The Worldwide Orthopedic & Spine Contract Manufacturing Market Report 2024-2030 and Top 100 Supplier Profiles, 14th Edition

Description

Overview:

This report contains 400+ pages and 1200+ exhibits and 100+ company profiles. It detailed the worldwide orthopedic Contract Manufacturing market and analysis for the following segments:

Forging: Hip stem, hip cup, femoral knee, tibial knee, shoulder stem, shoulder glenoid, LF plates, LC plates
Casting: Femoral knee, tibial knee, hip cup, hip stem
Hip machining and finishing: Stem, cup, head, liner
Knee machining and finishing: Insert, tibial, femoral components
Shoulder machining and finishing: Stem, glenoid, other parts
Spine machining and finishing: Lumbar Universal Systems, spine plates, spine screws and cages
Trauma machining and finishing: Plates, screws, nails, intramedullary hip screws, compression hip screws...
Extremities machining and finishing: Foot plates, foot screws, hand, wrist & elbow plates, hand, wrist & elbow screws...
Instrument machining and finishing: Hip, knee, spine, trauma, shoulder, extremities
Cases and trays: Hip, knee, spine, trauma
Coating: Stem, cup, femoral, tibial components
Ceramics: Femoral heads, cup liners
Marking, packaging and sterilization: Hip, knee, spine, trauma.

This report provides also details and analysis for the following segments:

By OEM orders
By services & products offered for all segments & sub-segments (volume, value)
By Contract Manufacturing market share & player details:
- Implants: Tecomet, Orchid, Viant, Lisi, Avalign, Marle, Norman Noble, PCC, Paragon, Mediliant Group, etc. (70+ companies mentioned)
- Instruments: Tecomet, Viant, Intech, Avalign, Autocam Medical, Norwood, Orchid, Lisi, Tegra, etc. (45+)
- Cases & trays: Tecomet, Paragon, Viant, Avalign, Medin, Intech, RMS, Inomed, etc. (20+)
- Coating: Orchid, Lincotek, Viant, DOT, APS Materials, Terolab, Medical, Medicoat, etc.
- Ceramics: Ceramtec, Coorstek, Kyocera, Metoxit, etc.
- 3D Printing: Stryker, Zimmer Biomet, Lima, Adler, Lincotek, Cretex, Avalign as well as Arcam, EOS, Concept Laser, SLM, 3D Systems, Renishaw, etc.
- Packaging : Amcor, Oliver, Millstone, Nelipack, etc.
- Sterilization: Steris, Sterigenics, Ionisos, etc.
- Orthobiologics: Heraeus, RTI surgical, Biocomposites, Tecres, Bonesupport, Teknimed Subiton, etc.
- Raw materials, Peek, Polyethylene UHMW: Invibio, Solvay, Evonik, PPD Meditech, etc.
Top 100 players with market share in each segment
Orthopedics Additive Manufacturing market analysis: users, suppliers, products focused on & forecasts

Main report focus area:

Products: hip, knee, spine, trauma, extremities and shoulder
Services: forging, casting, machining, coating, packaging, sterilization, ceramics, cases & trays & 3D printing.

New updates:

Complete overview of the orthopedic end-user market: markets, prices, players, strategic trends & moves
Destocking by orthopedic companies and impact on CMOs
Spine, Trauma, extremities and shoulder contract manufacturing, detailed and separate analyses
Inflation: Impact on the contract manufacturing business and the orthopedic end-user market
3D printing for orthopedics: Contract manufacturing & in-house market sizes and forecasts by 2030
MDR: Decreased competitiveness of the European orthopedic industry, scenarios of short and long terms impact on the players
Robotics for orthopedics: Penetration of robotics for players like Stryker, Zimmer-Biomet, Depuy-Synthes, Think Surgical, etc.
Chrome Cobalt: What are the alternatives and when will they be available?
A plethora of strategic information on the Top 100 contract manufacturers, with 150 profiles - included those of acquired companies

