PUBLISHER: DelveInsight | PRODUCT CODE: 1462271
PUBLISHER: DelveInsight | PRODUCT CODE: 1462271
"TEPEZZA Market Size, Forecast, and Market Insight - 2032" report provides comprehensive insights about TEPEZZA for Graves' Ophthalmopathy in the seven major markets. A detailed picture of the TEPEZZA for Graves' Ophthalmopathy in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the TEPEZZA for Graves' Ophthalmopathy. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the TEPEZZA market forecast analysis for Graves' Ophthalmopathy in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in Graves' Ophthalmopathy.
Teprotumumab, an insulin-like growth factor-1 receptor inhibitor (IGF-1R), is a fully human IgG1 monoclonal antibody produced in Chinese hamster ovary (CHO-DG44) cells with a molecular weight of approximately 148 KD.
The metabolism of teprotumumab has not been fully characterized; however, it is expected to undergo metabolism via proteolysis. TEPEZZA for injection is supplied as a sterile, preservative-free, and white to off-white, lyophilized powder for IV infusions. Each single-dose vial contains 500 mg of teprotumumab, L-histidine (7.45 mg), L-histidine hydrochloride monohydrate (31.8 mg), polysorbate 20 (1 mg), and trehalose dihydrate (946 mg). After reconstitution with 10 mL of sterile water for injection, USP, the final concentration is 47.6 mg/mL with a pH of 5.5.
The recommended dose of TEPEZZA is an IV infusion of 10 mg/kg for the initial dose, followed by an IV infusion of 20 mg/kg every 3 weeks for seven additional infusions.
Teprotumumab's mechanism of action in patients with Graves' Ophthalmopathy has not been fully characterized. It binds to IGF-1R and blocks its activation and signaling.
The report provides insights into:
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.
TEPEZZA Analytical Perspective by DelveInsight
This report provides a detailed market assessment of TEPEZZA for Graves' Ophthalmopathy in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2024 to 2032.
The report provides the clinical trials information of TEPEZZA for Graves' Ophthalmopathy covering trial interventions, trial conditions, trial status, start and completion dates.