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Market Research Report

US Market Report for Orthopedic Bone Graft Substitutes 2017 - MedCore

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US Market Report for Orthopedic Bone Graft Substitutes 2017 - MedCore
Published: March 1, 2017 Content info: 589 Pages
Description

Bone is a biologically active tissue and will regenerate whenever possible; however, there are instances where the damage is significant enough to warrant a scaffold to help rejoin the fissure or cavity. Bone grafting is a surgical procedure in which damaged bone is replaced with autograft tissue, allograft tissue or a bone graft substitute, which can be either synthetic or metal.

During an autograft procedure, tissue is harvested from the patient's iliac crest, or possibly the distal femur or proximal tibia, and placed at the injury site. An allograft procedure uses donated cadaveric tissue. A grafting procedure using a bone graft substitute replaces human tissue with a synthetic or metal material. For the purposes of this report, metal replacement materials will be excluded, as they are not considered biomaterials.

General Report Contents:

  • Market Analyses include: Unit Sales, ASPs, Market Value & Growth Trends
  • Market Drivers & Limiters for each chapter segment
  • Competitive Analysis for each chapter segment
  • Section on recent mergers & acquisitions

As of 2016, the synthetic bone grafts accounted for the largest portion of the market followed by the demineralized bone matrix (DBM) grafts. Market growth has been supported by the strong adoption of the BMP growth factor market, which is represented by Medtronic's INFUSE® product. Furthermore, the fast growing cellular allograft market has benefited the bone graft substitute market by allowing greater osteogenic properties with the use of stem cells. The recent resurgence of growth in the cheaper allograft material market has pushed DBM prices lower in order to stay competitive.

The synthetic bone graft segment surpassed the DBM segment due to both a higher ASP and stronger unit sales growth in the U.S. market. Synthetic grafts are more commonly used in spinal surgeries rather than applications involving larger volumes, as with fracture repair. These large volume indications are the reason that cheaper options, such as allograft bone, play an important role in the market.

Table of Contents
Product Code: iDATA_USOB17_MC_BGS

TABLE OF CONTENTS

TABLE OF CONTENTS

LIST OF FIGURES

LIST OF CHARTS

EXECUTIVE SUMMARY

U.S. ORTHOPEDIC BIOMATERIALS MARKET OVERVIEW

COMPETITIVE ANALYSIS

MARKET TRENDS

MARKET DEVELOPMENTS

PROCEDURE NUMBERS

MARKETS INCLUDED

KEY REPORT UPDATES

VERSION HISTORY

RESEARCH METHODOLOGY

  • 1.1. RESEARCH SCOPE
  • 1.2. IDATA'S 9-STEP METHODOLOGY
    • Step 1: Project Initiation & Team Selection
    • Step 2: Prepare Data Systems and Perform Secondary Research
    • Step 3: Preparation for Interviews & Questionnaire Design
    • Step 4: Performing Primary Research
    • Step 5: Research Analysis: Establishing Baseline Estimates
    • Step 6: Market Forecast and Analysis
    • Step 7: Identify Strategic Opportunities
    • Step 8: Final Review and Market Release
    • Step 9: Customer Feedback and Market Monitoring

DISEASE OVERVIEW

  • 2.1. BASIC ANATOMY
    • 2.1.1. Osteology and Musculoskeletal System
  • 2.2. DISEASE PATHOLOGY AND DISORDERS
    • 2.2.1. General Diagnostic
    • 2.2.2. Osteoporosis
    • 2.2.3. Osteoarthritis
    • 2.2.4. Indication for Bone Graft Procedure
    • 2.2.5. Indication for Cartilage Repair
    • 2.2.6. Degenerative Disc Disease
  • 2.3. PATIENT DEMOGRAPHICS
    • 2.3.1. General Statistics

PRODUCT ASSESSMENT

  • 3.1. PRODUCT PORTFOLIOS
    • 3.1.1. Bone Graft Substitutes
  • 3.2. REGULATORY ISSUES AND RECALLS
    • 3.2.1. Bone Graft Substitutes
  • 3.3. CLINICAL TRIALS
    • 3.3.1. Bone Graft Substitutes

