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PUBLISHER: DelveInsight | PRODUCT CODE: 1147335

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PUBLISHER: DelveInsight | PRODUCT CODE: 1147335

Eosinophilic Esophagitis - Market Insight, Epidemiology And Market Forecast - 2032

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DelveInsight's 'Eosinophilic Esophagitis (EoE) - Market Insights, Epidemiology, and Market Forecast - 2032' report delivers an in-depth understanding of the historical and forecasted epidemiology as well as the market trends of EoE in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.

The eosinophilic esophagitis (EoE) market report provides current treatment practices, emerging drugs, market share of the individual therapies, and current and forecasted eosinophilic esophagitis (EoE) market size from 2019 to 2032, segmented by 7MM. The report also covers the current eosinophilic esophagitis (EoE) treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying market potential.

Geographies Covered:

  • The United States
  • EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan

Study period: 2019-2032.

Eosinophilic Esophagitis (EoE): Disease Understanding and Treatment Algorithm

Eosinophilic Esophagitis (EoE) Overview

According to the National Organization for Rare Disorders (NORD) and the American Academy of Allergy, Asthma, and Immunology (AAAAI), eosinophilic esophagitis (EoE), also known as "asthma of the esophagus," is defined as a chronic, local immune-mediated disorder of the digestive system in which large numbers of a particular type of white blood cell called eosinophils are present in the esophagus, clinically and histologically characterized by symptoms related to esophageal dysfunction and eosinophil-predominant inflammation. The major symptoms include heartburn, regurgitation, esophageal stenosis, and dysphagia, which are more frequent in young adults and children.

The diagnosis of EoE depends on the clinical manifestations and endoscopic and histological findings in esophageal mucosa biopsies. Endoscopic findings in most patients include linear grooves on the esophagus wall, concentric rings, whitish exudates that resemble candidal infection, Schatzki rings, a reduction in the size of the esophagus, and superficial tears of the mucosa after endoscope introduction. A histological diagnosis is confirmed when there are ≥15 eosinophils per high-power field (HPF).

The main aim of the treatment of EoE is not only clinical improvement but also histological improvement to prevent the development of esophageal stricture. In 2020, the American Gastroenterology Association (AGA) and the Joint Task Force on Allergy-Immunology Practice Parameters (JTF) recommended certain guidelines on the management of EoE. The therapeutic approach against EoE consists of the "3D" concept: Diet, drugs, and dilation. The patient is treated based on the severity of their symptoms or endoscopic findings, such as esophageal narrowing or stricture. Histological improvement is generally used as the primary outcome in clinical trials rather than symptomatic improvement due to the difficulty in evaluating the symptoms objectively and uniformly. It is common for these patients to modify their diet or eating behavior to avoid dysphagia or an impaction. PPIs are useful as a first-line treatment for patients with EoE. Corticosteroids are another effective therapy for the treatment of EoE. The formulation of the most commonly used corticosteroids, including budesonide, fluticasone propionate, and ciclesonide, influences histological remission. IL-4 and IL-13 inhibitors are promising in clinical trials, and recently the Food and Drug Administration (FDA) approved DUPIXENT (dupilumab) to treat EoE in adults and pediatric patients aged 12 and older weighing at least 40 kg (which is about 88 pounds), as the first treatment for EoE. Esophageal endoscopic dilation is most commonly used in adults with established esophageal strictures. According to recent EoE consensus statements and societal guidelines, periodic dilation is considered an acceptable alternative to medical or dietary therapy in some healthy adults with EoE.

Eosinophilic Esophagitis (EoE) Diagnosis and Treatment

It covers the details of conventional and current medical therapies and diagnoses available in the eosinophilic esophagitis (EoE) market to treat the condition. It also provides country-wise treatment guidelines and algorithms across the United States, Europe, and Japan.

Eosinophilic Esophagitis (EoE) Epidemiology

The eosinophilic esophagitis (EoE) epidemiology division provides insights into the historical and current patient pool and the forecasted trend for every 7MM. It helps recognize the causes of current and forecasted trends by exploring numerous studies and views of KOL. The report also provides the prevalent patient pool, trends, and assumptions.

