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Market Research Report
Product code
937208
Preimplantation Genetic Testing Market, By PGD/PGS, By Type, By Application and By Geography - Analysis, Share, Trends, Size, & Forecast From 2020 - 2026 |
Preimplantation Genetic Testing Market, By PGD/PGS, By Type, By Application and By Geography - Analysis, Share, Trends, Size, & Forecast From 2020 - 2026 |
Published: May 1, 2020
AnalystView Market Insights
Content info: 233 Pages
Delivery time: 2-3 business days
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Preimplantation genetic testing market was valued at USD 175.3 million by 2019, growing with 9.2% CAGR during the forecast period, 2020-2026
Market Dynamics
Abnormality in the chromosomal number is the prime cause of failure in the pregnancy concieved in natural or by invitro fertilization. Espeically in case of IVF, different technologies have introduced to identify that equal number of chromosomes are present in each of the haploid chromosomal set. Preimplantation genetic testing (PGT) also known as embryo biopsy is the test performed on the embryo for analzing the genetic abnormalities prior to its incorporation into the womb in the process of in-vitro fertilization (IVF). It is used for identification of any possible genetic defect in these embryos in IVF. It is early type of prenatal genetic diagnosis used for investigating prenatal screening of the emobryo prior to implantation. PGT is performed for ensuring that the embryo introduced shows high prevalence of healthy and normal pregnancy. PGT has emegered as an useful test for the couples with genetic disorders, which have high probablity of transferring into the baby as well.
PGT involves testing of monogentic diseases, structural aggrangement of the chromosome and abnormal chromosomal number. The growth of the PGT market is experiencing growth owing to rise in success rate in the in-vitro fertilzation. Increasing adoption of IVF technique due to rising issues regarding infertility within both genders, an outcome of unhealthy lifestyle. Ongoing advancement in the area of IVF, to increase chance of healthy pregnancy, is driving the worldwide industry growth. Also, rise in genetic disorders is another factor fueling the demand for IVF. According to the World Health Organization (WHO), the prevalence of all single-gene disorders at birth is 10 in 1,000. Aforementioned factors would, in turn, support the market growth to great extent. On the flip side, high cost associated with this procedure is expected to pull back the market growth in future. In addition to this, ethical concerns with PGT is another factor hindering the market growth.
PGD/PGS Takeaway
Among PGD and PGS, PGD accounted for more than 50% of the total market share in 2019. Preimplantation genetic diagnosis (PGD) includes testing of the embryo having either of the parents with some kind of genetic abnormilities. Rise in genetic disorders with higher awareness regarding inheritance of the genetic disorders is driving the demnad for PGD testing. Also, higher efficiency of PGD to detect the genetic disorders in the embryo is also promoting its adoption. Also, different studies has revealed that PGD possess ability to diagose over 2,000 inherited single gene disorders with accuracy of around 98% in identifying affected and unaffected embryos.
Type Takeaway
Basis on types, the market is divided into chromosomal abnormalities, HLA Typing, embryo testing, X-linked diseases, and aneuploidy screening. In 2019, the chromosomal abnormalities gained highest market share. Increasing use of PGT for eliminating the risk associated with miscarriage and improve success of IVF. High incidence of chromosomal incidence in the IVF embryos lowering the success chances of the IVF. Various studies revealed that over 50% of the preimplantation embryos have abnormal chromosomal number including polyploidy or aneuploid. This, drives the demand for preimplantation genetic testing market.
Application Takeaway
Application segment is further classified into the IVF prognosis, embryo HLA typing, late onset genetic disorders, and inherited genetic disease. Out of these, in 2019, the embryo HLA typing category gained the leading position valued at USD 55.9 million. It is important in preventing tranferring of the genetic diseases. The adoption of the PGT with HLA typing is increasing at a significant pace owing to increase in awareness among the couples as a radical treatment. HLA typing has emerged as new method of treatment with higher preference especially fot the diseases requiring stem cell transplantation for potential treatment.
