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2012 France Molecular Diagnostics Market Strategic Analysis: Supplier Shares and Sales Forecasts for 35 Tests/Applications

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This publication has been discontinued on July 23, 2012.

Abstract

This report presents a comprehensive analysis of the French molecular diagnostics market, including:

  • Major issues pertaining to the French molecular diagnostics laboratory practice, as well as key economic, regulatory, demographic, social and technological trends with significant market impact during the next ten years.
  • An extensive review of DNA probe and biochip technologies, test formats, detection methodologies, trends in testing automation and amplification methods.
  • Ten-year test volume and reagent sales forecasts for the following categories:
    • Infectious Diseases
    • Genetic Diseases
    • Cancer
    • Paternity Testing/HLA Typing
    • Forensic Testing
  • Review of testing methodologies an instrumentation technologies.
  • Feature comparison of automated and semiautomated analyzers.
  • Sales and market shares of leading suppliers.
  • Over 60 specific opportunities for molecular diagnostic instruments, test systems, IT and auxiliary products.
  • Profiles of major suppliers, and emerging market entrants, including their sales, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies.
  • Alternative market penetration strategies.
  • Potential market entry barriers and risks.
  • Business planning issues and concerns.

Contains: 850 pages and 36 tables.

Table of Contents

Introduction

Worldwide Market And Technology Overview

  • A. DNA Sequencing
    • 1. Introduction
    • 2. Sequencing Methods
    • 3. Autoradiography
    • 4. The Human Genome Project
    • 5. Sequencing Automation
    • 6. Image Scanners
    • 7. Fluorescent Detection
    • 8. Gene Profiling
    • 9. Gene Expression
    • 10. Polymorphism Screening
    • 11. Protein Interaction Networks
  • B. DNA And RNA Probe Technology
    • 1. Basic Principles
    • 2. Probe Preparation
    • 3. The DNA Probe Test
      • a. Sample Preparation
      • b. Hybridization
      • c. Separation
      • d. Detection/Measurement
    • 4. Test Formats
      • a. Filter Hybridization
      • b. Southern Blot
      • c. Northern Blot
      • d. In Situ Hybridization
      • e. Others
    • 5. Labeling Techniques
    • 6. Amplification Methods
      • Polymerase Chain Reaction
        • Temperature Cyclers
        • PCR Variations
          • Immuno-PCR
          • QC-PCR
          • DAP-PCR
      • Strand Displacement Activation
      • TMA
      • Ligase Chain Reaction
      • Branched DNA
        • Hybridization Protection Assay
      • Nucleic-Acid Sequence-Based Amplification
      • Self-Sustained Sequence Replicase
      • Others
        • Ampliprobe
        • CAR
        • CAS
        • CPT
        • Dendritic Polymer Technology
        • ISO-CR
        • LAT
        • Probe Networks
        • RAMP
        • Repair Chain Reaction
        • Rolling Circles
        • Sequence Independent Gene Amplification
        • Sequence Initiation Reaction
        • SISPA
        • Solid Phase Amplification
  • C. Detection Technologies
    • 1. Radioactive Methods
      • a. Overview
      • b. Major Isotopes
        • P-32
        • S-35
        • H-3
        • I-125
    • 2. Non-Isotopic Methods
      • a. Enzymatic Labels
      • b. Chemical Labeling
        • Indirect Chemical Labeling
        • Direct Chemical Labeling
      • c. Fluorescence
      • d. Chemiluminescence
      • e. Electrical Conductivity
  • D. Instrumentation Review
    • 1. Abbott LCx
    • 2. Beckman Coulter/Biomek FK
    • 3. Becton Dickinson SDA
    • 4. Bio-Rad GeneScope
    • 5. Gen-Probe Tigris
    • 6. Roche Cobas Amplicor
    • 7. Tecan LS Series
  • E. Biochips: Genosensors, Microarrays, and Labs-on-the-Chip
    • Liquid Transportation and Mixing
    • Separation
    • Reaction
    • Detection
  • F. Pharmacogenomics
  • G. Major Applications
    • 1. Microbiology/Infectious Diseases
      • a. Overview
      • b. Major Infectious Diseases
        • AIDS
          • Structure and Composition
          • Classification
          • AIDS Origins
          • Animal Lentivirus Systems
          • Virus Receptors
          • HIV Infections in Humans
            • Pathogenesis and Pathology
