PUBLISHER: Coherent Market Insights | PRODUCT CODE: 1122413
PUBLISHER: Coherent Market Insights | PRODUCT CODE: 1122413
Fibromyalgia is a common and complex chronic pain disorder that causes musculoskeletal pain, fatigue, and localized tenderness affecting individuals mentally, physically, and socially. Fibromyalgia is mainly caused due to genetic conditions, however actual cause is still unknown. The most common symptoms of fibromyalgia are fatigue, sleeping problems, chronic muscle pain, and tender points. An individual with fibromyalgia can also have symptoms such as headaches, muscle pain, burning, twitching, or tightness, poor concentration, draining fatigue and depression. Fibromyalgia symptoms might accumulate with time or it can be caused by some external factors. Fibromyalgia treatments include therapy, medications, regular aerobic exercise, stress reduction, and others. Furthermore, for the treatment of fibromyalgia, antidepressants or pain medications are prescribed to treat depression, anxiety, pain, and fatigue. The FM/a Test is a blood test used for the diagnosis of fibromyalgia. It is available for use in patients of any age who have at least four of the typical symptoms of fibromyalgia. The three drugs approved specifically for fibro pain are Duloxetine (Cymbalta), Milnacipran (Savella), Pregabalin (Lyrica). Over-the-counter painkillers are used in treating fibromyalgia. Stronger medicines, like opioids,are not prescribed for long term use, and you could become dependent on them.
Key players in the market are focusing on research and development activities for the development of novel medications for fibromyalgia treatment. Launch of novel drugs in the market for fibromyalgia is expected to boost the fibromyalgia treatment market growth over the forecast period.
For instance, in December 2018, Aptinyx Inc., Biotech Company announced positive results from an interim analysis of an exploratory study of its novel NMDA receptor (NMDAr) modulator, NYX-2925, in subjects with fibromyalgia. Subjects in the study received daily oral doses of NYX-2925 at two dose levels, 20 mg and 200 mg, as well as placebo, over the course of six weeks.
In 2017, Virios Therapeutics, Biotechnology company announced that the Journal of Pain Research published the key topline results from the Phase 2 PRID-201 trial of IMC-1 for the treatment of fibromyalgia. This 16 week, randomized double-blinded, placebo-controlled study was conducted at 12 research centers in the U.S. and enrolled 143 patients with fibromyalgia, as defined by the ACR 2010 criteria. The PRID-201 study demonstrated that patients randomized to IMC-1 (celecoxib+famciclovir) experienced a significant decrease in fibromyalgia-related pain vs patients randomized to placebo.
Moreover, over the past few years, leading generic manufacturers such as Sun Pharmaceutical Industries Ltd., Mylan N.V., and Teva Pharmaceuticals Industries Ltd. launched generic drugs for fibromyalgia treatment in the market.
Furthermore, in September 2021, University of Alabama at Birmingham, carried out a study to evaluate if Dextromethorphan (DXM) reduces Fibromyalgia (FM) pain. Dextromethorphan (DXM) is a drug found in several over-the-counter products, including cough suppressants. The drug may reduce Fibromyalgia (FM) pain by suppressing inflammation in the central nervous system. The Dextromethorphan (DXM) is still in phase 2 trial.
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