PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1730744
PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1730744
Automated NGS Library Preparation Market size was valued at USD 775 Million in 2024, expanding to a CAGR of 14.1% from 2025 to 2032.
Automated NGS (Next-Generation Sequencing) library preparation refers to the use of robotics or automated systems to perform the steps needed to prepare DNA or RNA samples for sequencing. The "library" is a collection of DNA fragments that have been processed and tagged with adapters so they can be read by an NGS machine.
Automated NGS Library Preparation Market- Market Dynamics
Increasing demand for high-throughput sequencing and advancement in clinical diagnosis & genome research is expected to propel market demand
Next-generation sequencing has become a cornerstone of modern genomics, enabling large-scale genomic, transcriptomic, and epigenomic studies. The need for high-throughput sequencing is growing exponentially due to the increasing volume of genomic data generated across various sectors, including biomedical research, agriculture, and infectious disease surveillance, thereby boosting market growth. Automated NGS library preparation systems help laboratories process hundreds to thousands of samples with minimal manual intervention. This scalability is crucial for population-scale studies, personalized medicine initiatives, and large diagnostic programs like cancer genomics and newborn screening.
One of the most impactful applications of NGS is in clinical diagnostics, particularly in oncology, rare disease diagnosis, and infectious disease testing. As personalized and precision medicine gain traction, the need for fast, reliable, and reproducible sequencing workflows becomes critical. Automation ensures consistency across samples, which is vital for clinical validity and regulatory compliance. Automated systems reduce human error, cross-contamination, and variability, enabling labs to meet the stringent quality standards required in clinical diagnostics. In addition, large-scale initiatives like the 100,000 Genomes Project (UK), All of Us Research Program (USA), and Genome India Project are creating massive demand for scalable, high-throughput sequencing workflows, including automated library preparation. Such initiatives are not only fueling market demand but also encouraging the development of more user-friendly, cost-effective automation solutions
Automated NGS Library Preparation Market- Key Insights
As per the analysis shared by our research analyst, the global market is estimated to grow annually at a CAGR of around 14.1% over the forecast period (2025-2032)
Based on Type segmentation, the targeted genome sequencing segment was predicted to show maximum market share in the year 2024, due to its high accuracy in genomic analysis.
Based on Workflow segmentation, the nucleic acid extraction segment was the leading Workflow segment in 2024, due to the high demand from downstream NGS applications.
Based on Application segmentation, the drug & biomarker discovery segment was the leading material segment in 2024, owing to the high demand for new drug development.
Based on End Use segmentation, the pharma & biotech companies' segment was the leading End Use segment in 2024, mainly due to the increasing need for precision medicine.
Based on the region, North America was the leading revenue generator in 2024, owing to the early adoption of advanced sequencing technologies.
The Global Automated NGS Library Preparation Market is segmented based on Type, Workflow, Application, End Use, and Region.
The market is divided into four categories based on Type: targeted genome sequencing, whole genome sequencing, whole exome sequencing, and others. The targeted genome sequencing segment dominates the market. Targeted genome sequencing is highly preferred due to its high accuracy and precise detection application.
The market is divided into four categories based on Workflow: nucleic acid extraction, fragmentation, adapter ligation, and purification & quantification. The nucleic acid extraction segment is expected to hold the largest share as it offers high-quality genome sequencing.
The market is divided into three categories based on Application: drug & biomarker discovery, disease diagnostics, and others. The drug & biomarker discovery segment is expected to hold the largest share. The disease diagnostics segment is anticipated to grow at the fastest rate due to the high prevalence of cancer and other disorders.
The market is divided into four categories based on End Use: hospitals & clinics, pharma & biotech companies, genomic research institutes, and others. The pharma & biotech companies segment holds the highest share of the End Use segment. Advancements in automation & rapid drug developments are fueling segment demand.
Automated NGS Library Preparation Market- Geographical Insights
Across the globe, the Automated NGS Library Preparation market is widespread in the regions of North America, Latin America, Europe, Asia Pacific, the Middle East and Africa. North America holds the largest share in the global Automated NGS Library Preparation market. Robust investments in genomic research and healthcare infrastructure, and the presence of major market players like Illumina Inc. and Thermo Fisher Scientific Inc., are fueling regional growth. The Asia-Pacific region is expected to witness the highest growth rate, due to the high prevalence of genetic disorders. Emerging markets in Latin America and, Middle East are witnessing the gradual adoption of NGS technologies, driven by collaborations with international research institutions.
The automated NGS library preparation market is moderately fragmented. The market is dominated by several major companies employing strategies such as product innovation, strategic partnerships, and acquisitions to strengthen their positions. Key players are investing in innovative solutions and expanding their global presence to capitalize on the growing demand for NGS technologies. For example, Roche has developed a fully automated, integrated sequencing solution providing end-to-end control for library preparation and target enrichment.
In February 2025, seqWell introduced a MosaiX Library Prep Kit for human population genomic applications such as WGS.
In June 2024, SPT Labtech and Watchmaker Genomics collaborated to develop automated mRNA and DNA sequencing protocols.