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PUBLISHER: Roots Analysis | PRODUCT CODE: 1067327

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PUBLISHER: Roots Analysis | PRODUCT CODE: 1067327

Single-Use Upstream Bioprocessing Technology / Equipment Market by Type of Product (Single-use Bioreactors, Single-use Mixers, Single-use Media Bags, Single-use Filters, Single-use Sampling Systems, Single-use Connectors and Others), Scale of Operation

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Title:
Single-Use Upstream Bioprocessing Technology / Equipment
Market by Type of Product (Single-use Bioreactors, Single-use Mixers, Single-use Media Bags, Single-use Filters, Single-use Sampling Systems, Single-use Connectors and Others), Scale of Operation (Preclinical / Clinical and Commercial) and Key Geographical Regions (North America, Europe, Asia-Pacific, Latin-America, Middle East and North Africa and Rest of the World): Industry Trends and Global Forecasts, 2022-2035.

Example Insights:

Overview

Over time, biologics have gained significant popularity owing to their therapeutic efficacy, favorable safety profiles and ability to treat a wide variety of disease indications, which are otherwise hard to treat. The success of these interventions has prompted the stakeholders to upgrade the traditional biologics manufacturing technology. The demand for increasing productivity and flexibility, greater profitability and faster time to market are further driving the replacement of traditional stainless-steel equipment with single-use technologies. These technologies have been well-accepted in relatively shorter period of time and have become an important tool in the development of various biotechnological processes. Moreover, the ongoing COVID-19 pandemic has prompted the biopharmaceutical industry to shift to single-use technology. These technologies not only lower down the footprint requirement but also eliminate the cleaning costs in developmental stage. Additionally, the single-use technologies have the potential to address a number of challenges associated with traditional bioprocessing systems and offer various additional benefits, such as reduced water and energy consumption (by ~45%), lower initial investment cost (by 40%), lesser time for processing of biologics (by 33%), decreased risk of cross-contamination (by 8%) and increased cost saving potential (by 30-40%).

Presently, several companies are engaged in developing and manufacturing single-use upstream bioprocessing technologies and equipment, such as single-use bioreactors, single-use mixers, single-use filters, single-use media bags and containers, single-use sampling systems and single-use connectors. Further, a number of these players are also focusing on incorporating additional features, including provisions for alerts / alarms, built-in system process control sensors, electronic process logs, remote monitoring features, touch screens, and advanced safety provisions, in their proprietary offerings. The adoption of this technology is fraught with some challenges, such as risk of extractables and leachable, single-use technology disposability, sterilization / irradiation issues and potential inconsistency of the resins, however, owing to the ongoing research on sustainability of this technology and other technical advancements, we are led to believe that the opportunity for technology providers engaged in this domain is likely to grow in the foreseen future.

Scope of the Report

The "Single-Use Upstream Bioprocessing Technology / Equipment Market by Type of Product (Single-use Bioreactors, Single-use Mixers, Single-use Media Bags, Single-use Filters, Single-use Sampling Systems, Single-use Connectors and Others), Scale of Operation (Preclinical / Clinical and Commercial) and Key Geographical Regions (North America, Europe, Asia-Pacific, Latin-America, Middle East and North Africa and Rest of the World): Industry Trends and Global Forecasts, 2022-2035" report features an extensive study of the current landscape and the likely future potential of single-use upstream bioprocessing technology and equipment developers, over the next 15 years. The study also features an in-depth analysis, highlighting the capabilities of various industry stakeholders engaged in this field. In addition to other elements, the study includes:

  • A detailed assessment of the overall market landscape of single-use bioreactors based on a number of relevant parameters, such as scale of operation (lab, clinical and commercial), type of cell culture system (2D culture and 3D culture), type of cell culture (mammalian, insect, microbial, viral, plant and others), type of molecule (vaccine, monoclonal antibody, recombinant protein, stem cell, cell therapy, gene therapy and others), key features (touch screen, remote monitoring, build-in system control sensors, electronic log record, alarm system), application area (stem cell research, cancer research, regenerative medicine, drug discovery and others) and end users (pharma / biopharma, contract manufacturing organization, contract research organization and academic institutes). In addition, it presents details of the companies developing single-use bioreactors, highlighting their year of establishment, company size, and geographical presence.
  • A detailed assessment of the overall market landscape of single-use mixers based on a number of relevant parameters, such as scale of operation (lab, clinical and commercial), type of mixing system (liquid / liquid, solid / liquid and powder / liquid), type of molecule (vaccines, biologics, biosimilars and monoclonal antibody), key features (visual display / touch screen, ease to use / scalability, build-in system control sensors and process automation) and application area (media preparation, formulation, buffer preparation, viral inactivation and others). In addition, it presents details of the companies developing single-use bioreactors, highlighting their year of establishment, company size, and geographical presence.
  • A detailed assessment of the overall market landscape of single-use sensors, based on several relevant parameters, such as type of sensor (conductivity, flow, pH, pressure and temperature), type of bioprocessing, measurement range, operating temperature, sterilization technique, material used) and application area. In addition, the chapter presents details of the companies involved in the development of single-use sensors, including information on their year of establishment, company size, and geographical presence.
  • An overview of the overall market landscape of other single-use technologies, such as filters, sampling systems and connectors.
  • A detailed competitiveness analysis of single-use bioreactors, single-use mixers and single-use sensors, taking into consideration several relevant parameters. For single-use bioreactors, the parameters taken into account include the product applicability (type of cell culture, type of molecule and application area) and product strength (type of cell culture system, scale of operation and key features). For single-use mixers, the parameters taken into account include the product applicability (type of mixing system, type of molecule and application area) and product strength (scale of operation). For single-use sensors, the parameters taken into account include the product specificity (minimum operating temperature, maximum operating temperature, type of calibration and type of sterilization technique) and product strength (application area and type of bioprocessing).
  • Tabulated profiles of the key players providing single-use upstream bioprocessing technologies, which are headquartered in North America, Europe and Asia-Pacific. Each profile includes an overview of the company, information on the financial performance (if available), service portfolio, product portfolio, recent developments, and an informed future outlook.
  • An in-depth analysis of various patents that have been filed / granted for single-use upstream bioprocessing technology, till December 2021, highlighting key trends associated with these patents, across type of patents, publication year, application year, issuing authorities involved, type of organizations, emerging focus area, patent age, CPC symbols, leading patent assignees (in terms of number of patents granted / filed), patent characteristics and geography. It also includes a detailed patent benchmarking and an insightful valuation analysis.
  • A detailed brand positioning analysis of the key industry players (including single-use bioreactor developers, single-use mixers developers and single-use sensors developers), highlighting the current perceptions regarding their proprietary products by taking into consideration several relevant aspects, such as experience of the manufacturer, number of products offered, product diversity, and number of patents published.
  • An insightful analysis of the cost and time saving potential of single-use upstream bioprocessing technology.
  • An informed estimate on the current and future demand-supply scenario for single-use upstream bioprocessing technologies, for the period 2022-2035.

