T-Cell therapy Market By Therapy Type (CAR T-Cell therapy, T-Cell Receptor -Based), By Indication, By End User : Global Opportunity Analysis and Industry Forecast, 2023-2032

Description

List of Tables

According to a new report published by Allied Market Research, titled, "T-Cell therapy Market," The t-cell therapy market was valued at $2.8 billion in 2022, and is estimated to reach $15.2 billion by 2032, growing at a CAGR of 18.3% from 2023 to 2032.

The T-Cell therapy market was negatively impacted during the lockdown period owing to a disrupted global supply chain, which had affected the production and distribution of T-cell therapies. Moreover, post COVID-19 prevailing cases of cancer has highlighted the need for innovation in the healthcare sector and thus shown positive impact on the growth of the market.

Market dynamics

The rise in cancer prevalence, rise in geriatric population, and rise in the use of various cell therapy technologies to treat the symptoms of cancer are the main drivers propelling the growth of the T-cell therapy market size. Leukemia, myeloma, lymphoma, and cancer relapse are among the cancers that are becoming more common, which increases the demand for effective therapeutic treatments and propels the market's expansion. For instance, according to National Library of Medicine in China 2022, is estimated the approximately 88,249 new cases of leukemia (50,213 male cases and 38,036 female cases). In addition, increase in number of clinical trials and increase in public and private investments for the development of cell therapy technology in which T cells are collected from a patient are genetically modified ex vivo and re-injected into the patient drive the T-cell therapy market growth.

Moreover, the T-cell therapy market is characterized by continuous evolution and growth, primarily fueled by ongoing research and development efforts. The field of T-cell therapy is dynamic, with scientists and researchers exploring novel approaches, technologies, and therapeutic targets to enhance the effectiveness and broaden the applications of T-cell therapies.

In addition, the presence of multiple drugs in the clinical development phase is also driving the market growth. For instance, CB-010 and CB-011 of Caribou Biosciences, Inc are in clinical phase I trials. Similarly, DESCARTES-17 and DESCARTES-25 of Cartesian Therapeutics, Inc. are in preclinical and Phase I trials respectively. Thus, the focus of key players on developments is further anticipated to potentially drive the growth during T-cell therapy market forecast.

Furthermore, the growing demand for effective therapeutic solutions is not only limited to developed countries but is also being witnessed in the developing countries, such as China, Brazil, and India, which fuel the growth of the market. Moreover, an increase in promotional activities by manufacturers and growth in awareness for proper treatment medications for cancer among the general population are expected to fuel their adoption during the forecast period.

However, the market growth of T-cell therapy is hindered by several factors including the high cost associated with T-cell therapy. It poses a barrier to its widespread adoption and limiting patient access. Furthermore, stringent government regulations and lengthy approval processes create delays in introducing T-cell therapies to the market, affecting their availability. In addition, the guidelines that restrict the use of T-cell therapy as a later line of treatment after chemotherapy failure limit its potential impact and delay its application in earlier stages of disease. These factors collectively impede the market growth of T-cell therapy, necessitating efforts to address cost concerns, streamline regulatory processes, and explore its utilization in earlier treatment settings.

The outbreak of COVID-19 has disrupted workflows in the health care sector around the world including the T-cell therapy market. The T-cell therapy market is negatively impacted by the pandemic as most countries adopted lockdown. Some companies experienced delays in the manufacture and delivery of T-cell therapies due to supply chain disruptions.

Additionally, many clinical trials of T-cell therapies had been disrupted due to the COVID-19 pandemic, with some trials being delayed or suspended altogether. This has slowed down the development and approval of new T-cell therapies. For instance, according to a Cancer Research Institute and IQVIA survey published in Nature Reviews Drug Discovery, found that patient enrollment in oncology clinical trials during the early stages of the pandemic was significantly impacted in the U.S and Europe, where 60% and 86% of institutions respectively were enrolling new patients at a lower rate. The main obstacles to enrollment in trials were access, concerns over patients' risk of contracting the virus. Thus, decline in people transit, closing of borders, and confinement of the population impacted the supply chains of these life-saving medical therapies and had a negative impact on the growth of T-cell therapy industry.