ORTHOPEDIC BONE GRAFT SUBSTITUTE MARKET

  • 4.1. INTRODUCTION
    • 4.1.1. Units per Procedure by Indication
  • 4.2. MARKET OVERVIEW
    • 4.2.1. Bone Graft Substitute Market by Material
    • 4.2.2. Bone Graft Substitute Market by Indication
  • 4.3. MARKET ANALYSIS AND FORECAST
    • 4.3.1. Total Orthopedic Bone Graft Substitute Market
    • 4.3.2. Bone Graft Substitute Market by Material
      • 4.3.2.1. Total Allograft Bone Graft Substitute Market
      • 4.3.2.2. Allograft Bone Graft Substitute Market by Indication
      • 4.3.2.2.1. Spine
      • 4.3.2.2.2. Trauma
      • 4.3.2.2.3. Large Joint Reconstruction
      • 4.3.2.2.4. Foot Reconstruction
      • 4.3.2.2.5. Craniomaxillofacial
      • 4.3.2.2.6. Oncology
      • 4.3.2.3. Total Demineralized Bone Matrix Market
      • 4.3.2.4. Demineralized Bone Matrix Market with and without Carriers
      • 4.3.2.5. Demineralized Bone Matrix Market by Indication
      • 4.3.2.5.1. Spine
      • 4.3.2.5.2. Trauma
      • 4.3.2.5.3. Large Joint Reconstruction
      • 4.3.2.5.4. Foot Reconstruction
      • 4.3.2.5.5. Craniomaxillofacial
      • 4.3.2.5.6. Oncology
      • 4.3.2.6. Total Synthetic Bone Graft Substitute Market
      • 4.3.2.7. Synthetic Bone Graft Substitute Market by Indication
      • 4.3.2.7.1. Spine
      • 4.3.2.7.2. Trauma
      • 4.3.2.7.3. Large Joint Reconstruction
      • 4.3.2.7.4. Foot Reconstruction
      • 4.3.2.7.5. Craniomaxillofacial
      • 4.3.2.7.6. Oncology
    • 4.3.3. Bone Graft Substitute Market by Indication
      • 4.3.3.1. Spine
      • 4.3.3.1.1. Cervical Spine
      • 4.3.3.1.2. Thoracolumbar Spine
      • 4.3.3.2. Trauma
      • 4.3.3.2.1. Non-Union Trauma
      • 4.3.3.2.2. Fresh Fracture Trauma
      • 4.3.3.3. Large Joint Reconstruction
      • 4.3.3.3.1. Hip Large Joint Reconstruction
      • 4.3.3.3.2. Knee Large Joint Reconstruction
      • 4.3.3.4. Foot Reconstruction
      • 4.3.3.5. Craniomaxillofacial
      • 4.3.3.6. Oncology
  • 4.4. DRIVERS AND LIMITERS
    • 4.4.1. Market Drivers
      • 4.4.1.1. Allograft Bone Graft Substitute Market
      • 4.4.1.2. Demineralized Bone Matrix Bone Graft Substitute Market
      • 4.4.1.3. Synthetic Bone Graft Substitute Market
    • 4.4.2. Market Limiters
      • 4.4.2.1. Allograft Bone Graft Substitute Market
      • 4.4.2.2. Demineralized Bone Matrix Bone Graft Substitute Market
      • 4.4.2.3. Synthetic Bone Graft Substitute Market
  • 4.5. COMPETITIVE MARKET SHARE ANALYSIS