Product Code: CM 14-2025

Purpose of the Survey and Methodology Synopsis & Executive summary

Segmentation
Worldwide Orthopedic market in 2024: by product & by player
Worldwide Orthopedic market in 2024: Majors Vs challengers
Worldwide Orthopedic market in 2024: life cycle of orthopedic products and forecasts for 2030
Orthopedic Contract Manufacturing value chain
Contract Manufacturing market & trends: Forging
Contract Manufacturing market & trends: Casting
Contract Manufacturing market & trends: Instrument machining
Contract Manufacturing market & trends: Instruments is a highly fragmented market
Contract Manufacturing market & trends: Coating
Contract Manufacturing market & trends: Cases & trays
Contract Manufacturing market & trends: Ranking of top players
Orthopedic Contract Manufacturing market & trends: Top20, Top 21-100 and top 101 -1 000 distribution of revenues
Orthopedic Contract Manufacturing market & trends: consolidation by acquisition- Forecasts by service for 2030
The Orthopedics Contract Manufacturing market is growing faster than In-house manufacturing
Orthopedic Contract Manufacturing market & trends: Additive Manufacturing for hip, knee, knee, shoulder& trauma
Orthopedic Contract Manufacturing market & trends: Additive Manufacturing for spine & Additive Manufacturing machines in 2024 and usage forecasts for 2030

1. Orthopedic environment

Contract Manufacturing market value chain
Orthopedics Macro environment: Political, Economical, social/culture, technological, environment, legal & regulatory
Market Drivers
Global population growth 1950-2050 and people over 65
The market drivers
- Demographic & Economic
- Orthopedics is generally risk-averse with few disruptive innovations, many small incremental innovations
- Innovation and new products pull the market
- Innovative surgeons are looking for new products, % of the surgeons by category in each type of country
The market limiters
- Regulatory & Certification
- Reimbursement and pricing regulation
- MDR (Medical Device Regulation): Impact in Europe
- A product's CE marked under MDD will remain valid for about 5 years, which will necessitate a mandatory request for validation under MDR, backed up by clinical studies, before the MDD expiry date: details
- Hip Price trends in Europe show regular decrease
- Reimbursement price decreases are not frequent, hence they have been manageable over the long term
- Hip ASP erosion in developed countries
- Hip average price trend in Europe 2003-2024: France, Germany, UK, Italy, Average Europe
- Reimbursement HIP average price trend in Europe (Euro), including country disparities
- Group purchasing in Germany, France and Italy
- The orthopedic sales channels

2. Worldwide orthopedic & spine market; players, drivers & limiters and forecasts 2024 - 2030

Orthopedics Ecosystem
Worldwide orthopedic markets in 2024 by product
Worldwide implants market in 2024 by value (B$): Knee, hip, spine and by area, USA, Europe, Row
Worldwide implants market knee, hip & spine in 2024 by value (BUS$)
Worldwide implants market Trauma, shoulder & Extremities in 2024 by value (BUS$)
Hip & Knee sales per area: USA, Europe, Japan, Australia, Korea & Row
Ratio for 10,000 inhabitants & growth by area (2024)
Worldwide orthopedic market in 2024: competition
Worldwide competition by product in 2024: Market share
Three types of Challengers competing with the Majors
Top 4 vs. Challengers for hip & knee worldwide markets: Majors have no growth while challengers are growing fast
Note: If we exclude Stryker, the results are much more revealing: The 3 majors have been flat over 10 years, while the challengers have grown by 5.5% per year
Hip, knee & shoulder challengers are growing faster than the market average
Spine challengers are grabbing market share from the Majors and emerging as top players with revenues ranging from US$0.5B - US$1B
Spine: Worldwide market shares 2012-2024: Majors limit market share losses by buying rivals
Trauma: Worldwide player market shares, 2016-2024
Hip Europe market share 2012-2024: Depuy Synthes, Zimmer Biomet, Stryker, Smith & Nephew & other
Knee Europe market share 2012-2024: Depuy Synthes, Zimmer Biomet, Stryker, Smith & Nephew & other
Challengers have continuously gained market share 2018-2024 - Except in 2020 due to Covid impact
Majors Vs Challengers : Revenues CAGR, market shares
Majors Vs Challengers: 2024 picture
Challengers growing Vs majors
Smith & Nephew and ATEC comparison: average new products launched per year
Reasons why Challengers are growing faster than Majors (except during Covid crisis)
Hip ASP erosion in developed countries 2012-2024
Knee ASP erosion in developed countries 2012-2024
Forecast Price erosion 2024 -2030: USA, Australia, Japan, Europe
The life cycle of orthopedic products: Growth forecasts by 2030 for hip, knee, spine, extremities
Worldwide orthopedic market forecasts 2000-2030 for hip, knee, extremities, shoulder, trauma, spine, orthobiologics & Others
Summary: Orthopedic market

