Global Surgical Glue Market - 2022-2029

Market Overview

Surgical Glue Market size was valued US$ 5.28 billion in 2021 and is estimated to reach US$ 9.13 billion by 2029, growing at a CAGR of 7.64% during the forecast period (2022-2029).

Surgical glues (also called surgical sealants or adhesives) are used after a surgery or traumatic injury to bind together external or internal tissue. Surgical glues can be used in conjunction with or as an alternative to sutures and staples; they use a chemical bond to hold tissue together for healing or serve as a barrier to stop bodily fluids flow. Advancements in the surgical glue market were primarily aimed at addressing the limitations of traditional wound sealing techniques. Furthermore, due to surgical glue's favorable biological and physical properties, more surgeons are using this technique to seal wounds. Surgical glue is derived from several natural biopolymers, including gelatin, collagen, chitosan, albumin, and fibrin.

Market Dynamics

The market growth is driven by various factors such as rise in the number of surgical procedures and burn cases and increasing incidences of road accidents globally and rising health awareness.

Increasing number of surgical procedures and rising traumatic injuries are expected to drive market growth.

The rising number of traumatic injuries drives the market. The market growth is also majorly driven by the rise in the number of surgical procedures and burn cases and increasing incidences of road accidents globally. The rising health awareness and high prevalence of diseases (such as skin diseases, cancer, heart diseases, and respiratory diseases) have increased the opportunities for surgeries.

According to the World Health Organization (WHO) 2020 report, estimates approximately 1.35 million people die each year due to road traffic crashes. 20 to 50 million people suffer from non-fatal injuries, with many incurring a disability resulting from their injury. 93% of the world's fatalities on the roads occur in low and middle-income countries, even though they have approximately 60% of the world's vehicles. Even within high-income countries, individuals from lower socioeconomic backgrounds are more likely to be involved in road traffic crashes. Thus, the rising prevalence of diseases along with road injury cases is expected to drive the market.

Additionally, there are innumerable accessibility and availability of these devices across the globe, which is one of the major reasons for the growth of the surgical glue market. It has been observed that the citizens of both developed and developing countries are extensively spending on healthcare services due to the increasing disposable income of the residents of those countries and increasing health issues.

According to a recent study published by the Centers for Disease Control and Prevention (CDC), it has been established that the total expenditure on healthcare services in the U.S. has projected towards a total of $3.9 trillion. Moreover, according to a report furnished by the U.K. Office for National Statistics (ONS), the U.K.'s total healthcare expenditure accounted for approximately $300 billion in the recent past.

The abovementioned data indicate that countries are increasingly spending on healthcare and related facilities owing to rising medical awareness, growth in disposable income, and various developments in surgical facilities. Thus, patients suffering from various diseases are going for surgeries (better and quick treatment options), which drives the global surgical glue market growth.

Side effects associated with surgical glue and legal complexities expected to hamper the growth of market

Surgical glue has several limitations associated with its usability and safety, such as allergic reactions, wound dehiscence, and skin infections. Besides, it is categorized as class II by the FDA and class B by the Drugs and Cosmetics Acts (1940) in India, making it a little risky and thus requiring clinical trials and further leading to legal complexities. The safety, quality, and performance of these materials are necessary facets requiring stringent evaluation for public health, which lead to complex and strict regulations for their affiliation. Therefore, these factors are hampering the growth of the surgical glue market.

Industry Analysis

The global surgical glue market provides in-depth analysis of the market based on various industry factors such as porter's five forces, regulatory analysis, supply chain analysis and pricing analysis.

Segment Analysis

Cyanoacrylates segment is expected to hold the largest market share in global surgical glue market

The global surgical glue market is segmented on fibrin, collagen, gelatin, cyanoacrylate, polymeric hydrogel, and urethane-based adhesive. The cyanoacrylates segment held the largest market share. Cyanoacrylate is a sticky substance found in many types of glue. Cyanoacrylate poisoning occurs when someone swallows this substance or gets it on their skin. Once the applicator is initiated and the cyanoacrylate adhesive is applied to moist tissue, the polymerization process occurs. A feature of our cyanoacrylate devices is that only a low heat level is generated when this polymerization starts. Consequently, the patient does not experience the stinging or burning sensation that occurs with some competitor products.

Cyanoacrylate glue is biocompatible and does not need removal as it naturally slough off the skin as part of the natural wound healing process. Cyanoacrylate properties, namely fast-setting, high tensile strength polymers that bind with the skin's surface and are flexible, durable, waterproof, and transparent on the setting, make cyanoacrylate ideal for wound closure and skin barrier products. Cyanoacrylates provide a non-traumatic means of wound closure and enhance the patient experience over conventional wound closure methods. They are commonly used to close laparoscopic incisions and are much stronger than fibrin sealants and sutures. Cyanoacrylates are waterproof, flexible, and require no dressing on the wound.

The fibrin glue segment is expected to have positive market growth in the forecast period. Fibrin glue is a type of surgical adhesive derived from both human and animal (bovine) blood products. Ingredients in the fibrin sealant interact during application to form a clot made from fibrin's blood protein. Fibrin sealants are effective for cardiovascular surgery, lung surgery, and closure of the Dural (a fibrous membrane covering the brain and spinal cord) and can be used to close spleen and liver lacerations.