          • CD4T Lymphocytes and Memory Cells
          • Monocytes and Macrophages
          • Lymphoid Organs
          • Neural Cells
          • Viral Coinfections
            • Clinical Findings
          • Plasma Viral Load
          • Pediatric AIDS
            • Neurologic Disease
            • Opportunistic Infections
            • Cancer
          • Immunity
            • Virus Isolation
            • Serology
            • Viral Nucleic Acid/Antigen Detection
          • Epidemiology
            • Worldwide Spread of AIDS
            • United States
            • Routes of Transmission
          • DNA Probes
            • Overview
            • Quantitative PCR
            • In Situ PCR
            • Needed Improvements
          • Viral Load/Drug Resistance Testing
          • Genotype and Phenotype Testing
          • Blood Banking Considerations
        • Adenovirus
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
          • Adeno-Associated Viruses (AAV)
        • Anthrax/Bacillus Anthracis
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
        • Babesiosis
          • Background
        • BEA and Other Bartonella Diseases
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
        • Chagas Disease
          • Background
        • Campylobacter
          • Background
          • Diagnostic Tests
        • Culture Identification
          • Vaccines and Drugs
        • Chlamydia
          • Background
            • Chlamydia psittaci
            • Chlmaydia pneumoniae
            • Chlamydia trachomatis
          • Diagnostic Tests
          • Vaccines and Drugs
        • Creutzfeldt-Jakob's Disease
          • Background
          • Blood Transmission
          • Diagnostic Tests
          • Major Commercial and Academic Players
            • Bayer
            • Disease Sciences/Bio Tec Global
            • Imperial College School of Medicine
            • Ortho-Clinical Diagnostics
            • Pall
            • ProMetic Life Sciences
            • Proteome Sciences/Idexx
            • Q-One Biotech
            • Serono
            • U.S. Agricultural Research Service
          • Drugs
          • Vaccines
        • Cytomegalovirus
          • Background
            • Chorioretinitis
            • Gastrointestinal
            • Central Nervous System Disease
          • Diagnostic Tests
          • Vaccines and Drugs
        • Ebola Virus
          • Background
            • Epidemiology
            • Clinical Syndromes
          • Diagnostic Tests
          • Vaccines and Drugs
        • EchoVirus
          • Background
            • Acute Aseptic Meningitisis
            • Encephalitis
            • Exanthems
            • Respiratory Disease
            • Myopericarditis
            • Neonatal Infections
          • Diagnostic Tests
          • Vaccines and Drugs
        • Encephalitis
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
        • Enteroviruses
          • Background
          • Diagnostic Tests
            • Viral Isolation and Identification
            • Antibody Tests
          • Vaccines and Drugs
        • Epstein-Barr Virus
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
        • Gonorrhea
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
        • Hepatitis
          • Hepatitis A
          • Hepatitis B
            • Structure and Composition
            • Replication
          • Hepatitis C
          • Hepatitis D (Delta)
          • Hepatitis E
          • Hepatitis G
          • Hepatitis Infections Pathology
          • Clinical Findings
          • Laboratory Tests
            • Hepatitis A
            • Hepatitis B
            • Hepatitis C
            • Hepatitis D
            • Hepatitis E
          • Virus-Host Immune Reactions
          • Epidemiology
            • Hepatitis A
            • Hepatitis B
            • Hepatitis C
            • Hepatitis D (Delta)
          • Vaccines and Drugs
        • Herpes Simplex Virus
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
        • Legionella
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
        • Lyme Disease
          • Background
            • Clinical Description
            • Clinical Case Definition
            • Laboratory Criteria for Diagnosis
            • Case Classification
          • Diagnostic Tests
          • Vaccines and Drugs
        • Malaria
        • Mycoplasma
          • Background
