Pulmonary Arterial Hypertension - Epidemiology Forecast to 2030

DelveInsight's 'Pulmonary Arterial Hypertension - Epidemiology Forecast to 2030' report delivers an in-depth understanding of the disease, historical & forecasted epidemiology of Pulmonary Arterial Hypertension in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom) and Japan.

Geography Covered:

• The United States
• EU5 (Germany, France, Italy, Spain and the United Kingdom)
• Japan

Study Period: 2017-2030

Pulmonary Arterial Hypertension Disease Understanding

Pulmonary Arterial Hypertension (PAH) is a rare, chronic, and progressive form of Pulmonary Hypertension which is characterized by the elevated pulmonary arterial pressure (PAP) and pulmonary vascular resistance (PVR) in blood vessels carrying the blood from the right side of the heart through lungs. It occurs due to the tightening and stiffening of the small pulmonary arteries leading to the right ventricular dysfunction and vessel obstruction.

Pulmonary Arterial Hypertension Epidemiology

The Pulmonary Arterial Hypertension epidemiology division provide the insights about historical and current patient pool and forecasted trend for every 7 major countries. The epidemiology data for Pulmonary Arterial Hypertension are studied through all possible division to give a better understanding about the Disease scenario in 7MM. It also helps to recognize the causes of current and forecasted trends by exploring numerous studies, survey reports and views of key opinion leaders.

Pulmonary Arterial Hypertension Epidemiology Segmentation

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology (total prevalent population of PAH, subtype-specific population of PAH and gender-specific PAH diagnosed pool) scenario of Pulmonary Arterial Hypertension in the 7MM covering United States, EU5 countries (Germany, Spain, Italy, France and United Kingdom) and Japan from 2017-2030.

The DelveInsight report also provides the epidemiology trends observed in the 7MM during the study period, along with the assumptions undertaken. The calculated data are presented with relevant tables and graphs to give a clear view of the epidemiology at first sight.

According to DelveInsight, the total number of prevalent cases of Pulmonary Arterial Hypertension in 7MM was found to be 70,774, in the year 2017.

Report Scope:

• The report covers detailed overview of Pulmonary Arterial Hypertension explaining its causes, symptoms, classification, pathophysiology, diagnosis and treatment patterns
• The report provides the insight about the historical and forecasted patient pool of Pulmonary Arterial Hypertension in 7 major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK) and Japan.
• The Report assesses the disease risk and burden and highlights the unmet needs of the disease
• The Report helps to recognize the growth opportunities in the 7MM with respect to the patient population
• The report provides the segmentation of the disease total prevalent population of PAH, subtype-specific population of PAH and gender-specific PAH diagnosed pool in 7MM

Key strengths

• 11 Year Forecast of Pulmonary Arterial Hypertension epidemiology
• 7MM Coverage
• Total Incident Cases of PAHs
• Incident Cases according to segmentation: (total prevalent population of PAH, subtype-specific population of PAH and gender-specific PAH diagnosed pool)

Key assessments

• Patient Segmentation
• Disease Risk & Burden
• Risk of disease by the segmentation
• Factors driving growth in a specific patient population

Table of Contents

1. Key Insights

2. Executive Summary of Pulmonary Arterial Hypertension

3. SWOT Analysis for Pulmonary Arterial Hypertension

4. Pulmonary Arterial Hypertension (PAH) Epidemiology Overview at a Glance

• 4.1. Patient Share (%) Distribution of Pulmonary Arterial Hypertension (PAH) in 2017
• 4.2. Patient Share (%) Distribution of Pulmonary Arterial Hypertension (PAH) in 2030

5. Disease Background and Overview: Pulmonary Arterial Hypertension (PAH)

• 5.1. Introduction
• 5.2. Signs and Symptoms
• 5.3. Classification of Pulmonary Arterial Hypertension (PAH)
  • 5.3.1. WHO classification
  • 5.3.2. Functional Classification of PAH
• 5.4. Etiology
• 5.5. Risk factors
• 5.6. Pathophysiology
• 5.7. Diagnosis
  • 5.7.1. Diagnostic Guidelines: European Guidelines of PAH

