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Market Research Report

qPCR and dPCR Markets (Instruments, Reagents, Software/Services)

Published by Kalorama Information Product code 317962
Published Content info 190 Pages
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qPCR and dPCR Markets (Instruments, Reagents, Software/Services)
Published: April 26, 2016 Content info: 190 Pages
Description

PCR, or polymerase chain reaction, is used to amplify a single copy or a few copies of a piece of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence. The most notable use of qPCR is DNA sequencing and gene expression in research applications. qPCR is used in a variety of research areas including stem cell research, oncology and genetic disease research, pathogen detection and infectious disease research, plant sciences research and many others.

This report, qPCR and dPCR Markets contains essential market information for business planning and strategy, including the following:

  • qPCR Market, 2015-2020
  • dPCR Market, 2015-2020
  • Market by Product Type (Reagents, Instruments, Software Services, Total, Percent Change)
  • Market Share by Use, 2015 (Clinical, Research, Other)
  • Market Share by Geographic Region, 2013 (U.S., Europe, Japan, ROW)
  • Selected qPCR and dPCR based MolecularTests in Development
  • Company Profiles
  • Overview of Product Offerings
  • Regulatory Structure and Background Information
  • Trends in the qPCR and dPCR market

qPCR is increasingly being used in the clinical/medical diagnostic arena for diagnosis of bacterial disease, detection of antibiotic resistance, diagnosis of infectious disease and quantification of bacterial load. It is also used to detect genetic abnormalities and cancer mutations. qPCR-based diagnostic tests are expected to expand in the coming years. However, these tests will have to meet three requirements: adaptation of existing diagnostic tests, especially according to the discovery of new variants of target genes of specific pathogens, responsible for false-negative results; expansion of diagnostic applications; and lower cost.

In this report, product offerings are reviewed in three areas

  • Instruments: Thermocyclers or DNA amplifiers. Quality thermocyclers contain silver blocks to facilitate fast temperature changes and uniform temperature throughout the block. Other thermocyclers have multiple blocks with high heat capacity; each block is kept at a constant temperature and the reaction tubes are moved between them automatically. Roche, Thermo Fisher Scientific, Bio-Rad, Agilent Technologies, Analytik Jena, Eppendorf, Biometra , QIAGEN, Cepheid, Sacace,Takara Bio, Fluidigm, WaferGen Biosystems, Deville Scientific, RainDance Technologies, Bibby Scientific, Abbott Molecular, Kyratec, Mobidiag are among the makers of thermocyclers covered in this report.
  • Reagents: A measurable signal has to be generated in the target sample. To accomplish this, fluorescent technologies are used to detect the amplified product. Some of them are non-specific; others are specific chemistries that can distinguish between nonspecific amplification and target amplification. The detection methods most often used include:SYBR Green I, High Resolution Melting dyes (HRM dyes), TaqMan probes LNA Double-Dye probes, Molecular Beacon probes, FRETT probes and others
  • Software: Since its introduction, quantitative real-time polymerase chain reaction (qPCR) has become the standard method for quantification of gene expression. Its high sensitivity, large dynamic range, and accuracy led to the development of numerous applications with an increasing number of samples to be analyzed.

Most of the major companies such as Thermo Fisher Scientitic, Agilent, Roche and Bio-Rad offer qPCR software and services. Agilent - MXPro ET QPCR Thermo Fisher's Melt Software, Real Time Stat Miner Software, DataAssist. Bio-Rad - CFX Manager Software

There are a number of issues and trends affecting the total PCR Technologies industry. Some of these issues are affecting the entire medical industry such as an aging population, healthcare reform while others are unique to the qPCR and dPCR. The issues and trends affecting this market are:

  • Population Demographics
  • Disease and Aging
  • Healthcare Reform
  • BRIC Involvement
  • Regulatory Structure
  • qPCR and Robotics
  • Lab-on-a-Chip Devices
  • Molecular Testing Reimbursement
  • Molecular Tests

LEADING COMPETITORS

The majority of competitive participation for PCR technologies in the United States and Europe. However, competition is steadily escalating in the United States and Europe, which is encouraging more participation in other areas such as Asia and Latin America. There are numerous companies in the market which include large multiproduct companies such as Thermo Fisher Scientific, Roche and Abbott and small niche developers such as RainDance Technologies.

Companies profiles in this report include:

  • Abbott Laboratories
  • Affymetrix
  • Agilent Technologies
  • Analytik Jena AG
  • Beckman Coulter
  • Becton Dickinson
  • BioFire Diagnostics
  • BioMeme
  • bioMerieux
  • Bio-Rad Laboratories
  • Cepheid
  • Denville Scientific
  • Eppendorf AG
  • Exiqon A/S
  • Fluidigm
  • Illumina
  • Kyratec
  • Mobidiag Ltd.
  • Promega
  • QIAGEN
  • RainDance Technologies
  • Roche
  • Sacace Biotechnologies
  • Seegene
  • Takaro Bio
  • Thermo Fisher Scientific
  • WaferGen Biosystems
Table of Contents
Product Code: KLI15004171

Table of Contents

CHAPTER ONE: EXECUTIVE SUMMARY

  • Overview
  • Scope and Methodology
  • Total Size and Growth of the Market
  • Issues and Trends Affecting Market
  • Leading Competitors

