Global Protein Crystallization Market: Current Analysis and Forecast (2022-2028)

Protein crystallization is the process of obtaining a protein crystal by the addition of precipitating agents and controlling the conditions, such as temperature, ionic strength, and pH of the solution. Protein crystallization is an important process in the formation of monoclonal antibodies and the formation of drugs. The rising number of infectious diseases and increased efforts in the development of therapeutic drugs for the treatment of diseases attributes to the growth of the protein crystallization market. Furthermore, the rising efforts in the development of novel drugs along with the increasing research and development investments attributes to the market growth of protein crystallization.

The Protein Crystallization Market is expected to grow at a steady rate of around 8% owing to the increasing prevalence of chronic diseases. For instance, as per the CDC, in 2020, about 697,000 people in the United States died from heart disease.

Based on the type, the market has been categorized into consumables, reagent kits, instruments, and software and services. Among them, the reagent kits segment is expected to grow at a higher CAGR in the market. The reagents have various applications in the biochemistry of proteins such as precipitating agents, detergents, or additives. These factors are responsible for the significant growth of the reagent kit segment during the forecast period.

Based on the technology, the market has been categorized into x-ray crystallography, NMR spectroscopy, cryo-electron microscopy, and small-angle x-ray scattering (SAXS). Among them, the x-ray crystallography segment holds considerable growth in the market, and it is expected to grow at a significant CAGR during the forecast period. X-ray Crystallography is a scientific method used to determine the arrangement of atoms of a crystalline solid in three-dimensional space. Frequent product launches and advancements in x-ray diffraction technology attributes to the growth of the segment in the protein crystallization market. For instance, in November 2020, Rigaku Corporation announced the release of the Rigaku HyPix-Arc 100° curved photon counting (HPC) X-ray detector for single crystal X-ray diffraction applications.

Based on the end-user, the market has been categorized into pharmaceutical companies, biotechnology companies, and others. Among them, the biotechnology segment is expected to grow at a significant CAGR during the forecast period. The rising demand for the biopharmaceutical products such as vaccines, and other medications attributes to the growth of the segment. Furthermore, increasing research efforts in the development of protein-based biosimilars along with the rising awareness of biotechnological products attributes to the significant growth of biotechnology companies.

For a better understanding of the market adoption of the protein crystallization industry, the market is analyzed based on its worldwide presence in the countries such as North America (United States, Canada, and the Rest of North America), Europe (Germany, France, Italy, Spain, United Kingdom, and Rest of Europe), Asia-Pacific (China, Japan, India, Australia, and Rest of APAC), and Rest of World. In 2020, North America held a dominant share in the market. The major factors such as the presence of major economies such as the United States in the region are attributed to the presence of market players in the region. Furthermore, the higher adoption of advanced technology and increasing efforts on R&D in the region also attributes to the market growth of the protein crystallization market in North America. In March 2021, the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and colleagues at Columbia University developed a new approach for solving protein structures from tiny crystals.

Some of the major players operating in the market are Rigaku Corporation, Hampton Research Corp, HiMedia Laboratories, Bruker, Thermo Fisher Scientific, Jena Bioscience GmbH, Agilent Technologies Inc., Charles River Laboratories, Molecular Dimensions, and Formulatrix.