PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1782020
PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1782020
Liquid Biopsy Market size was valued at US$ 12,124.24 Million in 2024, expanding at a CAGR of 11.6% from 2025 to 2032.
A liquid biopsy is a non-invasive diagnostic procedure that evaluates bodily fluids, mainly blood, to identify cancer or other illnesses. It analyzes biomarkers such as circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) to detect genetic or molecular alterations linked to a tumor. Liquid biopsies can facilitate early cancer detection, monitor the effectiveness of treatments, and evaluate tumor progression. Much of the initial research on liquid biopsies has focused on lung, breast, and prostate cancers; however, this technology is anticipated to influence all cancer types. Liquid biopsy represents a relatively recent testing method with numerous potential revolutionary applications in cancer therapy, including several uses that have received approval from the U.S. Food and Drug Administration (FDA). Ongoing research continues to explore its advantages.
Liquid Biopsy Market- Market Dynamics
The increasing prevalence of cancer is anticipated to boost the demand for early screening and therapeutics, thereby driving market growth.
As cancer emerges as a primary contributor to morbidity and mortality globally, healthcare systems are increasingly prioritizing early-stage diagnostics to detect malignancies before their advancement. This shift is propelling the utilization of sophisticated screening technologies, including liquid biopsies, imaging techniques, and molecular diagnostic assessments. The National Cancer Institute projects that by 2025, approximately 2,041,910 new cancer cases will be identified in the United States, with 618,120 fatalities attributed to the disease. Consequently, the cancer care continuum, encompassing early diagnosis through to treatment, is rapidly evolving to address the escalating healthcare demands, thereby further stimulating the market for both early screening instruments and groundbreaking therapeutics. Additionally, advancements in genomic and molecular technologies may present growth opportunities for the market. Nevertheless, the lack of standardization and regulatory hurdles could impede market expansion.
Liquid Biopsy Market- Key Insights
As per the analysis shared by our research analyst, the global market is estimated to grow annually at a CAGR of around 11.6% over the forecast period (2025-2032)
Based on the Sample Type segmentation, the Blood Sample was predicted to show maximum market share in the year 2024
Based on Biomarker segmentation, Circulating Tumor Cells (CTCs) were the leading application in 2024
Based on Technology segmentation, Multi-gene-parallel Analysis (NGS) was the leading Technology in 2024
Based on Product segmentation, Instruments were the leading Product in 2024
Based on Clinical application segmentation, Therapy Selection was the leading End-User in 2024
Based on Application segmentation, Cancer was the leading End-User in 2024
Based on End-User segmentation, Hospitals and Laboratories were the leading End-User in 2024
Based on region, North America was the leading revenue generator in 2024
The Global Liquid Biopsy Market is segmented based on Sample Type, Application, Technology, Product, Clinical Application, Application, End-User, and Region.
The market is categorized into three segments according to Sample Type: Blood Sample and Others. Blood Sample is the primary driver of market growth. Blood samples dominate the Liquid Biopsy sector, mainly due to their ease of collection, low invasiveness, and high levels of patient compliance. Blood-based liquid biopsies facilitate the detection and analysis of circulating tumor DNA (ctDNA), circulating tumor cells (CTCs), and various other biomarkers, providing a thorough overview of the tumor's genetic profile in real-time. In comparison to tissue biopsies, blood samples offer a quicker, safer, and more economical option for cancer diagnosis, prognosis, treatment monitoring, and early detection. The extensive adoption of blood-based tests by hospitals, diagnostic centers, and research institutions further reinforces their leading position in the market.
The market is categorized into three segments based on biomarkers: Circulating Tumor Cells (CTCs), Circulating Tumor DNA (ctDNA), and Extracellular Vehicles (EVs), among others. Circulating Tumor Cells (CTCs) lead the growth of the market. CTCs are the primary drivers of growth in the Liquid Biopsy market, due to their significant role in cancer diagnosis, prognosis, and treatment monitoring. CTCs are cancer cells that separate from primary or metastatic tumors and travel through the bloodstream, providing essential insights into tumor heterogeneity and metastatic potential. Their capacity to deliver real-time data on disease progression and treatment response without requiring invasive procedures renders them a preferred biomarker in oncology.
The market is categorized into two segments based on technology: Multi-gene-parallel Analysis (NGS) and Single Gene Analysis (PCR Microarrays). Multi-gene-parallel Analysis (NGS) is the primary driver of market growth. The multi-gene parallel analysis utilising Next-Generation Sequencing (NGS) leads to the growth of the Liquid Biopsy market, owing to its capability to concurrently assess multiple genetic alterations with exceptional sensitivity and specificity. NGS facilitates extensive genomic profiling from small sample volumes, equipping clinicians with in-depth insights into tumor biology, mutation load, and possible therapeutic targets. This methodology is particularly beneficial for personalized medicine, as it enables the identification of rare mutations and resistance mechanisms in real time. The rising implementation of NGS-based liquid biopsy panels in oncology for early cancer detection, treatment selection, and monitoring of minimal residual disease is greatly enhancing the market's growth.
