PUBLISHER: DataM Intelligence | PRODUCT CODE: 1034823
PUBLISHER: DataM Intelligence | PRODUCT CODE: 1034823
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The magnetic beads market size was valued at US$ XX million in 2020 and is estimated to reach US$ XX million by 2028, growing at a CAGR of XX % during the forecast period (2021-2028).
Magnetic beads are made up of tiny particles of iron oxides, such as magnetite (Fe3O4), which give them superparamagnetic properties. They are widely used for a variety of molecular biology applications, including next-generation sequencing (NGS), polymerase chain reaction (PCR), quantitative PCR (qPCR), droplet digital PCR (ddPCR) and other amplification and genotyping applications.
Increased diagnostic and therapeutic applications and their use in molecular biology are estimated to drive the market.
Increased diagnostic and therapeutic applications are estimated to drive the magnetic beads market
Magnetic beads have a long history of use in diagnostic and therapeutic research. Magnetic nanoparticles are most commonly utilised in the biomedical field as magnetic beads manufactured by embedding magnetic nanoparticles in a suitable matrix, which is usually custom-built to fulfill the needs of individual applications. In most biomedical and life science applications, magnetic nanoparticles come in ferrofluids, which are stable dispersions of magnetic beads in an organic or aqueous carrier medium. However, the physical features of the beads (such as the iron oxide content, which determines their behaviour) must be carefully chosen.
Thermo Fisher Scientific, AMSBIO, IBA, Millipore, Bang Laboratories, BD Sciences, Miltenyi Biotec GmbH, and other firms are leading global magnetic beads providers. Furthermore, numerous smaller companies are developing platforms for cancer diagnostics that separate and count circulating tumour cells. For example, The Sera-Xtracta Virus/Pathogen Kit is a simple and fast way to enhance the process for detecting viruses and other pathogens at low concentrations. The automatable kit with silica-coated magnetic beads can be utilised with various sample types, including respiratory biological matrices, blood, and universal transport media. The kit is developed for high-throughput selective binding of total nucleic acid from bacteria and viruses, including Adenovirus (Type 14), Influenza A (H3N2), and SARS-CoV-2, using non-carrier RNA based chemistry (COVID-19).
Increased use of magnetic beads in molecular biology is estimated to drive the market
In both fundamental research and clinical diagnosis, the use of magnetic beads in molecular biology is rapidly increasing. Superparamagnetic beads, for example, have been demonstrated to be useful in the identification, isolation, and genetic analysis of certain cells, as well as the isolation of nucleic acids, protein purification, and the detection of bacteria and viruses. Thermo Fisher Scientific sells these monosized superparamagnetic particles under the brand name Dynabeads. They are made using a procedure distinct from that used to make other types of magnetic particles, giving them advantages in molecular biology applications. They're also ideal for use in automated applications. Magnetic beads are becoming more popular in life sciences due to their ease of use and elimination of centrifugation processes. Magnetic bead manipulation in lab-on-a-chip systems is also a rapidly emerging field since it allows for manipulation at a distance without disrupting biochemical operations.
MagStrep Type3 XT Beads are coated ferri-magnetic spheres with excellent binding capacity and low non-specific protein binding manufactured by IBA, a biotechnology business. They're used in small-scale purification methods with high protein purity requirements. AMSBIO recently released a line of MagSi magnetic beads with a unique ferrofluid that combines the benefits of small beads and vast surface area with the magnetic performance and strength of bigger beads. These beads are employed in a variety of genomics and proteomics applications.
Disadvantages associated with magnetic beads is estimated to hamper the market
Magnetic beads have become ubiquitous in the life sciences for collecting biological molecules. The beads coated with the appropriate biomarker are incubated with the target suspension in vitro applications. An antigen, protein, antibody, cell or nucleic acid can all be examples of this. The magnetic beads are trapped by a magnetic force, which removes the supernatant from the rest of the sample. If necessary, the clean buffer can be added to resuspension the purified molecule. Biomagnetic separation is becoming more industrialised, which necessitates better protocols, validation methodologies, and quality controls for all operations. Many protocols are suitable for R&D labs with small volumes and manual operation.
Commercial robotic analyzers and large-volume IVD production lines, on the other hand demand more stringent standards. Automated analyzers require a well-controlled and repeatable separation time for each test even with small volumes. In order to meet the demand generated by the robotic analyzers the production lines must be able to handle enormous volumes. Nonetheless, to minimize the end-product variability they also require a high degree of in-lot and lot-to-lot consistency.The bead's magnetic moment can be determined by the magnitude of the magnetic field. When the field is small, and the beads are far from the retention area, their susceptibility is constant, and their magnetic moment varies linearly with the applied field. The magnetic field around the retention area can be strong enough to saturate the magnetic moment, causing the beads to behave as miniature permanent magnets. One can't specify a single magnetic force value under these circumstances. As a result, the majority of magnetic separation techniques are often defined solely by separation duration.