3. Worldwide orthopedic & spine Contract Manufacturing market, OEM strategies, Contract Manufacturers position, market share and forecasts to 2030

Zimmer Biomet: main facilities details
OEM contract manufacturing strategy: Zimmer Biomet
OEM contract manufacturing strategy: Stryker
OEM contract manufacturing strategy: Depuy Synthes
OEM contract manufacturing strategy: Smith & Nephew
OEM contract manufacturing needs: Medtronic
OEM contract manufacturing needs: Globus-Nuvasive
OEM contract manufacturing needs: Challengers
Contract Manufacturing process segmentation & raw materials: 14 segments & 70 sub-segments
Forging Contract Manufacturing market 2024
Forging Contract Manufacturing market 2012-2030 by product
Forging Contract Manufacturing market share in 2024: Tecomet, Marle, Orchid, Lisi, PMP, etc
Forging Contract Manufacturing market: OEMs relationships with their suppliers
Casting Contract Manufacturing market 2024
Casting Contract Manufacturing market 2012-2030 by product
Casting Contract Manufacturing market share in 2024: Orchid, PCC, Marle, Lincotek, Tecomet, etc
Casting Contract Manufacturing market: OEMs relationships with their suppliers
Hip machining & finishing Contract Manufacturing market 2024
Hip machining & finishing Contract Manufacturing market 2012-2030 by product
Knee machining & finishing Contract Manufacturing market 2024
Knee machining & finishing Contract Manufacturing market 2012-2030 by product
Shoulder machining & finishing Contract Manufacturing market 2024
Shoulder machining & finishing Contract Manufacturing market 2012-2030 by product
Spine implants machining & finishing Contract Manufacturing market 2024
Spine implants machining & finishing Contract Manufacturing market 2012-2030
Trauma implants machining & finishing Contract Manufacturing market 2024
Trauma implants machining & finishing Contract Manufacturing market 2012-2030
Extremities implants machining & finishing Contract Manufacturing market 2024
Extremities implants machining & finishing Contract Manufacturing market 2012-2030
Spine, Trauma, Extremities & Shoulder Contract Manufacturing market 2024-2030
Player market shares: Spine, Trauma, Extremities & Shoulder contract manufacturing in 2024
What are orthopedic instruments for knee, hip, spine, trauma, shoulder & extremities?
Knee orthopedic instruments: functional segmentation
Knee orthopedic instrument segmentation: 150 to 200 pieces
Hip orthopedic instrument segmentation: 80 to 150 pieces
Spine instruments: 30 to 50 pieces
Spine orthopedic instruments - product segmentation
Trauma instruments segmentation: 10 to 20 pieces
The Major OEMs have a different outsourcing strategy Vs the challengers. The challengers outsource almost all their instruments
Instruments life cycle: New OEM projects lead to instruments set manufacturing. When an OEM postpones the launch of its new projects (for example during the 2008 & 2011 crisis & during Covid 19), it also drastically reduces its instruments manufacturing
Cutting tools: Single-use trend: Single-use is a pressing demand from surgeons
Cutting tools: Single-use trend: Single-use is growing rapidly in the US and Europe
Instruments Contract Manufacturing market 2024
Instruments Contract Manufacturing market 2012-2030 by product
Instruments Contract Manufacturing market share in 2024: Tecomet, Intech, Jabil, Paragon, etc
Orthopedic robotic market in 2024: MAKO from Stryker, ROSA from Zimmer Biomet, Corin, TANVI, Navio of Smith, Mazor from Medtronic and Velys from Depuy Synthes
Navigation Vs robotic assisted surgery
Mako's acquisition by Stryker boosted the orthopedic robotic market and have a huge impact on instruments market