Key Findings

The disease epidemiology covered in the report provides historical and forecasted eosinophilic esophagitis (EoE) epidemiology segmented as the diagnosed prevalent cases of eosinophilic esophagitis (EoE), age-specific cases of eosinophilic esophagitis (EoE), and gender-specific cases of eosinophilic esophagitis (EoE). The report includes the diagnosed prevalent eosinophilic esophagitis (EoE) scenario in the 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom), and Japan from 2019 to 2032.

Country-wise Eosinophilic Esophagitis (EoE) Epidemiology

The epidemiology segment also provides the eosinophilic esophagitis (EoE) epidemiology data and findings across the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.

The total diagnosed prevalent patient population of eosinophilic esophagitis (EoE) in the 7MM countries was more than 700,000 cases in 2021.

As per the estimates, the US had the highest patient population of eosinophilic esophagitis (EoE) in 2021. Among the EU5 countries, Germany had the highest diagnosed patient population of eosinophilic esophagitis (EoE), with approximately 58,000 cases, followed by France in 2021. On the other hand, Spain had the lowest diagnosed prevalent patient population of eosinophilic esophagitis (EoE), with nearly 33,000 cases in 2021.

Eosinophilic Esophagitis (EoE) Drug Chapters

The drug chapter segment of the eosinophilic esophagitis (EoE) report encloses the detailed analysis of eosinophilic esophagitis (EoE) marketed drugs and late-stage (Phase III, Phase II/III, and Phase II) pipeline drugs. It also helps understand the eosinophilic esophagitis (EoE) clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug, and the latest news and press releases.

The current standard of care with swallowed corticosteroid are related to well-known adverse effects (especially in the pediatric population) and there is not enough long-term data to confirm that they can reverse the remodeling process of the esophageal mucosa. Additionally, the topical treatment in the upper gastrointestinal tract is tremendously difficult due to ultra-short esophageal transit times of less than 2 s from the mouth to the stomach. A few clinical studies have systematically evaluated the use of monoclonal antibodies in EoE.

Thus, there is an urgent need to identify new and existing medications that are potentially safe and effective for EoE patients and evaluate those therapies using appropriate clinical trials.

Products detail in the report…

Eosinophilic Esophagitis (EoE) Emerging Drugs

Drug developers are gradually shifting their attention toward eosinophilic esophagitis (EoE) to meet the patient pool's current demands and counter the unmet needs of the therapeutic market.

Several companies are working robustly on many new therapies, such as cendakimab (BMS), benralizumab (AstraZeneca), estrasimod (Pfizer), ESO-101 (ESOCAP), lirentelimab (Allakos), APT-1011 (Ellodi Pharmaceutical).

Cendakimab/RPC4046/CC-93538 (BMS) is a recombinant humanized, high affinity, selective, anti-IL-13 mAb. RPC4046 binds an IL-13 epitope that prevents its binding to both IL-13R (alpha) 1 and IL-13R (alpha) 2, providing potential efficacy and/or safety advantages. The drug has been granted ODD for the treatment of EoE by the US FDA. In the Phase II study, RPC4046 demonstrated positive results, and currently, the company is conducting two Phase III clinical studies to evaluate the efficacy and safety of CC-93538 in adult and adolescent participants with EoE.

APT-1011 (Ellodi Pharmaceutical), a novel, oral formulation of fluticasone incorporating Adare's proprietary AdvaTab technology, allows for topical delivery of the drug to the esophagus whilst minimizing residence time in the oral cavity. In earlier clinical trials, APT-1011 effectively reduced esophageal eosinophil counts and endoscopic findings in adults with a diagnosis of EoE. APT-1011 has received ODD from the FDA and EMA and FDT from FDA. It is currently in Phase III development (FLUTE II), following the successful completion of its Phase II study (FLUTE I) in 2019.

Products detail in the report…

Eosinophilic Esophagitis (EoE) Market Outlook

The eosinophilic esophagitis (EoE) market outlook of the report builds a detailed comprehension of the historical, current, and forecasted eosinophilic esophagitis (EoE) market trends by analyzing the impact of current therapies on the market, unmet needs, and demand for better technology.