Regional Takeaway
On the basis of region, the North America and Europe accounted for significant poisition in the preimplantation genetic testing market. In North America, the rise in infertility issues especially among the couples suffering from genetic disorders is driving the demand for PGT, for sucessful pregnancy. As per American Society for Reproductive Medicine, 15% of the couples are infected the fertility wherein around 15%-30% of male factor infertility is owing to genetic abnormalities. Increasing patient pool with higher adoption of the PGT in the Europe is boosting the regional market growth.
Key Vendor Takeaway
F. Hoffmann-La Roche Ltd., Genea Limited, Illumina, Inc., Quest Diagnostics Incorporated., Natera Inc., CooperSurgical, Inc., Laboratory Corporation of America Holdings, Thermo Fisher Scientific, Inc., Igenomix, Bioarray S.L., Oxford Gene Technology, Invitae Corporation, PerkinElmer Inc., Reproductive Genetic Innovations, LLC. and California Pacific Medical Center (CPMC) are the key players operating in the preimplantation genetic testing market.
Increasing clinical studies directing towards second-generation preimplantation with unfavorable reproductive and IVF prognosis for improved outcome. Companies are entering into partnership and new product launches for preimplantation genetic testing. For instance, in 2019, Illumina partnered with the Vitrolife for distribution of pre-implantation genetic testing kit. This kit was specifically designed for monogenic and single gene defects (HumanKaryomap-12) and aneuploidy (PGT-A) (VeriSeq PGS). Likewise, in October 2019, PerkinElmer launched PG-Seq Rapid Non-Invasive Preimplantation Genetic Testing for Aneuploidy (PGT-A) kit.
The market size and forecast for each segment and sub-segments has been considered as below:
Historical Year - 2015 to 2018
Base Year - 2019
Estimated Year - 2020
Projected Year - 2026
TARGET AUDIENCE
Traders, Distributors, and Suppliers
Manufacturers
Government and Regional Agencies
Research Organizations
Consultants
Distributors
SCOPE OF THE REPORT
The scope of this report covers the market by its major segments, which include as follows:
GLOBAL PREIMPLANTATION GENETIC TESTING MARKET KEY PLAYERS
Thermo Fisher Scientific, Inc.
Igenomix
Bioarray S.L.
Quest Diagnostics Incorporated.
Natera Inc.
Oxford Gene Technology
Invitae Corporation
PerkinElmer Inc.
Reproductive Genetic Innovations, LLC
California Pacific Medical Center (CPMC)
F. Hoffmann-La Roche Ltd.
Genea Limited
Illumina, Inc.
CooperSurgical, Inc.
Laboratory Corporation of America Holdings
GLOBAL PREIMPLANTATION GENETIC TESTING MARKET BY PGD/PGS
Preimplantation Genetic Screening (PGS)
Preimplantation Genetic Diagnosis (PGD)
GLOBAL PREIMPLANTATION GENETIC TESTING MARKET, BY TYPE
Aneuploidy Screening
Chromosomal Abnormalities
HLA Typing
X-linked Diseases
Embryo Testing
Fresh Embryo (Donor Eggs)
Fresh Embryo (Own Eggs)
Frozen Embryo (Donor Eggs)
Frozen Embryo (Own Eggs)
Other PGT Types
GLOBAL PREIMPLANTATION GENETIC TESTING MARKET, BY APPLICATION
Late Onset Genetic Disorders
Inherited Genetic Disease
Embryo HLA typing for stem cell therapy
IVF Prognosis
Others
GLOBAL PREIMPLANTATION GENETIC TESTING MARKET, BY REGION
North America
The U.S.
Canada
Europe
Germany
France
Italy
Spain
United Kingdom
Rest of Europe
Asia Pacific
India
China
South Korea
Japan
Singapore
Rest of APAC
Latin America
Brazil
Mexico
Argentina
Rest of LATAM
Middle East and Africa
Saudi Arabia
United Arab Emirates
Rest of MEA
TABLE Middle East and Africa Preimplantation genetic testing market, by Type, 2015-2026 (USD Million)
TABLE Middle East and Africa Preimplantation genetic testing market, by Type, 2015-2026 (USD Million)