
trials to further the boundaries of their new products. Positive clinical data
along with increased penetration by these devices across all three segments
will help to expand the European surgical hemostat, internal tissue sealant,
and adhesion barrier market through 2016.
METHODOLOGY
RESEARCH METHODOLOGY
This report uses a number of methodologies to gather and present data and
analysis. At the outset, a large survey of secondary sources is conducted.
These sources act as the basis for the primary research stage, which builds
and enhances the quantitative and qualitative attributes of the early research.
Secondary sources include:
government publications, such as documentation from securities
commissions, health care and statistical agencies, and regulatory and patent
authorities;
material provided by medical technology companies, including annual
reports, product brochures, and corporate profiles;
internal databases and reports, including previous reports on similar or
related topics; and
general Internet searches, medical literature, and newspaper and magazine
searches to identify various centers of specialization and articles that might
provide leads for primary research.
The secondary research stage builds the foundation for the primary research.
The primary research methodology has four steps:
Step 1: The first step involves an impartial scan of all the
information gathered during the secondary research stage to determine its
utility based on the specific requirements of this report. Each piece of
information is either discarded or marked as high- or low-priority and then
organized appropriately as determined by the structure and sectioning of the
report.
Step 2: At this stage, early assumptions are formed as to the
implications of the information for the various market segments. These
assumptions are then used to determine hypotheses using both inductive and
deductive approaches. On the quantitative front, these hypotheses result in
full historical and projected market data sets (market sizes - unit sales,
ASPs, and revenues - as well as market shares).
Step 3: At this stage, the research is in position for its most
important primary phase - expert interviews. Throughout the secondary research
phase, industry and medical experts are identified. These experts are then
contacted by telephone and asked to participate in interviews on recent trends
and developments in the industry. Interviews are either conducted at the time
of the initial call or scheduled at the convenience of the expert. Interview
questions are tailored to the expertise of each particular interviewee,
although in most cases, the most important questions are asked of all experts.
The questions are largely based on the assumptions and hypotheses developed in
Step 2, which are then augmented, discarded, or adjusted based on the views
and positions put forth. Attempts are made, whenever possible, to cross-check
the views of various experts against each other and to reach positions of
consensus on issues and market numbers.
In some cases, a sample of relevant physicians is surveyed or interviewed.
Physicians are asked to comment on various issues and trends, both in their
own practice and in the overall market. The responses provided are then used
to strengthen or augment the assumptions and hypotheses developed during the
primary research phase.
Step 4: The final stage of primary research involves individual and
group analysis by Millennium Research Group. All research results are assessed
and cross-checked thoroughly to determine their validity, relevance, and
weight. From this process, qualitative conclusions are reached and data points
finalized.
MARKETRACK METHODOLOGY
Millennium Research Group's Marketrack methodology involves recruiting
hospital personnel responsible for the management of medical equipment and
procedures to participate by providing procedure volumes, device usage data,
and brand-level pricing information on an ongoing basis. Hospital respondents
include facility managers, nurses, administrators, and physicians. Information
is generally collected on a quarterly basis and includes, but is not limited
to, numbers and types of procedures performed and devices used.
FORECAST METHODOLOGY
In addition to the research methodology outlined above, the following
"bottom-up" methodology is used to develop forecast assumptions for the report.
A comprehensive breakdown of various procedures and device unit sales is
prepared using data from several sources, including professional associations,
government statistics, and private research/media sources. Industry experts
and practitioners are consulted to ensure accuracy and verify observed trends.
As a cross-check, total industry revenues available through annual reports and
other sources are compared against modeled industry revenues.
Using the best estimates of industry experts, practitioners, private
research/media sources, and inhouse experts, year-by-year growth rates and
ASPs are applied individually to each subcategory to derive forecasts. These
estimates are cross-checked by industry experts (marketing managers, product
managers, company executives, etc.) and further refined.
Overall findings are compared against market and procedure forecasts published
by other sources to ensure reasonable estimates.
