Solubility Enhancement Excipients Market by Product, Type, Application

Description

List of Tables

[190 Pages Report] The Solubility Enhancement Excipients Market size was estimated at USD 3.63 billion in 2023 and expected to reach USD 3.82 billion in 2024, at a CAGR 5.62% to reach USD 5.33 billion by 2030.

Solubility enhancement excipients are a specific category of pharmaceutical ingredients used primarily in the drug manufacturing process to increase the solubility of poorly soluble drug compounds. They play a critical role in bioavailability enhancement, facilitating the dissolution of drugs into the body and thus increasing their therapeutic effectiveness. The rise in chronic diseases and increase in drug discovery and development are accelerating the need for solubility enhancement excipients from the pharmaceutical industries. However, volatility in raw material cost and stringent regulations may adversely impact the use of solubility enhancement excipients by the end-use sectors. Moreover, the proliferation of nanotechnology, the incorporation of bio-based excipients, and the development of multifunctional excipients are expected to create immense potential for the growth of solubility enhancement excipients worldwide.

KEY MARKET STATISTICS
Base Year [2023]	USD 3.63 billion
Estimated Year [2024]	USD 3.82 billion
Forecast Year [2030]	USD 5.33 billion
CAGR (%)	5.62%

Product: Consumer preference for particle size reduction as it provides improved drug loading efficiency

Particle size reduction (PSR) involves reducing the particle size of drug substances or excipients to enhance the surface area and solubility. This process offers considerable advantages, such as improved drug loading efficiency, excellent homogeneity, and improved dissolution rate of drugs, particularly for drugs with poor water solubility. Solid dispersion is the strategy for efficiently encapsulating a hydrophobic drug within a water-soluble carrier matrix. It is preferred when dealing with the formulation of drugs that cannot achieve desired solubility levels through particle size reduction. Particle size reduction is comparatively easier and cost-effective, but it is not effective for all types of drugs, especially those with extremely poor water solubility. Solid dispersion handles tough-to-solubilize such medicines. It needs more complex steps and sophisticated technologies, making it more expensive.

Type: Extensive utilization of surfactants as solubility enhancement excipients to develop surfactant-based drug delivery systems

Lipids are often employed as solubility enhancement excipients due to their no toxicity, biodegradability, and capacity to form various inclusion structures like micelles and liposomes. Polymers are vital in solubility enhancement due to their versatility and relatively inexpensive production costs. Surfactants are ubiquitous due to their capacity to stabilize water-oil interfaces and reduce surface tension, which is critical in enhancing solubility. Lipids are appreciated for their safety and biodegradability, surfactants for their stabilizing properties, and polymers for their affordability and adaptability.

Application: Significant role of solubility enhancement excipients in the pharmaceutical field to drive product excellence

Hospitals are the frontline of the healthcare system, where immediate attention is paramount. A solubility enhancement excipient enables faster absorption of the drug into the body, providing quicker relief to the patient. The pharmaceutical sector requires solubility enhancement excipients to increase the absorption of orally taken drugs and prioritize drug stability, safety, and efficacy in different conditions. Hospitals demand faster absorption for immediate patient relief, while the pharmaceutical sector focuses on drug stability, safety, and effectiveness.

Regional Insights

The solubility enhancement excipients market is evolving in the Americas owing to the well-established pharmaceutical industries, innovations in drug formulation, and technological advancements in drug manufacturing. The Asia Pacific is witnessing significant demand for solubility enhancement excipients due to the increasing prevalence of chronic diseases, the surge in research and development activities, and high generic drug production. Europe, Middle East, and Africa (EMEA) represent high demand for solubility enhancement excipients with strong research and development foundations, ongoing development of novel excipients used in oral administration, and expanding healthcare infrastructure. Besides, technological advancements in the manufacturing of solubility enhancement excipients and ongoing research to improve their properties are anticipated to expand the use of solubility enhancement excipients across the end-use sectors globally.

FPNV Positioning Matrix

The FPNV Positioning Matrix is pivotal in evaluating the Solubility Enhancement Excipients Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

Market Share Analysis

The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Solubility Enhancement Excipients Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

Key Company Profiles

The report delves into recent significant developments in the Solubility Enhancement Excipients Market, highlighting leading vendors and their innovative profiles. These include ABITEC Corporation, Air Liquide S.A., Ashland Global Holdings Inc., BASF SE, Cargill, Incorporated, Clariant International Ltd., Croda International PLC, DuPont de Nemours Inc., Evonik Industries AG, FMC Corporation, FREUND Corporation, Gattefosse, IMCD Group, JRS Pharma GmbH & Co. KG, Kerry Group PLC, Lubrizol Corporation, Merck KGaA, Nippon Soda Co. Ltd., Pharma Excipients International AG, Roquette Freres SA, Shin-Etsu Chemical Co., Ltd., Solvay SA, SPI Pharma Inc., The DOW Chemical Company, and Wacker Chemie AG.

