PUBLISHER: DelveInsight | PRODUCT CODE: 1096485
PUBLISHER: DelveInsight | PRODUCT CODE: 1096485
DelveInsight's, "Ischemic Stroke - Pipeline Insight, 2022," report provides comprehensive insights about 50+ companies and 50+ pipeline drugs in Ischemic Stroke pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Ischemic Stroke Understanding
Ischemic Stroke: Overview
Ischemic strokes occur when blood supply is cut off to part of the brain. This type of stroke accounts for the majority of all strokes. The blocked blood flow in an ischemic stroke may be caused by a blood clot or by atherosclerosis, a disease which causes narrowing of the arteries over time. Ischemic strokes can be caused by a blockage anywhere along the arteries feeding the brain. Immediate emergency treatment is critical to surviving a stroke with the least amount of damage to the brain and ability to function. Ischemic strokes occur when blood supply is cut off to part of the brain by a blood clot or narrowing of the arteries. Blood clots may be caused by an irregular heartbeat such as arrhythmia, problems with the heart valve, infection of the heart muscle, hardening of the arteries, blood-clotting disorders, inflammation of the blood vessels, or a heart attack. A less common cause of ischemic stroke occurs when blood pressure becomes too low (hypotension), reducing blood flow to the brain. This usually occurs with narrowed or diseased arteries. Low blood pressure can result from a heart attack, large loss of blood or severe infection. Each of these conditions affects the flow of blood through the heart and blood vessels and increases the risk of stroke. Strokes can happen to a person of any age, including children. However, the older a person is, the higher their risk of stroke. Strokes are more common in men, but more women die from them. A family history of stroke, or a personal history of stroke or heart attack, also increase the risk of stroke. Research also has shown African-Americans are at higher risk of stroke than Caucasians. People who have symptoms of a stroke need emergency medical care. Immediate medical attention may prevent life-threatening complications, more widespread brain damage, and is critical for the recovery.
"Ischemic Stroke - Pipeline Insight, 2022" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Ischemic Stroke pipeline landscape is provided which includes the disease overview and Ischemic Stroke treatment guidelines. The assessment part of the report embraces, in depth Ischemic Stroke commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Ischemic Stroke collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Ischemic Stroke Emerging Drugs Chapters
This segment of the Ischemic Stroke report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Ischemic Stroke Emerging Drugs
The company is developing MultiStem®, a proprietary stem cell product, for the treatment of diseases and conditions in the neurological, inflammatory and immune, and cardiovascular disease areas, as well as other indications. Factors expressed by MultiStem have the potential to deliver a therapeutic benefit in several ways, such as reducing inflammation, protecting damaged or injured tissue, and enhancing the formation of new blood vessels in regions of ischemic injury. These cells exhibit a drug-like profile in that they act primarily through the production of multiple factors that regulate the immune system, protect damaged or injured cells, promote tissue repair and healing, and the cells are subsequently cleared from the body over time. Currently, it is in Phase III stage of clinical trial evaluation to treat Ischemic Stroke.
Elezanumab (ABT 555) is a fully humanised monoclonal antibody, inhibiting repulsive guidance molecule a (RGMa), being developed by AbbVie, for the treatment of spinal cord injuries and acute ischemic stroke. Currently, it is in Phase II stage of clinical trial evaluation to treat acute ischemic stroke.
LT3001, a novel molecule designed to restore occluded blood flow without causing hemorrhage, holds promise as a superior and safer therapy to expand the treatable population and improved the outcome after acute ischemic stroke.
RNS60, is being developed to treat chronic neurodegenerative diseases driven by mitochondrial dysfunction, such as amyotrophic lateral sclerosis (ALS), and to improve recovery from neurological trauma, such as ischemic stroke. RNS60 uniquely activates intracellular signaling pathways that have anti-inflammatory effects and promote mitochondrial biogenesis, cell survival, and differentiation. In addition to protecting neurons and oligodendrocytes in the central nervous system, RNS60 modulates the activity of immune cells to restore cellular homeostasis throughout the body - without the undesirable side effects common to so many of today's medicines.
Further product details are provided in the report……..
Ischemic Stroke: Therapeutic Assessment
This segment of the report provides insights about the different Ischemic Stroke drugs segregated based on following parameters that define the scope of the report, such as:
There are approx. 50+ key companies which are developing the therapies for Ischemic Stroke. The companies which have their Ischemic Stroke drug candidates in the most advanced stage, i.e. phase III include Athersys, Inc.
DelveInsight's report covers around 50+ products under different phases of clinical development like
Ischemic Stroke pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Products have been categorized under various Molecule types such as
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
Ischemic Stroke: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Ischemic Stroke therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Ischemic Stroke drugs.
Key Questions
Current Treatment Scenario and Emerging Therapies:
Key Players
Key Products