Companies mentioned in this report:
Aesculap
Anika Therapeutics
Baxter
B. Braun
BioCer
Covidien
CryoLife
DePuy
Ethicon
Ferrosan
FzioMed
Genzyme
HyperBranch Medical Technology
Innocoll
Johnson & Johnson
Medafor
Medtronic
Neomend
Nycomed
OMRIX biopharmaceuticals
Orthovita
Pfizer
Stryker
Table of Contents
Table of Contents
TABLE OF CONTENTS
LIST OF FIGURES AND TABLES
EXECUTIVE SUMMARY
1. COUNTRY OVERVIEWS
1.1. France
1.1.1. Demographics and Economy
1.1.2. Health Care System
1.1.3. Regulatory Environment
1.2. Germany
1.2.1. Demographics and Economy
1.2.2. Health Care System
1.2.3. Regulatory Environment
1.3. Italy
1.3.1. Demographics and Economy
1.3.2. Health Care System
1.3.3. Regulatory Environment
1.4. UK
1.4.1. Demographics and Economy
1.4.2. Health Care System
1.4.3. Regulatory Environment
1.5. European Manufacturing and Distribution
2. CLINICAL LANDSCAPE
2.1. Background
2.2. Procedure Descriptions
2.2.1. Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Procedures
5. SURGICAL HEMOSTAT, INTERNAL TISSUE SEALANT, AND ADHESION BARRIER MARKET
5.1. Market Snapshot
5.2. Detailed Market Analysis
5.3. Competitive Snapshot
5.4. Detailed Competitive Landscape
5.5. Market Shares
5.6. Recent Events
5.7. Most Promising Emerging Products
6. SURGICAL HEMOSTAT MARKET
6.1. Market Snapshot
6.2. Detailed Market Analysis
6.2.1. By Material (Qualitative Discussion Only)
6.3. Competitive Snapshot
6.4. Market Shares
7. INTERNAL TISSUE SEALANT MARKET
7.1. Market Snapshot
7.2. Detailed Market Analysis
7.2.1. Fibrin Sealants
7.2.2. Synthetic Sealants
7.2.3. Protein Sealants
7.3. Competitive Snapshot
7.4. Market Shares
8. ADHESION BARRIER MARKET
8.1. Market Snapshot
8.2. Detailed Market Analysis
8.3. Competitive Snapshot
8.4. Market Shares
APPENDIX: METHODOLOGY
APPENDIX: ACRONYMS AND INITIALISMS
APPENDIX: BIBLIOGRAPHY
LIST OF FIGURES AND TABLES
TABLE OF CONTENTS
LIST OF FIGURES AND TABLES
EXECUTIVE SUMMARY
Figure 1: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, Europe (USD), 2010 - 2016
Table 1: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market Landscape, Europe (USD), 2011 and 2016
Table 2: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market Leaders, by Product Type and Revenue, Europe, 2011
Table 3: Companies Mentioned
Table 4: Factors Impacting the Surgical Hemostat, Internal Tissue Sealant,
and Adhesion Barrier Market, by Product Type, Europe, 2011 - 2016
Table 5: Recent Novel Devices in the Surgical Hemostat, Internal Tissue
Sealant, and Adhesion Barrier Market, 2011
Table 6: Expected Key Events in the Surgical Hemostat, Internal Tissue
Sealant, and Adhesion Barrier Market, Europe, 2012 - 2016
Table 7: Geographies Covered, Europe
Table 8: Average Currency Exchange Rates
Table 9: Products Covered, Europe
1. COUNTRY OVERVIEWS
Table 10: Key Health and Economic Indicators, France
Table 11: Key Health and Economic Indicators, Germany
Table 12: Key Health and Economic Indicators, Italy
Table 13: Key Health and Economic Indicators, UK
2. CLINICAL LANDSCAPE
Table 14: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Procedures, by Application and Procedure Type
Table 15: Competing Treatments for Surgical Hemostats, Internal Tissue
Sealants, and Adhesion Barriers
3 PRODUCTS
Table 16: Surgical Hemostats, by Product Type and Material
Table 17: Advantages and Disadvantages of Surgical Hemostats, by Material
Table 18: Advantages and Disadvantages of Internal Tissue Sealants, by
Material
Table 19: Advantages and Disadvantages of Adhesion Barriers, by Product
Type
4. CLINICAL TRIALS
Table 20: Summary of Oxiplex US Pivotal Study
Table 21: Summary of The Fibrin Pad Liver Study
Table 22: Summary of the Efficiency of Intercoat (Oxiplex/AP Gel) in
Decreasing Intrauterine Adhesions