Orthopedic robotics surgeries: Stryker open the mass market, Smith & Nephew, Zimmer Biomet, Depuy and many others have followed
New generations of Mako for shoulder and spine surgery planned for the coming years - Roadmap 2013-2024
Zimmer Biomet with Rosa roadmap 2013-2024
Smith & Nephew with Navio & Cori roadmap 2015-2024
Depuy Synthes with Velys roadmap 2018-2024
Robotic orthopedic system benchmark in details: CT scan based or not, technical support
Mako, Rosa, Velys and Cori benchmark Operating cost / Acquisition cost
Robotic assisted surgeries: USA is by far the leading country for Robotics usage. 2014-2024 procedures by robotic systems
Product benchmarking: Mako is the robot with the most extensive clinical track record, but the acquisition cost is high
US knee robotic-assisted surgeries 2020-2030 in units: the USA is by far the leading country for robotics usage. Knee surgery is the first target
Australia was always a pioneer in the use of innovations in orthopedics especially for knee robotic-assisted surgeries. Germany and Japan and France situations
Robotic-assisted surgeries outside the US: Between 2024 and 2030, the number of robotic knee operations outside the USA
What are orthopedic cases & trays?
Cases & trays Contract Manufacturing market 2024
Cases & trays Contract Manufacturing market 2012-2030 by product
Cases & trays Contract Manufacturing top 15 market share in 2024: Tecomet, VIANT, Paragon, Avalign, etc
Ceramics Contract Manufacturing market 2024
Ceramics Contract Manufacturing market 2012-2030 by product
Ceramics Contract Manufacturing market share in 2024: Ceramtec, Kyocera, etc
Coating Contract Manufacturing
Coating Contract Manufacturing market 2024
Coating Contract Manufacturing market 2012-2030 by product
Coating Contract Manufacturing market share in 2024: Orchid, Lincotek, DOT, Viant, APS Materials, etc
MPS Contract Manufacturing market 2024
Marking Packaging & Sterilization -MPS- Contract Manufacturing market 2012-2030 by product
Contract Manufacturing market value chain
Contract Manufacturers worldwide orthopedics revenues in 2024 (in MUS$)
CMO top players: 2017-2024 main M&A activity
Tecomet revenues by area and by customers 2019-2024
Orchid revenues by area and by customers 2019-2024
Viant revenues by area and by customers 2019-2024
Avalign revenues by area and by customers 2019-2024
CMOs leader: presence in different services: forging, casting, machining, coating, instruments, cases & trays, and packaging
CMOs leader: Tecomet, Orchid and Viant - Strengths & Weaknesses
Contract Manufacturing competitor ranking & dispersion
Billing for Orthopedic instruments by geographical area and by players: Jabil, Intech, Tecomet, Arch, paragon, Avalign, Norwood, Autocam, Viant
Orthopedic Contract Manufacturing concentration by acquisition
Contract Manufacturing industry needs more concentration
More outsourcing is a heavy trend for all the orthopedic companies: Outsourcing rate
Continuous trend: OEM facility disinvestments occur when there are opportunities to sell to a large and reliable player, who can guarantee supply security
Depuy Synthes - Jabil: strategic deal to disinvest 14 facilities: initial road map
JABIL Healthcare profile
OEM facility disinvestments: huge impact of Depuy Synthes - Jabil deal for 2019-2020
More outsourcing is a heavy trend for all the orthopedic companies
The risk of moving to LLC by 2030
Contract Manufacturing price range dashboard in 2024
Orthopedics Contract Manufacturing market is growing faster than In-house manufacturing
Contract Manufacturing market is growing at a higher rate than the orthopedic market
Contract Manufacturing market historical revenues & forecasts (MUS$): 2012-2030