However, post pandemic it was observed that the prevailing cases of cancer have highlighted the need for innovation in the healthcare sector, and many companies are increasing their investments in research and development. Furthermore, the increasing approvals by regulatory agencies have further driven the opportunity for the key players. For instance, in November 2022, Caribou Biosciences, Inc., a leading clinical-stage CRISPR genome-editing biopharmaceutical company, received clearance for its Investigational New Drug (IND) application from the U.S. Food and Drug Administration (FDA) for CB-011, a genome-edited allogeneic anti-BCMA CAR-T cell therapy with immune cloaking. Thus, the increasing cases, growing demand for ideal therapeutics, and presence of multiple promising drugs in pipeline are expected to drive the market during the forecast years.

Segmental Overview

The global T-cell therapy market is segmented into therapy type, indication, end user and region. As per therapy type, the market is categorized into CAR T-cell Therapy and T Cell Receptor (TCR)-Based. The CAR T-cell Therapy segment is further categorized by product type into Axicabtagene Ciloleucel, Tisagenlecleucel, Bexucabtagene Autoleucel and Others (Ciltacabtagene autoleucel, Lisocabtagene Maraleucel, Idecabtagene Vicleucel). According to indication, the market is segregated into Lymphoma, Acute Lymphocytic Leukemia, and Others (Multiple Myeloma, Melanoma). According to end user, the market is segregated into Hospitals and Cancer Treatment Centers. Region wise, the market is analyzed across North America (the U.S., Canada), Europe (Germany, France, the UK, and rest of Europe), Asia-Pacific (Japan, China and rest of Asia-Pacific), and LAMEA (Latin America, Middle East & Africa).

Key Benefits For Stakeholders:

This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the t-cell therapy market analysis from 2022 to 2032 to identify the prevailing t-cell therapy market opportunity.

The market research is offered along with information related to key drivers, restraints, and opportunities.

Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.

In-depth analysis of the t-cell therapy market segmentation assists to determine the prevailing market opportunities.

Major countries in each region are mapped according to their revenue contribution to the global market.

Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.

The report includes the analysis of the regional as well as global t-cell therapy market trends, key players, market segments, application areas, and market growth strategies.

Product Code: A10528

CHAPTER 1: INTRODUCTION

1.1. Report description
1.2. Key market segments
1.3. Key benefits to the stakeholders
1.4. Research Methodology
- 1.4.1. Primary research
- 1.4.2. Secondary research
- 1.4.3. Analyst tools and models

CHAPTER 2: EXECUTIVE SUMMARY

2.1. CXO Perspective

CHAPTER 3: MARKET OVERVIEW

3.1. Market definition and scope
3.2. Key findings
- 3.2.1. Top impacting factors
- 3.2.2. Top investment pockets
3.3. Porter's five forces analysis
- 3.3.1. Bargaining power of suppliers
- 3.3.2. Bargaining power of buyers
- 3.3.3. Threat of substitutes
- 3.3.4. Threat of new entrants
- 3.3.5. Intensity of rivalry
3.4. Market dynamics
- 3.4.1. Drivers
  - 3.4.1.1. Rise in prevalence of cancer
  - 3.4.1.2. Increase in demand of ideal therapeutics for treatment
  - 3.4.1.3. Rise in awareness regarding T-cell therapy

3.4.2. Restraints
- 3.4.2.1. High cost of T-cell therapies
- 3.4.2.2. Strict government regulation for approval of drugs

3.4.3. Opportunities
- 3.4.3.1. Increase in R&D activities to develop T-cell therapeutics

3.5. COVID-19 Impact Analysis on the market

CHAPTER 4: T-CELL THERAPY MARKET, BY THERAPY TYPE

4.1. Overview
- 4.1.1. Market size and forecast
4.2. CAR T-Cell therapy
- 4.2.1. Key market trends, growth factors and opportunities
- 4.2.2. Market size and forecast, by region
- 4.2.3. Market share analysis by country
- 4.2.4. CAR T-Cell therapy T-Cell therapy Market by Product Type
4.3. T-Cell Receptor (TCR)-Based
- 4.3.1. Key market trends, growth factors and opportunities
- 4.3.2. Market size and forecast, by region
- 4.3.3. Market share analysis by country

