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PUBLISHER: Arizton Advisory & Intelligence | PRODUCT CODE: 1181648

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PUBLISHER: Arizton Advisory & Intelligence | PRODUCT CODE: 1181648

Biosimilar Contract Manufacturing Market - Global Outlook & Forecast 2022-2027

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The global biosimilar contract manufacturing market is expected to grow at a CAGR of 16.19% during 2022-2027.

MARKET OUTLOOK

  • More than 2 billion people worldwide cannot afford life-saving medicines, putting their lives at risk. Producing potentially life-saving drugs that are more accessible and affordable can help today's patients live better lives for a prolonged period and minimize health inequality. Biologic drugs are at the forefront of therapeutic developments, but their high cost accounts for a significant portion of public and private drug expenditure. Comparatively, biosimilars are an equivalent effective drug at an affordable price, offering the promise of a more sustainable solution. As a result, the biosimilar market continues to post massive growth across all regions worldwide. Since 2015, the biosimilars market has been growing at a CAGR of more than 50%, and the future looks even better, with several favorable factors supporting its high growth. The increasing acceptance of biosimilars in treating diseases, such as autoimmune diseases, cancer, and blood disorders, coupled with the low cost of biosimilars compared to branded biologics, are some of the major factors driving the market.
  • With the increasing demand for biosimilars, rise in approved biosimilars, and robust pipeline, the demand for outsourcing biosimilars manufacturing is also equally increasing. As a result, many pharma and biotech companies outsource biosimilar R&D and manufacturing to CMOs & CDMOs, which propel the biosimilar contract manufacturing market growth. Outsourcing biosimilar manufacturing enables pharma/biotech companies to reach the market early, free up their resources and manufacturing facilities, focus more on their core businesses and minimize the costs of their drugs. As a result, the CMOs industry is witnessing remarkable growth during the last decade and is expected to continue an even better growth trajectory in the coming years. The CMOs industry is undergoing a paradigm shift. Off-late CMOs are no longer working as just a one-off manufacturing option but have become an integral part of the supply chain of pharma/biotech companies.
  • In the beginning, major pharma companies continue to be significant contributors to the growth of the biopharma contract manufacturing market; contributions from biotechnology & life sciences companies also increasing in recent years, especially when the demand for biologics, including biosimilars, is at an all-time high worldwide. With the market entry of many biotech companies, there will be greater demand for contract manufacturing services in biologics, including the biosimilars market. Outsourcing the manufacturing function will enable biotech firms to introduce their products in the market without investing in building or upgrading their manufacturing units. As the costs of biosimilars must be kept significantly low, it makes sense for drug developers to outsource manufacturing activities to keep costs low. As a result, CMOs are witnessing healthy growth in their business from the biosimilar contract manufacturing market.
  • The demand for contract manufacturing services is gaining momentum owing to the increase in investments by big pharma companies for the R&D of various biologics and biosimilars. Moreover, the significant advantage of the reduction in overall investment for developing and manufacturing drugs with contract manufacturing is expected to increase the adoption of contract manufacturing services by pharma/biotech companies in the coming years. Leading CMOs are expanding their existing manufacturing capacities to maintain their strong position in the biosimilar contract manufacturing market. For instance, in April 2018, Catalent Pharma Solutions completed a USD 5.5 million expansion program at its 200,000+ square foot Philadelphia, Pennsylvania manufacturing site to provide additional clinical packaging and storage capacity.

MARKET TRENDS & OPPORTUNITIES

The Rise in Product Launches & Approvals of Biosimilars

  • The growing number of recent launches in biosimilars are demonstrating a wide range of uptake depending on the molecule and the geography. North America and Europe have accounted for the highest volume of global biosimilar volume; however, greater volume growth rates are expected in the major Asian markets, Southeast Asia, Latin America, and Australasia, in the next decade.
  • The first biosimilar approved by the US FDA was Sandoz's Zarxio in 2015. Later in 2020, there was a decrease in the annual number of biosimilars approved in the US. In 2019, FDA approved a record-breaking ten biosimilars. But in 2020, FDA only approved three new biosimilars. Additionally, few biosimilars entered the market in 2020, with five being launched compared to seven in 2019. By 2022, the FDA approved 33 biosimilars, of which 21 are available on the US market. In China, a significant surge in the approvals of biosimilars was witnessed from 2018 to 2021, with 13 new biosimilars being approved. The latest regulation changes and biosimilar pipeline will likely drive the biosimilar industry. The demand for biosimilars will constantly be growing due to the rising number of inflammatory and autoimmune diseases. This has been further favored by the patent expirations of the blockbuster biologic drugs, which are highly expensive compared to the highly cost-effective biosimilars. This will further increase the demand for outsourcing the manufacture of biosimilars and contribute to the biosimilar contract manufacturing market's growth.

Patent Expirations of Blockbuster Branded Biologic Drugs

  • The first 17 blockbuster drugs with annual peak sales reaching USD 60 billion will likely lose exclusivity between 2020 and 2025, creating a market entry of many novel biosimilars. The uptake of biosimilars is rising in many specialties and across channels where biosimilars have been introduced more recently. Biologics has been a rapidly evolving area within the biotechnology sector. The treatment of cancers, diabetes, and autoimmune diseases account for more than 60% of the biologics market, making it highly expensive and increasing daily. As per the World Health Organization (WHO), such prices limit healthcare systems from providing affordable and population-wide access to such medicines.
  • One way to combat the limitations for the use of biologicals and the subsequent pressure on healthcare budgets is to introduce biosimilars where the patents and exclusivity periods of the originator biologicals have expired. By 2018, biologicals worth more than USD 68 billion in annual sales lost patent protection. A 20% discount could save USD 14 billion, while a 30% or 40% discount could save USD 20 billion or USD 27 billion, respectively. By 2025 several biologic patents will have expired in many countries, which could translate into an opportunity to develop new biosimilars. Europe can be seen as a key region with more opportunities to be explored in the biosimilar contract manufacturing market.

Robust Pipeline of Biosimilars Boosting Contract Manufacturing

  • The global biopharmaceutical industry is being expanded by many new products, players, and production facilities thanks to biosimilars. With this, the number of approved and investigational biosimilars is increasing. The competition among biosimilars (including their reference products) will thus rise dramatically in the upcoming years. This includes several developers focusing on biosimilars of many of the same reference products.
  • Biosimilars have recently been introduced in new therapeutic segments, with reimbursement models continuing to evolve. The biosimilar pipeline is rapidly progressing and growing, with more products and companies getting involved in the manufacturing process. Biosimilars observed sustained growth in 2019, with an average growth of 20% per year. This growth is increasing at an average of 27% per year in the last five and half years.
  • With several commercially-viable biosimilars lacking product protection and approaching patent expiry, there are currently multiple biosimilars in the pipeline. The number of biosimilars in the pipeline, of which most are still in development, targeting the same popular reference products, has risen in the past 18 months with an average of over 50% yearly. This high growth rate in the pipeline of biosimilars is reflected in the growth of biosimilar numbers targeting other less popular reference product targets. This growth in the number of biosimilars in the development targeting the same reference products will likely continue in the short term in coming years, as more current biosimilar companies are extending their portfolios of products in development and new developers continue to enter the field.

MARKET SEGMENTATION

INSIGHTS BY SOURCE

Biosimilars are developed and manufactured using mammalian and non-mammalian cell lines. The mammalian cell lines segment dominated the global biosimilar contract manufacturing market with a share of around 71% and is also the fast-growing segment. The production of biosimilars, generation of manufacturing cell lines, and optimization of manufacturing scale-up require tight control conditions and detailed analytics to ensure the biosimilar composition profile fits within the specifications of originators. For the generation of proteins for discovery research and biotherapeutic application, mammalian cell recombinant expression can help produce proteins that correctly mimic properties in a human patient.