            • Ureaplasma Urealyticum & Mycoplasma Hominis
          • Diagnostic Tests
          • Vaccines and Drugs
        • Papillomaviruses/HPV
          • Background
            • HPV in Cancer
            • Cervical Neoplasm
          • Diagnostic Tests
          • Vaccines and Drugs
            • Prevention
        • Parvovirus B19
          • Background
            • Microbiology
            • Epidemiology
            • Clinical Syndromes
            • Erythema Infectiosum (Slapped Cheek)
            • Adult Polyarthropathy
            • Transient Aplastic Crisis
            • Transient Pancytopenia
            • Red Cell Aplasia in Immunocompromised
            • Perinatal Infections
          • Diagnostic Test
          • Vaccines and Drugs
        • Pneumonia
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
        • Polyomaviruses
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
        • Salmonellosis
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
        • Shigellosis
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
        • Streptococci
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
            • Group A Streptococci
            • Group B Streptococci
        • Toxoplasmosis
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
        • Tuberculosis
          • Background
          • Diagnostic Tests
            • Microscopic Characteristics
            • Cultural Characteristics
            • Skin Tests
            • MDRTB
          • Vaccines and Drugs
        • West Nile Virus
          • Background
            • Clinical Syndromes
          • Diagnostic Tests
          • Vaccines and Drugs
        • Yersinia
          • Background
          • Diagnostic Tests
          • Vaccines and Drugs
      • c. Antibiotic Susceptibility
    • 2. Cancer Testing
      • a. Overview
      • b. Major Cancer Types
        • Prostate
        • Lung
        • Colon and Rectum
        • Breast
        • Skin
        • Uterine
        • Leukemia
        • Oral
      • c. Oncogenes
        • Abl/abl-bcr
        • AIB1
        • BCL-2
        • BRCA1
        • CD44
        • C-fos
        • C-myb
        • C-myc
        • CYP17
        • Erb-B
        • HPC1
        • N-myc
        • P40
        • P51
        • P53
        • PIK3CA
        • PTI-1
        • Ras
        • Reg
        • Sis
        • Src
    • 3. Genetic Diseases
      • a. Overview
      • b. Nucleic Acid Amplification
      • c. Chromosome Imaging
      • d. Genomics Technologies
      • e. Proteomics Technologies
      • f. Current Pharmacogenomic Tests
      • g. Future Pharmacogenomic Testing
      • h. Major Diseases
        • Achondroplasia
        • Autosomal Dominant Polycystic Kidney Disease
        • Cancer
        • Cosmetogenomics
        • Cystic Fibrosis
        • Down's Syndrome
        • Duchenne and Becker Muscular Dystrophy
        • Factor V (Leiden)
        • Factor IX Deficiency
        • Fragile X Syndrome
        • Heart Disease
        • Hemochomatosis
        • Hemophilia
        • Huntington's Disease
        • Maternal-Fetal Incompatibility
        • Multiple Endocrine Neoplasia
        • Phenylketonuria (PKU)
        • Polycystic Kidney Disease (PKD)
        • Prenatal Screening
        • Retinitis Pigmentosa
        • Retinoblastoma
        • Sickle Cell Anemia
        • Spinal Muscular Atrophy
        • Vitamin B12 Metabolism
      • i. Social Issues and Concerns
    • 4. Forensic Testing
      • a. Overview
      • b. Multilocus and Single Locus Probes
        • Multilocus Probes
        • Single Locus Probes
        • PCR and RFLP
      • c. The FBI
      • d. DNA Profile Data Banks
        • U.S.A.
        • U.K.
      • e. Judicial Implementation
      • f. Major Crime Categories
      • g. Factors Contributing to the DNA Probe Market Expansion
        • Technology Availability
        • Use of Hair as Evidence
      • h. Wildlife Forensics
    • 5. Paternity Testing/HLA Typing
    • 6. Other Applications
      • a. Disease Susceptibility Testing
      • b. Cardiovascular Diseases
      • c. Diabetes
      • d. Alzheimer's Disease
      • e. Periodontal Disease
      • f. Plasma Purification
      • g. Organ Transplantation
      • h. Water Contamination
      • i. Other
  • H. Competing/complementing Technologies
    • 1. Monoclonal Antibodies/Immunoassays
    • 2. RNA Probes
    • 3. Two-Dimensional Electrophoresis
    • 4. Flow Cytometry