CHAPTER 5: T-CELL THERAPY MARKET, BY INDICATION

5.1. Overview
- 5.1.1. Market size and forecast
5.2. Lymphoma
- 5.2.1. Key market trends, growth factors and opportunities
- 5.2.2. Market size and forecast, by region
- 5.2.3. Market share analysis by country
5.3. Acute Lymphocytic Leukemia
- 5.3.1. Key market trends, growth factors and opportunities
- 5.3.2. Market size and forecast, by region
- 5.3.3. Market share analysis by country
5.4. Others
- 5.4.1. Key market trends, growth factors and opportunities
- 5.4.2. Market size and forecast, by region
- 5.4.3. Market share analysis by country

CHAPTER 6: T-CELL THERAPY MARKET, BY END USER

6.1. Overview
- 6.1.1. Market size and forecast
6.2. Hospitals
- 6.2.1. Key market trends, growth factors and opportunities
- 6.2.2. Market size and forecast, by region
- 6.2.3. Market share analysis by country
6.3. Cancer Treatment Centers
- 6.3.1. Key market trends, growth factors and opportunities
- 6.3.2. Market size and forecast, by region
- 6.3.3. Market share analysis by country

CHAPTER 7: T-CELL THERAPY MARKET, BY REGION

7.1. Overview
- 7.1.1. Market size and forecast By Region
7.2. North America
- 7.2.1. Key trends and opportunities
- 7.2.2. Market size and forecast, by Therapy Type
- 7.2.3. Market size and forecast, by Indication
- 7.2.4. Market size and forecast, by End User
- 7.2.5. Market size and forecast, by country
  - 7.2.5.1. U.S.
  - 7.2.5.1.1. Key market trends, growth factors and opportunities
  - 7.2.5.1.2. Market size and forecast, by Therapy Type
  - 7.2.5.1.3. Market size and forecast, by Indication
  - 7.2.5.1.4. Market size and forecast, by End User
  - 7.2.5.2. Canada
  - 7.2.5.2.1. Key market trends, growth factors and opportunities
  - 7.2.5.2.2. Market size and forecast, by Therapy Type
  - 7.2.5.2.3. Market size and forecast, by Indication
  - 7.2.5.2.4. Market size and forecast, by End User
7.3. Europe
- 7.3.1. Key trends and opportunities
- 7.3.2. Market size and forecast, by Therapy Type
- 7.3.3. Market size and forecast, by Indication
- 7.3.4. Market size and forecast, by End User
- 7.3.5. Market size and forecast, by country
  - 7.3.5.1. Germany
  - 7.3.5.1.1. Key market trends, growth factors and opportunities
  - 7.3.5.1.2. Market size and forecast, by Therapy Type
  - 7.3.5.1.3. Market size and forecast, by Indication
  - 7.3.5.1.4. Market size and forecast, by End User
  - 7.3.5.2. France
  - 7.3.5.2.1. Key market trends, growth factors and opportunities
  - 7.3.5.2.2. Market size and forecast, by Therapy Type
  - 7.3.5.2.3. Market size and forecast, by Indication
  - 7.3.5.2.4. Market size and forecast, by End User
  - 7.3.5.3. UK
  - 7.3.5.3.1. Key market trends, growth factors and opportunities
  - 7.3.5.3.2. Market size and forecast, by Therapy Type
  - 7.3.5.3.3. Market size and forecast, by Indication
  - 7.3.5.3.4. Market size and forecast, by End User
  - 7.3.5.4. Rest of Europe
  - 7.3.5.4.1. Key market trends, growth factors and opportunities
  - 7.3.5.4.2. Market size and forecast, by Therapy Type
  - 7.3.5.4.3. Market size and forecast, by Indication
  - 7.3.5.4.4. Market size and forecast, by End User
7.4. Asia-Pacific
- 7.4.1. Key trends and opportunities
- 7.4.2. Market size and forecast, by Therapy Type
- 7.4.3. Market size and forecast, by Indication
- 7.4.4. Market size and forecast, by End User
- 7.4.5. Market size and forecast, by country
  - 7.4.5.1. Japan
  - 7.4.5.1.1. Key market trends, growth factors and opportunities
  - 7.4.5.1.2. Market size and forecast, by Therapy Type
  - 7.4.5.1.3. Market size and forecast, by Indication
  - 7.4.5.1.4. Market size and forecast, by End User
  - 7.4.5.2. China
  - 7.4.5.2.1. Key market trends, growth factors and opportunities
  - 7.4.5.2.2. Market size and forecast, by Therapy Type
  - 7.4.5.2.3. Market size and forecast, by Indication
  - 7.4.5.2.4. Market size and forecast, by End User
  - 7.4.5.3. Rest of Asia-Pacific
  - 7.4.5.3.1. Key market trends, growth factors and opportunities
  - 7.4.5.3.2. Market size and forecast, by Therapy Type
  - 7.4.5.3.3. Market size and forecast, by Indication
  - 7.4.5.3.4. Market size and forecast, by End User
7.5. LAMEA
- 7.5.1. Key trends and opportunities
- 7.5.2. Market size and forecast, by Therapy Type
- 7.5.3. Market size and forecast, by Indication
- 7.5.4. Market size and forecast, by End User
- 7.5.5. Market size and forecast, by country
  - 7.5.5.1. Latin America
  - 7.5.5.1.1. Key market trends, growth factors and opportunities
  - 7.5.5.1.2. Market size and forecast, by Therapy Type
  - 7.5.5.1.3. Market size and forecast, by Indication
  - 7.5.5.1.4. Market size and forecast, by End User
  - 7.5.5.2. Middle East And Africa
  - 7.5.5.2.1. Key market trends, growth factors and opportunities
  - 7.5.5.2.2. Market size and forecast, by Therapy Type
  - 7.5.5.2.3. Market size and forecast, by Indication
  - 7.5.5.2.4. Market size and forecast, by End User

