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PUBLISHER: BCC Research | PRODUCT CODE: 1880569

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PUBLISHER: BCC Research | PRODUCT CODE: 1880569

Protein Expression: Global Markets

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The global market for protein expression is estimated to grow from $4.7 billion in 2025 to reach $7.9 billion by 2030, at a compound annual growth rate (CAGR) of 10.9% from 2025 through 2030.

The North American market for protein expression is estimated to grow from $1.9 billion in 2025 to reach $3.1 billion by 2030, at a CAGR of 10.6% from 2025 through 2030.

The Asia-Pacific market for protein expression is estimated to grow from $951.8 million in 2025 to reach $1.7 billion by 2030, at a CAGR of 12.3% from 2025 through 2030.

Report Scope

The report provides an overview of the global protein expression market and analyzes key market trends. Global revenue ($ million) for the base year 2024 and estimated data for the forecast period, 2025 through 2030, are also included. The market is segmented into expression system, product types, application, end user and regions. The regions covered in this study are North America, Europe, Asia-Pacific (APAC) and the Rest of the World (RoW), with a focus on major countries in these regions.

The report examines trends and challenges that affect the market and vendor landscape; analyzes environmental, social and corporate governance (ESG) developments; and discusses emerging technologies related to the market.

The report concludes with an analysis of the competitive landscape, providing rankings and market shares of key companies in the global protein expression market. A dedicated section of company profiles provides an overview, key financials, product portfolios and recent developments of leading companies, including a patent analysis.

Report Includes

  • 52 data tables and 65 additional tables
  • An overview of the global market for protein expression
  • In-depth analysis of global market trends, featuring historical revenue data for 2022-2024, estimated figures for 2025, as well as forecasts for 2030. This analysis includes projections of compound annual growth rates (CAGRs) through 2030
  • Evaluation of the current market size and revenue growth prospects specific to the protein expression, accompanied by a market share analysis by system type, product, application, end user and region
  • Analysis of current and future demand in the global protein expression, along with a detailed analysis of the competitive environment, market regulations and reimbursement practices
  • Analysis of drivers, challenges and opportunities affecting market growth
  • Coverage of evolving technologies, the current and future market potential, R&D activities, growth strategies, new product pipeline, regulatory framework and reimbursement scenarios, and ESG trends of the market
  • Market share analysis of the key market participants in the protein expression industry, along with their research priorities, product portfolios, global rankings and competitive landscape
  • Profiles of the major companies, including Thermo Fisher Scientific Inc., Bio-Rad Laboratories Inc., Merck KGaA, Sartorius AG and Agilent Technologies Inc.
Product Code: BIO165B

Table of Contents

Chapter 1 Executive Summary

  • Market Outlook
  • Scope of Report
  • Market Summary
  • Market Growth Factors
  • Emerging Technologies
  • Segmental Analysis
  • Regional Analysis
  • Conclusion

Chapter 2 Market Overview

  • Technology Background
  • Protein Expression Workflow
  • Choice of Cell Type
  • Choice of Plasmid
  • Choice of Cell Expression System
  • Introduction to Protein Expression Systems
  • Protein Synthesis Machinery
  • Cloning Technologies
  • Constitutive and Inducible Promoters Commonly Used in Recombinant Protein Expression Systems
  • Production of Recombinant Proteins
  • Recombinant Protein Expression Methods
  • Comparison of Expression Systems
  • Post-Translational Processing
  • Problems Associated with the Production of Protein
  • Loss of Expression
  • Macroeconomic Factors Analysis
  • PESTEL Analysis
  • Impact of U.S. Tariff Laws on the Protein Expression Market
  • Porter's Five Forces Analysis
  • Bargaining Power of Buyers: Moderate
  • Bargaining Power of Suppliers: Moderate
  • Threat of Substitute Products: Low
  • Threat of New Entrants: Moderate
  • Industry Competition: High