One of the key objectives of the report was to understand the primary growth drivers and estimate the future size of single-use upstream bioprocessing technology / equipment market. Based on multiple parameters, such as overall upstream bioprocessing equipment market, and share of single-use technology, we have provided an informed estimate of the evolution of the market for the period 2022-2035. Our year-wise projections of the current and future opportunity have further been segmented on the basis of [A] scale of operation (preclinical / clinical and commercial), [B] type of product (single-use bioreactors, single-use mixers, single-use media bags, single-use filters, single-use sampling systems, single-use connectors and others), and [C] key geographical regions (North America, Europe, Asia-Pacific, Latin America, MENA and Rest of the World). In order to account for future uncertainties and to add robustness to our model, we have provided three forecast scenarios, namely conservative, base and optimistic scenarios, representing different tracks of the industry's growth.

The opinions and insights presented in this study were also influenced by discussions held with senior stakeholders in the industry. The report features detailed transcripts of interviews held with the following industry players:

  • Christopher Brau (R&D Staff Scientist and Engineer, Thermo Fisher Scientific)
  • Nico Oosterhuis (Technical Director and Co-Owner, Celltainer Biotech)

All actual figures have been sourced and analyzed from publicly available information forums and primary research discussions. Financial figures mentioned in this report are in USD, unless otherwise specified.

Key Questions Answered:

  • Who are the leading players offering single-use upstream bioprocessing technologies?
  • What are the different application areas where single-use upstream bioprocessing technologies can be used?
  • In which regions majority of the single-use upstream bioprocessing technology providers are located?
  • What is the relative competitiveness of different single-use upstream bioprocessing technologies?
  • What are the key features of single-use bioreactors?
  • How has the intellectual property landscape of single-use upstream bioprocessing technologies, evolved over the years?
  • What is the current demand and supply of biologics manufacturing through single-use upstream bioprocessing technology?
  • How is the current and future opportunity likely to be distributed across key market segments?

Chapter Outlines

Chapter 2 is an executive summary of the key insights captured in our research. It offers a high-level view on the current state of the single-use upstream bioprocessing technology market and its likely evolution in the short to mid-term and long term.

Chapter 3 provides a general introduction to bioprocessing industry, covering details related to the current trends in the domain. The chapter provides details on the historical evolution of single-use technology and different types of single-use equipment. It emphasizes on various advantages and key challenges associated with the single-use technologies. In addition, it discusses implementation strategies of the single-use upstream bioprocessing technology and future prospects.

Chapter 4 provides a detailed assessment of the overall market landscape of single-use bioreactors based on a number of relevant parameters, such as scale of operation (lab, clinical and commercial), type of cell culture system (2D culture and 3D culture), type of cell culture (mammalian, insect, microbial, viral, plant and others), type of molecule (vaccine, monoclonal antibody, recombinant protein, stem cell, cell therapy, gene therapy and others), key features (touch screen, remote monitoring, build-in system control sensors, electronic log record, alarm system), application area (stem cell research, cancer research, regenerative medicine, drug discovery and others) and end users (pharma / biopharma, contract manufacturing organization, contract research organization and academic institutes). In addition, it presents details of the companies developing single-use bioreactors, highlighting their year of establishment, company size, and geographical presence.

Chapter 5 provides a detailed assessment of the overall market landscape of single-use mixers based on a number of relevant parameters, such as scale of operation (lab, clinical and commercial), type of mixing system (liquid / liquid, solid / liquid and powder / liquid), type of molecule (vaccines, biologics, biosimilars and monoclonal antibody), key features (visual display / touch screen, ease to use / scalability, build-in system control sensors and process automation) and application area (media preparation, formulation, buffer preparation, viral inactivation and others). In addition, it presents details of the companies developing single-use bioreactors, highlighting their year of establishment, company size, and geographical presence.

Chapter 6 provides a detailed assessment of the overall market landscape of single-use sensors, based on several relevant parameters, such as type of sensor (conductivity, flow, pH, pressure and temperature), type of bioprocessing, measurement range, operating temperature, sterilization technique, material used) and application area. In addition, the chapter presents details of the companies involved in the development of single-use sensors, including information on their year of establishment, company size, and geographical presence.

Chapter 7 features a tabulated section presenting the overall market landscape of other single-use technologies, such as filters, sampling systems and connectors.

Chapter 8 features a detailed competitiveness analysis of single-use bioreactors, single-use mixers and single-use sensors, taking into consideration several relevant parameters. For single-use bioreactors, the parameters taken into account include the product applicability (type of cell culture, type of molecule and application area) and product strength (type of cell culture system, scale of operation and key features). For single-use mixers, the parameters taken into account include the product applicability (type of mixing system, type of molecule and application area) and product strength (scale of operation). For single-use sensors, the parameters taken into account include the product specificity (minimum operating temperature, maximum operating temperature, type of calibration and type of sterilization technique) and product strength (application area and type of bioprocessing).

Chapter 9 features tabulated profiles of the key players providing single-use upstream bioprocessing technologies, which are headquartered in North America. Each profile includes an overview of the company, information on the financial performance (if available), service portfolio, product portfolio, recent developments, and an informed future outlook.