This segment gives a thorough detail of the eosinophilic esophagitis (EoE) market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need for the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market, and KOL view. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

As per DelveInsight, the eosinophilic esophagitis (EoE) market in 7MM is expected to change in 2019-2032.

Key Findings

This section includes a glimpse of the eosinophilic esophagitis (EoE) market in 7MM. In the 7MM, the eosinophilic esophagitis (EoE) market size was approximately USD 600 million in 2021.

The United States: Market Outlook

This section provides the total eosinophilic esophagitis (EoE) market size. It also provides the market size of eosinophilic esophagitis (EoE) by therapies in the United States.

The United States accounts for the highest market size of eosinophilic esophagitis (EoE) than the EU5 (the United Kingdom, Germany, Italy, France, and Spain) and Japan.

EU5 Countries: Market Outlook

This section provides the total eosinophilic esophagitis (EoE) market size. It also provides eosinophilic esophagitis (EoE) market size by therapies in Germany, France, Italy, Spain, and the United Kingdom.

Japan Market Outlook

This section provides the total eosinophilic esophagitis (EoE) market size. It also provides the market size of eosinophilic esophagitis (EoE) by therapies in Japan.

Eosinophilic Esophagitis (EoE) Drugs Uptake

This section focuses on the uptake rate of potential drugs launched or expected to be launched in the market during 2019-2032. The analysis covers eosinophilic esophagitis (EoE) market uptake by drugs, patient uptake by therapies, and sales of each drug.

This helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on market share and size, which again will be useful in investigating factors important in the market uptake and making financial and regulatory decisions.

Eosinophilic Esophagitis (EoE) Pipeline Development Activities

The report provides insights into different therapeutic candidates in Phase III, Phase II/III, Phase II, and Phase I/II. It also analyses eosinophilic esophagitis (EoE)'s key players in developing targeted therapeutics.

Major players include: Bristol Myers Squibb, Ellodi Pharmaceuticals, and AstraZeneca whose key products are expected to get launched in the US market by 20XX.

Pipeline Development Activities

The report covers collaborations, acquisitions, mergers, licensing, and patent details for emerging eosinophilic esophagitis (EoE) therapies.

KOL Views

To keep up with current market trends, we take KOLs and SMEs' opinions working in the eosinophilic esophagitis (EoE) domain through primary research to fill the data gaps and validate our secondary research. Their opinion helps understand and validate current and emerging treatment patterns or eosinophilic esophagitis (EoE) market trends. This will support the clients in potential novel treatments by identifying the overall scenario of the market and the unmet needs.

Competitive Intelligence Analysis

We perform a competitive and market intelligence analysis of the eosinophilic esophagitis (EoE) market using various competitive intelligence tools: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies, etc. The inclusion of the analysis entirely depends upon the data availability.

Scope of the Report:

  • The report covers the descriptive overview of eosinophilic esophagitis (EoE), explaining its causes, signs and symptoms, pathophysiology, and currently available therapies
  • Comprehensive insight is provided into the eosinophilic esophagitis (EoE) epidemiology and treatment in the 7MM
  • Additionally, an all-inclusive account of both the current and emerging therapies for eosinophilic esophagitis (EoE) is provided, along with the assessment of new therapies that will impact the current treatment landscape
  • A detailed review of the eosinophilic esophagitis (EoE) market; historical and forecasted, is included in the report, covering drug outreach in the 7MM
  • The report provides an edge while developing business strategies by understanding trends shaping and driving the global eosinophilic esophagitis (EoE) market

Report Highlights:

  • Recently, the eosinophilic esophagitis (EoE) market is set to change due to the rising awareness of the disease and incremental healthcare spending worldwide; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market
  • The companies and academics are working to assess challenges and seek opportunities that could influence eosinophilic esophagitis (EoE) R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition
  • Major players are involved in developing therapies for eosinophilic esophagitis (EoE). The launch of emerging therapies will significantly impact the eosinophilic esophagitis (EoE) market
  • For eosinophilic esophagitis (EoE), a better understanding of disease pathogenesis will also contribute to developing novel therapeutics
  • Our in-depth analysis of the pipeline assets across different stages of development (Phase III and Phase II), different emerging trends, and comparative analysis of pipeline products with detailed clinical profiles, key cross-competitor, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the R&D activities