Table 23: Summary of the Prospective Evaluation of Vitagel for Reduction
in Blood Loss and Pain Following Unilateral TKA
Table 24: Summary of ESSCALIVER
Table 25: Summary of COBBANA
Table 26: Summary of Seprafilm Adhesion Barrier and Cesarean Delivery
Table 27: Summary of A Prospective Study to Evaluate the Effectiveness of
a Haemostatic Agent in Primary Unilateral THA
Table 28: Summary of the TachoSil Versus SURGICEL Original for the
Secondary Treatment of Local Bleeding in Adult and Pediatric Patients
Undergoing Hepatic Resection Surgery
Table 29: Summary of the Safety and Effectiveness of the Adherus Dural
Sealant System When Used as a Dural Sealant in Cranial Procedures
Table 30: Summary of A Study to Evaluate the Safety and Effectiveness of
EVICEL as an Adjunct to Sutured Dural Repair
Table 31: Summary of Efficacy of Tachosil as Dural Sealant Compared to
Standard Treatment
Table 32: Summary of COVADIS
Table 33: Summary of Effects of CoSeal on Bleeding & Adhesions in
Pediatric Heart Surgery
Table 34: Summary of DREAM
Table 35: Summary of the Neomend ProGEL Pleural Air Leak Sealant
Post-Approval Study
5. SURGICAL HEMOSTAT, INTERNAL TISSUE SEALANT, AND ADHESION BARRIER MARKET
Figure 2: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, Europe (USD), 2010 - 2016
Figure 3: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Country, Europe (USD), 2010 - 2016
Table 36: Factors Impacting the Surgical Hemostat, Internal Tissue
Sealant, and Adhesion Barrier Market, by Product Type, Europe, 2011 - 2016
Table 37: Factors Impacting the Surgical Hemostat, Internal Tissue
Sealant, and Adhesion Barrier Market, by Country, Europe, 2011 - 2016
Table 38: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, Europe (USD and EUR), 2010 - 2016
Table 39: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, Europe (USD), 2010 - 2016
Table 40: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, Europe (EUR), 2010 - 2016
Table 41: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market Growth, by Product Type, Europe, 2011 - 2016
Table 42: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, as a % of Total, Europe, 2010 - 2016
Table 43: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Country, Europe (USD, EUR, and GBP), 2010 - 2016
Table 44: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Country, Europe (USD), 2010 - 2016
Table 45: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Country, Europe (EUR), 2010 - 2016
Table 46: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market Growth, by Country, Europe, 2011 - 2016
Table 47: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Country, as a % of Total, Europe, 2010 - 2016
Table 48: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, France (USD and EUR), 2010 - 2016
Table 49: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, France (USD), 2010 - 2016
Table 50: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, France (EUR), 2010 - 2016
Table 51: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market Growth, by Product Type, France, 2011 - 2016
Table 52: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, as a % of Total, France, 2010 - 2016
Table 53: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, Germany (USD and EUR), 2010 - 2016
Table 54: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, Germany (USD), 2010 - 2016
Table 55: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, Germany (EUR), 2010 - 2016
Table 56: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market Growth, by Product Type, Germany, 2011 - 2016
Table 57: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, as a % of Total, Germany, 2010 - 2016
Table 58: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, Italy (USD and EUR), 2010 - 2016