Chapter 10 features tabulated profiles of the key players providing single-use upstream bioprocessing technologies, which are headquartered in Europe. Each profile includes an overview of the company, information on the financial performance (if available), service portfolio, product portfolio, recent developments, and an informed future outlook.

Chapter 11 features tabulated profiles of the key players providing single-use upstream bioprocessing technologies, which are headquartered in Asia-Pacific. Each profile includes an overview of the company, information on the financial performance (if available), service portfolio, product portfolio, recent developments, and an informed future outlook.

Chapter 12 presents an in-depth analysis of various patents that have been filed / granted for single-use upstream bioprocessing technology, till December 2021, highlighting key trends associated with these patents, across type of patents, publication year, application year, issuing authorities involved, type of organizations, emerging focus area, patent age, CPC symbols, leading patent assignees (in terms of number of patents granted / filed), patent characteristics and geography. It also includes a detailed patent benchmarking and an insightful valuation analysis.

Chapter 13 provides a detailed brand positioning analysis of the key industry players (including single-use bioreactor developers, single-use mixers developers and single-use sensors developers), highlighting the current perceptions regarding their proprietary products by taking into consideration several relevant aspects, such as experience of the manufacturer, number of products offered, product diversity, and number of patents published.

Chapter 14 presents an insightful analysis of the cost and time saving potential of single-use upstream bioprocessing technology.

Chapter 15 provides an informed estimate on the current and future demand and supply of biologics manufactured using single-use upstream bioprocessing technologies, for the period 2022-2035.

Chapter 16 features a comprehensive market forecast analysis, highlighting the future potential of the market till 2035, based on multiple parameters, such as overall upstream bioprocessing equipment market, and share of single-use technology. It includes an informed estimate of the evolution of the market for the period 2022-2035. We have segregated the current and future opportunity have further been segmented on the basis of [A] scale of operation (preclinical / clinical and commercial), [B] type of product (single-use bioreactors, single-use mixers, single-use media bags, single-use filters, single-use sampling systems, single-use connectors and others), and [C] key geographical regions (North America, Europe, Asia-Pacific, Latin America, MENA and Rest of the World). It is worth mentioning that we adopted a top-down approach for this analysis, backing our claims with relevant datapoints and credible inputs from primary research.

Chapter 17 is the summary of the overall report, which presents insights on the contemporary market trends and the likely evolution of the single-use upstream bioprocessing market.

Chapter 18 is a collection of interview transcripts of discussions held with various key stakeholders in this market. The chapter provides a brief overview of the company and details of the interview held with Christopher Brau (R&D Staff Scientist and Engineer, Thermo Fisher Scientific) and Nico Oosterhuis (Technical Director and Co-Owner, Celltainer Biotech).

Chapter 19 is an appendix, which provides tabulated data and numbers for all the figures provided in the report.

Chapter 20 is an appendix, which contains the list of companies and organizations mentioned in the report.

TABLE OF CONTENTS

1. PREFACE

  • 1.1. Overview
  • 1.2. Scope of the Report
  • 1.3. Research Methodology
  • 1.4. Key Questions Answered
  • 1.5. Chapter Outlines

2. EXECUTIVE SUMMARY

3. INTRODUCTION

  • 3.1. Chapter Overview
  • 3.2. Overview of Single-use Upstream Bioprocessing Technology
  • 3.3. Historical Evolution of Single-use Upstream Bioprocessing Technology
  • 3.4. Types of Single-use Upstream Bioprocessing Technology
  • 3.5. Applications of Single-use Upstream Bioprocessing Technology
  • 3.6. Key Challenges Associated with Single-use Upstream Bioprocessing Technology
  • 3.7. Future Perspective

4. MARKET LANDSCAPE: SINGLE-USE BIOREACTORS

  • 4.1. Chapter Overview
  • 4.2. Single-use Bioreactors: List of Products
    • 4.2.1. Analysis by Type of Bioreactor
    • 4.2.2. Analysis by Scale of Operation
    • 4.2.3. Analysis by Type of Cell Culture System
    • 4.2.4. Analysis by Type of Cell Culture
    • 4.2.5. Analysis by Type of Molecule Processed
    • 4.2.6. Analysis by Key Features
    • 4.2.7. Analysis by Application Area
    • 4.2.8. Analysis by End Users
  • 4.3. Single-use Bioreactors: Developer Landscape
    • 4.3.1. Analysis by Year of Establishment
    • 4.3.2. Analysis by Company Size
    • 4.3.2. Analysis by Year of Establishment and Company Size
    • 4.3.3. Analysis by Location of Headquarters
    • 4.3.4. Leading Developers: Analysis by Number of Single-use Bioreactors

5. MARKET LANDSCAPE: SINGLE-USE MIXERS

  • 5.1. Chapter Overview
  • 5.2. Single-use Mixers: List of Products
    • 5.2.1. Analysis by Scale of Operation
    • 5.2.2. Analysis by Type of Mixing System
    • 5.2.3. Analysis by Stage of Bioprocessing
    • 5.2.4. Analysis by Type of Molecule Processed
    • 5.2.5. Analysis by Key Features
    • 5.2.6. Analysis by Application Area
  • 5.3. Single-use Mixers: Developer Landscape
    • 5.3.1. Analysis by Year of Establishment
    • 5.3.2. Analysis by Company Size
    • 5.3.3. Analysis by Location of Headquarters
    • 5.3.4. Analysis by Year of Establishment and Location of Headquarters
    • 5.3.5. Leading Developers: Analysis by Number of Single-use Mixers

6. MARKET LANDSCAPE: SINGLE-USE SENSORS

  • 6.1. Chapter Overview
  • 6.2. Single-use Sensors: List of Products
  • 6.2.1 Analysis by Type of Sensor
    • 6.2.2. Analysis by Stage of Bioprocessing
    • 6.2.3. Analysis by Operating Temperature
    • 6.2.4. Analysis by Sterilization Technique
    • 6.2.5. Analysis by Sensor Calibration
    • 6.2.6. Analysis by Type of Material Used
    • 6.2.7. Analysis by Application Area
  • 6.3. Single-use Sensors: Developer Landscape
    • 6.3.1. Analysis by Year of Establishment
    • 6.3.2. Analysis by Company Size
    • 6.3.3. Analysis by Location of Headquarters
    • 6.3.4. Leading Developers: Analysis by Number of Single-use Sensors