ABBREVIATIONS

APPENDIX II: COMPANY PRESS RELEASES

LIST OF CHARTS

  • Chart 1-1: Orthopedic Biomaterials Market by Segment, U.S., 2013 - 2023
  • Chart 1-2: Orthopedic Biomaterials Market Overview, U.S., 2016 & 2023
  • Chart 4-1: Orthopedic Bone Graft Substitute Market by Material, U.S., 2013 - 2023
  • Chart 4-2: Orthopedic Bone Graft Substitute Market Breakdown by Material, U.S., 2016
  • Chart 4-3: Orthopedic Bone Graft Substitute Market Breakdown by Material, U.S., 2023
  • Chart 4-4: Orthopedic Bone Graft Substitute Market by Indication, U.S., 2013 - 2023
  • Chart 4-5: Orthopedic Bone Graft Substitute Market Breakdown by Indication, U.S., 2016
  • Chart 4-6: Orthopedic Bone Graft Substitute Market Breakdown by Indication, U.S., 2023
  • Chart 4-7: Total Orthopedic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-8: Total Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-9: Allograft Bone Graft Substitute Market by Indication, U.S., 2013 - 2023
  • Chart 4-10: Total Spine Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-11: Cervical Spine Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-12: Thoracolumbar Spine Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-13: Total Trauma Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-14: Non-Union Trauma Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-15: Fresh Fracture Trauma Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-16: Large Joint Reconstruction Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-17: Hip Large Joint Reconstruction Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-18: Knee Large Joint Reconstruction Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-19: Foot Reconstruction Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-20: Craniomaxillofacial Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-21: Oncology Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-22: Total Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Chart 4-23: Demineralized Bone Matrix Market by Indication, U.S., 2013 - 2023
  • Chart 4-24: Total Spine Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Chart 4-25: Cervical Spine Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Chart 4-26: Thoracolumbar Spine Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Chart 4-27: Total Trauma Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Chart 4-28: Non-Union Trauma Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Chart 4-29: Fresh Fracture Trauma Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Chart 4-30: Large Joint Reconstruction Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Chart 4-31: Hip Large Joint Reconstruction Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Chart 4-32: Knee Large Joint Reconstruction Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Chart 4-33: Foot Reconstruction Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Chart 4-34: Craniomaxillofacial Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Chart 4-35: Oncology Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Chart 4-36: Total Orthopedic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-37: Synthetic Bone Graft Substitute Market by Indication, U.S., 2013 - 2023
  • Chart 4-38: Spine Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-39: Cervical Spine Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-40: Thoracolumbar Spine Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-41: Total Trauma Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-42: Non-Union Trauma Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-43: Fresh Fracture Trauma Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-44: Large Joint Reconstruction Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-45: Hip Large Joint Reconstruction Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-46: Knee Large Joint Reconstruction Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-47: Foot Reconstruction Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-48: Craniomaxillofacial Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-49: Oncology Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-50: Spine Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-51: Cervical Spine Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-52: Thoracolumbar Spine Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-53: Total Trauma Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-54: Non-Union Trauma Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-55: Fresh Fracture Trauma Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-56: Large Joint Reconstruction Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-57: Hip Large Joint Reconstruction Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-58: Knee Large Joint Reconstruction Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-59: Foot Reconstruction Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-60: Craniomaxillofacial Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-61: Oncology Bone Graft Substitute Market, U.S., 2013 - 2023
  • Chart 4-62: Leading Competitors, Orthopedic Bone Graft Substitute Market, U.S., 2016