CHAPTER TWO: INTRODUCTION TO PCR TECHNOLOGIES: REAL TIME QPCR AND THE DPCR INDUSTRY

  • Overview
  • Definitions
  • Polymerase Chain Reaction
  • PCR Applications
  • qPCR
  • Digital PCR
  • Droplet Digital PCR
  • Personalized Medicine
  • Potential Benefits
  • Privacy and Public Perception

CHAPTER THREE: INDUSTRY TRENDS

  • The Health Industry
  • HEALTHCARE SPENDING TRENDS
  • POPULATION STATISTICS
  • Global Population Trends
  • Chronic Disease Impact
  • Disease and An Aging Population
  • Healthcare Reform in the United States
  • BRIC Involvement
  • Regulatory Structure
  • qPCR and Robotics
  • Lab-on-a Chip (LOC) Devices
  • Molecular Test Reimbursement
  • Molecular tests

CHAPTER FOUR: REAL TIME QPCR AND DPCR PRODUCTS

  • Select Reagents
  • Select Thermocyclers Instruments
  • Selected Reagent and Thermocycler Suppliers
  • Select Software and Services

CHAPTER FIVE: MARKET SIZE AND GROWTH

  • Market Considerations
  • Market Overview
  • PCR Technologies: qPCR and dPCR Market by Technology
  • qPCR Market by Use
  • qPCR Market by Product Type
  • dPCR Market by Product Type
  • PCR Technologies: qPCR and dPCR Market by Geographical Region
  • Competitive Landscape

CHAPTER SIX: COMPANY PROFILES

  • Introduction
  • Abbott Laboratories
  • Company Overview
  • Affymetrix
  • Company Overview
  • Agilent Technologies
  • Company Overview
  • Analytik Jena AG
  • Company Overview
  • Beckman Coulter, Inc
  • Company Overview
  • Beckton Dickinson & Co
  • Company Overview
  • BioFire Diagnostics, Inc
  • Company Overview
  • BioMeme, Inc
  • Company Overview
  • bioMerieux SA
  • Company Overview
  • Bio-Rad Laboratories, Inc
  • Company Overview
  • Cepheid, Inc.
  • Company Overview
  • Denville Scientific, Inc
  • Company Overview
  • Eppendorf AG
  • Company Overview
  • Exiqon A/S
  • Company Overview
  • Fluidigm Corporation
  • Company Overview
  • Kyratec
  • Company Overview
  • Mobidiag Ltd.
  • Company Overview
  • Promega Corporation
  • Company Overview
  • QIAGEN N.V.
  • Company Overview
  • RainDance Technologies
  • Company Overview
  • Roche
  • Company Overview
  • SACACE BIOTECHNOLOGIES S. R. L.
  • Company Overview
  • SEEGENE, INC
  • Company Overview
  • Takaro Bio, Inc
  • Company Overview
  • Thermo Fisher Scientific
  • Company Overview
  • WaferGen Biosystems, Inc
  • Company Overview

LIST OF CONTRIBUTORS

LIST OF EXHIBITS

CHAPTER ONE: EXECUTIVE SUMMARY

  • Table 1-: The PCR Technologies Market 2013-2020
  • Figure 1-1: The PCR Technologies Market 2013-2020

CHAPTER TWO: INTRODUCTION

  • Table 2-1: PCR Technologies Comparison

CHAPTER THREE: INDUSTRY TRENDS

  • Table 3-1: Total Healthcare Expenditures as a Percent of GDP by Country 1990, 2000 and 2011
  • Figure 3-1: Total Healthcare Expenditures as a Percent of GDP by Country 1990, 2000, and 2011
  • Table 3-2: Global Population and Average Annual Change, 2005 - 2050
  • Figure 3-2: The Global Population, 2005-2050
  • Table 3-3: Global Population Trends Age 65+, 2000-2050
  • Figure 3-3: Global Population Trends Age 65+, 2000-2050
  • Table 3-4: Selected Disease Statistics, Worldwide, as of July 2015
  • Figure 3-4: Elderly Support Ratio in Selected Countries (2050)
  • Table 3-5: Available Market Data, mid-2014
  • Table 3-6: BRIC Healthcare Infrastructure Capacity
  • Table 3-7: Selected qPCR and dPCR based Molecular Tests in Development

CHAPTER FIVE: MARKET SIZE AND GROWTH

  • Table 5-1: The PCR Technologies: qPCR and dPCR Market 2013-2020
  • Figure 5-1: The PCR Technologies: qPCR and dPCR Market 2013-2020
  • Table 5-2: The PCR Technologies: qPCR and dPCR Market 2013-2020
  • Figure 5-2: The PCR Technologies: qPCR and dPCR Market 2013-2020
  • Table 5-3: The PCR Technologies: qPCR and dPCR Market by Product Type 2013-2020
  • Figure 5-3: The PCR Technologies: qPCR and dPCR Market Revenues\ by Product Type 2013-2020
  • Figure 5-4: The qPCR Market Share by Use, 2015 (Clinical/Research)
  • Figure 5-5: The dPCR Market Share by Use, 2015
  • Table 5-4: The qPCR Market by Product Type 2013-2020
  • Figure 5-6: The qPCR Market by Product Type 2015
  • Table 5-5: The dPCR Market by Product Type 2013-2020
  • Figure 5-7: The Total dPCR Market by Product Type 2015
  • Figure 5-8: The PCR Technologies: qPCR and dPCR Market Estimated Market Share by Geographic Region, 2015
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