Table 59: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, Italy (USD), 2010 - 2016
Table 60: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, Italy (EUR), 2010 - 2016
Table 61: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market Growth, by Product Type, Italy, 2011 - 2016
Table 62: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, as a % of Total, Italy, 2010 - 2016
Table 63: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, UK (USD, EUR, and GBP), 2010 - 2016
Table 64: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, UK (USD), 2010 - 2016
Table 65: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, UK (EUR), 2010 - 2016
Table 66: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, UK (GBP), 2010 - 2016
Table 67: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market Growth, by Product Type, UK, 2011 - 2016
Table 68: Surgical Hemostat, Internal Tissue Sealant, and Adhesion Barrier
Market, by Product Type, as a % of Total, UK, 2010 - 2016
Figure 4: Leading Competitors in the Surgical Hemostat, Internal Tissue
Sealant, and Adhesion Barrier Market, as a % of Total, Europe, 2011
Table 69: Leading Competitors in the Surgical Hemostat, Internal Tissue
Sealant, and Adhesion Barrier Market, by Product Type, as a % of Total,
Europe, 2011
Table 70: Leading Competitors in the Surgical Hemostat, Internal Tissue
Sealant, and Adhesion Barrier Market, by Country, as a % of Total, Europe, 2011
Table 71: Leading Competitors in the Surgical Hemostat, Internal Tissue
Sealant, and Adhesion Barrier Market, by Product Type, as a % of Total,
France, 2011
Table 72: Leading Competitors in the Surgical Hemostat, Internal Tissue
Sealant, and Adhesion Barrier Market, by Product Type, as a % of Total,
Germany, 2011
Table 73: Leading Competitors in the Surgical Hemostat, Internal Tissue
Sealant, and Adhesion Barrier Market, by Product Type, as a % of Total, Italy,
2011
Table 74: Leading Competitors in the Surgical Hemostat, Internal Tissue
Sealant, and Adhesion Barrier Market, by Product Type, as a % of Total, UK,
2011
Table 75: Recent Events in the Surgical Hemostat, Internal Tissue Sealant,
and Adhesion Barrier Market, Europe
Table 76: Emerging Products in Development for the Surgical Hemostat,
Internal Tissue Sealant, and Adhesion Barrier Market, Europe, 2011 - 2016
6. SURGICAL HEMOSTAT MARKET
Figure 5: Surgical Hemostat Market, by Country, Europe (USD), 2010 - 2016
Figure 6: Surgical Hemostat Market, by Country, Europe (USD), 2010 - 2016
Table 77: Surgical Hemostat Market, by Country, Europe (USD, EUR, and
GBP), 2010 - 2016
Table 78: Surgical Hemostat Market, by Country, Europe (USD), 2010 - 2016
Table 79: Surgical Hemostat Market, by Country, Europe (EUR), 2010 - 2016
Table 161: Adhesion Barrier Market, by Indication, Italy (USD and EUR),
2011
Table 162: Adhesion Barrier Market, UK (USD, EUR, and GBP), 2010 - 2016
Table 163: Adhesion Barrier Market, by Indication, UK (USD, EUR, and GBP),
2011
Figure 13: Leading Competitors in the Adhesion Barrier Market, as a % of
Total, Europe, 2011
Table 164: Leading Competitors in the Adhesion Barrier Market, by Country,
as a % of Total, Europe, 2011
Figure 14: Leading Competitors in the Nonspine Adhesion Barrier Market, as
a % of Total, Europe, 2011
Table 165: Leading Competitors in the Nonspine Adhesion Barrier Market, by
Country, as a % of Total, Europe, 2011
APPENDIX: METHODOLOGY
APPENDIX: ACRONYMS AND INITIALISMS
Table 166: Acronyms and Initialisms
APPENDIX: BIBLIOGRAPHY
European Markets for Surgical Hemostats, Internal Tissue Sealants, and Adhesion Barriers 2012 published by Millennium Research Group in June 15, 2012. This report price starts from US $ 6195.
