PUBLISHER: DataM Intelligence | PRODUCT CODE: 1382550
PUBLISHER: DataM Intelligence | PRODUCT CODE: 1382550
Perennial rhinitis can be defined clinically as an inflammatory condition of the nose characterised by nasal obstruction, sneezing, itching, or rhinorrhoea, occurring for an hour or more on most days throughout the year. Rhinitis is commonly managed by both primary and secondary care physicians. Although most cases can be diagnosed and treated in primary care, referral to secondary care is often necessary when patients do not respond to treatment or other diagnoses are suspected.
A global disease allergic rhinitis (AR) affects a huge proportion of people around the world. Allergic rhinitis is diagnosed with a group of symptoms affecting the nose. These symptoms occur when people breathe in something they are allergic to, such as dust, animal dander or pollen.
Changes in genetic factors are unlikely to be the underlying cause of the rise in allergic diseases since the increases in allergic rhinitis and asthma occurred relatively rapidly. Instead, multiple environmental factors may have played a role. These include improvements in hygiene, eradication of most parasitic worm infections, changes in home heating and ventilation, and a decline in physical activity and alterations in diet due to lifestyle changes.
The rise in the prevalence of allergic rhinitis is one of the significant key factors that drive the saline spray market during the forecast period. For instance, according to the article published in the National Library of Medicine 2023, the prevalence of AR cases ranged from 1.83 to 9.23% between 2017 and 2022. There was a significant drop of 21.38 to 70.22% between the pre- and post-COVID-19 pandemic. Males were more prevalent in the 6 to 18-year-olds than females. Thus, the above factors help to drive market growth during the forecast period.
Furthermore, ongoing extensive R&D activities for the development of more effective products and formulations, changes in environmental conditions, increasing pollution, rising number of patients, and changes in lifestyle are proving the major driving factors for the perennial allergic rhinitis market.
Allergic rhinitis is a serious health condition that can lead to sleep disturbances, fatigue, irritability, depression, and difficulty paying attention. If left untreated, it can become chronic and lead to complications such as nasal inflammation, sinusitis, otitis media, sleep apnea, upper respiratory tract infection, dental problems, and eustachian tube dysfunction. It is also linked to increased chances of developing asthma, flares, worsening symptoms, and difficult-to-control asthma in those with existing asthma.
The global perennial allergic rhinitis drugs market is segmented based on drug class, route of administration, distribution channel and region.
The anti-histamines segment from the drug class segment accounted for approximately 41.7% and it is expected to be dominated during the forecast period. Antihistamines are a pharmaceutical class of drugs that act to treat histamine-mediated conditions. There are two main classes of histamine receptors: H-1 receptors and H-2 receptors. Antihistamine drugs that bind to H-1 receptors are generally used to treat allergies and allergic rhinitis.
For instance, in June 2021, the U.S. Food and Drug Administration approved a nasal antihistamine for nonprescription use through a process called a partial prescription to nonprescription switch. The FDA approved Astepro (azelastine hydrochloride nasal spray, 0.15%) for seasonal and perennial allergic rhinitis-commonly known as allergies-for adults and children six years of age and older.
Europe is estimated to hold about 31.4% of the total market share throughout the forecast period, owing to the rise in the prevalence of perennial allergic rhinitis, novel drug launches, rise in research and development, well-established market players, collaborations and acquisition with key players and others help this region to be having highest market share during the forecast period.
For instance, in April 2021, Glenmark Pharma stated that it is concluding the final, national phase of its marketing approval application process to launch its nasal spray Ryaltris in 17 countries in the European Union (EU). Glenmark said Ryaltris is now approved in Europe for the first-line treatment of allergic rhinitis in patients over 12 years of age. Ryaltris is indicated for symptomatic treatment of seasonal and perennial allergic rhinitis in adults and children over 12 years of age. The drug relieves symptoms of allergic rhinitis, including stuffy nose, runny nose, nasal itching, sneezing, as well as itchy, red and watery eyes.
A study conducted by an investigative otolaryngology group they found that many patients with allergic rhinitis symptoms worsened due to increased exposure to indoor allergens and discontinuation of immunotherapy during COVID-19 lockdowns. The study emphasizes the importance of long-term management, primary prevention, and control through allergen avoidance measures, pharmacotherapy, and allergen-SIT. Environmental factors are critical in AR pathogenesis, and immunotherapy remains the only treatment that alters the disease's natural history.
By Route of Administration
major global players in the market include: AdenHealthcare, Niprojmipharma, Krosyl Pharma, Sanis Health Inc, Hanmi Pharma, Johnson & Johnson Consumer Inc, Bristol Laboratories Ltd, GSK, Nutra Respiro, Bayer Canada and among others.
The global perennial allergic rhinitis drugs market report would provide approximately 61 tables, 58 figures and 187 Pages.
LIST NOT EXHAUSTIVE