6. Epidemiology and Patient Population

• 6.1. Key Findings
• 6.2. Population and Forecast Parameters
• 6.3. 7MM Total Prevalent Patient Population of Pulmonary Arterial Hypertension [PAH]

7. Country Wise-Epidemiology of Pulmonary Arterial Hypertension (PAH)

• 7.1. The United States
  • 7.1.1. Total Prevalent Patient Population of PAH in the United States
  • 7.1.2. Sub-type Specific Prevalence of PAH in the United States
  • 7.1.3. Gender specific Prevalence of PAH in the United States
• 7.2. Germany
  • 7.2.1. Total Prevalent Patient Population of PAH in Germany
  • 7.2.2. Sub-type Specific Prevalence of PAH in Germany
  • 7.2.3. Gender specific Prevalence of PAH in Germany
• 7.3. France
  • 7.3.1. Total Prevalent Patient Population of PAH in France
  • 7.3.2. Sub-type Specific Prevalence of PAH in France
  • 7.3.3. Gender specific Prevalence of PAH in France
• 7.4. Italy
  • 7.4.1. Total Prevalent Patient Population of PAH in Italy
  • 7.4.2. Sub-type Specific Prevalence of PAH in Italy
  • 7.4.3. Gender specific Prevalence of PAH in Italy
• 7.5. Spain
  • 7.5.1. Total Prevalent Patient Population of PAH in Spain
  • 7.5.2. Sub-type Specific Prevalence of PAH in Spain
  • 7.5.3. Gender specific Prevalence of PAH in Spain
• 7.6. The United Kingdom
  • 7.6.1. Total Prevalent Patient Population of PAH in the UK
  • 7.6.2. Sub-type Specific Prevalence of PAH in the UK
  • 7.6.3. Gender specific Prevalence of PAH in the United Kingdom
• 7.7. Japan
  • 7.7.1. Total Prevalent Patient Population of PAH in Japan
  • 7.7.2. Sub-type Specific Prevalence of PAH in Japan
  • 7.7.3. Gender specific Prevalence of PAH in Japan

8. Treatment Algorithm

• 8.1. Current Treatment Practices
• 8.2. Treatment Guidelines
  • 8.2.1. CHEST Guidelines [The United States]
  • 8.2.2. European Society of Cardiology (ESC) and of the European Respiratory Society (ERS) Guidelines

9. Unmet Needs

10. Case Studies

• 10.1. A Rare Case of Drug Induced PAH
• 10.2. A Case Report of Unconventional Delivery of Inhaled NO

11. Organizations related with PAH

12. Appendix

• 12.1. Bibliography
• 12.2. Report Methodology

13. DelveInsight Capabilities

14. Disclaimer

15. About DelveInsight

List of Tables

• Table 1: Summary of Pulmonary Arterial Hypertension (PAH) Epidemiology, and Key Events (2017-2030)
• Table 2: Pulmonary Arterial Hypertension (PAH)
• Table 3: Hemodynamic profiles of pulmonary hypertension
• Table 4: Total Prevalent Patient Population of PAH in 7MM (2017-2030)
• Table 5: Total Prevalent Population of PAH in the United States (2017-2030)
• Table 6: Sub-type Specific Prevalence of PAH in the United States (2017-2030)
• Table 7: Gender specific Prevalence of PAH in the United States (2017-2030)
• Table 8: Total Prevalent Population of PAH in Germany (2017-2030)
• Table 9: Sub-type Specific Prevalence of PAH in Germany (2017-2030)
• Table 10: Gender specific Prevalence of PAH in Germany (2017-2030)
• Table 11: Total Prevalent Population of PAH in France (2017-2030)
• Table 12: Sub-type Specific Prevalence of PAH in France (2017-2030)
• Table 13: Gender specific Prevalence of PAH in France (2017-2030)
• Table 14: Total Prevalent Population of PAH in Italy (2017-2030)
• Table 15: Sub-type Specific Prevalence of PAH in Italy (2017-2030)
• Table 16: Gender specific Prevalence of PAH in Italy (2017-2030)
• Table 17: Total Prevalent Population of PAH in Spain (2017-2030)
• Table 18: Sub-type Specific Prevalence of PAH in Italy (2017-2030)
• Table 19: Gender specific Prevalence of PAH in Spain (2017-2030)
• Table 20: Total Prevalent Population of PAH in the UK (2017-2030)
• Table 21: Sub-type Specific Prevalence of PAH in the UK (2017-2030)
• Table 22: Gender specific Prevalence of PAH in the United Kingdom (2017-2030)
• Table 23: Total Prevalent Population of PAH in Japan (2017-2030)
• Table 24: Sub-type Specific Prevalence of PAH in Japan (2017-2030)
• Table 25: Gender specific Prevalence of PAH in Japan (2017-2030)
• Table 26: Recommendations for efficacy of drug monotherapy for PAH (group 1) according to WHO functional class.
• Table 27: Recommendations for efficacy of initial drug combination therapy for PAH (group 1) according to WHO functional class
• Table 28: Recommendations for efficacy of sequential drug combination therapy for PAH (group 1) according to WHO functional class
• Table 29: Organizations contributing toward Pulmonary Arterial Hypertension

