Market Research Report
Complement C1s inhibitors - Pipeline Insight, 2022
|Complement C1s inhibitors - Pipeline Insight, 2022|
DelveInsight Business Research LLP
Content info: 60 Pages
Delivery time: 2-10 business days
DelveInsight's, " Complement C1s inhibitors - Pipeline Insight, 2022" report provides comprehensive insights about 4+ companies and 4+ pipeline drugs in Complement C1s inhibitors pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Complement C1s inhibitors Understanding
Complement C1s inhibitors: Overview
C1 inhibitor is a broad-spectrum serpin that inhibits the activated forms of several members of the complement pathway (C1r and C1s), the contact system (FXIIa, FXIa, and kallikrein) as well as fibrinolytic proteases (plasmin, tPA and uPA). C1-INH binds covalently to C1r and C1s, leading to dissociation of the C1 macromolecular complex and inhibition of the enzymatic actions of C1r and C1s. Several C1 inhibitors targeting C1s are progressing towards clinical trials.
" Complement C1s inhibitors - Pipeline Insight, 2022" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Complement C1s inhibitors pipeline landscape is provided which includes the disease overview and Complement C1s inhibitors treatment guidelines. The assessment part of the report embraces, in depth Complement C1s inhibitors commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Complement C1s inhibitors collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Complement C1s inhibitors Emerging Drugs Chapters
This segment of the Complement C1s inhibitors report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Complement C1s inhibitors Emerging Drugs
Sutimlimab, formerly known as BIVV009 or TNT009, is an investigational monoclonal antibody that causes selective blockade of complement C1, a protein with an integral role in the classical complement pathway. This pathway is overactivated in cold agglutinin disease (CAD). By blocking C1, sutimlimab treats the underlying cause of hemolysis, thus preventing hemolytic anemia and reducing the disease burden. The U.S. Food and Drug Administration (FDA) has issued a complete response to Sanofi's application requesting that its investigational therapy sutimlimab be approved for treating hemolysis - the breakdown of red blood cells - in adults with cold agglutinin disease (CAD). The U.S. Food and Drug Administration (FDA) has issued a complete response to Sanofi's application requesting that its investigational therapy sutimlimab be approved for treating hemolysis - the breakdown of red blood cells - in adults with cold agglutinin disease (CAD). While the complete response letter did not report any issues regarding clinical data on the therapy's safety and effectiveness, which were provided in Sanofi's biologics license application, it referred to "certain deficiencies" detected by the agency during a pre-license inspection of a third-party manufacturing facility.
Further product details are provided in the report……..
Complement C1s inhibitors: Therapeutic Assessment
This segment of the report provides insights about the different Complement C1s inhibitors drugs segregated based on following parameters that define the scope of the report, such as:
There are approx. 4+ key companies which are developing the therapies for Complement C1s inhibitors. The companies which have their Complement C1s inhibitors drug candidates in the most advanced stage, i.e. preregistration include Bioverativ.
DelveInsight's report covers around 4+ products under different phases of clinical development like
Complement C1s inhibitors pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Products have been categorized under various Molecule types such as
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
Complement C1s inhibitors: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Complement C1s inhibitors therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Complement C1s inhibitors drugs.
Current Treatment Scenario and Emerging Therapies: