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PUBLISHER: Coherent Market Insights | PRODUCT CODE: 1935257

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PUBLISHER: Coherent Market Insights | PRODUCT CODE: 1935257

CNS Specific Antisense Oligonucleotide Market, By Drug, By Indication, By Distribution Channel, By Geography

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CNS Specific Antisense Oligonucleotide Market is estimated to be valued at USD 3,200 Mn in 2026 and is expected to reach USD 6,100 Mn by 2033, growing at a compound annual growth rate (CAGR) of 9.8% from 2026 to 2033.

Report Coverage Report Details
Base Year: 2025 Market Size in 2026: USD 3,200 Mn
Historical Data for: 2020 To 2024 Forecast Period: 2026 To 2033
Forecast Period 2026 to 2033 CAGR: 9.80% 2033 Value Projection: USD 6,100 Mn

Antisense oligonucleotides are synthetic strings of nucleic acid, which reduce expression of messenger RNA (m-RNA). The function performed by interference with pre m- RNA splicing are restoration of protein and modification of protein. Antisense oligonucleotide is a new approach to treat several neurodegenerative disorders to prevent disease onset or stop disease development.

Market Dynamics

Increasing prevalence of neurodegenerative disease is a major factor driving CNS specific antisense oligonucleotide market growth. According to fact sheet from Alzheimer Association, an estimated around 5.7 million Americans were diagnosed with Alzheimer's dementia in 2018. Moreover, rich product pipeline for the treatment of CNS disorders and rare diseases associated with it is expected to boost the market growth. For instance, in December 2018, Biogen and Ionis Pharmaceuticals product IONIS-SOD1Rx (BIIB067) cleared Phase 1 clinical trial and is expected to be launched by 2020.

Key features of the study

  • This report provides in-depth analysis of the CNS specific antisense oligonucleotide market and provides market size (USD million) and Compound Annual Growth Rate (CAGR %) for the forecast period (2018 - 2026), considering 2017, as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategy adopted by key players
  • It profiles key players in the global CNS specific antisense oligonucleotide market based on the following parameters - company overview, financial performance, product portfolio, market presence, distribution strategies, key developments, strategies, and future plans
  • Key companies covered as a part of this study include, Alnylam Pharmaceuticals Inc., Sarepta Therapeutics Inc., Biogen Inc., Ionis Pharmaceuticals Inc., Wave Life Sciences Ltd., Stroke Therapeutic Inc., Dynacure, ProQR Therapeutics N.V., Q-STATE BIOSCIENCES, INC.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, technology up-gradation, market expansion, and marketing tactics
  • The global CNS specific antisense oligonucleotide market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the CNS specific antisense oligonucleotide market

Market Segmentation

  • Drug Insights (Revenue, USD Mn, 2026 - 2033)
    • Approved
    • Pipeline
  • Indication Insights (Revenue, USD Mn, 2026 - 2033)
    • Hereditary transthyretin amyloidosis (hATTR)/ Polyneuropathy
    • Spinal Muscular Atrophy
    • Huntington's Disease
  • Distribution Channel Insights (Revenue, USD Mn, 2026 - 2033)
    • Hospital Pharmacy
    • Retail Pharmacy
    • Online Pharmacy
  • Regional Insights (Revenue, USD Mn, 2026 - 2033)
    • North America
    • U.S.
    • Canada
    • Latin America
    • Brazil
    • Argentina
    • Mexico
    • Rest of Latin America
    • Europe
    • Germany
    • U.K.
    • France
    • Italy
    • Russia
    • Rest of Europe
    • Asia Pacific
    • China
    • India
    • Japan
    • Australia
    • South Korea
    • ASEAN
    • Rest of Asia Pacific
    • Middle East
    • GCC
    • Israel
    • Rest of Middle East
    • Africa
    • North Africa
    • Central Africa
    • South Africa
  • Key Players Insights
    • Alnylam Pharmaceuticals Inc.
    • Sarepta Therapeutics Inc.
    • Biogen Inc.
    • Ionis Pharmaceuticals Inc.
    • Wave Life Sciences Ltd.
    • Stroke Therapeutic Inc.
    • Dynacure
    • ProQR Therapeutics N.V.
    • Q-STATE BIOSCIENCES, INC.
Product Code: CMI2477

Table of Contents

1. Research Objectives and Assumptions

  • Research Objectives
  • Assumptions
  • Abbreviations

2. Market Overview

  • Report Description
    • Market Definition and Scope
  • Executive Summary
    • Global CNS Specific Antisense Oligonucleotide Market, By Drug
    • Global CNS Specific Antisense Oligonucleotide Market, By Indication
    • Global CNS Specific Antisense Oligonucleotide Market, By Distribution Channel
    • Global CNS Specific Antisense Oligonucleotide Market, By Region