7. MARKET LANDSCAPE: OTHER SINGLE-USE UPSTREAM BIOPROCESSING TECHNOLOGIES

  • 7.1. Chapter Overview
  • 7.2. Single-use Media Bags and Containers
  • 7.3. Single-use Filters
  • 7.4. Single-use Sampling Systems
  • 7.5. Single-use Connectors

8. PRODUCT COMPETITIVENESS ANALYSIS

  • 8.1. Chapter Overview
  • 8.2. Methodology
  • 8.3. Assumptions / Key Parameters
  • 8.4. Product Competitiveness Analysis: Single-use Bioreactors
    • 8.4.1. Companies Headquartered in North America
    • 8.4.2. Companies Headquartered in Europe
    • 8.4.3. Companies Headquartered in Asia-Pacific and Rest of the World
  • 8.5. Product Competitiveness Analysis: Single-use Mixers
    • 8.5.1. Companies Headquartered in North America
    • 8.5.2. Companies Headquartered in Europe
    • 8.5.3. Companies Headquartered in Asia-Pacific and Rest of the World
  • 8.6. Product Competitiveness Analysis: Single-use Sensors
    • 8.6.1. Companies Headquartered in North America
    • 8.6.2. Companies Headquartered in Europe
    • 8.6.3. Companies Headquartered in Asia-Pacific and Rest of the World

9. SINGLE-USE UPSTREAM BIOPROCESSING TECHNOLOGY PROVIDERS IN NORTH AMERICA: COMPANY PROFILES

  • 9.1. Chapter Overview
  • 9.2. Avantor
    • 9.2.1. Company Overview
    • 9.2.2. Financial Information
    • 9.2.3. Service Portfolio
    • 9.2.4. Product Portfolio
    • 9.2.5. Recent Developments and Future Outlook
  • 9.3. Cytiva
    • 9.3.1. Company Overview
    • 9.3.2. Financial Information
    • 9.3.3. Service Portfolio
    • 9.3.4. Product Portfolio
    • 9.3.5. Recent Developments and Future Outlook
  • 9.4. Merck KGaA
    • 9.4.1. Company Overview
    • 9.4.2. Financial Information
    • 9.4.3. Service Portfolio
    • 9.4.4. Product Portfolio
    • 9.4.5. Recent Developments and Future Outlook
  • 9.5. Pall
    • 9.5.1. Company Overview
    • 9.5.2. Financial Information
    • 9.5.3. Service Portfolio
    • 9.5.4. Product Portfolio
    • 9.5.5. Recent Developments and Future Outlook
  • 9.6. Thermo Fisher Scientific
    • 9.6.1. Company Overview
    • 9.6.2. Financial Information
    • 9.6.3. Service Portfolio
    • 9.6.4. Product Portfolio
    • 9.6.5. Recent Developments and Future Outlook

10. SINGLE-USE UPSTREAM BIOPROCESSING TECHNOLOGY PROVIDERS IN EUROPE: COMPANY PROFILES

  • 10.1. Chapter Overview
  • 10.2. Eppendorf
    • 10.2.1. Company Overview
    • 10.2.2. Financial Information
    • 10.2.3. Service Portfolio
    • 10.2.4. Product Portfolio
    • 10.2.5. Recent Developments and Future Outlook
  • 10.3. Saint-Gobain
    • 10.3.1. Company Overview
    • 10.3.2. Financial Information
    • 10.3.3. Service Portfolio
    • 10.3.4. Product Portfolio
    • 10.3.5. Recent Developments and Future Outlook
  • 10.4. Sartorius
    • 10.4.1. Company Overview
    • 10.4.2. Financial Information
    • 10.4.3. Service Portfolio
    • 10.4.4. Product Portfolio
    • 10.4.5. Recent Developments and Future Outlook

11. SINGLE-USE UPSTREAM BIOPROCESSING TECHNOLOGY PROVIDERS IN ASIA-PACIFIC: COMPANY PROFILES

  • 11.1. Chapter Overview
  • 11.2. Satake Multimix
    • 11.2.1. Company Overview
    • 11.2.2. Financial Information
    • 11.2.3. Service Portfolio
    • 11.2.4. Product Portfolio
    • 11.2.5. Recent Developments and Future Outlook
  • 11.3. REPROCELL
    • 11.3.1. Company Overview
    • 11.3.2. Financial Information
    • 11.3.3. Service Portfolio
    • 11.3.4. Product Portfolio
    • 11.3.5. Recent Developments and Future Outlook
  • 11.4. Premas Biotech
    • 11.4.1. Company Overview
    • 11.4.2. Financial Information
    • 11.4.3. Service Portfolio
    • 11.4.4. Product Portfolio
    • 11.4.5. Recent Developments and Future Outlook

12. PATENT ANALYSIS

  • 12.1. Chapter Overview
  • 12.2. Scope and Methodology
  • 12.3. Single-use Upstream Bioprocessing Technology: Patent Analysis
    • 12.3.1. Analysis by Publication Year
    • 12.3.2. Analysis by Application Year
    • 12.3.3. Analysis by Patent Office
    • 12.3.4. Analysis by Geographical Location
    • 12.3.5. Analysis by CPC Symbols
    • 12.3.6. Emerging Focus Area
    • 12.3.7. Analysis by Type of Organization
    • 12.3.8. Leading Players: Analysis by Number of Patents
  • 12.4. Patent Benchmarking Analysis
    • 12.4.1. Analysis by Patent Characteristics
  • 12.5. Analysis by Patent Valuation