The global non-mammalian biosimilar contract manufacturing market is growing at a CAGR of 15.54%. Non-mammalian products include biotherapeutics developed for microbial sources. The source of microbial systems is commonly used for generating recombinant protein therapeutics. Around 650 protein drugs have been approved globally, with about 400 derived from recombinant microbial technologies.

Segmentation by Source:

  • Mammalian
  • Non-mammalian

INSIGHTS BY SCALE OF OPERATION

Based on the scale of operation, the global biosimilar contract manufacturing market is segmented into commercial and research segments. In 2021, commercial accounted for the share of 85.73% in the global biosimilar contract manufacturing market. With the emergence of various chronic inflammatory conditions, cancers, autoimmune diseases, and others, there has been a growing demand for developing novel biosimilars.

Several biosimilars are in the pipeline. Due to the short span and urgency of biosimilars, researchers are working to ensure that the biosimilar can be reliably replicated at a scale for clinical trials and then again at an even greater scale for mass production. Contract manufacturing is witnessing a growing uptake because biosimilar drugs are approaching the commercial scale and entering the clinical pipeline. Even though they have well-established GMP-grade facilities, larger biopharma companies prefer to outsource manufacturing to cut costs. Contract manufacturers utilize cell-culture and microbial technologies to provide manufacturing services on a clinical and commercial scale. As a result, the contract manufacturing of biosimilars for various research activities is increasing and contributing to the growth of the research segment.

Segmentation by Scale of Operation:

  • Commercial
  • Research

INSIGHTS BY PRODUCT

Contract manufacturing activities can be broadly divided into APIs manufacturing and FDF manufacturing. In 2021, the finished dosage form (FDF) accounted for 52.88% of the global biosimilar contract manufacturing market. An FDF is a drug product that has undergone all the production steps, including manufacturing, testing, and approval, before being delivered to the public. The FDF is an essential stage in the product life cycle, and it can only be accomplished if the pharmaceutical company's or outsourced manufacturing organization's manufacturing facilities meet high standards. Companies that do not have a standard manufacturing facility for the production of FDFs license for this primary reason.

APIs contract manufacturing shows the development of drugs with the help of contract manufacturing by outsourcing other companies. The global APIs contract manufacturing market is expected to witness increased demand during the forecast period as it has access to a skilled workforce with economical costs, favorable government policies, and tax incentives. The global active pharmaceutical ingredient biosimilar contract manufacturing market was valued at USD 1.065 billion in 2021. Manufacturing APIs is a complex and specialized activity that requires integration by chemistry, biology, and engineering experts.

Segmentation by Product:

  • Finished Dosage Form (FDF
  • Active Pharmaceutical Ingredients (APIs)

INSIGHTS BY INDICATION

The global biosimilar contract manufacturing market is segmented into oncology, blood disorders, inflammation & autoimmune disorders, and other indications under the indication segment. Among these, the oncology segment dominates the industry and accounts for a 33.5% share. The development of biosimilars has been closely linked between therapeutic areas, prevalence, and the cost of diseases. Immunology and oncology are therapeutic areas with a financial burden on the healthcare systems; therefore, biosimilars are highly needed. Most FDA & EMA-approved biosimilars target inflammatory conditions. This is majorly due to the growing disease and cost burden of these chronic diseases, which is boosting the development of biosimilars, as these are highly productive and available at low costs.

Segmentation by Indication:

  • Oncology
  • Blood Disorders
  • Inflammatory & Autoimmune Disorders
  • Others

GEOGRAPHICAL INSIGHTS

Europe dominates the global biosimilar contract manufacturing market, with the most significant share of 39.44% in 2021, and is expected to grow at a CAGR of 15.14% during the projected period. A well-defined regulatory framework for biosimilars and an established biosimilar industry with leading companies such as Lonza, Boehringer Ingelheim GmbH, Rentschler Biopharma SE, and others have contributed to the increasing demand for contract manufacturing of biosimilars. Germany, France, the UK, Italy, and Spain are the major countries contributing to the region's biosimilar contract manufacturing market growth.

North America accounted for the second-highest share in the global biosimilar contract manufacturing market. Significant factors contributing to its constant growth in the market include the rising popularity of treating major chronic conditions such as inflammatory and autoimmune diseases that comprise cancers, blood disorders, and others; favorable regulatory policies and guidelines. The North American biosimilar contract manufacturing market was valued at USD 626.41 million in 2021. The development of biosimilars in the region is strictly regulated. Only those presenting a totality-of-evidence dossier with highly similar physicochemical, biological, and clinical performances are endorsed by regulatory agencies as biosimilars.

APAC will likely witness the fastest growth in the global biosimilar contract manufacturing market during the forecast period. The growing patient population with major inflammatory diseases and autoimmune disorders is raising the need for biosimilars in the region. This region has the significant advantage of less expensive treatment due to the massive income of many medical travelers. Also, rapid urbanization, growing R&D expenditures, and rising biosimilar manufacturing outsourcing will contribute to its continuous market growth. In 2021, Latin America and Middle East & Africa accounted for minimal shares in the biosimilar contract manufacturing market. These regions are expected to witness slow growth in the coming years with the emergence of biosimilar manufacturers outsourcing their products to contract manufacturers. In addition, regulations are being adjusted to facilitate the manufacture and registration of biosimilars that will significantly expand in these markets.

Segmentation by Geography

  • APAC
    • China
    • India
    • Japan
    • South Korea
    • Australia
  • North America
    • US
    • Canada
  • Europe
    • Germany
    • Spain
    • France
    • Italy
    • UK
  • Latin America
    • Brazil
    • Mexico
    • Argentina
  • Middle East & Africa
    • South Africa
    • South Arabia
    • UAE
    • Turkey

VENDOR LANDSCAPE

The global biosimilar contract manufacturing market is concentrated with key players such as Samsung biologics, Lonza, and Boehringer Ingelheim GmbH. Emerging players include AbbVie, Inc., Catalent, Emergent BioSolutions, FUJIFILM Diosynth Biotechnologies, Merck KGaA, Pfizer CentreOne, and WuXi Biologics. Most leading players focus on acquisitions, partnerships, diversifying their outsourcing services, and strengthening their distribution networks to increase their industry share. They are majorly involved in expanding existing and new markets to serve the needs of growing customer bases and boost their production capabilities to gain end-user traction.

The emergence of several emerging players intensified the competition among vendors. Major vendors offering biosimilar contract manufacturing services are present in Europe's region, including small, mid-sized, or large companies. North America and APAC contain fewer larger players and several small and mid-sized vendors. Emerging economies that include China, India, Brazil, and Mexico will likely offer significant growth opportunities for players in the biosimilar contract manufacturing market. Major vendors are becoming more active and concentrating on more diverse contract manufacturing services as required by end-users in light of growing competition and the emergence of multiple businesses.