List of Figures

• Figure 1: SWOT Analysis
• Figure 2: Some of the common signs & symptoms of Pulmonary Arterial Hypertension (PAH)
• Figure 3: Classification of Pulmonary Arterial Hypertension (PAH)
• Figure 4: Functional Classification of PAH
• Figure 5: Risk Factors of Pulmonary Arterial Hypertension
• Figure 6: Pathophysiology of Pulmonary Arterial Hypertension (PAH)
• Figure 7: Pathophysiology of Pulmonary Arterial Hypertension (PAH)
• Figure 8: Diagnosis Algorithm of Pulmonary Arterial Hypertension (PAH)
• Figure 9: ESC/ERS Guidelines for the diagnosis of pulmonary hypertension
• Figure 10: Total Prevalent Patient Population of PAH in 7MM (2017-2030)
• Figure 11: Prevalence of PAH in the United States (2017-2030)
• Figure 12: Sub-type Specific Prevalence of PAH in the United States (2017-2030)
• Figure 13: Gender specific Prevalence of PAH in the United States (2017-2030)
• Figure 14: Total Prevalent Population of PAH in Germany (2017-2030)
• Figure 15: Sub-type Specific Prevalence of PAH in Germany (2017-2030)
• Figure 16: Gender specific Prevalence of PAH in Germany (2017-2030)
• Figure 17: Total Prevalent Population of PAH in France (2017-2030)
• Figure 18: Sub-type Specific Prevalence of PAH in France (2017-2030)
• Figure 19: Gender specific Prevalence of PAH in France (2017-2030)
• Figure 20: Total Prevalent Population of PAH in Italy (2017-2030)
• Figure 21: Sub-type Specific Prevalence of PAH in Italy (2017-2030)
• Figure 22: Gender specific Prevalence of PAH in Italy (2017-2030)
• Figure 23: Total Prevalent Population of PAH in Spain (2017-2030)
• Figure 24: Sub-type Specific Prevalence of PAH in Spain (2017-2030)
• Figure 25: Gender specific Prevalence of PAH in Spain (2017-2030)
• Figure 26: Total Prevalent Population of PAH in the UK (2017-2030)
• Figure 27: Sub-type Specific Prevalence of PAH in the UK (2017-2030)
• Figure 28: Gender specific Prevalence of PAH in the United Kingdom (2017-2030)
• Figure 29: Total Prevalent Population of PAH in Japan (2017-2030)
• Figure 30: Sub-type Specific Prevalence of PAH in Japan (2017-2030)
• Figure 31: Gender specific Prevalence of PAH in Japan (2017-2030)
• Figure 32: Treatment Options for Pulmonary Arterial Hypertension (PAH)
• Figure 33: Treatment Algorithm of Pulmonary Arterial Hypertension (PAH)
• Figure 34: Unmet Needs of PAH