CHAPTER 8: COMPETITIVE LANDSCAPE

8.1. Introduction
8.2. Top winning strategies
8.3. Product Mapping of Top 10 Player
8.4. Competitive Dashboard
8.5. Competitive Heatmap
8.6. Top player positioning, 2022

CHAPTER 9: COMPANY PROFILES

9.1. Novartis AG
- 9.1.1. Company overview
- 9.1.2. Key Executives
- 9.1.3. Company snapshot
- 9.1.4. Operating business segments
- 9.1.5. Product portfolio
- 9.1.6. Business performance
9.2. Autolus Therapeutics
- 9.2.1. Company overview
- 9.2.2. Key Executives
- 9.2.3. Company snapshot
- 9.2.4. Operating business segments
- 9.2.5. Product portfolio
- 9.2.6. Business performance
- 9.2.7. Key strategic moves and developments
9.3. Caribou Biosciences, Inc
- 9.3.1. Company overview
- 9.3.2. Key Executives
- 9.3.3. Company snapshot
- 9.3.4. Operating business segments
- 9.3.5. Product portfolio
- 9.3.6. Business performance
- 9.3.7. Key strategic moves and developments
9.4. Gilead Sciences, Inc.
- 9.4.1. Company overview
- 9.4.2. Key Executives
- 9.4.3. Company snapshot
- 9.4.4. Operating business segments
- 9.4.5. Product portfolio
- 9.4.6. Business performance
- 9.4.7. Key strategic moves and developments
9.5. Immunocore Ltd.
- 9.5.1. Company overview
- 9.5.2. Key Executives
- 9.5.3. Company snapshot
- 9.5.4. Operating business segments
- 9.5.5. Product portfolio
- 9.5.6. Business performance
- 9.5.7. Key strategic moves and developments
9.6. Celyad Oncology
- 9.6.1. Company overview
- 9.6.2. Key Executives
- 9.6.3. Company snapshot
- 9.6.4. Operating business segments
- 9.6.5. Product portfolio
- 9.6.6. Key strategic moves and developments
9.7. Cartesian Therapeutics, Inc.
- 9.7.1. Company overview
- 9.7.2. Key Executives
- 9.7.3. Company snapshot
- 9.7.4. Operating business segments
- 9.7.5. Product portfolio
9.8. Johnson & Johnson
- 9.8.1. Company overview
- 9.8.2. Key Executives
- 9.8.3. Company snapshot
- 9.8.4. Operating business segments
- 9.8.5. Product portfolio
- 9.8.6. Business performance
- 9.8.7. Key strategic moves and developments
9.9. Bristol-Myers Squibb Company
- 9.9.1. Company overview
- 9.9.2. Key Executives
- 9.9.3. Company snapshot
- 9.9.4. Operating business segments
- 9.9.5. Product portfolio
- 9.9.6. Business performance
9.10. Cellectis, Inc.
- 9.10.1. Company overview
- 9.10.2. Key Executives
- 9.10.3. Company snapshot
- 9.10.4. Operating business segments
- 9.10.5. Product portfolio
- 9.10.6. Business performance