Key Vendors

  • Lonza
  • Boehringer Ingelheim International GmbH
  • Catalent
  • FUJIFILM
  • Thermo Fischer Scientific

Other Prominent Vendors

  • AbbVie
  • Abzena
  • AGC Biologic
  • Alcami
  • Almac Group
  • Avid Bioservices
  • Biocon
  • Element Materials Technology
  • Eurofins Scientific
  • Fresenius Kabi
  • Goodwin Biotechnology
  • Kemwell
  • mAbxience
  • Merck KGaA
  • Midas Pharma
  • Novartis AG
  • Pfizer
  • Rentschler Biopharma
  • Samsung Biologics
  • WuXi Biologics

Recent developments In The Global Biosimilar Contract Manufacturing Market

  • Celltrion and Lonza announced a contract manufacturing agreement to produce a drug substance for Remsima, a biosimilar approved by the EMA and the FDA for several autoimmune diseases, including Crohn's disease and rheumatoid arthritis.
  • Novartis made a contract manufacturing deal with Carisma Therapeutics, a firm developing a cell therapy platform that has developed CT-0508 for targeting HER2- positive solid tumors.
  • Lonza, a leading global Biopharmaceuticals CDMO, and Junshi Biosciences collaborated to accelerate the development and manufacturing of biologics using Lonza's GS Xceed Gene Expression System in April 2021.

KEY QUESTIONS ANSWERED

  • 1. What is the projected biosimilar contract manufacturing market by 2027?
  • 2. What is the growth rate of the global biosimilar contract manufacturing market?
  • 3. Who are the key players in the global biosimilar contract manufacturing market?
  • 4. What are the key driving factors in the biosimilar contract manufacturing market?
  • 5. Which region dominates the global biosimilar contract manufacturing market?
Product Code: ARZ221113

TABLE OF CONTENTS

1 RESEARCH METHODOLOGY

2 RESEARCH OBJECTIVES

3 RESEARCH PROCESS

4 SCOPE & COVERAGE

  • 4.1 MARKET DEFINITION
    • 4.1.1 INCLUSIONS
    • 4.1.2 EXCLUSIONS
    • 4.1.3 MARKET ESTIMATION CAVEATS
  • 4.2 BASE YEAR
  • 4.3 SCOPE OF THE STUDY
    • 4.3.1 MARKET SEGMENTATION BY SOURCE
    • 4.3.2 MARKET SEGMENTATION BY SCALE OF OPERATION
    • 4.3.3 MARKET SEGMENTATION BY PRODUCT
    • 4.3.4 MARKET SEGMENTATION BY INDICATION
    • 4.3.5 MARKET SEGMENTATION BY GEOGRAPHY

5 REPORT ASSUMPTIONS & CAVEATS

  • 5.1 KEY CAVEATS
  • 5.2 CURRENCY CONVERSION
  • 5.3 MARKET DERIVATION

6 MARKET AT A GLANCE

7 INTRODUCTION

  • 7.1 OVERVIEW

8 PREMIUM INSIGHTS

  • 8.1 MARKET SYNOPSIS
    • 8.1.1 MARKET SEGMENTATIONS

9 MARKET OPPORTUNITIES & TRENDS

  • 9.1 RISE IN PRODUCT LAUNCHES & APPROVALS OF BIOSIMILARS
  • 9.2 FAVORABLE POLICIES ENCOURAGING USE OF BIOSIMILARS
  • 9.3 PATENT EXPIRATIONS OF BLOCKBUSTER BRANDED BIOLOGIC DRUGS
  • 9.4 RISING POTENTIAL OF BIOSIMILARS IN EMERGING MARKETS

10 MARKET GROWTH ENABLERS

  • 10.1 FAVORABLE PATIENT DEMOGRAPHICS WITH RISE IN DISEASE BURDEN
  • 10.2 ROBUST PIPELINE OF BIOSIMILARS BOOSTING CONTRACT MANUFACTURING
  • 10.3 RISING INVESTMENTS FOR DEVELOPING BIOSIMILARS
  • 10.4 HIGH COST OF BIOLOGICS & SURGE IN DEMAND FOR BIOSIMILARS

11 MARKET RESTRAINTS

  • 11.1 QUALITY CONTROL AND SUPPLY CHAIN ISSUES WITH CONTRACT MANUFACTURING
  • 11.2 COMPLEXITIES & LIMITATIONS INVOLVED IN MANUFACTURING BIOSIMILARS
  • 11.3 HIGH COST OF ESTABLISHING BIOMANUFACTURING FACILITIES

12 MARKET LANDSCAPE

  • 12.1 MARKET OVERVIEW
  • 12.2 MARKET SIZE & FORECAST
    • 12.2.1 INSIGHTS BY SOURCE
    • 12.2.2 INSIGHTS BY SCALE OF OPERATION
    • 12.2.3 INSIGHTS BY PRODUCT
    • 12.2.4 INSIGHTS BY INDICATION
    • 12.2.5 INSIGHTS BY GEOGRAPHY
  • 12.3 FIVE FORCES ANALYSIS
    • 12.3.1 THREAT OF NEW ENTRANTS
    • 12.3.2 BARGAINING POWER OF SUPPLIERS
    • 12.3.3 BARGAINING POWER OF BUYERS
    • 12.3.4 THREAT OF SUBSTITUTES
    • 12.3.5 COMPETITIVE RIVALRY

13 SOURCE

  • 13.1 MARKET SNAPSHOT & GROWTH ENGINE
  • 13.2 MARKET OVERVIEW
  • 13.3 MAMMALIAN
    • 13.3.1 MARKET OVERVIEW
    • 13.3.2 MARKET SIZE & FORECAST
    • 13.3.3 MAMMALIAN: MARKET BY GEOGRAPHY
  • 13.4 NON-MAMMALIAN
    • 13.4.1 MARKET OVERVIEW
    • 13.4.2 MARKET SIZE & FORECAST
    • 13.4.3 NON-MAMMALIAN: MARKET BY GEOGRAPHY

14 SCALE OF OPERATION

  • 14.1 MARKET SNAPSHOT & GROWTH ENGINE
  • 14.2 MARKET OVERVIEW
  • 14.3 COMMERCIAL
    • 14.3.1 MARKET OVERVIEW
    • 14.3.2 MARKET SIZE & FORECAST
    • 14.3.3 COMMERCIAL: MARKET BY GEOGRAPHY
  • 14.4 RESEARCH
    • 14.4.1 MARKET OVERVIEW
    • 14.4.2 MARKET SIZE & FORECAST
    • 14.4.3 RESEARCH: MARKET BY GEOGRAPHY

15 PRODUCT

  • 15.1 MARKET SNAPSHOT & GROWTH ENGINE
  • 15.2 MARKET OVERVIEW
  • 15.3 FINISHED DOSAGE FORM
    • 15.3.1 MARKET OVERVIEW
    • 15.3.2 MARKET SIZE & FORECAST
    • 15.3.3 FINISHED DOSAGE FORM: MARKET BY GEOGRAPHY
  • 15.4 ACTIVE PHARMACEUTICAL INGREDIENT
    • 15.4.1 MARKET OVERVIEW
    • 15.4.2 MARKET SIZE & FORECAST
    • 15.4.3 ACTIVE PHARMACEUTICAL INGREDIENT: MARKET BY GEOGRAPHY

16 INDICATION

  • 16.1 MARKET SNAPSHOT & GROWTH ENGINE
  • 16.2 MARKET OVERVIEW
  • 16.3 ONCOLOGY
    • 16.3.1 MARKET OVERVIEW
    • 16.3.2 MARKET SIZE & FORECAST
    • 16.3.3 ONCOLOGY: MARKET BY GEOGRAPHY
  • 16.4 BLOOD DISORDERS
    • 16.4.1 MARKET OVERVIEW
    • 16.4.2 MARKET SIZE & FORECAST
    • 16.4.3 BLOOD DISORDERS: MARKET BY GEOGRAPHY
  • 16.5 INFLAMMATORY & AUTOIMMUNE DISORDERS
    • 16.5.1 MARKET OVERVIEW
    • 16.5.2 MARKET SIZE & FORECAST
    • 16.5.3 INFLAMMATORY & AUTOIMMUNE DISORDERS: MARKET BY GEOGRAPHY
  • 16.6 OTHERS
    • 16.6.1 MARKET OVERVIEW
    • 16.6.2 MARKET SIZE & FORECAST
    • 16.6.3 OTHERS: MARKET BY GEOGRAPHY