13. BRAND POSITIONING MATRIX

  • 13.1. Chapter Overview
  • 13.2 Methodology
  • 13.3. Key Parameters
  • 13.4. Brand Positioning Matrix of Single-use Bioreactor Developers
    • 13.4.1. Brand Positioning Matrix: Pall Corporation
    • 13.4.2. Brand Positioning Matrix: Eppendorf
    • 13.4.3. Brand Positioning Matrix: Solaris Biotech
    • 13.4.4. Brand Positioning Matrix: Sartorius Stedim Biotech
    • 13.4.5. Brand Positioning Matrix: Applikon Biotechnology
    • 13.4.6. Brand Positioning Matrix: CerCell
    • 13.4.7. Brand Positioning Matrix: Synthecon
  • 13.5. Brand Positioning Matrix of Single-use Mixer Developers
    • 13.5.1. Brand Positioning Matrix: Thermo Fisher Scientific
    • 13.5.2. Brand Positioning Matrix: Merck Millipore
    • 13.5.3. Brand Positioning Matrix: Cytiva Lifesciences
    • 13.5.4. Brand Positioning Matrix: Pall Corporation
  • 13.6. Brand Positioning Matrix of Single-use Sensors Developers
    • 13.6.1. Brand Positioning Matrix: Masterflex
    • 13.6.2. Brand Positioning Matrix: Levitronix
    • 13.6.3. Brand Positioning Matrix: Malema Engineering
    • 13.6.4. Brand Positioning Matrix: Parken Hannifin
    • 13.6.5. Brand Positioning Matrix: Pendo TECH

14. CASE STUDY: COST AND TIME SAVING POTENTIAL OF SINGLE-USE UPSTREAM BIOPROCESSING TECHNOLOGY

  • 14.1. Chapter Overview
  • 14.2. Overall Cost Saving Potential of Single-Use Upstream Bioprocessing Technology, 2022-2035
    • 14.2.1. Scenario 1
      • 14.2.1.1. Key Assumptions and Methodology
      • 14.2.1.2. Cost Saving Potential with Acquisition of Single-Use Upstream Technology, 2022-2035
    • 14.2.2. Scenario 2
      • 14.2.2.1. Key Assumptions and Methodology
      • 14.2.2.2. Cost Saving Potential with Implementation of Single-Use Upstream Bioprocessing Technology, 2022-2035
  • 14.3. Overall Time Saving Potential of Single-Use Upstream Bioprocessing Technology, 2022-2035
  • 14.4. Concluding Remarks

15. DEMAND AND SUPPLY ANALYSIS

  • 15.1. Chapter Overview
  • 15.2. Key Assumptions and Methodology
  • 15.3. Global Demand for Biologics, 2022-2035
    • 15.3.1. Demand Vs Supply Scenario 1
    • 15.3.2. Demand Vs Supply Scenario 2
    • 15.3.3. Demand Vs Supply Scenario 3
    • 15.3.4. Demand Vs Supply Scenario 4
  • 15.4. Concluding Remarks

16. MARKET FORECAST AND OPPORTUNITY ANALYSIS

  • 16.1. Chapter Overview
  • 16.2. Forecast Methodology and Key Assumptions
  • 16.3. Global Single-use Upstream Bioprocessing Technology Market, 2022-2035
    • 16.3.1. Global Single-use Upstream Bioprocessing Technology Market, 2022-2035: Distribution by Scale of Operation
      • 16.3.1.1. Global Single-use Upstream Bioprocessing Technology Market for Preclinical / Clinical Operations, 2022-2035
      • 16.3.1.2. Global Single-use Upstream Bioprocessing Technology Market for Commercial Operations, 2022-2035
    • 16.3.2. Global Single-use Upstream Bioprocessing Technology Market, 2022-2035: Distribution by Type of Equipment
      • 16.3.2.1. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Bioreactors, 2022-2035
      • 16.3.2.2. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Mixers, 2022-2035
      • 16.3.2.3. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Media Bags, 2022-2035
      • 16.3.2.4. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Filters, 2022-2035
      • 16.3.2.5. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Sampling Systems, 2022-2035
      • 16.3.2.6. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Connectors, 2022-2035
      • 16.3.2.7. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Membrane Adsorbers, 2022-2035
      • 16.3.2.8. Global Single-use Upstream Bioprocessing Technology Market for Other Single-Use Technologies, 2022-2035
    • 16.3.3. Global Single-use Upstream Bioprocessing Technology Market, 2022-2035: Distribution by Geographical Region
      • 16.3.3.1. Global Single-use Upstream Bioprocessing Technology Market in North America, 2022-2035
        • 16.3.2.1.1. Global Single-use Upstream Bioprocessing Technology Market for Single- Use Bioreactors in North America, 2022-2035
        • 16.3.2.1.2. Global Single-use Upstream Bioprocessing Technology Market for Single- Use Mixers in North America, 2022-2035
        • 16.3.2.1.3. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Media Bags in North America, 2022-2035
        • 16.3.2.1.4. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Filters in North America, 2022-2035
        • 16.3.2.1.5. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Sampling Systems in North America, 2022-2035
        • 16.3.2.1.6. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Connectors in North America, 2022-2035
        • 16.3.2.1.7. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Membrane Adsorbers in North America, 2022-2035
        • 16.3.2.1.8. Global Single-use Upstream Bioprocessing Technology Market for Other Single-Use Technologies in North America, 2022-2035
      • 16.3.3.2. Global Single-use Upstream Bioprocessing Technology Market in Europe, 2022-2035
        • 16.3.2.2.1. Global Single-use Upstream Bioprocessing Technology Market for Single- Use Bioreactors in Europe, 2022-2035
        • 16.3.2.2.2. Global Single-use Upstream Bioprocessing Technology Market for Single- Use Mixers in Europe, 2022-2035
        • 16.3.2.2.3. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Media Bags in Europe, 2022-2035
        • 16.3.2.2.4. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Filters in Europe, 2022-2035
        • 16.3.2.2.5. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Sampling Systems in Europe, 2022-2035
        • 16.3.2.2.6. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Connectors in Europe, 2022-2035
        • 16.3.2.2.7. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Membrane Adsorbers in Europe, 2022-2035
        • 16.3.2.2.8. Global Single-use Upstream Bioprocessing Technology Market for Other Single-Use Technologies in Europe, 2022-2035
      • 16.3.3.3. Global Single-use Upstream Bioprocessing Technology Market in Asia-Pacific, 2022-2035
        • 16.3.2.3.1. Global Single-use Upstream Bioprocessing Technology Market for Single- Use Bioreactors in Asia-Pacific, 2022-2035
        • 16.3.2.3.2. Global Single-use Upstream Bioprocessing Technology Market for Single- Use Mixers in Asia-Pacific, 2022-2035
        • 16.3.2.3.3. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Media Bags in Asia-Pacific, 2022-2035
        • 16.3.2.3.4. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Filters in Asia-Pacific, 2022-2035
        • 16.3.2.3.5. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Sampling Systems in Asia-Pacific, 2022-2035
        • 16.3.2.3.6. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Connectors in Asia-Pacific, 2022-2035
        • 16.3.2.3.7. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Membrane Adsorbers in Asia-Pacific, 2022-2035
        • 16.3.2.3.8. Global Single-use Upstream Bioprocessing Technology Market for Other Single-Use Technologies in Asia-Pacific, 2022-2035
      • 16.3.3.4. Global Single-use Upstream Bioprocessing Technology Market in Latin America, 2022-2035
        • 16.3.2.4.1. Global Single-use Upstream Bioprocessing Technology Market for Single- Use Bioreactors in Latin America, 2022-2035
        • 16.3.2.4.2. Global Single-use Upstream Bioprocessing Technology Market for Single- Use Mixers in Latin America, 2022-2035
        • 16.3.2.4.3. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Media Bags in Latin America, 2022-2035
        • 16.3.2.4.4. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Filters in Latin America, 2022-2035
        • 16.3.2.4.5. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Sampling Systems in Latin America, 2022-2035
        • 16.3.2.4.6. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Connectors in Latin America, 2022-2035
        • 16.3.2.4.7. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Membrane Adsorbers in Latin America, 2022-2035
        • 16.3.2.4.8. Global Single-use Upstream Bioprocessing Technology Market for Other Single-Use Technologies in Latin America, 2022-2035
      • 16.3.3.5. Global Single-Use Upstream Bioprocessing Technology Market in Middle East and North Africa, 2022-2035
        • 16.3.2.5.1. Global Single-use Upstream Bioprocessing Technology Market for Single- Use Bioreactors in Middle East and North Africa, 2022-2035
        • 16.3.2.5.2. Global Single-use Upstream Bioprocessing Technology Market for Single- Use Mixers in Middle East and North Africa, 2022-2035
        • 16.3.2.5.3. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Media Bags in Middle East and North Africa, 2022-2035
        • 16.3.2.5.4. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Filters in Middle East and North Africa, 2022-2035
        • 16.3.2.5.5. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Sampling Systems in Middle East and North Africa, 2022-2035
        • 16.3.2.5.6. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Connectors in Middle East and North Africa, 2022-2035
        • 16.3.2.5.7. Global Single-use Upstream Bioprocessing Technology Market for Single-Use Membrane Adsorbers in Middle East and North Africa, 2022-2035
        • 16.3.2.5.8. Global Single-use Upstream Bioprocessing Technology Market for Other Single-Use Technologies in Middle East and North Africa, 2022-2035