Eosinophilic Esophagitis (EoE) Report Insights

  • Patient Population
  • Therapeutic Approaches
  • Eosinophilic Esophagitis (EoE) Pipeline Analysis
  • Eosinophilic Esophagitis (EoE) Market Size and Trends
  • Market Opportunities
  • Impact of upcoming Therapies

Eosinophilic Esophagitis (EoE) Report Key Strengths

  • 11-year Forecast
  • 7MM Coverage
  • Eosinophilic Esophagitis (EoE) Epidemiology Segmentation
  • Key Competitors
  • Highly Analyzed Market
  • Drugs Uptake

Eosinophilic Esophagitis (EoE) Report Assessment

  • Current Treatment Practices
  • Unmet Needs
  • Pipeline Product Profiles
  • Market Attractiveness

Key Questions

Market Insights:

  • What was the market share percentage distribution, and how would it look by 2032?
  • What would be the total market size and market size of eosinophilic esophagitis (EoE) by therapies across the 7MM forecast period (2019-2032)?
  • What are the key findings about the market across 7MM, and which country will have the largest eosinophilic esophagitis (EoE) market size during the forecast period (2019-2032)?
  • At what CAGR is the eosinophilic esophagitis (EoE) market expected to grow in the 7MM forecast period (2019-2032)?
  • What would be the eosinophilic esophagitis (EoE) market outlook across the 7MM forecast period (2019-2032)?
  • What would be the eosinophilic esophagitis (EoE) market growth until 2032 and the resultant market size by 2032?
  • How would future opportunities affect the market dynamics and subsequent analysis of the associated trends?

Epidemiology Insights:

  • What are the disease risk, burdens, and unmet needs of eosinophilic esophagitis (EoE)?
  • What is the historical patient pool of eosinophilic esophagitis (EoE) covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan?
  • What would be the forecasted patient pool of eosinophilic esophagitis (EoE) covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan?
  • What will be the growth opportunities in the 7MM concerning the patient population of eosinophilic esophagitis (EoE)?
  • Out of all the 7MM, which country would have the highest prevalence of eosinophilic esophagitis (EoE) during the forecast period (2019-2032)?
  • At what CAGR is the population expected to grow in the 7MM forecast period (2019-2032)?

Current Treatment Scenario, Marketed Drugs, and Emerging Therapies:

  • What are the current options to treat eosinophilic esophagitis (EoE)?
  • What are the current treatment guidelines for treating eosinophilic esophagitis (EoE) in the US, Europe, and Japan?
  • What are the eosinophilic esophagitis (EoE) marketed drugs and their MOA, regulatory milestones, product development activities, advantages, disadvantages, safety, efficacy, etc.?
  • How many companies are developing therapies to treat eosinophilic esophagitis (EoE)?
  • How many therapies are developed by each company to treat eosinophilic esophagitis (EoE)?
  • How many emerging therapies are in the mid-stage and late stages of development to treat eosinophilic esophagitis (EoE)?
  • What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, and licensing activities related to eosinophilic esophagitis (EoE) therapies?
  • What are the recent novel therapies, targets, mechanisms of action, and technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies for eosinophilic esophagitis (EoE) and its status?
  • Which key designations have been granted for the emerging therapies for eosinophilic esophagitis (EoE)?
  • What are the global historical and forecasted eosinophilic esophagitis (EoE) markets?

Reasons to buy:

  • The report will help in developing business strategies by understanding trends shaping and driving the eosinophilic esophagitis (EoE) market
  • To understand the future market competition in the eosinophilic esophagitis (EoE) market and an insightful review of the key market drivers and barriers
  • Organize sales and marketing efforts by identifying the best opportunities for eosinophilic esophagitis (EoE) in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom), and Japan
  • Identifying upcoming solid players in the market will help devise strategies that will help get ahead of competitors
  • Organize sales and marketing efforts by identifying the best opportunities for the eosinophilic esophagitis (EoE) market
  • To understand the future market competition in the eosinophilic esophagitis (EoE) market
Product Code: DIMI0410