Chapter 3 Market Dynamics

  • Overview
  • Market Drivers
  • Demand for Therapeutic Proteins and Biologics
  • Investments in Biopharmaceuticals
  • Technological Advances in Protein Expression Systems
  • Market Restraints
  • Complex Government Regulations and Policies
  • High Cost of Protein Drugs
  • Market Opportunities
  • Demand for Biopharmaceuticals in Emerging Countries
  • Expanded Applications for CRISPR Technology

Chapter 4 Regulatory Landscape

  • Overview
  • The U.S.
  • Europe
  • Asia-Pacific
  • Rest of the World

Chapter 5 Emerging Technologies and New Developments

  • Overview
  • CRISPR/Cas9 Genome Editing
  • Synthetic Biology
  • AI Integration in Protein Expression

Chapter 6 Market Segmentation Analysis

  • Segmentation Breakdown
  • Market Breakdown by System Type
  • Key Takeaways
  • Prokaryotic Expression Systems
  • Mammalian Cell Expression Systems
  • Yeast Expression Systems
  • Insect Cell Expression Systems
  • Cell-Free Expression Systems
  • Algal-based Expression Systems
  • Market Breakdown by Product Type
  • Key Takeaways
  • Reagents
  • Expression Vectors
  • Competent Cells
  • Instruments
  • Services
  • Market Breakdown by Application
  • Key Takeaways
  • Therapeutics
  • Industrial
  • Research
  • Market Breakdown by End User
  • Key Takeaways
  • Pharmaceutical and Biotechnology Companies
  • Contract Research Organizations
  • Academic Research Institutes
  • Others
  • Geographic Breakdown
  • Market Breakdown by Region
  • Key Takeaways
  • North America
  • Europe
  • Asia-Pacific
  • Rest of the World

Chapter 7 Competitive Intelligence

  • Key Takeaways
  • Top Companies' Ranking, 2024
  • Strategic Analysis

Chapter 8 Sustainability in the Protein Expression Market: ESG Perspective

  • Sustainability in the Protein Expression Market
  • Understanding ESG Data
  • ESG Performance Analysis
  • Environmental Performance
  • Social Performance
  • Governance Performance
  • Concluding Remarks from BCC

Chapter 9 Patent Landscape

  • Overview
  • Patents, by Year
  • Patents, by Leading Applicants
  • Patents, by Document Type
  • Recent Patents Relating to Protein Expression Technology

Chapter 10 Appendix

  • Methodology
  • References
  • Abbreviations
  • Company Profiles
  • AGILENT TECHNOLOGIES INC.
  • BIO-RAD LABORATORIES INC.
  • CORNING INC.
  • DANAHER CORP.
  • FUJIFILM CELLULAR DYNAMICS INC.
  • GENSCRIPT
  • LONZA
  • MERCK KGAA
  • NEW ENGLAND BIOLABS
  • ORIGENE TECHNOLOGIES INC.
  • PROMEGA CORP.
  • PROTEOGENIX INC.
  • QIAGEN
  • SARTORIUS AG
  • THERMO FISHER SCIENTIFIC INC.
Product Code: BIO165B