17. CONCLUSION

  • 17.1. Chapter Overview

18. EXECUTIVE INSIGHTS

  • 18.1. Chapter Overview
  • 18.2. Celltainer Biotech
    • 18.2.1. Company Snapshot
    • 18.2.2. Interview Transcript: Nico Oosterhuis, Technical Director and Co-Owner
  • 18.3. Thermo Fisher Scientific
    • 18.3.1. Company Snapshot
    • 18.3.2. Interview Transcript: Christopher Brau, R&D Staff Scientist and Engineer

19. APPENDIX 1: TABULATED DATA

20. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS

List Of Figures

  • Figure 4.1. Single-use Bioreactors: Distribution by Type of Bioreactor
  • Figure 4.2. Single-use Bioreactors: Distribution by Scale of Operation
  • Figure 4.3. Single-use Bioreactors: Distribution by Type of Cell Culture System
  • Figure 4.4. Single-use Bioreactors: Distribution by Type of Cell Culture
  • Figure 4.5. Single-use Bioreactors: Distribution by Type of Molecule Processed
  • Figure 4.6. Single-use Bioreactors: Distribution by Key Features
  • Figure 4.7. Single-use Bioreactors: Distribution by Application Area
  • Figure 4.8. Single-use Bioreactors: Distribution by End Users
  • Figure 4.9. Single-use Bioreactors: Distribution of Developers by Year of Establishment
  • Figure 4.10. Single-use Bioreactors: Distribution of Developers by Company Size
  • Figure 4.11. Single-use Bioreactors: Distribution of Developers by Leading Players
  • Figure 4.12. Single-use Bioreactors: Distribution of Developers by Location of Headquarters
  • Figure 5.1. Single-use Mixers: Distribution by Scale of Operation
  • Figure 5.2. Single-use Mixers: Distribution by Type of Mixing System
  • Figure 5.3. Single-use Mixers: Distribution by Type of Molecule Processed
  • Figure 5.4. Single-use Mixers: Distribution by Key Features
  • Figure 5.5. Single-use Mixers: Distribution by Application Area
  • Figure 5.6. Single-use Mixers: Distribution of Developers by Year of Establishment
  • Figure 5.7. Single-use Mixers: Distribution of Developers by Company Size
  • Figure 5.8. Single-use Mixers: Distribution of Developers by Geographical Region
  • Figure 5.9. Single-use Mixers: Distribution of Developers by Year of Establishment and Company Size
  • Figure 5.10. Single-use Mixers: Distribution of Developers by Leading Players
  • Figure 6.1. Single-use Sensors: Distribution by Type of Sensor
  • Figure 6.2. Single-use Sensors: Distribution by Type of Sensor Calibration
  • Figure 6.3. Single-use Sensors: Distribution by Sterilization Techniques
  • Figure 6.4. Single-use Sensors: Distribution by Application Area
  • Figure 6.5. Single-use Sensors: Distribution by Material of Construction
  • Figure 6.6. Single-use Sensors: Distribution of Developers by Year of Establishment
  • Figure 6.7. Single-use Sensors: Distribution of Developers by Company Size
  • Figure 6.8. Single-use Sensors: Distribution of Developers by Geographical Region
  • Figure 8.1. Product Competitiveness Analysis: Single-use Bioreactor developers based in North America
  • Figure 8.2. Product Competitiveness Analysis: Single-use Bioreactor developers based in Europe (Scoring range from 1-12 on X-axis)
  • Figure 8.3. Product Competitiveness Analysis: Single-use Bioreactor developers based in Asia-Pacific
  • Figure 8.4. Product Competitiveness Analysis: Single-use Mixer developers based in North America
  • Figure 8.5. Product Competitiveness Analysis: Single-use Mixer developers based in Europe
  • Figure 8.6. Product Competitiveness Analysis: Single-use Sensor developers based in North America
  • Figure 8.7. Product Competitiveness Analysis: Single-use Sensor developers based in Europe
  • Figure 9.1. Avantor: Annual Revenues, 2016- 9M 2021 (USD Billion)
  • Figure 9.2. Cytiva: Annual Revenues, 2016- 9M 2021 (USD Billion)
  • Figure 9.3. Merck KGaA: Annual Revenues, 2017- 9M 2021 (USD Billion)
  • Figure 9.4. Thermo Fisher Scientific: Annual Revenues, 2016- 9M 2021 (USD Billion)
  • Figure 10.1. Eppendorf: Annual Revenues, 2016- 2020 (EUR Billion)
  • Figure 10.2. Saint-Gobain: Annual Revenues, 2016- 9M 2021 (EUR Billion)
  • Figure 10.3. Sartorius: Annual Revenues, 2016- 9M 2021 (EUR Billion)
  • Figure 12.1. Patent Analysis: Cumulative Distribution by Publication Year
  • Figure 12.2. Patent Analysis: Distribution by Type of Patents
  • Figure 12.3. Patent Analysis: Geographical Distribution by Issuing Authority
  • Figure 12.4. Patent Analysis: Cumulative Year wise trend of Patents