17 GEOGRAPHY

  • 17.1 MARKET SNAPSHOT & GROWTH ENGINE
  • 17.2 GEOGRAPHIC OVERVIEW

18 EUROPE

  • 18.1 MARKET OVERVIEW
  • 18.2 MARKET SIZE & FORECAST
    • 18.2.1 EUROPE: SOURCE
    • 18.2.2 EUROPE: SCALE OF OPERATION
    • 18.2.3 EUROPE: PRODUCT
    • 18.2.4 EUROPE: INDICATION
  • 18.3 KEY COUNTRIES
    • 18.3.1 GERMANY: MARKET SIZE & FORECAST
    • 18.3.2 FRANCE: MARKET SIZE & FORECAST
    • 18.3.3 UK: MARKET SIZE & FORECAST
    • 18.3.4 ITALY: MARKET SIZE & FORECAST
    • 18.3.5 SPAIN: MARKET SIZE & FORECAST

19 NORTH AMERICA

  • 19.1 MARKET OVERVIEW
  • 19.2 MARKET SIZE & FORECAST
    • 19.2.1 NORTH AMERICA: SOURCE
    • 19.2.2 NORTH AMERICA: SCALE OF OPERATION
    • 19.2.3 NORTH AMERICA: PRODUCT
    • 19.2.4 NORTH AMERICA: INDICATION
  • 19.3 KEY COUNTRIES
    • 19.3.1 US: MARKET SIZE & FORECAST
    • 19.3.2 CANADA: MARKET SIZE & FORECAST

20 APAC

  • 20.1 MARKET OVERVIEW
  • 20.2 MARKET SIZE & FORECAST
    • 20.2.1 APAC: SOURCE
    • 20.2.2 APAC: SCALE OF OPERATION
    • 20.2.3 APAC: PRODUCT
    • 20.2.4 APAC: INDICATION
  • 20.3 KEY COUNTRIES
    • 20.3.1 CHINA: MARKET SIZE & FORECAST
    • 20.3.2 SOUTH KOREA: MARKET SIZE & FORECAST
    • 20.3.3 INDIA: MARKET SIZE & FORECAST
    • 20.3.4 JAPAN: MARKET SIZE & FORECAST
    • 20.3.5 AUSTRALIA: MARKET SIZE & FORECAST

21 LATIN AMERICA

  • 21.1 MARKET OVERVIEW
  • 21.2 MARKET SIZE & FORECAST
    • 21.2.1 LATIN AMERICA: SOURCE
    • 21.2.2 LATIN AMERICA: SCALE OF OPERATION
    • 21.2.3 LATIN AMERICA: PRODUCT
    • 21.2.4 LATIN AMERICA: INDICATION
  • 21.3 KEY COUNTRIES
    • 21.3.1 BRAZIL: MARKET SIZE & FORECAST
    • 21.3.2 MEXICO: MARKET SIZE & FORECAST
    • 21.3.3 ARGENTINA: MARKET SIZE & FORECAST

22 MIDDLE EAST & ARFICA

  • 22.1 MARKET OVERVIEW
  • 22.2 MARKET SIZE & FORECAST
    • 22.2.1 MIDDLE EAST & AFRICA: SOURCE
    • 22.2.2 MIDDLE EAST & AFRICA: SCALE OF OPERATION
    • 22.2.3 MIDDLE EAST & AFRICA: PRODUCT
    • 22.2.4 MIDDLE EAST & AFRICA: INDICATION
  • 22.3 KEY COUNTRIES
    • 22.3.1 TURKEY: MARKET SIZE & FORECAST
    • 22.3.2 SAUDI ARABIA: MARKET SIZE & FORECAST
    • 22.3.3 UAE: MARKET SIZE & FORECAST
    • 22.3.4 SOUTH AFRICA: MARKET SIZE & FORECAST

23 COMPETITIVE LANDSCAPE

  • 23.1 COMPETITION OVERVIEW
  • 23.2 MARKET SHARE ANALYSIS
    • 23.2.1 LONZA IN BIOSIMILAR CONTRACT MANUFACTURING MARKET
    • 23.2.2 BOEHRINGER INGELHEIM INTERNATIONAL GMBH IN BIOSIMILAR CONTRACT MANUFACTURING MARKET
    • 23.2.3 CATALENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET
    • 23.2.4 FUJIFILM DIOSYNTH BIOTECHNOLOGIES IN BIOSIMILAR CONTRACT MANUFACTURING MARKET
    • 23.2.5 THERMO FISHER SCIENTIFIC IN BIOSIMILAR CONTRACT MANUFACTURING MARKET

24 KEY COMPANY PROFILES

  • 24.1 LONZA
    • 24.1.1 BUSINESS OVERVIEW
    • 24.1.2 LONZA IN BIOSIMILAR CONTRACT MANUFACTURING MARKET
    • 24.1.3 PRODUCT OFFERINGS
    • 24.1.4 KEY STRATEGIES
    • 24.1.5 KEY STRENGTHS
    • 24.1.6 KEY OPPORTUNITIES
  • 24.2 BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    • 24.2.1 BUSINESS OVERVIEW
    • 24.2.2 BOEHRINGER INGELHEIM INTERNATIONAL GMBH IN BIOSIMILAR CONTRACT MANUFACTURING MARKET
    • 24.2.3 PRODUCT OFFERINGS
    • 24.2.4 KEY STRATEGIES
    • 24.2.5 KEY STRENGTHS
    • 24.2.6 KEY OPPORTUNITIES
  • 24.3 CATALENT
    • 24.3.1 BUSINESS OVERVIEW
    • 24.3.2 CATALENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET
    • 24.3.3 PRODUCT OFFERINGS
    • 24.3.4 KEY STRATEGIES
    • 24.3.5 KEY STRENGTHS
    • 24.3.6 KEY OPPORTUNITIES
  • 24.4 FUJIFILM
    • 24.4.1 BUSINESS OVERVIEW
    • 24.4.2 FUJIFILM IN BIOSIMILAR CONTRACT MANUFACTURING MARKET
    • 24.4.3 PRODUCT OFFERINGS
    • 24.4.4 KEY STRATEGIES
    • 24.4.5 KEY STRENGTHS
    • 24.4.6 KEY OPPORTUNITIES
  • 24.5 THERMO FISHER SCIENTIFIC
    • 24.5.1 BUSINESS OVERVIEW
    • 24.5.2 THERMO FISHER SCIENTIFIC IN BIOSIMILAR CONTRACT MANUFACTURING MARKET
    • 24.5.3 PRODUCT OFFERINGS
    • 24.5.4 KEY STRATEGIES
    • 24.5.5 KEY STRENGTHS
    • 24.5.6 KEY OPPORTUNITIES