List of Tables

  • Summary Table : Global Market for Protein Expression, by Region, Through 2030
  • Table 1 : Advantages and Disadvantages of Protein Expression Systems
  • Table 2 : Prokaryotes vs. Eukaryotes Protein Synthesis
  • Table 3 : Comparison of Expression Systems
  • Table 4 : Asia-Pacific Regulatory Landscape
  • Table 5 : RoW Regulatory Landscape
  • Table 6 : Comparison of Protein Expression Systems and Their Respective Advantages and Disadvantages
  • Table 7 : Advantages, Challenges and Most Common Applications of Protein Expression Systems
  • Table 8 : Global Market for Protein Expression, by Type, Through 2030
  • Table 9 : Global Market for Prokaryotic Expression Systems, by Region, Through 2030
  • Table 10 : Global Market for Mammalian Cell Expression Systems, by Region, Through 2030
  • Table 11 : Global Market for Yeast Expression Systems, by Region, Through 2030
  • Table 12 : Global Market for Insect Cell Expression Systems, by Region, Through 2030
  • Table 13 : Global Market for Cell-Free Protein Expression Systems, by Region, Through 2030
  • Table 14 : Global Market for Algal-based Expression Systems, by Region, Through 2030
  • Table 15 : Global Market for Protein Expression, by Product, Through 2030
  • Table 16 : Global Protein Expression Market for Reagents, by Region, Through 2030
  • Table 17 : Characteristics of Commonly Used Expression Hosts
  • Table 18 : Global Protein Expression Market for Expression Vectors, by Region, Through 2030
  • Table 19 : Global Protein Expression Market for Competent Cells, by Region, Through 2030
  • Table 20 : Global Protein Expression Market for Instruments, by Region, Through 2030
  • Table 21 : Select Protein Expression Services
  • Table 22 : Global Protein Expression Market for Services, by Region, Through 2030
  • Table 23 : Global Market for Protein Expression, by Application, Through 2030
  • Table 24 : Global Protein Expression Market for Therapeutics, by Region, Through 2030
  • Table 25 : Global Protein Expression Market for Industrial Use, by Region, Through 2030
  • Table 26 : Global Protein Expression Market for Research Use, by Region, Through 2030
  • Table 27 : Global Market for Protein Expression, by End User, Through 2030
  • Table 28 : Global Protein Expression Market for Pharmaceutical and Biotechnology Companies, by Region, Through 2030
  • Table 29 : Global Protein Expression Market for Contract Research Organizations, by Region, Through 2030
  • Table 30 : Global Protein Expression Market for Academic Research Organizations, by Region, Through 2030
  • Table 31 : Global Protein Expression Market for Other End Users, by Region, Through 2030
  • Table 32 : Global Market for Protein Expression, by Region, Through 2030
  • Table 33 : North American Market for Protein Expression, by Type, Through 2030
  • Table 34 : North American Market for Protein Expression, by Product, Through 2030
  • Table 35 : North American Market for Protein Expression, by Application, Through 2030
  • Table 36 : North American Market for Protein Expression, by End User, Through 2030
  • Table 37 : North American Market for Protein Expression, by Country, Through 2030
  • Table 38 : European-based Companies' R&D Expenditures and Comparison of Their Net Sales, 2023
  • Table 39 : European Market for Protein Expression, by Type, Through 2030
  • Table 40 : European Market for Protein Expression, by Product, Through 2030
  • Table 41 : European Market for Protein Expression, by Application, Through 2030
  • Table 42 : European Market for Protein Expression, by End User, Through 2030
  • Table 43 : European Market for Protein Expression, by Country, Through 2030
  • Table 44 : Asia-Pacific Market for Protein Expression, by Type, Through 2030
  • Table 45 : Asia-Pacific Market for Protein Expression, by Product, Through 2030
  • Table 46 : Asia-Pacific Market for Protein Expression, by Application, Through 2030
  • Table 47 : Asia-Pacific Market for Protein Expression, by End User, Through 2030
  • Table 48 : Asia-Pacific Market for Protein Expression, by Country, Through 2030
