PUBLISHER: Allied Market Research | PRODUCT CODE: 1193239
PUBLISHER: Allied Market Research | PRODUCT CODE: 1193239
The global high potency APIs market was valued at $19,693.65 million in 2021, and is projected to reach $41,373.34 million by 2031, registering a CAGR of 7.7% from 2022 to 2031.
High potency APIs are the substances that elicit a biological response even at very low doses. Cytotoxic substances and sex hormones like oestrogen are the common examples of HPAPIs which are highly selective in nature and show response at low doses. Moreover, the API development sector including the development of the HPAPIs, is the fastest expanding area of the pharmaceutical industry due to the development of the highly potent drugs such as fentanyl, alprazolam, risperidone, bumetanide, bisoprolol that evokes response at low concentrations and are into the market for the treatment of various ailments. In addition, more than 1,000 highly potent small molecules are under development that have their applications in the treatment of diseases like cancer, diabetes, glaucoma, and others.
According to the National Glaucoma Research, more than three million Americans have glaucoma, and 2.7 million of these patients are aged 40 and older and are affected by its most common form, open-angle glaucoma. Also, in 2020, about 80 million people have glaucoma globally, and this number is expected to increase to over 111 million by 2040. This rise in the number of the glaucoma patients, along with the prevalence of other multi-genetic disorders such as cancer, diabetes, and others around the globe, propel the growth of the high potency APIs market.
Furthermore, the key market players in the market are focusing on the emerging economies such as India, China and the Middle East Asia for investment and expansion of their business. The rise in the population in this region, along with prevalence of the excessive raw materials for the manufacturing and funding offered by the government are the factors driving the growth of the market in this region. In addition, NCBI states that the primary angle closure glaucoma (PACG) is higher in Asians than Europeans and Africans, with over 80% of the total cases globally, which highlights the investment opportunities for the key market players in the high potency APIs market during the forecast period.
In addition, there is an increase in the demand for oncology drugs due to the prevalence of the cancer cases around the globe. Also, advancements in HPAPI manufacturing technologies along with the rise in the number of contract manufacturing organization (CMOs) and contract development and manufacturing organization (CDMOs) are the factors driving the growth of the market. On the other hand, the patent expiry and launch of the generic versions of the highly potent APIs are projected to provide lucrative opportunity for the pharmaceutical companies to enhance product portfolio and expand their business.
However, the market is expected to be significantly constrained in the near future due to the high risk of cross-contamination and high development cost associated with the manufacturing process. The market is capital intensive and requires skilled technical human capital. This is projected to be a major barrier for new entrants entering the market.
The high potency APIs market is segmented on the basis of product type, application, type of synthesis and region. By product type, it is divided into innovative high-potency API and generic high-potency API. On the basis of application, the market is segmented into oncology, hormonal imbalance, glaucoma, and others. According to the type of synthesis, the market is segmented into synthetic and biotech. The biotech is further divided into merchant and captive. Region wise, it is analyzed across North America, Europe, Asia-Pacific, and LAMEA.
The major companies profiled in this report include Abbvie Inc., Bayer AG, Boehringer Ingelheim International GmbH, Bristol-Myers Squibb, Eli Lilly and Company, F. Hoffmann-La Roche Ltd, Novartis AG, Pfizer Inc., Sanofi, Teva Pharmaceutical Industries Ltd. and others.
Key Benefits For Stakeholders
By Application
By Type of Synthesis
By Product Type
By Region