DelveInsight's 'Hereditary Angioedema (HAE)- Epidemiology Forecast-2032' report delivers an in-depth understanding of HAE, historical and forecasted epidemiology as well as HAE trends in the United States, the EU5 (Germany, France, Italy, Spain) and the United Kingdom, Japan, and China.
Hereditary Angioedema (HAE) Disease Understanding
Hereditary Angioedema (HAE) is a rare genetic disorder that predisposes an individual to develop vasogenic edema. This genetic disorder is caused by the deficiency in functional C1 inhibitor (C1-INH) that results in recurrent attacks of localized subcutaneous or mucosal edema, most commonly affecting the skin, intestines, upper respiratory tract, and oropharynx.
Clinical manifestations include abrupt onset swelling around the eyes, face, and extremities; pain abdomen (because of bowel edema) and laryngeal edema leading to hoarseness of voice, breathing difficulty, and occasionally death.
Hereditary Angioedema (HAE) Diagnosis
Early detection and diagnosis of HAE before the onset of clinical symptoms are critical for appropriate treatment, preserving patients' quality of life, and even the first attack of laryngeal edema can be fatal.
Diagnosis is made through a careful evaluation of clinical symptoms and family history and is confirmed using laboratory testing. Clinical symptoms of recurrent abdominal pain or edema without associated urticaria should prompt suspicion of HAE, particularly in patients with a positive family history.
Continued in the report…..
Hereditary Angioedema (HAE) Epidemiology Perspective by DelveInsight
The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by Diagnosed Prevalent Cases of Hereditary Angioedema (HAE), Type-specific Diagnosed Prevalent Cases of Hereditary Angioedema (HAE), Gender-specific Diagnosed Prevalent Cases of Hereditary Angioedema (HAE), and Age-specific Diagnosed Prevalent Cases of Hereditary Angioedema (HAE) in the 7MM+China covering the United States, the EU4 countries (Germany, France, Italy, Spain) and the United Kingdom, Japan, and China from 2019 to 2032.
Key Findings
- Total diagnosed prevalent cases of HAE in the 7MM+China was found to be 14,375 approximately in 2021, which might increase by the end of 2032. These cases are expected to increase at a considerable CAGR during study period (2019-2032).
- Among 7MM+China, the United States has the highest diagnosed prevalent cases of HAE with 7,614 cases in 2021.
- Among the European countries, the UK had the highest diagnosed prevalent population of HAE, with approximately 1,348 cases, followed by Germany, which had 1,266 diagnosed prevalent population in 2021. On the other hand, Spain and Italy had the lowest and equal number of diagnosed prevalent population as approximately 942 cases in 2021.
- The type-specific diagnosed prevalent cases of HAE is categorized into Type I, Type II, and HAE with normal C1-INH (Type III). Among these, Type I HAE accounted for the highest cases in the 7MM+China as estimated to be 12,345 in 2021.
- The diagnosed prevalent cases of HAE in the 7MM+China varied according to gender, with prevalent cases higher in females than males.
- Based on age segmented as =17 years, 17-65 years, and =65 years, a higher percentage of diagnosed prevalent cases were observed in the age group 17-65 years in all the 7MM+China countries were approximately 11,312 in 2021, which anticipated to rise during the forecasted period (2022-2032).
- Japan accounted for approximately 462 diagnosed prevalent cases of HAE in the year 2021 which are expected to decrease during the forecasted period (2022-2032).
- The total diagnosed prevalent cases of HAE in the China is anticipated to rise from estimated 563 cases in 2021 at a considerable CAGR for the study period (2019-2032).
Scope of the Report:
- The report covers the descriptive overview of HAE, explaining its symptoms, etiology, pathogenesis, and various diagnostic approaches.
- The report provides insight into the 7MM+China historical and forecasted patient pool covering the United States, EU4 countries (Germany, France, Italy, Spain) and the United Kingdom, Japan, and China.
- The report assesses the disease risk and burden of HAE.
- The report helps to recognize the growth opportunities in the 7MM+China with respect to the patient population.
- The report provides the segmentation of the disease epidemiology for 7MM+China diagnosed prevalent cases of Hereditary Angioedema (HAE), type-specific diagnosed prevalent cases of Hereditary Angioedema (HAE), gender-specific diagnosed prevalent cases of Hereditary Angioedema (HAE), and age-specific diagnosed prevalent cases of Hereditary Angioedema (HAE).
Report Highlights:
- 11-Year Forecast of Hereditary Angioedema (HAE)
- The 7MM+China Coverage
- Total diagnosed prevalent cases of Hereditary Angioedema (HAE)
- Type-specific diagnosed prevalent cases of Hereditary Angioedema (HAE)
- Gender-specific diagnosed prevalent cases of Hereditary Angioedema (HAE)
- Age-specific diagnosed prevalent cases of Hereditary Angioedema (HAE)
Key Questions Answered
- What are the disease risk and burdens of Hereditary Angioedema (HAE)?
- What is the historical Hereditary Angioedema (HAE) patient pool in the United States, the EU4 (Germany, France, Italy, Spain) and the UK, Japan, and China?
- What would be the forecasted patient pool of Hereditary Angioedema (HAE) at the 7MM+China level?
- What will be the growth opportunities across the 7MM+China concerning the patient population about Hereditary Angioedema (HAE)?
- Out of the above-mentioned countries, which country would have the highest diagnosed prevalent population of Hereditary Angioedema (HAE) during the forecast period (2022-2032)?
- At what CAGR the population is expected to grow across the 7MM+China during the forecast period (2022-2032)?
Reasons to buy:
The Hereditary Angioedema (HAE) report will allow the user to -
- Develop business strategies by understanding the trends shaping and driving the 7MM+China Hereditary Angioedema (HAE) epidemiology forecast.
- The Hereditary Angioedema (HAE) epidemiology report and model were written and developed by Masters and Ph.D. level epidemiologists.
- The Hereditary Angioedema (HAE) epidemiology model developed by DelveInsight is easy to navigate, interactive with dashboards, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over the 11-year forecast period using reputable sources.
Key Assessments
- Patient Segmentation
- Disease Risk and Burden
- Risk of disease by the segmentation
- Factors driving growth in a specific patient population
Geographies Covered
- The United States
- The EU4 (Germany, France, Italy, Spain) and the United Kingdom
- Japan
- China
Study Period: 2019-2032