  • Table 49 : RoW Market for Protein Expression, by Type, Through 2030
  • Table 50 : RoW Market for Protein Expression, by Product, Through 2030
  • Table 51 : RoW Market for Protein Expression, by Application, Through 2030
  • Table 52 : RoW Market for Protein Expression, by End User, Through 2030
  • Table 53 : RoW Market for Protein Expression, by Subregion, Through 2030
  • Table 54 : Top Companies' Ranking, 2024
  • Table 55 : Recent Developments in the Protein Expression Market, 2023-2025
  • Table 56 : Key Focus Areas in ESG Metrics
  • Table 57 : ESG Rankings for Major Protein Expression Companies, 2025*
  • Table 58 : ESG: Environmental Overview
  • Table 59 : ESG: Social Overview
  • Table 60 : ESG: Governance Overview
  • Table 61 : Patent Applications Related to Protein Expression, by Applicant, 2020-2025
  • Table 62 : Protein Expression Technology Patents Filed, 2024
  • Table 63 : Protein Expression Technology Patents Filed, 2025
  • Table 64 : Abbreviations Used in the Protein Expression Market Report
  • Table 65 : Agilent Technologies Inc.: Company Snapshot
  • Table 66 : Agilent Technologies Inc.: Financial Performance, FY 2023 and 2024
  • Table 67 : Agilent Technologies Inc.: Product Portfolio
  • Table 68 : Agilent Technologies Inc.: News/Key Developments, 2024
  • Table 69 : Bio-Rad Laboratories Inc.: Company Snapshot
  • Table 70 : Bio-Rad Laboratories Inc.: Financial Performance, FY 2023 and 2024
  • Table 71 : Bio-Rad Laboratories Inc.: Product Portfolio
  • Table 72 : Bio-Rad Laboratories Inc.: News/Key Developments, 2025
  • Table 73 : Corning Inc.: Company Snapshot
  • Table 74 : Corning Inc.: Financial Performance, FY 2023 and 2024
  • Table 75 : Corning Inc.: Product Portfolio
  • Table 76 : Danaher Corp.: Company Snapshot
  • Table 77 : Danaher Corp.: Financial Performance, FY 2023 and 2024
  • Table 78 : Danaher Corp.: Product Portfolio
  • Table 79 : Danaher Corp.: News/Key Developments, 2023-2025
  • Table 80 : FUJIFILM Cellular Dynamics Inc.: Company Snapshot
  • Table 81 : FUJIFILM Cellular Dynamics Inc.: Product Portfolio
  • Table 82 : GenScript: Company Snapshot
  • Table 83 : GenScript: Financial Performance, FY 2023 and 2024
  • Table 84 : GenScript: Product Portfolio
  • Table 85 : GenScript: News/Key Developments, 2024-2025
  • Table 86 : Lonza: Company Snapshot
  • Table 87 : Lonza: Financial Performance, FY 2023 and 2024
  • Table 88 : Lonza: Product Portfolio
  • Table 89 : Lonza: News/Key Developments, 2023-2025
  • Table 90 : Merck KGaA: Company Snapshot
  • Table 91 : Merck KGaA: Financial Performance, FY 2023 and 2024
  • Table 92 : Merck KGaA: Product Portfolio
  • Table 93 : Merck KGaA: News/Key Developments, 2023-2024
  • Table 94 : New England Biolabs: Company Snapshot
  • Table 95 : New England Biolabs: Product Portfolio
  • Table 96 : New England Biolabs: News/Key Developments, 2025
  • Table 97 : OriGene Technologies Inc.: Company Snapshot
  • Table 98 : OriGene Technologies Inc.: Product Portfolio
  • Table 99 : OriGene Technologies Inc.: News/Key Developments, 2025
  • Table 100 : Promega Corp.: Company Snapshot
  • Table 101 : Promega Corp.: Product Portfolio
  • Table 102 : Promega Corp.: News/Key Developments, 2025
  • Table 103 : ProteoGenix Inc.: Company Snapshot
  • Table 104 : ProteoGenix Inc.: Product Portfolio
  • Table 105 : Qiagen: Company Snapshot
  • Table 106 : Qiagen: Financial Performance, FY 2023 and 2024
  • Table 107 : Qiagen: Product Portfolio
  • Table 108 : Qiagen: News/Key Developments, 2023
  • Table 109 : Sartorius AG: Company Snapshot
  • Table 110 : Sartorius AG: Financial Performance, FY 2023 and 2024
  • Table 111 : Sartorius AG: Product Portfolio
  • Table 112 : Sartorius AG: News/Key Developments, 2023-2025
  • Table 113 : Thermo Fisher Scientific Inc.: Company Snapshot
  • Table 114 : Thermo Fisher Scientific Inc.: Financial Performance, FY 2023 and 2024
  • Table 115 : Thermo Fisher Scientific Inc.: Product Portfolio
  • Table 116 : Thermo Fisher Scientific Inc.: News/Key Developments, 2025