25 OTHER PROMINENT VENDORS

  • 25.1 ABBVIE
    • 25.1.1 BUSINESS OVERVIEW
    • 25.1.2 SERVICE OFFERINGS
  • 25.2 ABZENA
    • 25.2.1 BUSINESS OVERVIEW
    • 25.2.2 SERVICE OFFERINGS
  • 25.3 AGC BIOLOGICS
    • 25.3.1 BUSINESS OVERVIEW
    • 25.3.2 SERVICE OFFERINGS
  • 25.4 ALCAMI
    • 25.4.1 BUSINESS OVERVIEW
    • 25.4.2 SERVICE OFFERINGS
  • 25.5 ALMAC GROUP
    • 25.5.1 BUSINESS OVERVIEW
    • 25.5.2 SERVICE OFFERINGS
  • 25.6 AVID BIOSERVICES
    • 25.6.1 BUSINESS OVERVIEW
    • 25.6.2 SERVICE OFFERINGS
  • 25.7 BIOCON
    • 25.7.1 BUSINESS OVERVIEW
    • 25.7.2 SERVICE OFFERINGS
  • 25.8 ELEMENT MATERIALS TECHNOLOGY
    • 25.8.1 BUSINESS OVERVIEW
    • 25.8.2 SERVICE OFFERINGS
  • 25.9 EUROFINS SCIENTIFIC
    • 25.9.1 BUSINESS OVERVIEW
    • 25.9.2 SERVICE OFFERINGS
  • 25.10 FRESENIUS KABI
    • 25.10.1 BUSINESS OVERVIEW
    • 25.10.2 SERVICE OFFERINGS
  • 25.11 GOODWIN BIOTECHNOLOGY
    • 25.11.1 BUSINESS OVERVIEW
    • 25.11.2 SERVICE OFFERINGS
  • 25.12 KEMWELL
    • 25.12.1 BUSINESS OVERVIEW
    • 25.12.2 SERVICE OFFERINGS
  • 25.13 MABXIENCE
    • 25.13.1 BUSINESS OVERVIEW
    • 25.13.2 SERVICE OFFERINGS
  • 25.14 MERCK KGAA
    • 25.14.1 BUSINESS OVERVIEW
    • 25.14.2 SERVICE OFFERINGS
  • 25.15 MIDAS PHARMA
    • 25.15.1 BUSINESS OVERVIEW
    • 25.15.2 SERVICE OFFERINGS
  • 25.16 NOVARTIS AG
    • 25.16.1 BUSINESS OVERVIEW
    • 25.16.2 SERVICE OFFERINGS
  • 25.17 PFIZER
    • 25.17.1 BUSINESS OVERVIEW
    • 25.17.2 SERVICE OFFERINGS
  • 25.18 RENTSCHLER BIOPHARMA
    • 25.18.1 BUSINESS OVERVIEW
    • 25.18.2 SERVICE OFFERINGS
  • 25.19 SAMSUNG BIOLOGICS
    • 25.19.1 BUSINESS OVERVIEW
    • 25.19.2 SERVICE OFFERINGS
  • 25.20 WUXI BIOLOGICS
    • 25.20.1 BUSINESS OVERVIEW
    • 25.20.2 SERVICE OFFERINGS

26 REPORT SUMMARY

  • 26.1 KEY TAKEAWAYS
  • 26.2 STRATEGIC RECOMMENDATIONS

27 QUANTITATIVE SUMMARY

  • 27.1 MARKET BY SOURCE
    • 27.1.1 EUROPE BY SOURCE SEGMENTATION
    • 27.1.2 NORTH AMERICA BY SOURCE SEGMENTATION
    • 27.1.3 APAC BY SOURCE SEGMENTATION
    • 27.1.4 LATIN AMERICA BY SOURCE SEGMENTATION
    • 27.1.5 MIDDLE EAST & AFRICA BY SOURCE SEGMENTATION
  • 27.2 MARKET BY SCALE OF OPERATION
    • 27.2.1 EUROPE BY SCALE OF OPERATION SEGMENTATION
    • 27.2.2 NORTH AMERICA BY SCALE OF OPERATION
    • 27.2.3 APAC BY SCALE OF OPERATION SEGMENTATION
    • 27.2.4 LATIN AMERICA BY SCALE OF OPERATION
    • 27.2.5 MIDDLE EAST AFRICA BY SCALE OF OPERATION SEGMENTATION
  • 27.3 MARKET BY PRODUCT
    • 27.3.1 EUROPE BY PRODUCT SEGMENTATION
    • 27.3.2 NORTH AMERICA BY PRODUCT SEGMENTATION
    • 27.3.3 APAC BY PRODUCT SEGMENTATION
    • 27.3.4 LATIN AMERICA BY PRODUCT SEGMENTATION
    • 27.3.5 MIDDLE EAST & AFRICA BY PRODUCT SEGMENTATION
  • 27.4 MARKET BY INDICATION
    • 27.4.1 EUROPE BY INIDCATION SEGMENTATION
    • 27.4.2 NORTH AMERICA BY INIDCATION SEGMENTATION
    • 27.4.3 APAC BY INIDCATION SEGMENTATION
    • 27.4.4 LATIN AMERICA BY INIDCATION SEGMENTATION
    • 27.4.5 MIDDLE EAST & AFRICA BY INIDCATION SEGMENTATION
  • 27.5 MARKET BY GEOGRAPHY
    • 27.5.1 MAMMALIAN SEGMENT BY GEOGRAPHY
    • 27.5.2 NON-MAMMALIAN SEGMENT BY GEOGRAPHY
    • 27.5.3 COMMERCIAL SEGMENT BY GEOGRAPHY
    • 27.5.4 RESEARCH SEGMENT BY GEOGRAPHY
    • 27.5.5 FINISHED DOSAGE FORM SEGMENT BY GEOGRAPHY
    • 27.5.6 ACTIVE PHARMACEUTICAL INGREDIENTS BY GEOGRAPHY
    • 27.5.7 ONCOLOGY SEGMENT BY GEOGRAPHY
    • 27.5.8 BLOOD DISORDERS SEGMENT BY GEOGRAPHY
    • 27.5.9 INFLAMMATION & AUTOIMMUNE DISORDERS SEGMENT BY GEOGRAPHY
    • 27.5.10 OTHERS BY GEOGRAPHY

28 APPENDIX

  • 28.1 ABBREVIATIONS
Product Code: ARZ221113

LIST OF EXHIBITS

  • EXHIBIT 1 SEGMENTATION OF GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET
  • EXHIBIT 2 MARKET SIZE CALCULATION APPROACH 2021
  • EXHIBIT 3 NUMBER OF BIOSIMILAR PRODUCT AUTHORIZATIONS IN US AND EUROPE
  • EXHIBIT 4 ESTIMATED PATENT EXPIRATIONS OF BIOLOGICS ACROSS VARIOUS REGIONS
  • EXHIBIT 5 BIOSIMILAR PIPELINE BY PHASES OF DEVELOPMENT (2013 & 2020)
  • EXHIBIT 6 IMPACT OF RISE IN PRODUCT LAUNCHES & APPROVALS OF BIOSIMILARS
  • EXHIBIT 7 LAUNCHES & APPROVALS OF BIOSIMILARS IN US (2015-2021)
  • EXHIBIT 8 BIOSIMILAR PRODUCT AUTHORIZATIONS IN US AND EUROPE
  • EXHIBIT 9 LAUNCHES OF NEW & UPCOMING BIOSIMILARS IN US
  • EXHIBIT 10 IMPACT OF FAVORABLE POLICIES ENCOURAGING USE OF BIOSIMILARS
  • EXHIBIT 11 IMPACT OF PATENT EXPIRATIONS OF BLOCKBUSTER BRANDED BIOLOGIC DRUGS
  • EXHIBIT 12 ESTIMATED PATENT EXPIRATIONS OF BIOLOGICS ACROSS VARIOUS REGIONS
  • EXHIBIT 13 IMPACT OF RISING POTENTIAL OF BIOSIMILARS IN EMERGING MARKETS
  • EXHIBIT 14 GROWTH OF BIOSIMILAR SHARES IN EMERGING MARKETS
  • EXHIBIT 15 IMPACT OF FAVORABLE PATIENT DEMOGRAPHICS WITH RISE IN DISEASE BURDEN
  • EXHIBIT 16 GLOBAL STATISTICS OF MAJOR AUTOIMMUNE DISEASES (2021)
  • EXHIBIT 17 ESTIMATED PERCENTAGE OF MAJOR CANCERS WORLDWIDE (2022)
  • EXHIBIT 18 IMPACT OF ROBUST PIPELINE OF BIOSIMILARS BOOSTING CONTRACT MANUFACTURING
  • EXHIBIT 19 BIOSIMILAR PIPELINE BY PHASES OF DEVELOPMENT (2013 & 2020)
  • EXHIBIT 20 PIPELINE OF BIOSIMILARS IN VARIOUS COUNTRIES OR REGIONS
  • EXHIBIT 21 TOP BIOSIMILAR COMPANIES WITH THEIR TOTAL & PIPELINE BIOSIMILAR PRODUCTS
  • EXHIBIT 22 IMPACT OF RISING INVESTMENTS FOR DEVELOPING BIOSIMILARS
  • EXHIBIT 23 IMPACT OF HIGH COST OF BIOLOGICS & SURGE IN DEMAND FOR BIOSIMILARS
  • EXHIBIT 24 CHANGE IN PRICES AFTER INTRODUCTION OF BIOSIMILAR ACCESSIBLE MARKET
  • EXHIBIT 25 IMPACT OF QUALITY CONTROL AND SUPPLY CHAIN ISSUES WITH CONTRACT MANUFACTURING
  • EXHIBIT 26 MAJOR BARRIERS TO EFFECTIVE VACCINE HANDLING AND STORAGE
  • EXHIBIT 27 IMPACT OF COMPLEXITIES & LIMITATIONS INVOLVED IN MANUFACTURING BIOSIMILARS
  • EXHIBIT 28 IMPACT OF HIGH COST OF ESTABLISHING BIOMANUFACTURING FACILITIES
  • EXHIBIT 29 TOP 10 GLOBAL MANUFACTURING HUBS
  • EXHIBIT 30 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 31 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE
  • EXHIBIT 32 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION
  • EXHIBIT 33 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT
  • EXHIBIT 34 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION
  • EXHIBIT 35 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY
  • EXHIBIT 36 FIVE FORCES ANALYSIS 2021
  • EXHIBIT 37 INCREMENTAL GROWTH BY SOURCE 2021 & 2027
  • EXHIBIT 38 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE
  • EXHIBIT 39 NUMBER OF BIOSIMILARS IN PIPELINE DISTRIBUTED BY PHASE AND PRODUCTION TECHNOLOGY 2019
  • EXHIBIT 40 VARIOUS CELL LINE EXPRESSION SYSTEMS OFFERED BY CONTRACT MANUFACTURERS
  • EXHIBIT 41 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE: INCREMENTAL GROWTH
  • EXHIBIT 42 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE: ABSOLUTE GROWTH
  • EXHIBIT 43 GLOBAL MAMMALIAN BIOSIMILAR CONTRACT MANUFACTURING MARKET: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 44 ORIGINATORS AND PRODUCTS OF MAMMALIAN-BASED BIOSIMILAR TARGETS DISTRIBUTED BY PHASE
  • EXHIBIT 45 GLOBAL MAMMALIAN BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 46 INCREMENTAL GROWTH BY GEOGRAPHY 2021 & 2027
  • EXHIBIT 47 GLOBAL NON-MAMMALIAN BIOSIMILAR CONTRACT MANUFACTURING MARKET: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 48 ORIGINATORS AND PRODUCTS OF MICROBIAL-BASED BIOSIMILAR TARGETS DISTRIBUTED BY PHASE
  • EXHIBIT 49 GLOBAL NON-MAMMALIAN BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 50 INCREMENTAL GROWTH BY GEOGRAPHY 2021 & 2027
  • EXHIBIT 51 INCREMENTAL GROWTH BY SCALE OF OPERATION 2021 & 2027
  • EXHIBIT 52 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION
  • EXHIBIT 53 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION: INCREMENTAL GROWTH
  • EXHIBIT 54 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION: ABSOLUTE GROWTH
  • EXHIBIT 55 GLOBAL COMMERCIAL BIOSIMILAR CONTRACT MANUFACTURING MARKET: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 56 GLOBAL COMMERCIAL BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 57 INCREMENTAL GROWTH BY GEOGRAPHY 2021 & 2027
  • EXHIBIT 58 GLOBAL RESEARCH BIOSIMILAR CONTRACT MANUFACTURING MARKET: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 59 GLOBAL RESEARCH BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 60 INCREMENTAL GROWTH BY GEOGRAPHY 2021 & 2027
  • EXHIBIT 61 INCREMENTAL GROWTH BY PRODUCT 2021 & 2027
  • EXHIBIT 62 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT
  • EXHIBIT 63 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT: INCREMENTAL GROWTH
  • EXHIBIT 64 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT: ABSOLUTE GROWTH
  • EXHIBIT 65 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY FINISHED DOSAGE FORM: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 66 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY FINISHED DOSAGE FORM 2021-2027 ($ MILLION)
  • EXHIBIT 67 INCREMENTAL GROWTH BY GEOGRAPHY 2021 & 2027
  • EXHIBIT 68 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY ACTIVE PHARMACEUTICAL INGREDIENT: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 69 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY ACTIVE PHARMACEUTICAL INGREDIENT 2021-2027 ($ MILLION)
  • EXHIBIT 70 INCREMENTAL GROWTH BY GEOGRAPHY 2021 & 2027
  • EXHIBIT 71 INCREMENTAL GROWTH BY INDICATION 2021 & 2027
  • EXHIBIT 72 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION
  • EXHIBIT 73 EMA- & FDA-APPROVED BIOSIMILARS BY THERAPEUTIC AREA (2019)
  • EXHIBIT 74 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION: INCREMENTAL GROWTH
  • EXHIBIT 75 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION: ABSOLUTE GROWTH
  • EXHIBIT 76 GLOBAL ONCOLOGY BIOSIMILAR CONTRACT MANUFACTURING MARKET: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 77 EXPIRED PATENTS OF ONCOLOGY BIOLOGIC DRUGS IN US & EUROPE
  • EXHIBIT 78 FDA-APROVED BIOSIMILARS FOR ONCOLOGY TREATMENT
  • EXHIBIT 79 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY ONCOLOGY 2021-2027 ($ MILLION)
  • EXHIBIT 80 INCREMENTAL GROWTH BY GEOGRAPHY 2021 & 2027
