PUBLISHER: DelveInsight | PRODUCT CODE: 1226657
PUBLISHER: DelveInsight | PRODUCT CODE: 1226657
"AJM300 Market Drug Insight and Market Forecast - 2032" report provides comprehensive insights about AJM300 for Ulcerative Colitis (UC) in the seven major markets. A detailed picture of the AJM300 for ulcerative colitis in the 7MM, i.e., the United States, EU4 (Germany, France, Italy and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the AJM300 for ulcerative colitis. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the AJM300 market forecast analysis for ulcerative colitis in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in ulcerative colitis.
Carogra (AJM300) is a small molecule compound originated by EA and is the first α4 integrin antagonist drug approved as an orally available dosage form in the world. In UC, lymphocytes and other inflammatory cells excessively aggregate and invade the inflamed site in the colonic mucosa. AJM300 can antagonize both α4B1 and α4B7 integrins expressed on the surface of inflammatory cells and inhibit the cell adhesion mediated by binding to adhesion molecules excessively expressed on the vascular endothelial cells in the colonic mucosa, which suppresses invasion of lymphocytes into the inflamed site to exert anti-inflammation effects.
Dosage
Normally in adults, 960 mg of carotegrast methyl per dose should be taken orally after a meal three times a day.
Mechanism of action
AJM300 is a small molecule that acts on both α4B1 and α4B7 integrins expressed on the surface of inflammatory cells to exert an anti-inflammatory effect by inhibiting the cell adhesion and suppressing excessive aggregation and invasion of inflammatory cells into the inflamed site in the colonic mucosa in UC.
The report provides insights into:
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.
AJM300 Analytical Perspective by DelveInsight
This report provides a detailed market assessment of AJM300 for ulcerative colitis in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2023 to 2032.
The report provides the clinical trials information of AJM300 for ulcerative colitis covering trial interventions, trial conditions, trial status, start and completion dates.
Key Questions