List of Figures

  • Summary Figure : Global Market Shares of Protein Expression, by Region, 2024
  • Figure 1 : Protein Expression Workflow
  • Figure 2 : PESTEL Analysis: Protein Expression Market
  • Figure 3 : Porter's Five Forces Analysis: Protein Expression Market
  • Figure 4 : Market Dynamics of Protein Expression
  • Figure 5 : Venture Capital Averages for Biopharma Therapeutics and Platform Companies, 2010-2024
  • Figure 6 : Technological Advances in Protein Expression Systems
  • Figure 7 : Emerging Technologies in the Protein Expression Market
  • Figure 8 : Global Market Shares of Protein Expression, by Type, 2024
  • Figure 9 : Global Market Shares of Protein Expression, by Product, 2024
  • Figure 10 : Global Market Shares of Protein Expression, by Application, 2024
  • Figure 11 : Global Market Shares of Protein Expression, by End User, 2024
  • Figure 12 : Global Market Shares of Protein Expression, by Region, 2024
  • Figure 13 : North American Market Shares of Protein Expression, by Country, 2024
  • Figure 14 : U.S. Elderly Population (65 and Older), Projection and Trends, 2010-2050
  • Figure 15 : European Market Shares of Protein Expression, by Country, 2024
  • Figure 16 : Asia-Pacific Market Shares of Protein Expression, by Country, 2024
  • Figure 17 : RoW Market Shares of Protein Expression, by Subregion, 2024
  • Figure 18 : How a Strong ESG Proposition Benefits Businesses
  • Figure 19 : Patents Granted Related to Protein Expression Technology, by Year, 2020-2025
  • Figure 20 : Patent Shares for Protein Expression Technology, by Document Type, 2020-2025
  • Figure 21 : Agilent Technologies Inc.: Revenue Share, by Business Unit, FY 2024
  • Figure 22 : Agilent Technologies Inc.: Revenue Share, by Country/Region, FY 2024
  • Figure 23 : Bio-Rad Laboratories Inc.: Revenue Share, by Business Unit, FY 2024
  • Figure 24 : Bio-Rad Laboratories Inc.: Revenue Share, by Country/Region, FY 2024
  • Figure 25 : Corning Inc.: Revenue Share, by Business Unit, FY 2024
  • Figure 26 : Corning Inc.: Revenue Share, by Country/Region, FY 2024
  • Figure 27 : Danaher Corp.: Revenue Share, by Business Unit, FY 2024
  • Figure 28 : Danaher Corp.: Revenue Share, by Country/Region, FY 2024
  • Figure 29 : GenScript: Revenue Share, by Business Unit, FY 2024
  • Figure 30 : GenScript: Revenue Share, by Country/Region, FY 2024
  • Figure 31 : Lonza: Revenue Share, by Business Unit, FY 2024
  • Figure 32 : Lonza: Revenue Share, by Country/Region, FY 2024
  • Figure 33 : Merck KGaA: Revenue Share, by Business Unit, FY 2024
  • Figure 34 : Merck KGaA: Revenue Share, by Country/Region, FY 2024
  • Figure 35 : Qiagen: Revenue Share, by Business Unit, FY 2024
  • Figure 36 : Qiagen: Revenue Share, by Country/Region, FY 2024
  • Figure 37 : Sartorius AG: Revenue Share, by Business Unit, 2024
  • Figure 38 : Sartorius AG: Revenue Share, by Country/Region, 2024
  • Figure 39 : Thermo Fisher Scientific Inc.: Revenue Share, by Business Unit, FY 2024
  • Figure 40 : Thermo Fisher Scientific Inc.: Revenue Share, by Country/Region, FY 2024
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