PUBLISHER: Grand View Research | PRODUCT CODE: 1224608
PUBLISHER: Grand View Research | PRODUCT CODE: 1224608
The global AAV contract development and manufacturing organizations market size is expected to reach USD 4.7 billion by 2035 and it is expected to expand at 17.1% CAGR from 2023 to 2035, according to a new report by Grand View Research, Inc. The main drivers of this market are the robust pipeline of adeno-associated virus (AAV) for gene therapies & vaccines, technological advancements in manufacturing of adeno-associated viral vectors, and a highly competitive market with various strategies undertaken by key market players. For instance, in September 2022, Rocket Pharmaceuticals, Inc. acquired Renovacor, Inc., a biotechnology company, focused on offering precision medicines. This acquisition is in line with the company's aim to strengthen its position as a pioneer in adeno-associated virus (AAV)-based gene therapy for cardiac illness.
AAV-mediated gene therapy products that address fatal and severely disabling diseases have proliferated in recent years, with investment in academic startups, and several products entering clinical trials by major pharmaceutical companies. AAV vector has become a highly effective treatment for cardiovascular, neurological, and immunological illnesses as well as cancer. Due to these factors, market participants and CDMOs implement strategies like M&A, expansions, product launches, collaborations, and partnerships.
Significant advancements have been made in the use of viral vectors within the gene therapy & gene-modified cell therapy fields over the past 10 years. Vendors have innovated existing technologies as part of the industry's ongoing improvement efforts to support the special needs of viral vector manufacturing. These developments include the introduction of iCELLis technology for adherent cell culture and the creation of chromatographic resins for the production of viral vectors. Furthermore, next-generation analytics such as Droplet Digital Polymerase Chain Reaction (ddPCR), Analytical Ultracentrifugation (AUC), Size-Exclusion Chromatography-Multi-Angle Light Scattering (SEC-MALS), and Capillary Electrophoresis-Sodium Dodecyl Sulphate (CE-SDS) facilitate accurate & precise quantification.