  • EXHIBIT 81 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY BLOOD DISORDERS: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 82 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY BLOOD DISORDERS 2021-2027 ($ MILLION)
  • EXHIBIT 83 INCREMENTAL GROWTH BY GEOGRAPHY 2021 & 2027
  • EXHIBIT 84 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INFLAMMATORY & AUTOIMMUNE DISORDERS: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 85 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INFLAMMATORY & AUTOIMMUNE DISORDERS 2021-2027 ($ MILLION)
  • EXHIBIT 86 INCREMENTAL GROWTH BY GEOGRAPHY 2021 & 2027
  • EXHIBIT 87 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY OTHER INDICATIONS: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 88 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY OTHER INDICATIONS 2021-2027 ($ MILLION)
  • EXHIBIT 89 INCREMENTAL GROWTH BY GEOGRAPHY 2021 & 2027
  • EXHIBIT 90 INCREMENTAL GROWTH BY GEOGRAPHY 2021 & 2027
  • EXHIBIT 91 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY
  • EXHIBIT 92 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY: KEY COUNTRIES (2021)
  • EXHIBIT 93 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY: INCREMENTAL GROWTH
  • EXHIBIT 94 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY: ABSOLUTE GROWTH
  • EXHIBIT 95 EUROPE BIOSIMILAR CONTRACT MANUFACTURING MARKET: KEY COUNTRIES (2021)
  • EXHIBIT 96 EUROPE BIOSIMILAR CONTRACT MANUFACTURING MARKET: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 97 EUROPE BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 98 INCREMENTAL GROWTH BY SOURCE 2021 & 2027
  • EXHIBIT 99 INCREMENTAL GROWTH BY SCALE OF OPERATION 2021 & 2027
  • EXHIBIT 100 INCREMENTAL GROWTH BY PRODUCT 2021 & 2027
  • EXHIBIT 101 INCREMENTAL GROWTH BY INDICATION 2021 & 2027
  • EXHIBIT 102 INCREMENTAL GROWTH IN EUROPE 2021 & 2027
  • EXHIBIT 103 GERMANY BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 104 FRANCE BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 105 UK BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 106 ITALY BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 107 SPAIN BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 108 NORTH AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET: KEY COUNTRIES (2021)
  • EXHIBIT 109 NORTH AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 110 NORTH AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 111 INCREMENTAL GROWTH BY SOURCE 2021 & 2027
  • EXHIBIT 112 INCREMENTAL GROWTH BY SCALE OF OPERATION 2021 & 2027
  • EXHIBIT 113 INCREMENTAL GROWTH BY PRODUCT 2021 & 2027
  • EXHIBIT 114 INCREMENTAL GROWTH BY INDICATION 2021 & 2027
  • EXHIBIT 115 INCREMENTAL GROWTH IN NORTH AMERICA 2021 & 2027
  • EXHIBIT 116 US BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 117 CANADA BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 118 APAC BIOSIMILAR CONTRACT MANUFACTURING MARKET: KEY COUNTRIES (2021)
  • EXHIBIT 119 APAC BIOSIMILAR CONTRACT MANUFACTURING MARKET: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 120 APAC BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 121 INCREMENTAL GROWTH BY SOURCE 2021 & 2027
  • EXHIBIT 122 INCREMENTAL GROWTH BY SCALE OF OPERATION 2021 & 2027
  • EXHIBIT 123 INCREMENTAL GROWTH BY PRODUCT 2021 & 2027
  • EXHIBIT 124 INCREMENTAL GROWTH BY INDICATION 2021 & 2027
  • EXHIBIT 125 INCREMENTAL GROWTH IN APAC 2021 & 2027
  • EXHIBIT 126 CHINA BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 127 SOUTH KOREA BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 128 INDIA BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 129 JAPAN BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 130 AUSTRALIA BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 131 LATIN AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET: KEY COUNTRIES (2021)
  • EXHIBIT 132 LATIN AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 133 LATIN AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 134 INCREMENTAL GROWTH BY SOURCE 2021 & 2027
  • EXHIBIT 135 INCREMENTAL GROWTH BY SCALE OF OPERATION 2021 & 2027
  • EXHIBIT 136 INCREMENTAL GROWTH BY PRODUCT 2021 & 2027
  • EXHIBIT 137 INCREMENTAL GROWTH BY INDICATION 2021 & 2027
  • EXHIBIT 138 INCREMENTAL GROWTH IN LATIN AMERICA 2021 & 2027
  • EXHIBIT 139 BRAZIL BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 140 MEXICO BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 141 ARGENTINA BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 142 MIDDLE EAST & AFRICA BIOSIMILAR CONTRACT MANUFACTURING MARKET: KEY COUNTRIES (2021)
  • EXHIBIT 143 MIDDLE EAST & AFRICA BIOSIMILAR CONTRACT MANUFACTURING MARKET: INCREMENTAL & ABSOLUTE GROWTH
  • EXHIBIT 144 MIDDLE EAST & AFRICA BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 145 INCREMENTAL GROWTH BY SOURCE 2021 & 2027
  • EXHIBIT 146 INCREMENTAL GROWTH BY SCALE OF OPERATION 2021 & 2027
  • EXHIBIT 147 INCREMENTAL GROWTH BY PRODUCT 2021 & 2027
  • EXHIBIT 148 INCREMENTAL GROWTH BY INDICATION 2021 & 2027
  • EXHIBIT 149 INCREMENTAL GROWTH IN MIDDLE EAST & AFRICA 2021 & 2027
  • EXHIBIT 150 TURKEY BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 151 SAUDI ARABIA BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 152 UAE BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 153 SOUTH AFRICA BIOSIMILAR CONTRACT MANUFACTURING MARKET 2021-2027 ($ MILLION)
  • EXHIBIT 154 LONZA: TOTAL REVENUE 2019-2021 ($ MILLION)
  • EXHIBIT 155 LONZA: REVENUE BY BUSINESS SEGMENT 2020-2021 ($ MILLION)
  • EXHIBIT 156 LONZA: TOTAL R&D EXPENDITURE 2019-2021 ($ MILLION)
  • EXHIBIT 157 LONZA: REVENUE BY GEOGRAPHIC REGION 2020-2021 ($ MILLION)
  • EXHIBIT 158 BOEHRINGER INGELHEIM INTERNATIONAL GMBH: TOTAL REVENUE 2019-2021 ($ BILLION)
  • EXHIBIT 159 BOEHRINGER INGELHEIM INTERNATIONAL GMBH: REVENUE BY BUSINESS SEGMENT 2019-2021 ($ BILLION)
  • EXHIBIT 160 BOEHRINGER INGELHEIM INTERNATIONAL GMBH: TOTAL R&D EXPENDITURE 2019-2021 ($ BILLION)
  • EXHIBIT 161 BOEHRINGER INGELHEIM INTERNATIONAL GMBH: REVENUE BY GEOGRAPHIC REGION 2019-2021 ($ BILLION)
  • EXHIBIT 162 CATALENT: TOTAL REVENUE 2019-2021 ($ MILLION)
  • EXHIBIT 163 FUJIFILM: TOTAL REVENUE 2018-2020 ($ BILLION)
  • EXHIBIT 164 FUJIFILM: REVENUE BY BUSINESS SEGMENT 2019-2020 ($ BILLION)
  • EXHIBIT 165 THERMO FISHER SCIENTIFIC: TOTAL REVENUE 2019-2021 ($ MILLION)
  • EXHIBIT 166 THERMO FISHER SCIENTIFIC: REVENUE BY BUSINESS SEGMENT 2020-2021 ($ MILLION)
  • EXHIBIT 167 THERMO FISHER SCIENTIFIC: R&D EXPENDITURE 2019-2021 ($ MILLION)
  • EXHIBIT 168 THERMO FISHER SCIENTIFIC: REVENUE BY GEOGRAPHY 2021 ($ MILLION)

