PUBLISHER: DelveInsight | PRODUCT CODE: 1397392
PUBLISHER: DelveInsight | PRODUCT CODE: 1397392
"CALQUENCE Emerging Drug Insight and Market Forecast - 2032" report provides comprehensive insights about CALQUENCE for Diffuse Large B-cell lymphoma (DLBCL) in the seven major markets. A detailed picture of the CALQUENCE for DLBCL in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the CALQUENCE for DLBCL. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the CALQUENCE market forecast analysis for DLBCL in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in DLBCL.
CALQUENCE (acalabrutinib) is a next-generation, selective inhibitor of Bruton's tyrosine kinase (BTK). CALQUENCE binds covalently to BTK, thereby inhibiting its activity. In B cells, BTK signaling activates pathways necessary for B-cell proliferation, trafficking, chemotaxis, and adhesion.
AstraZeneca and Acerta Pharma are currently evaluating CALQUENCE in more than 20 company-sponsored clinical trials as part of an extensive clinical development program. CALQUENCE is being evaluated for treating multiple B-cell blood cancers, including DLBCL, CLL, MCL, Waldenstrom's macroglobulinemia, follicular lymphoma, and marginal zone lymphoma (AstraZeneca, 2022b).
AstraZeneca and Acerta Pharma are evaluating CALQUENCE under an extensive clinical development program. The Phase III trial evaluates acalabrutinib in combination with R-CHOP with previously untreated non-germinal center DLBCL (activated B-cell [ABC] and unclassified). The drug in combination with RICE (rituximab, ifosfamide, carboplatin, and etoposide) in the Phase II trial is also evaluated as second-line therapy in relapsed/refractory DLBCL. The combination of acalabrutinib and axicabtagene ciloleucel in Phase I/II is being evaluated as the third line of therapy in treating patients with B-cell lymphoma, including R/R DLBCL.
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.
This report provides a detailed market assessment of CALQUENCE for Diffuse Large B-cell lymphoma (DLBCL) in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2027 to 2032.
The report provides the clinical trials information of CALQUENCE for DLBCL covering trial interventions, trial conditions, trial status, start and completion dates.