4. 3D Printing in Orthopedics

3D Printing & Trabecular in Orthopedics
3D Printing history in Orthopedics
Story of Zimmer and Trabecular Tantalum
Zimmer, Trabecular Metal related implants
3D Printing Manufacturing: Technologies and major competitors, EOS, SLM Solutions, Concept Laser (GE), Arcam (GE), Others
Arcam EBM installed base for orthopedic industry: Lima
Beijing AK MEDICAL EBM Installed base
Illustrative build-up speed and resolution of selected Metal 3D Printing systems: EBM Vs Selective Laser Melting
Smith & Nephew usage of 3D Printing for customized cutting blocks
Stryker's History of 3D Printing: STRYKER, to build a 3D printing manufacturing facility for more than $400 million
Stryker's current products made by 3D printing: Knee, cages, other
Depuy Spine usage of 3D Printing for prototyping of complex surgical tools
Depuy Synthes has acquired 3D Printing technology from Tissue Regeneration Systems Inc
XILLOC invested usage for Cranio-Maxillofacial applications
Equipment suppliers for Orthopedics, Installed base per customer and per supplier: EOS, ARCAM (GE), CONCEPT LASER (GE), SLM Solutions, 3D Systems, Trumpf and their customers
Dozens of companies mentioned with the number of 3D printing machines and type of machines
Addressable market should increase with lower 3D Printing cost: cost and complexity curve linked with addressable market
Additive Manufacturing is attractive for reconstructive implants
Number of implants produced using 3D Printing: Zimmer Biomet, Lima, Exactech, Adler Ortho
FDA clearance for medical devices using 3D Printing in USA
3D Printing has reached the mass market for a few key products
3D Printing today has a slight impact on the forging, casting & machining of implants. Our research shows that Stryker and challengers are most advanced in the use of 3D printing, particularly for hip cups, tibial knee plates and spinal cages
3D printing cages are gaining in market share over Peek and Titanium cages
3D Printing in 2024
3D Printing impact on forging, casting & machining of implants
Cages Raw Materials in the five main European countries: Peek, Titanium Vs 3D Printing
Is 3D Printing the right option for the implant Contract Manufacturing business? Analysis for implants, standard cages, special cages and customized implants: players, products, benefits, drivers and limiters
Is Additive Manufacturing the right option for the instruments Contract Manufacturing business? Analysis of customized cutting guides and instruments
Analysis of one of the most advanced Contract Manufacturers in 3D Printing: Lincotek
Lincotek 3D Printing activity details
Most large contract manufacturers are investing in 3D printing; Orchid, Lincotek, Marle, Paragon, Norman Noble and many others: detail of strategy of each
The most manufactured orthopedic products by 3D Printing: cups, tibial knee, cages, shoulder glenoid,
Standard manufacturing process Vs 3D Printing process: cost comparison in US$
Trend of the installed bases of the main machine suppliers: the number of 3D Printing machines used in orthopedics has grown by 25% per year since 2015: EOS, ARCAM, Concept Laser, 3D Systems, SLM, Renishaw, etc
3D Printing In-house & Contract Manufacturing market: by products (hip cup, knee tibial, shoulder glenoid, spine cage, other) : 2015-2030
In-house and contract manufacturing market by customer: Depuy Synthes, Stryker, Smith & Nephew, Zimmer Biomet, Medtronic, other companies

5. Orthobiologics / Cobalt Chrome / Contract & Design Manufacturing Organization / ASC

Use of antibiotics for orthopedic cements: Need for cements with new antibiotics
Synthetic or natural bone substitutes, allografts, must satisfy many needs: injectable substitutes or more abundant allografts
Top bone grafts on the market: injectables and antibiotics are the main drivers
Cobalt Chrome is today used in many orthopedic products: femoral part of the knee, the cup in dual mobility and some hip heads, etc
Anti-allergic solutions against nickel, cobalt, etc. have been developed for several decades for a patient population considered to represent less than 10% of orthopedic operations
Contract & Design Manufacturing Organization Companies like Tyber and Resolve specialize in the design and development of implants and instruments for orthopedic companies
With the merger of Resolve and Tyber Medical with Intech the new group will dominate the CDMO market - with projected revenues of over US$300M in 2025
TOP 20 CDMO companies: Most of these companies are based in the US
Ambulatory Surgery Center - ASC forecast in the USA

6. Impact of Inflation

Contribution to year-on year CPI (Consumer Price Index) inflation in the G7 countries July 2022
Contribution to year-on year CPI (Consumer Price Index) inflation in the G7 countries September 2022
Contribution to year-on year CPI (Consumer Price Index) inflation in the G7 countries October 2023
Impact of inflation on the end-user market and on contract manufacturing (1/2)
Impact of inflation on the end-user market and on contract manufacturing (2/2)
FX rate variation from January 2018 to September 2024: The Euro has devalued by almost 20% Vs the US Dollar!
Impact of exchange rate fluctuations on the major orthopedic companies: the Majors are impacted in terms of their revenues in Europe! Production will tend to relocate within Europe or to ROW
Impact of exchange rate fluctuations on orthopedic contract manufacturers: Majors contract manufacturers are negatively impacted on their share of sales in Europe
Worldwide orthopedic market 2000-2024
The Orthopedics Contract Manufacturing market is growing faster than In-house manufacturing 2000-2030
Opportunities and risks for orthopedic end-user market
Opportunities and risks for orthopedic contract manufacturing