Table of Contents

1. Key Insights

2. Report Introduction

3. Eosinophilic Esophagitis (EoE) Market Overview at a Glance

  • 3.1. Market Share (%) Distribution of Eosinophilic Esophagitis (EoE) in 2019
  • 3.2. Market Share (%) Distribution of Eosinophilic Esophagitis (EoE) in 2032

4. Executive Summary of Eosinophilic Esophagitis

5. Disease Background and Overview

  • 5.1. Introduction
  • 5.2. Clinical Manifestation
  • 5.3. Risk Factors
    • 5.3.1. Phenotypes, endotypes, and genotype correlation in EoE
  • 5.4. Pathophysiology
  • 5.5. Diagnosis
    • 5.5.1. Biomarkers
    • 5.5.2. Differential diagnosis
    • 5.5.3. Complexities in EoE diagnosis
  • 5.6. Treatment
    • 5.6.1. Treatment Guidelines
      • 5.6.1.1. AGA Institute and the Joint Task Force on Allergy-Immunology Practice Parameters Clinical Guidelines for the Management of EoE
      • 5.6.1.2. European Statements and Recommendations on the Management of EoE

6. Epidemiology and Patient Population

  • 6.1. Key Findings
  • 6.2. Total Diagnosed Prevalence of EoE in the 7MM
  • 6.3. Assumptions and Rationale
  • 6.4. The United States
    • 6.4.1. Total Diagnosed Prevalence of EoE in the United States
    • 6.4.2. Age-specific Cases of EoE in the United States
    • 6.4.3. Gender-specific Cases of EoE in the United States
  • 6.5. The EU5
    • 6.5.1. Total Diagnosed Prevalent Cases of EoE in the EU5
    • 6.5.2. Age-specific cases of EoE in the EU5
    • 6.5.3. Gender-specific cases of EoE in the EU5
  • 6.6. Japan
    • 6.6.1. Total Diagnosed Prevalent Cases of EoE in Japan
    • 6.6.2. Age-specific cases of EoE in Japan
    • 6.6.3. Gender-specific cases of EoE in Japan

7. Patient Journey

8. Marketed Therapies

  • 8.1. Key Cross: Marketed Products
  • 8.2. JORVEZA (budesonide): Dr. Falk Pharma GmbH
    • 8.2.1. Drug description
    • 8.2.2. Regulatory milestone
    • 8.2.3. Other development activities
    • 8.2.4. Safety and efficacy
    • 8.2.5. Side effects
    • 8.2.6. Product profile
  • 8.3. DUPIXENT: Regeneron Pharmaceuticals/Sanofi
    • 8.3.1. Drug description
    • 8.3.2. Regulatory milestone
    • 8.3.3. Other development activities
    • 8.3.4. Safety and efficacy
    • 8.3.5. Side effects
    • 8.3.6. Product profile

9. Emerging Therapies

  • 9.1. Key Cross: Emerging Therapies
  • 9.2. Cendakimab: Bristol Myers Squibb (BMS)
    • 9.2.1. Drug description
    • 9.2.2. Other development activities
    • 9.2.3. Clinical development
      • 9.2.3.1. Clinical trial information
    • 9.2.4. Safety and efficacy
    • 9.2.5. Product profile
    • 9.2.6. Analyst comments
  • 9.3. APT-1011: Ellodi Pharmaceuticals
    • 9.3.1. Drug description
    • 9.3.2. Other development activities
    • 9.3.3. Clinical development
      • 9.3.3.1. Clinical trial information
    • 9.3.4. Safety and efficacy
    • 9.3.5. Product profile
    • 9.3.6. Analyst comment
  • 9.4. FASNERA (Benralizumab): AstraZeneca/Kyowa Hakko Kirin
    • 9.4.1. Drug description
    • 9.4.2. Other development activities
    • 9.4.3. Clinical development
      • 9.4.3.1. Clinical trial information
    • 9.4.4. Product profile
    • 9.4.5. Analyst comment

