Global NGS-based RNA-sequencing Market Size Study & Forecast, by Product & Services, Technology, Application, End-User and Regional Forecasts 2022-2032

Description

The Global NGS-based RNA-sequencing Market, valued at approximately USD 3.43 billion in 2024, is poised to expand at a remarkable CAGR of 17.20% from 2025 to 2035, ultimately reaching USD 19.66 billion by the end of the forecast period. NGS-based RNA sequencing (RNA-seq) has transformed transcriptomic analysis, enabling researchers and clinicians to decode gene expression profiles, identify novel transcripts, and uncover regulatory mechanisms with unprecedented depth and accuracy. Leveraging massively parallel sequencing technologies, RNA-seq facilitates the comprehensive mapping of the transcriptome, which is critical for applications ranging from cancer research and precision medicine to developmental biology and infectious disease monitoring. This surge in adoption is driven by the escalating demand for high-throughput genomic technologies, the integration of RNA-seq in clinical diagnostics, and its indispensable role in drug discovery pipelines.

The rapid acceleration in RNA-seq usage is also underpinned by a combination of falling sequencing costs, automation in sample preparation, and advances in bioinformatics that enable researchers to process and interpret massive datasets with speed and precision. According to global genomics investment trends, billions of dollars are being funneled annually into sequencing initiatives, biobank projects, and translational research programs-many of which rely on RNA-seq for biomarker discovery and therapeutic target validation. The growing application of RNA-seq in single-cell transcriptomics and epigenetic studies is opening new frontiers for understanding cellular heterogeneity and disease progression at the molecular level. Nevertheless, challenges such as data storage, standardization of analysis pipelines, and the requirement for specialized expertise may temper growth, although these are being progressively mitigated through cloud-based analysis platforms and AI-powered annotation tools.

From a regional perspective, North America currently dominates the NGS-based RNA-sequencing market, driven by its strong network of genomic research institutions, well-funded life sciences ecosystem, and the rapid integration of sequencing into clinical workflows. The United States remains at the forefront, with significant investments in precision oncology, rare disease diagnostics, and large-scale population genomics projects. Europe follows closely, fueled by government-backed genomics initiatives, collaborative research consortia, and a strong pharmaceutical industry applying RNA-seq in drug development. Asia Pacific is forecast to register the fastest growth over the next decade, as countries such as China, Japan, and India expand their genomic infrastructure, launch national sequencing programs, and attract substantial venture capital for biotech startups. Meanwhile, Latin America and the Middle East & Africa are emerging as promising markets, with increasing adoption of RNA-seq technologies in academic research and public health genomics programs.

Major market players included in this report are:

Illumina, Inc.
Thermo Fisher Scientific Inc.
Oxford Nanopore Technologies Ltd.
Pacific Biosciences of California, Inc.
QIAGEN N.V.
BGI Genomics Co., Ltd.
Agilent Technologies, Inc.
F. Hoffmann-La Roche Ltd.
PerkinElmer, Inc.
Takara Bio Inc.
Bio-Rad Laboratories, Inc.
GenScript Biotech Corporation
Eurofins Scientific SE
Macrogen, Inc.
10x Genomics, Inc.

Global NGS-based RNA-sequencing Market Report Scope:

Historical Data - 2023, 2024
Base Year for Estimation - 2024
Forecast period - 2025-2035
Report Coverage - Revenue forecast, Company Ranking, Competitive Landscape, Growth factors, and Trends
Regional Scope - North America; Europe; Asia Pacific; Latin America; Middle East & Africa
Customization Scope - Free report customization (equivalent up to 8 analysts' working hours) with purchase. Addition or alteration to country, regional & segment scope*

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values for the coming years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within the countries involved in the study. The report also provides detailed information about crucial aspects, such as driving factors and challenges, which will define the future growth of the market. Additionally, it incorporates potential opportunities in micro-markets for stakeholders to invest, along with a detailed analysis of the competitive landscape and product offerings of key players. The detailed segments and sub-segments of the market are explained below:

By Product & Services:

Sample Preparation
Platforms & Consumables
Services
Data Analysis

By Technology:

SBS
SMRT
Nanopore

By Application:

De Novo
Epigenetics
Small RNA

By End-User:

Academic & Research Institutions
Hospitals & Clinics
Pharmaceutical & Biotechnology Companies
Other End-Users

By Region:

North America
U.S.
Canada
Europe
UK
Germany
France
Spain
Italy
Rest of Europe
Asia Pacific
China
India
Japan
Australia
South Korea
Rest of Asia Pacific
Latin America
Brazil
Mexico
Middle East & Africa
UAE
Saudi Arabia
South Africa
Rest of Middle East & Africa

Key Takeaways:

Market Estimates & Forecast for 10 years from 2025 to 2035.
Annualized revenues and regional level analysis for each market segment.
Detailed analysis of geographical landscape with Country level analysis of major regions.
Competitive landscape with information on major players in the market.
Analysis of key business strategies and recommendations on future market approach.
Analysis of competitive structure of the market.
Demand side and supply side analysis of the market.