LIST OF FIGURES

  • Figure 1-1: Orthopedic Biomaterials Market Share Ranking by Segment, U.S., 2016 (1 of 2)
  • Figure 1-2: Orthopedic Biomaterials Market Share Ranking by Segment, U.S., 2016 (2 of 2)
  • Figure 1-3: Companies Researched in this Report, U.S., 2016
  • Figure 1-4: Factors Impacting the Orthopedic Biomaterials Market by Segment, U.S. (1 of 2)
  • Figure 1-5: Factors Impacting the Orthopedic Biomaterials Market by Segment, U.S. (2 of 2)
  • Figure 1-6: Recent Events in the Orthopedic Biomaterials Market, U.S., 2013 - 2016
  • Figure 1-7: Orthopedic Biomaterials Markets Covered, U.S., 2016 (1 of 2)
  • Figure 1-8: Orthopedic Biomaterials Markets Covered, U.S., 2016 (2 of 2)
  • Figure 1-9: Orthopedic Biomaterials Markets Covered, U.S., 2016(1 of 3)
  • Figure 3-1: Bone Graft Substitutes Products by Company (1 of 3)
  • Figure 3-2: Bone Graft Substitutes Products by Company (2 of 3)
  • Figure 3-3: Bone Graft Substitutes Products by Company (3 of 3)
  • Figure 3-4: Class 2 Device Recall Endobon Xenograft Granules
  • Figure 3-5: Class 2 Device Recall Accell Evo3c Demineralized Bone Matrix Putty
  • Figure 3-6: Class 2 Device Recall AlloFuse DBM Putty 5cc
  • Figure 3-7: Class 2 Device Recall MicroFuse Bone Void Filler
  • Figure 3-8: Class 2 Device Recall Grafton
  • Figure 3-9: Class 2 Device Recall Optimum Expanse
  • Figure 3-10: Class 2 Device Recall Integra Mozaik
  • Figure 3-11: An ACDF Multi-Center Study Using ViviGen Cellular Bone Matrix
  • Figure 3-12: Cerament Treatment of Fracture Defects (CERTiFy)
  • Figure 3-13: Synthetic Bone Graft Substitute vs. Autologous Spongiosa in Revision Anterior Cruciate Ligament Reconstruction
  • Figure 3-14: Assessment of nanOss Bioactive 3D in the Posterolateral Spine
  • Figure 3-15: AttraX® Putty vs. Autograft in XLIF®
  • Figure 3-16: Evaluation of Fusion Rate Using K2M VESUVIUS® Demineralized Fibers With K2M EVEREST® Spinal System
  • Figure 3-17: Clinical Evaluation of GENEX® DS in Instrumented Posterolateral Fusion
  • Figure 3-18: Efficacy and Safety of SurgiFill™ on Spinal Fusion
  • Figure 3-19: Evaluation of DTRAX Graft in Patients With Cervical Degenerative Disc Disease
  • Figure 3-20: Comparison of nanOss Bioactive With Autograft and Bone Marrow Aspirate to Autograft in the Posterolateral Spine
  • Figure 3-21: Evaluation of Fusion Rate of Anterior Cervical Discectomy and Fusion (ACDF) Using Cervios ChronOs™ and Bonion™
  • Figure 4-1: Units per Procedure by Indication, Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-2: Orthopedic Bone Graft Substitute Market by Material, U.S., 2013 - 2023 (US$M)
  • Figure 4-3: Orthopedic Bone Graft Substitute Market by Indication, U.S., 2013 - 2023 (US$M)
  • Figure 4-4: Total Orthopedic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-5: Total Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-6: Allograft Bone Graft Substitute Market by Indication, U.S., 2013 - 2023
  • Figure 4-7: Total Spine Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-8: Cervical Spine Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-9: Thoracolumbar Spine Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-10: Total Trauma Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-11: Non-Union Trauma Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-12: Fresh Fracture Trauma Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-13: Large Joint Reconstruction Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-14: Hip Large Joint Reconstruction Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-15: Knee Large Joint Reconstruction Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-16: Foot Reconstruction Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-17: Craniomaxillofacial Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-18: Oncology Allograft Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-19: Total Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Figure 4-20: Demineralized Bone Matrix Market (with Carriers), U.S., 2013 - 2023
  • Figure 4-21: Demineralized Bone Matrix Market (without Carriers), U.S., 2013 - 2023
  • Figure 4-22: Demineralized Bone Matrix Market by Indication, U.S., 2013 - 2023
  • Figure 4-23: Total Spine Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Figure 4-24: Cervical Spine Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Figure 4-25: Thoracolumbar Spine Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Figure 4-26: Total Trauma Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Figure 4-27: Non-Union Trauma Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Figure 4-28: Fresh Fracture Trauma Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Figure 4-29: Large Joint Reconstruction Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Figure 4-30: Hip Large Joint Reconstruction Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Figure 4-31: Knee Large Joint Reconstruction Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Figure 4-32: Foot Reconstruction Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Figure 4-33: Craniomaxillofacial Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Figure 4-34: Oncology Demineralized Bone Matrix Market, U.S., 2013 - 2023
  • Figure 4-35: Total Orthopedic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-36: Synthetic Bone Graft Substitute Market by Indication, U.S., 2013 - 2023
  • Figure 4-37: Spine Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-38: Cervical Spine Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-39: Thoracolumbar Spine Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-40: Total Trauma Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-41: Non-Union Trauma Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-42: Fresh Fracture Trauma Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-43: Large Joint Reconstruction Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-44: Hip Large Joint Reconstruction Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-45: Knee Large Joint Reconstruction Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-46: Foot Reconstruction Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-47: Craniomaxillofacial Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-48: Oncology Synthetic Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-49: Spine Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-50: Cervical Spine Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-51: Thoracolumbar Spine Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-52: Total Trauma Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-53: Non-Union Trauma Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-54: Fresh Fracture Trauma Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-55: Large Joint Reconstruction Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-56: Hip Large Joint Reconstruction Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-57: Knee Large Joint Reconstruction Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-58: Foot Reconstruction Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-59: Craniomaxillofacial Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-60: Oncology Bone Graft Substitute Market, U.S., 2013 - 2023
  • Figure 4-61: Drivers and Limiters, Orthopedic Bone Graft Substitute Market, U.S., 2016
  • Figure 4-62: Leading Competitors, Orthopedic Bone Graft Substitute Market, U.S., 2016
  • Figure 6-1: Press Release Summary
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