PUBLISHER: DelveInsight | PRODUCT CODE: 1173608
PUBLISHER: DelveInsight | PRODUCT CODE: 1173608
"LNZ101/LNZ100 Emerging Drug Insight and Market Forecast - 2032" report provides comprehensive insights about LNZ101/LNZ100 for Presbyopia in the 7MM. A detailed picture of the LNZ101/LNZ100 for Presbyopia in the 7MM, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan, for the study period 2019-2032 is provided in this report along with a detailed description of the LNZ101/LNZ100 for Presbyopia. The report provides insight about mechanism of action, dosage and administration, as well as research and development activity including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the LNZ101/LNZ100 market forecast, analysis for Presbyopia in the 7MM, descriptive analysis such as SWOT, analyst views, comprehensive overview of market competitors, and brief about other emerging therapies in Presbyopia.
LNZ100, a 1.75% aceclidine formulation being developed by LENZ Therapeutics, is the first and only aceclidine-based eye drop with the promise of provide seamless vision for the vast majority of all presbyopes.
Aceclidine is a small molecule acetylcholinesterase receptor agonist that causes pupil contraction, or miosis, creating a pinhole effect that improves near vision. Studies have shown that aceclidine's mechanism of action is different from its competitors due to its ability to create a pinhole pupil effect while avoiding myopic shift. It is crucial to minimize myopic shift as it can significantly impair distance vision for a majority of presbyopes.
Aceclidine has a unique MOA, in which miosis is decoupled from the myopic shift, which is expected to allow it to target the broadest patient population.
Lenz Therapeutics is also developing another formulation, LNZ101 (1.75% Aceclidine with Brimonidine), for the treatment of presbyopia with the potential for increased duration of treatment and an added benefit of eye whitening.
Both formulations use a proprietary, preservative-free vehicle matrix to maximize comfort, efficiency, and bioavailability. LENZ Therapeutics plans to start its pivotal Phase III trial. This trial will include both the eye drop formulations for presbyopia.
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.
This report provides a detailed market assessment of LNZ101/LNZ100 in Presbyopia in the 7MM, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan. This segment of the report provides forecasted sales data from 2025 to 2032.
The report provides the clinical trials information of LNZ101/LNZ100 in Presbyopia covering trial interventions, trial conditions, trial status, start and completion dates.