Chapter 1. Global NGS-based RNA-sequencing Market Report Scope & Methodology

1.1. Research Objective
1.2. Research Methodology
- 1.2.1. Forecast Model
- 1.2.2. Desk Research
- 1.2.3. Top Down and Bottom-Up Approach
1.3. Research Attributes
1.4. Scope of the Study
- 1.4.1. Market Definition
- 1.4.2. Market Segmentation
1.5. Research Assumption
- 1.5.1. Inclusion & Exclusion
- 1.5.2. Limitations
- 1.5.3. Years Considered for the Study

Chapter 2. Executive Summary

2.1. CEO/CXO Standpoint
2.2. Strategic Insights
2.3. ESG Analysis
2.4. Key Findings

Chapter 3. Global NGS-based RNA-sequencing Market Forces Analysis

3.1. Market Forces Shaping The Global NGS-based RNA-sequencing Market (2024-2035)
3.2. Drivers
- 3.2.1. Rising R&D investments, translational research and clinical adoption of RNA-seq assays
- 3.2.2. Falling sequencing costs, automation in sample prep and advances in bioinformatics platforms
3.3. Restraints
- 3.3.1. Data management, storage burdens and bioinformatics complexity for large RNA-seq datasets
- 3.3.2. High capital expenditure for platforms and shortage of skilled personnel for assay implementation
3.4. Opportunities
- 3.4.1. Expansion into single-cell, spatial transcriptomics and companion diagnostic applications
- 3.4.2. Integration with cloud analytics, AI-driven interpretation and precision medicine initiatives

Chapter 4. Global NGS-based RNA-sequencing Industry Analysis

4.1. Porter's 5 Forces Model
- 4.1.1. Bargaining Power of Buyer
- 4.1.2. Bargaining Power of Supplier
- 4.1.3. Threat of New Entrants
- 4.1.4. Threat of Substitutes
- 4.1.5. Competitive Rivalry
4.2. Porter's 5 Force Forecast Model (2024-2035)
4.3. PESTEL Analysis
- 4.3.1. Political
- 4.3.2. Economical
- 4.3.3. Social
- 4.3.4. Technological
- 4.3.5. Environmental
- 4.3.6. Legal
4.4. Top Investment Opportunities
4.5. Top Winning Strategies (2025)
4.6. Market Share Analysis (2024-2025)
4.7. Global Pricing Analysis And Trends 2025
4.8. Analyst Recommendation & Conclusion

Chapter 5. Global NGS-based RNA-sequencing Market Size & Forecasts by Product & Services 2025-2035

5.1. Market Overview
5.2. Global NGS-based RNA-sequencing Market Performance - Potential Analysis (2025)
5.3. Sample Preparation
- 5.3.1. Top Countries Breakdown Estimates & Forecasts, 2024-2035
- 5.3.2. Market size analysis, by region, 2025-2035
5.4. Platforms & Consumables
- 5.4.1. Top Countries Breakdown Estimates & Forecasts, 2024-2035
- 5.4.2. Market size analysis, by region, 2025-2035
5.5. Services
- 5.5.1. Top Countries Breakdown Estimates & Forecasts, 2024-2035
- 5.5.2. Market size analysis, by region, 2025-2035
5.6. Data Analysis
- 5.6.1. Top Countries Breakdown Estimates & Forecasts, 2024-2035
- 5.6.2. Market size analysis, by region, 2025-2035

Chapter 6. Global NGS-based RNA-sequencing Market Size & Forecasts by Application 2025-2035

6.1. Market Overview
6.2. Global NGS-based RNA-sequencing Market Performance - Potential Analysis (2025)
6.3. De Novo Transcriptome Analysis
- 6.3.1. Top Countries Breakdown Estimates & Forecasts, 2024-2035
- 6.3.2. Market size analysis, by region, 2025-2035
6.4. Epigenetics & Regulatory RNA Studies
- 6.4.1. Top Countries Breakdown Estimates & Forecasts, 2024-2035
- 6.4.2. Market size analysis, by region, 2025-2035
6.5. Small RNA / miRNA Analysis
- 6.5.1. Top Countries Breakdown Estimates & Forecasts, 2024-2035
- 6.5.2. Market size analysis, by region, 2025-2035

Chapter 7. Global NGS-based RNA-sequencing Market Size & Forecasts by Region 2025-2035