COVID-19 has affected many industries. To stop its development, government-imposed lockdown. People are scared they will experience negative health and occupational effects from the COVID-19 pandemic. All the manufacturing, as well as supply chains, have been hit due to the COVID-19 restrictions. Hence, the magnetic beads market has seen a decrease in its market.
Ferrimagnetic segment is estimated to dominate the magnetic beads market
Ferrimagnetism is a type of permanent magnetism that occurs in solids when the magnetic fields associated with individual atoms spontaneously align, some parallel or in the same direction (as in ferromagnetism), and others antiparallel or in opposite directions (as in antiferromagnetism). The parallel alignment is responsible for the magnetic behaviour of single crystals of ferrimagnetic materials; the diluting effect of atoms in the antiparallel arrangement keeps the magnetic strength of these materials lower than that of purely ferromagnetic solids like metallic iron.
In a wide range of applications ferromagnetic materials are used such as actuators, sensors, transformers or motors. The main property of interest is their capability to reach high magnetization levels when subjected to magnetic field of relatively low intensity and external magnetic field. This property originates in the complex magnetic domain microstructure and its evolution under the application of external loading. In that sense, magnetic behaviour is a good example of multiscale phenomena and a natural playground for multiscale modelling approaches. Hence, its wide application is estimated to dominate the market.
Biomolecules separation and purification application segment is estimated to dominate the market
Cell biologists research the relationship between structure and function at the molecular, subcellular, and cellular levels.While a complex biological system such as a biochemical pathway can only be understood after each one of its components has been analysed separately. Only if a cellular or biomolecule component is pure and biologically still active can it be characterised and its biological functions elucidated. In comparison with standard separation procedures magnetic separation techniques have several advantages. This process is very simple usually with only a few steps. All the purification procedure steps can take place in one single test tube or another vessel. There is no need for centrifuges, expensive liquid chromatography systems,filters or other equipment. The separation process can be performed directly in crude samples containing suspended solid material.
In some cases (e.g., isolation of intracellular proteins), it is even possible to integrate the disintegration and separation steps, thus shortening the total separation time. Magnetic beads are versatile little tools for the effective and easy isolation of biomolecules. A key advantage of using magnetic beads is that one can isolate nucleic acids and other biomolecules directly from a crude sample and from various types of samples, with minimal processing. This sets magnetic beads apart from other nucleic acid isolation methods, which might have different protocols for different samples and involve more hands-on time.
North America region is estimated to dominate the magnetic beads market
Due to high research facilities, funding for research, and major key players, this region is estimated to dominate the magnetic beads market.
In the United States there are 261 research universities. And North America region has more involvement in the manufacturing of magnetic beads. For example, Thermo Fisher Scientific, an American provisioner of scientific instrumentation, reagents and consumables, and software services manufactuers dynabeads product that centre around the goals to provide the highest quality products consistently for precious samples.Across multiple application areas these deliver the most cited results in the industry.
Major key players present in the magnetic beads market are Thermo Fisher Scientific Inc., Advanced BioChemicals (ABC), Promega Corporation, Zeesan Biotech Co. Ltd., New England BioLabs Inc., Calbiotech, MagBio Genomics, Teja Scientific Glass Works, Vazyme Biotech Co. Ltd., and Alcon Scientific Industries.
Magnetic Beads Market Key Companies to Watch
Thermo Fisher Scientific Inc
Overview: Thermo Fisher Scientific Inc. is the world leader in serving science. The company's aim is to make the world a better, cleaner, and safer place for its clients. The company assists its customers in accelerating life sciences research, improve patient diagnostics, overcome complex analytical challenges, bring drugs to market, and increase laboratory productivity. The company offers an unequalled combination of breakthrough technologies, purchasing convenience, and complete services through their renowned brands Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, and Unity Lab Services.
Product Portfolio: The company comprises analytical instruments, laboratory supply chain programs and e-commerce, laboratory equipment, lab services, specialty diagnostics, life sciences, pharma services, and CDMO.
Key Development: Thermo Fisher Scientific (TFS) has announced a definitive agreement to acquire clinical research organisation PPD. On concluding the acquisition, PPD will become part of the Thermo Fisher's Laboratory Products and Services segment.
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Global Magnetic Beads Market - By Magnetic core
Global Magnetic Beads Market - By Application
Biomolecules separation & purification
Molecular & immunodiagnostics
Global Magnetic Beads Market - By Region
Middle East and Africa