10. Other Assets

  • 10.1. Key Cross: other assets
  • 10.2. Lirentelimab: Allakos
    • 10.2.1. Drug description
    • 10.2.2. Other development activities
    • 10.2.3. Clinical development
      • 10.2.3.1. Clinical trial information
    • 10.2.4. Safety and efficacy
    • 10.2.5. Product profile
  • 10.3. Etrasimod: Pfizer
    • 10.3.1. Drug description
    • 10.3.2. Other development activities
    • 10.3.3. Clinical development
    • 10.3.4. Clinical trial information
    • 10.3.5. Product profile
  • 10.4. IRL201104: Revolo Biotherapeutics
    • 10.4.1. Drug description
    • 10.4.2. Other development activities
    • 10.4.3. Clinical development
      • 10.4.3.1. Clinical trial information
    • 10.4.4. Product profile
  • 10.5. ESO-101: EsoCap AG
    • 10.5.1. Drug description
    • 10.5.2. Other development activities
    • 10.5.3. Clinical development
      • 10.5.3.1. Clinical trial information
    • 10.5.4. Product profile

11. Eosinophilic Esophagitis (EoE): Seven Major Market Analysis

  • 11.1. Key Findings
  • 11.2. Total Market Size of EoE in the 7MM
  • 11.3. Market Outlook
  • 11.4. Attribute Analysis
  • 11.5. The United States Market Size
    • 11.5.1. Total Market Size of EoE in the United States
    • 11.5.2. Market Size of EoE in the United States by Therapies
    • 11.5.3. Market Size of EoE in the United States by Class
  • 11.6. The EU5 Market Size
    • 11.6.1. Total Market Size of EOE in the EU5
    • 11.6.2. Market Size of EoE in the EU5 by Therapies
    • 11.6.3. Market Size of EoE in the EU5 by Class
  • 11.7. Japan Market Size
    • 11.7.1. Total Market Size of EoE in Japan
    • 11.7.2. Market Size of EoE in Japan by Therapies
    • 11.7.3. Market Size of EoE in Japan by Class

12. SWOT Analysis

13. KOL Views

14. Unmet Needs

15. Market Access

  • 15.1. The United States
    • 15.1.1. Medicare and Medicaid
    • 15.1.2. Private insurance
    • 15.1.3. Patient access program
  • 15.2. Health Technology Assessment
    • 15.2.1. NICE

16. Acronyms and Abbreviations

17. Appendix

  • 17.1. Bibliography
  • 17.2. Report Methodology

18. DelveInsight Capabilities

19. Disclaimer

20. About DelveInsight

Product Code: DIMI0410

List of Tables

  • Table 1: Summary of EoE, Market, Epidemiology, and Key Events (2019-2032)
  • Table 2: Clinical Manifestations of EoE
  • Table 3: Risk Factors of EoE
  • Table 4: Common Risk Genes with Known Functions
  • Table 5: Diagnostic Criteria for EoE
  • Table 6: Diagnostic Criteria for EoE Proposed in Japan
  • Table 7: Endoscopic Features of EoE
  • Table 8: Novel Diagnostic Approaches
  • Table 9: Conditions Associated with EoE
  • Table 10: GRADE Definitions on the Strength of Recommendation
  • Table 11: GRADE Definitions on Quality of Evidence
  • Table 12: American Gastroenterological Institute and Joint Task Force on Allergy-Immunology Practice Parameters Guideline Recommendations on the Management of EoE
  • Table 13: Knowledge and Evidence Gaps in the Management of EoE
  • Table 14: Summary of European Statements and Recommendations on the Management of EoE
  • Table 15: Total Diagnosed Prevalent Cases of EoE in the 7MM (2019-2032)
  • Table 16: Total Diagnosed Prevalent Cases of EoE in the United States (2019-2032)
  • Table 17: Age-specific Cases of EoE in the United States (2019-2032)
  • Table 18: Gender-specific Cases of EoE in the United States (2019-2032)
  • Table 19: Total Diagnosed Prevalent Cases of EoE in the EU5 (2019-2032)
  • Table 20: Age-specific cases of EoE in the EU5 (2019-2032)
  • Table 21: Gender-specific Cases of EoE in the EU5 (2019-2032)
  • Table 22: Total Diagnosed Prevalent Cases of EoE in Japan (2019-2032)
  • Table 23: Age-specific cases of EoE in Japan (2019-2032)
  • Table 24: Gender-specific cases of EoE in Japan (2019-2032)
  • Table 25: Key Cross of Marketed Products
  • Table 26: Patent Description for DUPIXENT
  • Table 27: Key Cross of Emerging Drugs
  • Table 28: Cendakimab, Clinical Trial Description, 2022
  • Table 29:APT-1011, Clinical Trial Description, 2022
  • Table 30: FASNERA, Clinical Trial Description, 2022
  • Table 31: Key Cross of Other Assets
  • Table 32: Lirentelimab, Clinical Trial Description, 2022
  • Table 33: Etrasimod, Clinical Trial Description, 2022
  • Table 34: IRL201104, Clinical Trial Description, 2022
  • Table 35: ESO-101, Clinical Trial Description, 2022
  • Table 36: Total Market Size of EoE in the 7MM in USD million (2019-2032)
  • Table 37: Weighted Score Based on Ranking
  • Table 38: Market Size of EoE in the United States in USD million (2019-2032)
  • Table 39: Market Size of EoE in the United States by Therapies in USD million (2019-2032)
  • Table 40: Market Size of EoE in the United States by Class in USD million (2019-2032)
  • Table 41: The EU5 Market Size of EoE in USD million (2019-2032)
  • Table 42: Market Size of EoE in the EU5 by Therapies in USD million (2019-2032)
  • Table 43: Market Size of EoE in the EU5 by Class in USD million (2019-2032)
  • Table 44: Total Market Size of EoE in Japan in USD million (2019-2032)
  • Table 45: Market Size of EoE in Japan by Therapies in USD million (2019-2032)
  • Table 46: Market Size of EoE in Japan by Class in USD million (2019-2032)