LIST OF TABLES

  • TABLE 1 KEY CAVEATS
  • TABLE 2 CURRENCY CONVERSION 2015-2021
  • TABLE 3 PATENT EXPIRATION OF MAJOR BIOLOGICS BY THERAPEUTIC AREA
  • TABLE 4 NUMBER OF BIOSIMILARS IN DEVELOPMENTAL PIPELINE (2017 & 2019)
  • TABLE 5 BIOSIMILARS APPROVED BY FDA & EMA (BY INDICATION)
  • TABLE 6 LONZA: MAJOR PRODUCT OFFERINGS
  • TABLE 7 BOEHRINGER INGELHEIM INTERNATIONAL GMBH: MAJOR PRODUCT OFFERINGS
  • TABLE 8 CATALENT: MAJOR PRODUCT OFFERINGS
  • TABLE 9 FUJIFILM: MAJOR PRODUCT OFFERINGS
  • TABLE 10 THERMO FISHER SCIENTIFIC: MAJOR PRODUCT OFFERINGS
  • TABLE 11 ABBVIE: MAJOR SERVICE OFFERINGS
  • TABLE 12 ABZENA: MAJOR SERVICE OFFERINGS
  • TABLE 13 AGC BIOLOGICS: MAJOR SERVICE OFFERINGS
  • TABLE 14 ALCAMI: MAJOR SERVICE OFFERINGS
  • TABLE 15 ALMAC GROUP: MAJOR SERVICE OFFERINGS
  • TABLE 16 AVID BIOSERVICES: MAJOR SERVICE OFFERINGS
  • TABLE 17 BIOCON: MAJOR SERVICE OFFERINGS
  • TABLE 18 ELEMENT MATERIALS TECHNOLOGY: MAJOR SERVICE OFFERINGS
  • TABLE 19 EUROFINS SCIENTIFIC: MAJOR SERVICE OFFERINGS
  • TABLE 20 FRESENIUS KABI: MAJOR SERVICE OFFERINGS
  • TABLE 21 GOODWIN BIOTECHNOLOGY: MAJOR SERVICE OFFERINGS
  • TABLE 22 KEMWELL: MAJOR SERVICE OFFERINGS
  • TABLE 23 MABXIENCE: MAJOR SERVICE OFFERINGS
  • TABLE 24 MERCK KGAA: MAJOR SERVICE OFFERINGS
  • TABLE 25 MIDAS PHARMA: MAJOR SERVICE OFFERINGS
  • TABLE 26 NOVARTIS AG: MAJOR SERVICE OFFERINGS
  • TABLE 27 PFIZER: MAJOR SERVICE OFFERINGS
  • TABLE 28 RENTSCHLER BIOPHARMA: MAJOR SERVICE OFFERINGS
  • TABLE 29 SAMSUNG BIOLOGICS: MAJOR SERVICE OFFERINGS
  • TABLE 30 WUXI BIOLOGICS: MAJOR SERVICE OFFERINGS
  • TABLE 31 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE 2021-2027 ($ MILLION)
  • TABLE 32 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE 2021-2027 (%)
  • TABLE 33 EUROPE BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE 2021-2027 ($ MILLION)
  • TABLE 34 EUROPE BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE 2021-2027 (%)
  • TABLE 35 NORTH AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE 2021-2027 ($ MILLION)
  • TABLE 36 NORTH AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE 2021-2027 (%)
  • TABLE 37 APAC BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE 2021-2027 ($ MILLION)
  • TABLE 38 APAC BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE 2021-2027 (%)
  • TABLE 39 LATIN AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE 2021-2027 ($ MILLION)
  • TABLE 40 LATIN AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE 2021-2027 (%)
  • TABLE 41 MIDDLE EAST & AFRICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE 2021-2027 ($ MILLION)
  • TABLE 42 MIDDLE EAST & AFRICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SOURCE 2021-2027 (%)
  • TABLE 43 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION 2021-2027 ($ MILLION)
  • TABLE 44 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION 2021-2027 (%)
  • TABLE 45 EUROPE BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION 2021-2027 ($ MILLION)
  • TABLE 46 EUROPE BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION 2021-2027 (%)
  • TABLE 47 NORTH AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION 2021-2027 ($ MILLION)
  • TABLE 48 NORTH AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION 2021-2027 (%)
  • TABLE 49 APAC BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION 2021-2027 ($ MILLION)
  • TABLE 50 APAC BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION 2021-2027 (%)
  • TABLE 51 LATIN AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION 2021-2027 ($ MILLION)
  • TABLE 52 LATIN AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION 2021-2027 (%)
  • TABLE 53 MIDDLE EAST AFRICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION 2021-2027 ($ MILLION)
  • TABLE 54 MIDDLE EAST & AFRICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY SCALE OF OPERATION 2021-2027 (%)
  • TABLE 55 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT 2021-2027 ($ MILLION)
  • TABLE 56 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT 2021-2027 (%)
  • TABLE 57 EUROPE BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT 2021-2027 ($ MILLION)
  • TABLE 58 EUROPE BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT 2021-2027 (%)
  • TABLE 59 NORTH AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT 2021-2027 ($ MILLION)
  • TABLE 60 NORTH AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT 2021-2027 (%)
  • TABLE 61 APAC BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT 2021-2027 ($ MILLION)
  • TABLE 62 APAC BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT 2021-2027 (%)
  • TABLE 63 LATIN AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT 2021-2027 ($ MILLION)
  • TABLE 64 LATIN AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT 2021-2027 (%)
  • TABLE 65 MIDDLE EAST & AFRICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT 2021-2027 ($ MILLION)
  • TABLE 66 MIDDLE EAST & AFRICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY PRODUCT 2021-2027 (%)
  • TABLE 67 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION 2021-2027 ($ MILLION)
  • TABLE 68 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION 2021-2027 (%)
  • TABLE 69 EUROPE BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION 2021-2027 ($ MILLION)
  • TABLE 70 EUROPE BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION 2021-2027 (%)
  • TABLE 71 NORTH AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION 2021-2027 ($ MILLION)
  • TABLE 72 NORTH AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION 2021-2027 (%)
  • TABLE 73 APAC BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION 2021-2027 ($ MILLION)
  • TABLE 74 APAC BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION 2021-2027 (%)
  • TABLE 75 LATIN AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION 2021-2027 ($ MILLION)
  • TABLE 76 LATIN AMERICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION 2021-2027 (%)
  • TABLE 77 MIDDLE EAST & AFRICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION 2021-2027 ($ MILLION)
  • TABLE 78 MIDDLE EAST & AFRICA BIOSIMILAR CONTRACT MANUFACTURING MARKET BY INDICATION 2021-2027 (%)
  • TABLE 79 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 ($ MILLION)
  • TABLE 80 GLOBAL BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 (%)
  • TABLE 81 MAMMALIAN SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 ($ MILLION)
  • TABLE 82 MAMMALIAN SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 (%)
  • TABLE 83 NON-MAMMALIAN SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021- 2027 ($ MILLION)
  • TABLE 84 NON-MAMMALIAN SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 (%)
  • TABLE 85 COMMERCIAL SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 ($ MILLION)
  • TABLE 86 COMMERCIAL SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 (%)
  • TABLE 87 RESEARCH SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 ($ MILLION)
  • TABLE 88 RESEARCH SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 (%)
  • TABLE 89 FINISHED DOSAGE FORM SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 ($ MILLION)
  • TABLE 90 FINISHED DOSAGE FORM SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 (%)
  • TABLE 91 ACTIVE PHARMACEUTICAL INGREDIENTS SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 ($ MILLION)
  • TABLE 92 ACTIVE PHARMACEUTICAL INGREDIENTS SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 (%)
  • TABLE 93 ONCOLOGY SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 ($ MILLION)
  • TABLE 94 ONCOLOGY SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 (%)
  • TABLE 95 BLOOD DISORDERS SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 ($ MILLION)
  • TABLE 96 BLOOD DISORDERS SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021- 2027 (%)
  • TABLE 97 INFLAMMATION & AUTOIMMUNE DISORDERS SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 ($ MILLION)
  • TABLE 98 INFLAMMATION & AUTOIMMUNE DISORDERS SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 (%)
  • TABLE 99 OTHERS SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 ($ MILLION)
  • TABLE 100 OTHERS SEGMENT IN BIOSIMILAR CONTRACT MANUFACTURING MARKET BY GEOGRAPHY 2021-2027 (%)
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