PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1877443
PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1877443
The Placental Stem Cell Therapy Market size was valued at US$ 455 Million in 2024, expanding at a CAGR of 18.5% from 2025 to 2032.
Placental Stem Cell Therapy leverages placental-derived stem cells to treat neurological and other disorders. A key market trend is the growing emphasis on regenerative medicine, highlighting the ability of stem cells to repair or replace damaged neurons and address unmet medical needs in neurological conditions. Advances in biotechnology and stem cell research are accelerating market growth. However, regulatory challenges remain a significant barrier, as stringent approval processes can delay market entry and increase development costs. Additionally, the high cost of therapies limits accessibility, constraining patient reach and overall market expansion.
Placental Stem Cell Therapy Market- Market Dynamics
Technological Advances and Innovative Research Drive Market Growth
Technological advancements and innovative research are critical drivers of growth in the placental stem cell therapy market. Cutting-edge technologies improve the isolation, processing, and application of stem cells, thereby increasing treatment efficiency and safety. For instance, in November 2023, researchers from the Critical Analytics for Manufacturing Personalized Medicine (CAMP) Interdisciplinary Research Group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), in collaboration with ASTAR's Bioprocessing Technology Institute (BTI) and the National University Health System (NUHS), developed a technology to extract mesenchymal stem cells (MSCs) directly from pure bone marrow aspirate, streamlining. This demonstrates how research breakthroughs drive market growth.
The worldwide market is segmented on the basis of Therapy Type, Cell Type, End-user, Application, and Region.
The therapy type segment is primarily divided into two groups Allogeneic Therapy and Autologous Therapy. Allogeneic therapies are an important segment due to their "off-the-shelf" availability. These donor-derived cell products can be cryopreserved and used right away, making them ideal for emergency neurological care where prompt intervention is required. This operational advantage eliminates the time and expense associated with patient-specific (autologous) cell harvesting. This shift is also being supported by global regulatory focuses; in 2023, the World Health Organization endorsed updated global principles for human cell and tissue therapies, strengthening quality, traceability, and safety standards across member states and allowing for broader deployment of allogeneic cell products in clinical settings. Furthermore, national regenerative-medicine policies are accelerating scale-up; for example, Japan's PMDA approved over 20 new cell- and tissue-based therapy trials between 2022 and 2024, many of which used allogeneic cell banking systems to reduce manufacturing time. These clinical and regulatory factors place allogeneic placental stem cell therapies in a strategic position to contribute to market growth.
Based on End user segment, Academic and research institutions play critical roles in the development of placental stem cell therapies. Their work frequently focuses on understanding the biology, safety, and therapeutic potential of placental-derived mesenchymal stromal cells (MSCs), as well as developing good manufacturing practices (GMP) protocols and preclinical efficacy in neurological models. A 2024 study published in Frontiers in Bioscience by a university-affiliated research center found that human placenta-derived MSCs significantly improved neurological outcomes in a rat model of hypoxic-ischemic encephalopathy by reducing inflammation and neuronal apoptosis.
Placental Stem Cell Therapy Market- Geographical Insights
North America has a significant market share for placental stem cell therapy. Adoption in the region is being driven by a growing awareness of placental stem cells' therapeutic potential for neurological conditions. Increased patient interest in alternative treatments for neurological disorders, combined with advances in therapy development, is driving market growth. Collaborations among academic institutions, healthcare providers, and biotechnology companies have facilitated the establishment of specialized facilities, increased accessibility and allowing clinical applications of placental stem cell therapies for neurological conditions.
United States Placental Stem Cell Therapy Market- Country Insights
The United States plays a pivotal role in generating revenue within the placental stem cell therapy market for neurological disorders, driven by the increasing prevalence of age-associated conditions such as Alzheimer's and Parkinson's disease. By 2050, it is projected that 13 million Americans aged 65 and older will be living with Alzheimer's, up from approximately 7.2 million in 2025. In 2024, nearly 12 million Americans provided unpaid care for individuals suffering from dementia, highlighting the urgent need for effective therapies. Additionally, nearly one million Americans are affected by Parkinson's disease, with risk increasing sharply with age. These statistics underscore the rising demand for innovative treatment options, positioning placental stem cell therapies as a significant therapeutic approach for managing neurological disorders in the U.S.
The placental stem cell therapy market is moderately concentrated, with a few key players driving innovation and expanding their global presence. Thermo Fisher Scientific, Inc., Cell Applications, Inc., Bio-Techne, and Cellular Engineering Technologies are among the leading companies that specialize in developing advanced stem cell therapies for neurological and other degenerative disorders. These companies compete by developing new cell isolation, storage, and delivery technologies that improve safety, efficacy, and patient outcomes. For example, Pluristem Therapeutics announced a strategic partnership with a biopharmaceutical company in the United States in February 2024 to advance clinical trials of placental-derived mesenchymal stem cells for ischemic stroke treatment, and to enter the market quickly. Continuous R&D investments, collaborations with academic institutions, and regulatory approvals that facilitate product commercialization all help to shape market competition. To meet the increasing global demand for regenerative therapies, expansion strategies include strengthening manufacturing capabilities and entering emerging markets.
In December 2024, Mesoblast Limited has announced that Ryoncil (remestemcel-L) has received FDA approval as the first mesenchymal stromal cell (MSC) therapy in the United States. Ryoncil is now the only MSC therapy approved in the United States, as well as the first treatment for steroid-resistant acute graft-versus-host disease (SR-aGvHD) in children as young as two months old, including adolescents and teenagers. Dr. Joanne Kurtzberg, a leading transplant physician at Duke University Medical Center, emphasized the importance of this approval, stating that Ryoncil provides a life-saving option for children with this severe condition, giving hope to both patients and their families.
In October, 2024, Aspen Neuroscience, Inc. has announced the expansion of its San Diego operations with a new 22,000 square foot facility dedicated to the GMP manufacturing of induced pluripotent stem cell (iPSC)-based therapies. This facility, located near the company's headquarters, will manufacture ANPD001, an iPSC-derived cell therapy for Parkinson's disease, as part of the ASPIRO trial. The expansion includes ISO-certified manufacturing suites, quality control labs, and more room for future growth and automation. Aspen is also working to industrialize autologous cell therapy manufacturing to improve throughput and streamline production processes.