  • Figure 12.5. Patent Analysis: Distribution by Type of Organization
  • Figure 12.6. Patent Analysis: Distribution by Patent Age
  • Figure 12.7. Patent Analysis: Distribution by Patent Valuation
  • Figure 12.8. Patent Analysis: Distribution by Most Popular CPC Symbol
  • Figure 12.9. Patent Analysis: Leading Industry Players
  • Figure 12.10. Patent Analysis: Leading Academic Players
  • Figure 12.11. Patent Analysis: Leading Patent Assignees
  • Figure 13.1. Brand Positioning Matrix of Single-use Bioreactors: Pall
  • Figure 13.2. Brand Positioning Matrix of Single-use Bioreactors: Eppendorf
  • Figure 13.3. Brand Positioning Matrix of Single-use Bioreactors: Solaris Biotech
  • Figure 13.4. Brand Positioning Matrix of Single-use Bioreactors: Sartorius Stedim Biotech
  • Figure 13.5. Brand Positioning Matrix of Single-use Bioreactors: Applikon Biotechnology
  • Figure 13.6. Brand Positioning Matrix of Single-use Bioreactors: CerCell
  • Figure 13.7. Brand Positioning Matrix of Single-use Bioreactors: Sythecon
  • Figure 13.8. Brand Positioning Matrix of Single-use Mixers: Thermo Fisher Scientific
  • Figure 13.9. Brand Positioning Matrix of Single-use Mixers: Merck Millipore
  • Figure 13.10. Brand Positioning Matrix of Single-use Mixers: Cytiva
  • Figure 13.11. Brand Positioning Matrix of Single-use Mixers: Pall
  • Figure 13.12. Brand Positioning Matrix of Single-use Sensors: Masterflex
  • Figure 13.13. Brand Positioning Matrix of Single-use Sensors: Levitronix
  • Figure 13.14. Brand Positioning Matrix of Single-use Sensors: Malema Engineering
  • Figure 13.15. Brand Positioning Matrix of Single-use Sensors: Parken Hannif
  • Figure 13.16. Brand Positioning Matrix of Single-use Sensors: Pendo TECH
  • Figure 14.1. Cost Saving Analysis (Equipment Cost)
  • Figure 14.2. Cost Saving Analysis (Manufacturing Cost)
  • Figure 15.1. Demand and Supply Analysis: Demand for Biologics, 2022-2035
  • Figure 15.2. Demand and Supply Analysis: Demand and Supply, 2022-2035
  • Figure 16.1. Single-use Upstream Bioprocessing Technology Market, 2022-2035: Distribution by Scale of Operation
  • Figure 16.2. Single-use Upstream Bioprocessing Technology Market, 2022-2035: Distribution by Type of Equipment
  • Figure 16.3. Single-use Upstream Bioprocessing Technology Market for Single-use Filters, 2022-2035
  • Figure 16.4. Single-use Upstream Bioprocessing Technology Market for Single-use Media Bags, 2022-2035
  • Figure 16.5. Single-use Upstream Bioprocessing Technology Market for Single-use Bioreactors, 2022-2035
  • Figure 16.6. Single-use Upstream Bioprocessing Technology Market for Single-use Mixers, 2022-2035
  • Figure 16.7. Single-use Upstream Bioprocessing Technology Market for Single-use Connectors, 2022-2035
  • Figure 16.8. Single-use Upstream Bioprocessing Technology Market for Single-use Sampling Systems, 2022-2035
  • Figure 16.9. Single-use Upstream Bioprocessing Technology Market for Single-use Membrane Adsorbents, 2022-2035
  • Figure 16.10. Single-use Upstream Bioprocessing Technology Market for Other Single-use Technology, 2022-2035
  • Figure 16.11. Single-use Upstream Bioprocessing Technology Market, 2022-2035: Distribution by Geography
  • Figure 16.12. Single-use Upstream Bioprocessing Technology Market, 2022-2035: Distribution by Geography
  • Figure 16.13. Single-use Upstream Bioprocessing Technology Market in North America, 2022-2035
  • Figure 16.14. Single-use Upstream Bioprocessing Technology Market in North America, 2022-2035: Distribution by Type of Equipment
  • Figure 16.15. Single-use Upstream Bioprocessing Technology Market in Europe, 2022-2035
  • Figure 16.16. Single-use Upstream Bioprocessing Technology Market in Europe, 2022-2035: Distribution by Type of Equipment
  • Figure 16.17. Single-use Upstream Bioprocessing Technology Market in Asia-Pacific, 2022-2035
  • Figure 16.18. Single-use Upstream Bioprocessing Technology Market, 2022-2035 in Asia-Pacific: Distribution by Type of Equipment
  • Figure 16.19. Single-use Upstream Bioprocessing Technology Market in Latin America, 2022-2035
  • Figure 16.20. Single-use Upstream Bioprocessing Technology Market in Latin America, 2022-2035: Distribution by Type of Equipment
  • Figure 16.21. Single-use Upstream Bioprocessing Technology Market in Middle East and North Africa, 2022-2035
  • Figure 16.22. Single-use Upstream Bioprocessing Technology Market in Middle East and North Africa, 2022-2035: Distribution by Type of Equipment