Market Segmentation & Coverage

This research report categorizes the Solubility Enhancement Excipients Market to forecast the revenues and analyze trends in each of the following sub-markets:

Product
- Particle Size Reduction
- Solid Dispersion

Type
- Lipid
- Polymer
- Surfactant

Application
- Hospitals
- Pharmaceuticals

Region
- Americas
  - Argentina
  - Brazil
  - Canada
  - Mexico
  - United States
    - California
    - Florida
    - Illinois
    - New York
    - Ohio
    - Pennsylvania
    - Texas
- Asia-Pacific
  - Australia
  - China
  - India
  - Indonesia
  - Japan
  - Malaysia
  - Philippines
  - Singapore
  - South Korea
  - Taiwan
  - Thailand
  - Vietnam

Europe, Middle East & Africa
- Denmark
- Egypt
- Finland
- France
- Germany
- Israel
- Italy
- Netherlands
- Nigeria
- Norway
- Poland
- Qatar
- Russia
- Saudi Arabia
- South Africa
- Spain
- Sweden
- Switzerland
- Turkey
- United Arab Emirates
- United Kingdom

The report offers valuable insights on the following aspects:

1. Market Penetration: It presents comprehensive information on the market provided by key players.

2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.

3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.

4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.

5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.

The report addresses key questions such as:

1. What is the market size and forecast of the Solubility Enhancement Excipients Market?

2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Solubility Enhancement Excipients Market?

3. What are the technology trends and regulatory frameworks in the Solubility Enhancement Excipients Market?

4. What is the market share of the leading vendors in the Solubility Enhancement Excipients Market?

5. Which modes and strategic moves are suitable for entering the Solubility Enhancement Excipients Market?

Product Code: MRR-62667ADFA2A9

1. Preface

1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders

2. Research Methodology

2.1. Define: Research Objective
2.2. Determine: Research Design
2.3. Prepare: Research Instrument
2.4. Collect: Data Source
2.5. Analyze: Data Interpretation
2.6. Formulate: Data Verification
2.7. Publish: Research Report
2.8. Repeat: Report Update

3. Executive Summary

4. Market Overview

5. Market Insights

5.1. Market Dynamics
- 5.1.1. Drivers
  - 5.1.1.1. Rapid expansion of pharmaceutical industry globally
  - 5.1.1.2. Rising demand for polymer excipients
  - 5.1.1.3. High adoption of solid dispersion technology and need to increase the bioavailability of the API
- 5.1.2. Restraints
  - 5.1.2.1. High cost of solubility enhancement excipients
- 5.1.3. Opportunities
  - 5.1.3.1. Advancements in technology and process analysis for solubility enhancement techniques
  - 5.1.3.2. Novel excipients for solubility enhancement
- 5.1.4. Challenges
  - 5.1.4.1. Adverse effects associated with the use of excipients
5.2. Market Segmentation Analysis
- 5.2.1. Product: Consumer preference for particle size reduction as it provides improved drug loading efficiency
- 5.2.2. Type: Extensive utilization of surfactants as solubility enhancement excipients to develop surfactant-based drug delivery systems
- 5.2.3. Application: Significant role of solubility enhancement excipients in the pharmaceutical field to drive product excellence
5.3. Market Disruption Analysis
5.4. Porter's Five Forces Analysis
- 5.4.1. Threat of New Entrants
- 5.4.2. Threat of Substitutes
- 5.4.3. Bargaining Power of Customers
- 5.4.4. Bargaining Power of Suppliers
- 5.4.5. Industry Rivalry
5.5. Value Chain & Critical Path Analysis
5.6. Pricing Analysis
5.7. Technology Analysis
5.8. Patent Analysis
5.9. Trade Analysis
5.10. Regulatory Framework Analysis

6. Solubility Enhancement Excipients Market, by Product

6.1. Introduction
6.2. Particle Size Reduction
6.3. Solid Dispersion

7. Solubility Enhancement Excipients Market, by Type

7.1. Introduction
7.2. Lipid
7.3. Polymer
7.4. Surfactant

8. Solubility Enhancement Excipients Market, by Application

8.1. Introduction
8.2. Hospitals
8.3. Pharmaceuticals

9. Americas Solubility Enhancement Excipients Market

9.1. Introduction
9.2. Argentina
9.3. Brazil
9.4. Canada
9.5. Mexico
9.6. United States

10. Asia-Pacific Solubility Enhancement Excipients Market

10.1. Introduction
10.2. Australia
10.3. China
10.4. India
10.5. Indonesia
10.6. Japan
10.7. Malaysia
10.8. Philippines
10.9. Singapore
10.10. South Korea
10.11. Taiwan
10.12. Thailand
10.13. Vietnam

11. Europe, Middle East & Africa Solubility Enhancement Excipients Market

11.1. Introduction
11.2. Denmark
11.3. Egypt
11.4. Finland
11.5. France
11.6. Germany
11.7. Israel
11.8. Italy
11.9. Netherlands
11.10. Nigeria
11.11. Norway
11.12. Poland
11.13. Qatar
11.14. Russia
11.15. Saudi Arabia
11.16. South Africa
11.17. Spain
11.18. Sweden
11.19. Switzerland
11.20. Turkey
11.21. United Arab Emirates
11.22. United Kingdom

12. Competitive Landscape

12.1. Market Share Analysis, 2023
12.2. FPNV Positioning Matrix, 2023
12.3. Competitive Scenario Analysis
- 12.3.1. Clariant Launches New Range Of Excipients To Improve Stability and Solubility of APIs at CPHI Barcelona
- 12.3.2. Lubrizol Launches Innovative Apisolex Technology to Improve Solubility & Simplify Manufacturing of Parenteral Drug Products
- 12.3.3. Hovione and Zerion Pharma Announce a Strategic Partnership to Market the Dispersome Technology Platform
12.4. Strategy Analysis & Recommendation

13. Competitive Portfolio

13.1. Key Company Profiles
13.2. Key Product Portfolio