7.1. NGS-based RNA-sequencing Market, Regional Market Snapshot
7.2. Top Leading & Emerging Countries
7.3. North America NGS-based RNA-sequencing Market
- 7.3.1. U.S. NGS-based RNA-sequencing Market
  - 7.3.1.1. Type breakdown size & forecasts, 2025-2035
  - 7.3.1.2. Application breakdown size & forecasts, 2025-2035
- 7.3.2. Canada NGS-based RNA-sequencing Market
  - 7.3.2.1. Type breakdown size & forecasts, 2025-2035
  - 7.3.2.2. Application breakdown size & forecasts, 2025-2035
7.4. Europe NGS-based RNA-sequencing Market
- 7.4.1. UK NGS-based RNA-sequencing Market
  - 7.4.1.1. Type breakdown size & forecasts, 2025-2035
  - 7.4.1.2. Application breakdown size & forecasts, 2025-2035
- 7.4.2. Germany NGS-based RNA-sequencing Market
  - 7.4.2.1. Type breakdown size & forecasts, 2025-2035
  - 7.4.2.2. Application breakdown size & forecasts, 2025-2035
- 7.4.3. France NGS-based RNA-sequencing Market
  - 7.4.3.1. Type breakdown size & forecasts, 2025-2035
  - 7.4.3.2. Application breakdown size & forecasts, 2025-2035
- 7.4.4. Spain NGS-based RNA-sequencing Market
  - 7.4.4.1. Type breakdown size & forecasts, 2025-2035
  - 7.4.4.2. Application breakdown size & forecasts, 2025-2035
- 7.4.5. Italy NGS-based RNA-sequencing Market
  - 7.4.5.1. Type breakdown size & forecasts, 2025-2035
  - 7.4.5.2. Application breakdown size & forecasts, 2025-2035
- 7.4.6. Rest of Europe NGS-based RNA-sequencing Market
  - 7.4.6.1. Type breakdown size & forecasts, 2025-2035
  - 7.4.6.2. Application breakdown size & forecasts, 2025-2035
7.5. Asia Pacific NGS-based RNA-sequencing Market
- 7.5.1. China NGS-based RNA-sequencing Market
  - 7.5.1.1. Type breakdown size & forecasts, 2025-2035
  - 7.5.1.2. Application breakdown size & forecasts, 2025-2035
- 7.5.2. India NGS-based RNA-sequencing Market
  - 7.5.2.1. Type breakdown size & forecasts, 2025-2035
  - 7.5.2.2. Application breakdown size & forecasts, 2025-2035
- 7.5.3. Japan NGS-based RNA-sequencing Market
  - 7.5.3.1. Type breakdown size & forecasts, 2025-2035
  - 7.5.3.2. Application breakdown size & forecasts, 2025-2035
- 7.5.4. Australia NGS-based RNA-sequencing Market
  - 7.5.4.1. Type breakdown size & forecasts, 2025-2035
  - 7.5.4.2. Application breakdown size & forecasts, 2025-2035
- 7.5.5. South Korea NGS-based RNA-sequencing Market
  - 7.5.5.1. Type breakdown size & forecasts, 2025-2035
  - 7.5.5.2. Application breakdown size & forecasts, 2025-2035
- 7.5.6. Rest of APAC NGS-based RNA-sequencing Market
  - 7.5.6.1. Type breakdown size & forecasts, 2025-2035
  - 7.5.6.2. Application breakdown size & forecasts, 2025-2035
7.6. Latin America NGS-based RNA-sequencing Market
- 7.6.1. Brazil NGS-based RNA-sequencing Market
  - 7.6.1.1. Type breakdown size & forecasts, 2025-2035
  - 7.6.1.2. Application breakdown size & forecasts, 2025-2035
- 7.6.2. Mexico NGS-based RNA-sequencing Market
  - 7.6.2.1. Type breakdown size & forecasts, 2025-2035
  - 7.6.2.2. Application breakdown size & forecasts, 2025-2035
7.7. Middle East and Africa NGS-based RNA-sequencing Market
- 7.7.1. UAE NGS-based RNA-sequencing Market
  - 7.7.1.1. Type breakdown size & forecasts, 2025-2035
  - 7.7.1.2. Application breakdown size & forecasts, 2025-2035
- 7.7.2. Saudi Arabia (KSA) NGS-based RNA-sequencing Market
  - 7.7.2.1. Type breakdown size & forecasts, 2025-2035
  - 7.7.2.2. Application breakdown size & forecasts, 2025-2035
- 7.7.3. South Africa NGS-based RNA-sequencing Market
  - 7.7.3.1. Type breakdown size & forecasts, 2025-2035
  - 7.7.3.2. Application breakdown size & forecasts, 2025-2035

Chapter 8. Competitive Intelligence

8.1. Top Market Strategies
8.2. Illumina, Inc.
- 8.2.1. Company Overview
- 8.2.2. Key Executives
- 8.2.3. Company Snapshot
- 8.2.4. Financial Performance (Subject to Data Availability)
- 8.2.5. Product/Services Port
- 8.2.6. Recent Development
- 8.2.7. Market Strategies
- 8.2.8. SWOT Analysis
8.3. Thermo Fisher Scientific Inc.
8.4. Oxford Nanopore Technologies Ltd.
8.5. Pacific Biosciences of California, Inc.
8.6. QIAGEN N.V.
8.7. BGI Genomics Co., Ltd.
8.8. Agilent Technologies, Inc.
8.9. F. Hoffmann-La Roche Ltd.
8.10. PerkinElmer, Inc.
8.11. Takara Bio Inc.
8.12. Bio-Rad Laboratories, Inc.
8.13. GenScript Biotech Corporation
8.14. Eurofins Scientific SE
8.15. Macrogen, Inc.
8.16. 10x Genomics, Inc.