The market is segmented into three categories based on Product: Instruments, Consumables Kits and Reagents, and Software and Services. Instruments lead the growth of the market. Instruments are at the forefront of the Liquid Biopsy market expansion, propelled by the rising demand for sophisticated technologies that can accurately identify and analyze circulating biomarkers such as circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), and exosomes. These instruments, which include NGS platforms, PCR systems, microfluidic devices, and automated liquid handling systems, are crucial for achieving high throughput, sensitivity, and precision in diagnostic processes. The ongoing advancement of innovative, user-friendly, and integrated systems designed for oncology applications has accelerated their adoption in hospitals, diagnostic laboratories, and research institutions.
The market is categorized into four segments based on Clinical Application: Therapy Selection, Treatment Monitoring, Early Cancer Screening, Recurrence Monitoring, and Others. Therapy Selection is the primary driver of market growth. By examining circulating tumor DNA (ctDNA) or other biomarkers, liquid biopsy facilitates the detection of specific mutations, gene fusions, and resistance mechanisms without requiring invasive tissue sampling. This method enables oncologists to customize therapies such as targeted treatments or immunotherapies according to a patient's distinct molecular profile, thereby enhancing clinical outcomes and reducing unnecessary toxicity. The increasing focus on precision medicine, coupled with the capability of liquid biopsy to track dynamic tumor alterations during treatment, further reinforces its essential role in therapy selection across different cancer types.
The market is categorized into eight segments based on application: Cancer, Reproductive Health, Lung Cancer, Prostate Cancer, Breast Cancer, Colorectal Cancer, Leukemia, Gastrointestinal Cancer, and Others. The cancer segment is at the forefront of market growth. In the Liquid Biopsy sector, the cancer segment is driving market expansion, propelled by the increasing global prevalence of various cancers and the rising demand for non-invasive diagnostic methods. Liquid biopsy provides a revolutionary method for the early detection of cancer, tumor profiling, treatment monitoring, and predicting relapses by examining biomarkers such as ctDNA, CTCs, and exosomes derived from body fluids-mainly blood. Its benefits over conventional tissue biopsies, which include reduced risk, faster turnaround times, and the capacity to capture tumor heterogeneity, have established it as an essential instrument in oncology. As precision medicine becomes more integral to cancer treatment, the application of liquid biopsy in the management of solid tumors like lung, breast, colorectal, and prostate cancer is continually growing, further propelling the advancement of this segment.
The market is categorized into four segments based on End-User: Hospitals and Laboratories, Specialty Clinics, Academic and Research Centers, and Others. The Hospitals and Laboratories segment is at the forefront of market growth. This segment is driving the expansion of the Liquid Biopsy industry due to the increasing adoption of advanced diagnostic technologies and the growing number of cancer screening and monitoring procedures conducted in these environments. Hospitals and clinical laboratories frequently serve as the initial point of contact for patients undergoing diagnostic assessments, rendering them essential centers for the deployment of liquid biopsy tests. These institutions gain advantages from the presence of skilled professionals, established infrastructure, and access to high-throughput instruments such as NGS and PCR platforms.
Liquid Biopsy Market- Geographical Insights
North America leads in market growth, attributed to robust research and development as well as a solid reimbursement framework. The region's sophisticated healthcare system heightened awareness regarding early cancer screening, and strong partnerships between academic institutions and industry stakeholders further solidify North America's prominent role in the global liquid biopsy market. As reported by the American Medical Association, the United States allocated USD 4,866.5 billion for healthcare in 2023. Europe also orders a substantial portion of the market, bolstered by increasing cancer awareness, enhanced access to healthcare, and government funding for early detection initiatives.
The liquid biopsy market is characterized by intense competition and constant evolution, with numerous established and new entrants seeking to secure a competitive advantage through innovation, collaborations, and growth strategies. Firms are competing based on cutting-edge technologies such as next-generation sequencing (NGS), droplet digital PCR, and multi-gene panel testing to enhance the sensitivity, specificity, and speed of liquid biopsy assays. Leading companies are placing greater emphasis on emerging markets in the Asia Pacific and Latin America by setting up regional subsidiaries and distribution networks to seize untapped opportunities.
On November 1, 2023, Illumina Inc., a worldwide frontrunner in DNA sequencing and array-based technologies, announced the launch of a new generation of its distributed liquid biopsy assay designed for genomic profiling. The latest TruSight Oncology 500 ctDNA v2 (TSO 500 ctDNA v2) is a research assay that facilitates noninvasive comprehensive genomic profiling (CGP) of circulating tumor DNA (ctDNA) extracted from blood samples when tissue testing is not feasible, or enhances tissue-based testing.