List of Figures

  • Figure 1: Symptoms of EoE
  • Figure 2: Overview of Potential Considerations in Phenotype and Endotype Classification in EoE
  • Figure 3: Spectrum of EoE Endotypes based on sIgG4 Levels to Cow's Milk (CM) Proteins
  • Figure 4: Genetic Risks Influencing EoE Endotype
  • Figure 5: Overview of EoE Pathophysiology
  • Figure 6: Role of TSLP Gene in EoE Pathogenesis
  • Figure 7: Diagnostic Algorithm of EoE
  • Figure 8: Endoscopic Appearance of EoE
  • Figure 9: Pitfalls in Diagnosing EoE
  • Figure 10: Therapeutic Options of EoE
  • Figure 11: Therapeutic Algorithm for EoE in Clinical Practice
  • Figure 12: Clinical Practice Algorithm for EoE by European Organizations
  • Figure 13: Total Diagnosed Prevalent Cases of EoE in the 7MM (2019-2032)
  • Figure 14: Total Diagnosed Prevalent Cases of EoE in the United States (2019-2032)
  • Figure 15: Age-specific Cases of EoE in the United States (2019-2032)
  • Figure 16: Gender-specific Cases of EoE in the United States (2019-2032)
  • Figure 17: Diagnosed Prevalence of EoE in the EU5 (2019-2032)
  • Figure 18: Age-specific cases of EoE in the EU5 (2019-2032)
  • Figure 19: Gender-specific Cases of EoE in the EU5 (2019-2032)
  • Figure 20: Total Diagnosed Prevalent Cases of EoE in Japan (2019-2032)
  • Figure 21: Age-specific cases of EoE in Japan (2019-2032)
  • Figure 22: Gender-specific cases of EoE in Japan (2019-2032)
  • Figure 23: Total Market Size of EoE in the 7MM (2019-2032)
  • Figure 24: Market Size of EoE in the United States (2019-2032)
  • Figure 25: Market Size of EoE in the United States by Therapies (2019-2032)
  • Figure 26: Market Size of EoE in the United States by Class (2019-2032)
  • Figure 27: The EU5 Market Size of EoE (2019-2032)
  • Figure 28: Market Size of EoE in the EU5 by Therapies (2019-2032)
  • Figure 29: Market Size of EoE in the EU5 by Class (2019-2032)
  • Figure 30: Total Market Size of EoE in Japan (2019-2032)
  • Figure 31: Market Size of EoE in Japan by Therapies (2019-2032)
  • Figure 32: Market Size of EoE in Japan by Class (2019-2032)
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