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MicroRNAs and Exosomes Market Report 2012

Abstract

Disease Associations and Circulating Biomarkers

This is the latest and most up-to-date Market Report from Select Biosciences addressing the microRNA and Exosomes markets as they are evolving. In this report, we focus upon the microRNA research marketplace from the perspective of the translational opportunities in these spaces. The focus of this field is moving from basic research towards the utility of associations of microRNA expression patterns in disease. In this manner, microRNA signatures may be validated as biomarkers in many disease areas - cancers, cardiovascular disease, neurological disease, inflammation, and metabolic diseases.

  • Select Biosciences has performed worldwide market tracking wherein we've analyzed end-user research trends in the microRNA as well as Exosome markets - these areas are evolving in parallel given the opportunity in the Circulating Biomarkers space and the utility of microRNAs and mRNAs to be harvested from exosomes and assayed as signatures for disease.
  • For exosomes, we've analyzed the research trends, types of downstream applications being performed as well as biomarker classes being studied currently and this is the First Market Report to Document the Market Landscape of Exosomes.

Select Biosciences has characterized the associations of microRNAs in various disease classes and presents these detailed associations as "hotspot maps" in this report. Specifically, these associations [to be interpreted as starting material for biomarker development and validation] are described for many cancer classes, cardiovascular disease, CNS disease, diabetes, inflammation, and obesity. They offer the opportunity for R&D planning efforts addressing the question of "which microRNA content needs to be addressed in a particular disease class."

This data-driven characterization of the microRNAs and Exosomes landscape is a hands-on document that can be used for competitive benchmarking, business planning, and strategy development - all the data that have been collected in this industry analysis are presented and they form the basis for the conclusions drawn throughout the market report presented in a format enabling "drag-and-drop" into business presentations/business plans - this Market Report is written and delivered to customers in PowerPoint format.

Extensive Technical and Market Analyses Presented in this Report

MicroRNA Research Market Analysis

  • Research Market Size and Growth Rate
  • Grant Funding Metrics
  • Qualitative and Quantitative Research Market Trends
    • Segmentation of Research Activities
    • Market Penetrance of Product Vendors into the microRNA Research Market
    • Unmet Needs

Association of microRNA Expression Patterns in Various Disease Classes

  • Various Types of Cancer: Breast Cancer, Lung Cancer, Prostate Cancer, Pancreatic Cancer, GI Tract Cancers, Hematological Malignancies
  • Muscular Development and Cardiovascular Disease
  • CNS Disease
  • Metabolic Disease, Diabetes
  • Stem Cells
  • Liver Disease, Liver Toxicity

Exosomes Marketplace

  • Nature and Categorization
  • Current Research Trends based on Primary Market Survey
  • Downstream Applications

Circulating Biomarkers

  • Utility of microRNA Signatures
  • microRNA Signatures in Specific Cancers Characterized in Biological Fluids to Date

Table of Contents

Description of Chapters of the Report

Chapter I. MicroRNA Research Market Analysis

  • Scope
  • Segmentation of the RNA Space
  • MicroRNA genes, non-coding RNA genes
  • Primary Market Survey to Assess microRNA Research Trends
    • Qualitative and Quantitative Market Data
  • MicroRNA Grant Funding Metrics in the US
  • miRBase Registry Metrics
  • MicroRNA Research Market Size and Growth Rate
    • Detailed Analysis of microRNA-Focused Publications as a Means to Segment the Space
  • Expansion of the microRNA Field
  • MicroRNA Association Documented in Various Disease Classes : Potential for Development into Biomarkers
  • Translational Value of microRNA Associations
  • The Potential for Long Non-coding RNAs
  • Long Non-coding RNAs Market Trends

Chapter II. MicroRNAs in Physiological and Disease Processes

  • Cancer
  • microRNAs Documented in Chromosomal Alterations/Aberrations
  • Epigenetic Silencing of microRNAs
  • microRNA Expression Profiles in Hematological Malignancies
  • microRNA Expression Profiles in Solid Tumors
  • microRNAs Associated with Outcome in Cancers [Cancer Personalized Medicine]
  • microRNAs in Breast Cancer
  • microRNAs in Lung Cancer
  • microRNAs in Prostate Cancer
  • microRNAs in Pancreatic Cancer
  • microRNAs in GI Tract Cancers
  • Normal Muscle Development and Vascular Disease
    • microRNSs Associated with Vascular Disease, Inflammation and Angiogenesis
    • microRNAs Associated with Cardiac Hypertrophy
  • Diabetes
  • CNS Normal Development and Diseases
  • Stem Cells
  • Hepatic Physiology, Pathology, and Toxicity Screening

Chapter III. Exosomes Market Analysis

  • Exosomes Characteristics
  • Exosomes Market Trends
    • Quantitative Analysis of Research Market Trends
    • Worldwide Market Survey Data and Trends Therein
  • Emerging Space of Circulating Biomarkers
    • Sources of Circulating Nucleic Acids
    • Plasma microRNAs as Candidate Biomarkers in Various Disease Classes
    • Signatures of Circulating Cell-Free microRNAs in Various Cancer Classes
    • Comparison of Various Classes of Biomarkers

Appendix. Research Methodology

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