France

  • A. Executive Summary
  • B. Business Environment
  • C. Market Structure
  • D. Market Size, Growth And Major Suppliers' Sales And Market Shares

Major Product Development Opportunities

  • A. Instrumentation
  • B. Reagent Kits and Test Systems/panels
  • C. Computers, Software and Automation
  • D. Auxiliary Products

Design Criteria For Decentralized Testing Products

Alternative Market Penetration Strategies

  • A. Internal Development
  • B. Collaborative Arrangements
  • C. University Contracts
  • D. Distribution Strategies For Decentralized Testing Markets
    • 1. Marketing Approaches
    • 2. Product Complexity
    • 3. Customer Preference
    • 4. Established Suppliers
    • 5. Emerging Suppliers
    • 6. Major Types Of Distributors
    • 7. Market Segmentation

Potential Market Entry Barriers And Risks

  • A. Market Maturity
  • B. Cost Containment
  • C. Competition
  • D. Technological Edge And Limitations
  • E. Patent Protection
  • F. Regulatory Constraints
  • G. Decentralized Testing Market Challenges

Competitive Profiles

  • Abbott
  • Affymetrix
  • Agilent
  • Applied Gene Technologies
  • Arca
  • Beckman Coulter/Danaher
  • Becton Dickinson
  • Biokit
  • BioMerieux
  • Bio-Rad
  • Biotest
  • Caliper
  • Cepheid
  • Decode
  • Diadexus
  • Eiken
  • Enzo
  • Exact Sciences
  • Fujirebio
  • Gen-Probe
  • Hologic
  • Illumina
  • Innogenetics/Solvay
  • Kreatech
  • Li-Cor Biosciences
  • Life Technologies
  • Monogram Biosciences
  • Myriad Genetics
  • Nanogen/Elitech
  • Novartis
  • Orchid CellMark
  • Ortho-Clinical Diagnostics
  • Proteome Sciences
  • Qiagen
  • Roche
  • Scienion
  • Sequenom
  • Shimadzu
  • Siemens
  • Sierra Molecular
  • Takara Bio
  • Tecan Group

Appendixes

  • Appendix I: Major Universities and Research Centers Developing Molecular Diagnostic Technology
  • Appendix II: Glossary of Terms
  • Appendix III: Currency Exchange Rates

List of Tables

  • Major Companies Developing or Marketing AIDS Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Adenovirus Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Campylobacter Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Chlamydia Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing CMV Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing EBV Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Gonorrhea Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Hepatitis Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Herpes Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Legionella Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Lyme Disease Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Mycoplasma Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Papilloma Virus Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Pneumonia Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Salmonella Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Shigella Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Streptococci Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Toxoplasmosis Molecular Diagnostic And Other Direct Identification Tests
  • Major Companies Developing or Marketing Tuberculosis Molecular Diagnostic And Other Direct Identification Tests
  • Oncogenes Potential Application in Cancer Diagnosis
  • Major Companies Developing or Marketing Cancer Molecular Diagnostic Tests
  • Major Companies Developing or Marketing Molecular Diagnostic Test For Genetic Diseases
  • Summary Table France, Molecular Diagnostic Test Volume And Sales Forecast by Major Application
  • France, Laboratories Performing DNA Sequencing By Market Segment
  • France, Molecular Diagnostics Market Potential Laboratory Universe by Market Segment
  • France, Molecular Diagnostic Test Volume Forecast By Major Application
  • France, Major Infectious Disease Molecular Diagnostics Test Volume Forecast
  • France, Infectious Disease Screening NAT Volume Forecast
  • France, Molecular Diagnostics Market Forecast By Major Application
  • France, Infectious Disease Screening NAT Reagent Market Forecast by Test
  • France, Molecular Diagnostics Market By Major Supplier
  • France, HIV/Hepatitis NAT Market Reagent Sales By Major Supplier
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