Fibrin sealant is also used in hemostasis processes to control bleeding during and after surgical procedures, one of the leading fibrin sealants market trends. Fibrin sealant comprises fibrinogen and thrombin, which play a vital role in the hemostasis process during severe bleeding. . Fibrin sealant is the only commercially available FDA-approved material for clinical use a hemostat sealant and adhesive. Fibrin sealants are referred to as the most adopted hemostats worldwide.

Further, the market is also classified based on cardiovascular surgery, orthopedic surgery, general surgery, cosmetic surgery, pulmonary surgery, central nervous system surgery, and others. The cardiovascular surgery segment is held the largest market share. The rise in the incidence of diseases correspondingly drives the number of surgical procedures performed, thereby boosting surgical glues in surgeries and, mainly, cardiovascular procedures globally. It has been a standard procedure in most medical centers providing surgical services for several years. Both the range and the number of surgical procedures performed are constantly increasing, driving the segment.

The globally increasing aging population is one of the major drivers of this segment. According to WHO, the world's geriatric population is expected to nearly double from 12.0% to 22.0% between 2015 and 2050. The market is expected to be driven by a vascular malfunction in the geriatric population and a rise in congenital disabilities. Furthermore, physical inactivity and an unhealthy lifestyle are also increasing the incidence of cardiovascular conditions.

According to the American Heart Association Research, cardiovascular diseases accounted for more than 8 lakh deaths in the U.S. in 2016. It has been observed that these diseases claim more lives than chronic lower respiratory disease and cancer combined. Approximately 2,300 Americans die due to cardiovascular diseases each day, an average of one death every 38 seconds. This factor will drive the growth of the segment.

The cosmetic surgery segment is expected to have positive market growth in the forecast period. This is due to the increasing adoption of surgical glue for cosmetic procedures and burns treatment surgeries. It is further set to increase with the increasing number of facial cosmetic surgeries, increasing cases of skin injuries, growing incidence of burn injuries, and an increasing number of breast cancer patients undergoing mastectomy and breast reconstruction procedures across the globe. This factor will drive the growth of the market in the forecast period.

Geographical Analysis

North America region holds the largest market share in the global surgical glue market

By region, the global surgical glue market is segmented into North America, South America, Europe, Asia-Pacific, Middle-East, and Africa. Among all of the regions, North America dominated the global surgical glue market and is expected to grow at the highest CAGR during the forecast period. North America is anticipated to continue being the largest-growing surgical glue market in the coming years. The factors contributing to the growth include the increasing investments in R&D of medical adhesives and their several applications in different surgeries performed in the region. As per Heart Disease & Stroke Statistical Fact Sheet 2020, estimates that a minimum of 40,000 infants is expected to be affected each year by congenital heart defects in the United States. Of these, about 25%, or 2.4 (per 1,000 live births), require treatment in the first year of life. Moreover, the increasing demand for and focus on cosmetic surgery and its growing awareness of preventative and corrective treatment in the USA are driving the growth of the market in this region.

The Asia-Pacific region is expected to have the third-largest share due to a large patient pool, availability of skilled technicians at a comparatively lower price, and a defined regulatory framework favoring expedited product approvals. Furthermore, the booming medical tourism industry in India, China, and Malaysia is expected to boost demand for surgical glue.

Competitive Landscape

The global surgical glue market is highly competitive with the presence of several international and local markets. Product diversification, revenue generation, and opportunities intensify the market competition B. Braun Melsungen AG, Baxter International Inc., Advanced Medical Solutions Group PLC, C. R. Bard Inc., Cardinal Health Inc., CryoLife Inc., Integra Lifesciences Holdings Corporation, Cohera Medical Inc., Takeda Pharmaceutical Company Limited., and Johnson & Johnson, Medtronic PLC. are the leading market players with significant market share. The major players are using product development, novel product launches, market expansion, and product diversification strategies for holding their position in the market.

The companies enter into collaborations, mergers, strategic partnerships, and acquisitions to expand their presence and meet the rising demand for surgical glue across the globe. For instance,

• In Jul 2021, Baxter acquired PerClot polysaccharide hemostatic system to increase its advanced surgery portfolio with active and passive hemostatic solutions.
• In June 2019, the research team at Technion - Israel Institute of Technology announced that they had developed a new surgical glue that is non-toxic, biodegradable, and flexible. The new product is compatible with both internal as well as external surgeries. Despite emerging as a reliable alternative for surgical staplers and sutures, surgical glue is typically used only for external applications.

Key Companies to Watch

B. Braun Melsungen AG:

Overview: B. Braun is German company that manufactures medical and pharmaceuticals device. Headquartered in Melsungen, Germany and founded in 1839. They provide services in around 60 countries that employees around 63,000 people. They have aroubd 5,000 variety of healthcare products.

Product Portfolio:

Histoacryl: It is a tissue adhesive which contains monomeric n-butyl-2-cyanoacrylate, that quickly polymerises in connection to tissue fluid. It can be found in two colours: translucent, that is specially designed for facial application and blue, that provides easy control over the amount applied.

Key Developments: In Jun 2020, B. Braun announced about extending its portfolio of healthcare solutions testing capabilities.

The global surgical glue market report would provide an access to an approx. 45+market data table, 40+figures and 180pages.