3. Market Dynamics, Regulations, and Trends Analysis

  • Market Dynamics
  • Impact Analysis
  • Key Highlights
  • Regulatory Scenario
  • Product Launches/Approvals
  • PEST Analysis
  • PORTER's Analysis
  • Market Opportunities
  • Regulatory Scenario
  • Key Developments
  • Industry Trend

4. Global CNS Specific Antisense Oligonucleotide Market, By Drug, 2020-2033, (USD Mn)

  • Introduction
    • Market Share Analysis, 2026 and 2033 (%)
    • Y-o-Y Growth Analysis, 2021 - 2033
    • Segment Trends
  • Approved
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2033, (USD Mn)
  • Pipeline
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2033, (USD Mn)

5. Global CNS Specific Antisense Oligonucleotide Market, By Indication, 2020-2033, (USD Mn)

  • Introduction
    • Market Share Analysis, 2026 and 2033 (%)
    • Y-o-Y Growth Analysis, 2021 - 2033
    • Segment Trends
  • Hereditary transthyretin amyloidosis (hATTR)/ Polyneuropathy
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2033, (USD Mn)
  • Spinal Muscular Atrophy
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2033, (USD Mn)
  • Huntington's Disease
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2033, (USD Mn)

6. Global CNS Specific Antisense Oligonucleotide Market, By Distribution Channel Type, 2020-2033, (USD Mn)

  • Introduction
    • Market Share Analysis, 2026 and 2033 (%)
    • Y-o-Y Growth Analysis, 2021 - 2033
    • Segment Trends
  • Hospital Pharmacy
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2033, (USD Mn)
  • Retail Pharmacy
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2033, (USD Mn)
  • Online Pharmacy
    • Introduction
    • Market Size and Forecast, and Y-o-Y Growth, 2020-2033, (USD Mn)

7. Global CNS Specific Antisense Oligonucleotide Market, By Region, 2020 - 2033, Value (USD Mn)

  • Introduction
    • Market Share (%) Analysis, 2026, 2028 & 2033, Value (USD Mn)
    • Market Y-o-Y Growth Analysis (%), 2021 - 2033, Value (USD Mn)
    • Regional Trends
  • North America
    • Introduction
    • Market Size and Forecast, By Drug, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Indication, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Distribution Channel, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Country, 2020 - 2033, Value (USD Mn)
      • U.S.
      • Canada
  • Latin America
    • Introduction
    • Market Size and Forecast, By Drug, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Indication, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Distribution Channel, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Country, 2020 - 2033, Value (USD Mn)
      • Brazil
      • Argentina
      • Mexico
      • Rest of Latin America
  • Europe
    • Introduction
    • Market Size and Forecast, By Drug, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Indication, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Distribution Channel, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Country, 2020 - 2033, Value (USD Mn)
      • Germany
      • U.K.
      • Spain
      • France
      • Italy
      • Russia
      • Rest of Europe
  • Asia Pacific
    • Introduction
    • Market Size and Forecast, By Drug, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Indication, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Distribution Channel, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Country, 2020 - 2033, Value (USD Mn)
      • China
      • India
      • Japan
      • Australia
      • South Korea
      • ASEAN
      • Rest of Asia Pacific
  • Middle East
    • Introduction
    • Market Size and Forecast, By Drug, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Indication, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Distribution Channel, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Country, 2020 - 2033, Value (USD Mn)
      • GCC Countries
      • Israel
      • Rest of Middle East
  • Africa
    • Introduction
    • Market Size and Forecast, By Drug, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Indication, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Distribution Channel, 2020 - 2033, Value (USD Mn)
    • Market Size and Forecast, By Country, 2020 - 2033, Value (USD Mn)
      • South Africa
      • North Africa
      • Central Africa

8. Competitive Landscape

  • Alnylam Pharmaceuticals Inc.
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Sarepta Therapeutics Inc.
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Biogen Inc.
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Ionis Pharmaceuticals Inc.
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Wave Life Sciences Ltd.
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Stroke Therapeutic Inc.
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Dynacure
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • ProQR Therapeutics N.V.
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies
  • Q-STATE BIOSCIENCES, INC.
    • Company Highlights
    • Product Portfolio
    • Key Developments
    • Financial Performance
    • Strategies

9. Analyst Recommendations

  • Wheel of Fortune
  • Analyst View
  • Coherent Opportunity Map

10. References and Research Methodology

  • References
  • Research Methodology
  • About us
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