List Of Tables

  • Table 4.1. Single-use Bioreactors: Information on Developers, Scale of Operation, Key Features, Type of Cell Culture System, Type of Cell Culture, Type of Molecule and Application Areas
  • Table 5.1. Single-use Mixers: Information on Developers, Scale of Operation, Type of Mixing System, Type of Molecule used, Key Features and Application Areas
  • Table 6.1. Single-use Sensors: Information on Developers, Product Specific Details, Type of Bioprocessing, Sterilization Techniques used and Application Areas
  • Table 7.1. Single-use Media Bags and Containers: Information on Developers, Purpose of Product, Type of Material / Tubing used, Key Features and Application Areas
  • Table 7.2. Single-use Filters: Information on Developers, Material of Construction, Key Features and Application Areas
  • Table 7.3. Single-use Connectors: Information on Developers, Material of Construction, Gender / Valve, Sterilizability, Key Features and Application Areas
  • Table 7.4. Single-use Sampling Systems: Information on Developers, Tubing Material, Sampling Unit, Sterilizability, Key Features and Application Areas
  • Table 9.1. Avantor: Product Portfolio (Single-use Bags and Containers)
  • Table 9.2. Avantor: Product Portfolio (Single-use Mixers)
  • Table 9.3. Cytiva: Product Portfolio (Single-use Bioreactors)
  • Table 9.4. Cytiva: Product Portfolio (Single-use Mixers)
  • Table 9.5. Merck KGaA: Product Portfolio (Single-use Bioreactors)
  • Table 9.6. Merck KGaA: Product Portfolio (Single-use Mixers)
  • Table 9.7. Merck KGaA: Product Portfolio (Single-use Filters)
  • Table 9.8. Pall: Product Portfolio (Single-use Bioreactors)
  • Table 9.9. Pall: Product Portfolio (Single-use Media Bags and Containers)
  • Table 9.10. Pall: Product Portfolio (Single-use Mixers)
  • Table 9.11. Thermo Fisher Scientific: Product Portfolio (Single-use Media Bags and Containers)
  • Table 9.12. Thermo Fisher Scientific: Product Portfolio (Single-use Mixers)
  • Table 10.1. Eppendorf: Product Portfolio (Single-use Bioreactors)
  • Table 10.2. Saint Gobain: Product Portfolio (Single-use Media Bags and Containers)
  • Table 10.3. Sartorius: Product Portfolio (Single-use Media Bags and Containers)
  • Table 11.1. Satake Multimix: Product Portfolio (Single-use Bioreactors)
  • Table 11.2. Reprocell: Product Portfolio (Single-use Bioreactors)
  • Table 11.3. Premas Biotech: Product Portfolio (Single-use Bioreactors)

List Of Companies

The following companies / institutes / government bodies and organizations have been mentioned in this report.

  • 1. 3M
  • 2. ABEC
  • 3. Acceleron Pharma
  • 4. Applied Biosensors
  • 5. Applikon Biotechnology
  • 6. Avantor
  • 7. BIONET
  • 8. Bioprocess Engineering Services (BPES)
  • 9. Biosan
  • 10. Celartia
  • 11. Cell Culture Company
  • 12. CellBios Healthcare & Lifesciences
  • 13. Cellexus
  • 14. Celltainer Biotech
  • 15. CerCell
  • 16. CESCO Bioengineering
  • 17. Corning
  • 18. Cytiva
  • 19. Distek
  • 20. DrM Life Science
  • 21. Emerson
  • 22. Entegris
  • 23. Eppendorf
  • 24. Equflow
  • 25. ErtelAlsop
  • 26. Esco Aster
  • 27. Finesse Solutions
  • 28. FlexBiosys
  • 29. High Purity New England
  • 30. INTEGRA Biosciences
  • 31. LFB Biomanufacturing
  • 32. Malema Engineering
  • 33. Masterflex
  • 34. Meissner Filtration Products
  • 35. Merck KGaA
  • 36. METTLER TOLEDO
  • 37. MicroDigital
  • 38. OmniBRx Biotechnologies
  • 39. optek-Danulat
  • 40. Pall Corporation
  • 41. Parker Hannifin
  • 42. PBS Biotech
  • 43. PerfuseCell
  • 44. Polestar Technologies
  • 45. PPD
  • 46. Premas Biotech
  • 47. PreSens Precision Sensing
  • 48. ProlifeCell
  • 49. RealBio Technology
  • 50. Rentschler Biopharma
  • 51. REPROCELL
  • 52. RIM Bio
  • 53. Saint-Gobain
  • 54. Sartorius Stedim Biotech
  • 55. SATAKE MultiMix
  • 56. Scinus Cell Expansion
  • 57. Sensirion
  • 58. Sentinel Process Systems
  • 59. Solaris Biotech
  • 60. Solida Biotech
  • 61. Strain Measurement Devices
  • 62. Synthecon
  • 63. Thermo Fisher Scientific
  • 64. Univercells
  • 65. Venair
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